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Nutritional status in relation to lifestyle in patients with compensated viral cirrhosis

World Journal of Gastroenterology 2012年第40期18卷 5759-5770页

作者： Fumikazu Hayashi Chika Momoki Miho Yuikawa Yuko Simotani Etsushi Kawamura Atsushi Hagihara Hideki Fujii sawako kobayashi Shuji Iwai Hiroyasu Morikawa Masaru Enomoto Akihiro Tamori Norifumi Kawada Satoko Ohfuji Wakaba Fukusima Daiki Habu Department of Medical Nutrition Graduate School of Life ScienceOsaka City University Department of Hepatology Graduate School of MedicineOsaka City University Department of Hepatology Graduate School of MedicineOsaka City UniversityOsaka 545-8585Japan Department of Public Health Graduate School of MedicineOsaka City University

AIM:To assess the nourishment status and lifestyle of non-hospitalized patients with compensated cirrhosis by using noninvasive ***:The subjects for this study consisted of 27 healthy volunteers,59 patients with chronic viral hepatitis,and 74 patients with viral cirrhosis,from urban *** assessed the biochemical blood tests,anthropometric parameters,diet,lifestyle and physical activity of the patients.A homeostasis model assessment-insulin resistance(HOMA-IR) value of ≥ 2.5 was considered to indicate insulin *** measured height,weight,waist circumference,arm circumference,triceps skin-fold thickness,and handgrip strength,and calculated body mass index,arm muscle circumference(AMC),and arm muscle area(AMA).We interviewed the subjects about their dietary habits and lifestyle using health assessment computer *** surveyed daily physical activity using a *** and multivariate logistic regression modeling were used to identify the relevant factors for insulin ***:The rate of patients with HOMA-IR ≥ 2.5(which was considered to indicate insulin resistance) was 14(35.9%) in the chronic hepatitis and 17(37.8%) in the cirrhotic ***(%)(control vs chronic hepatitis,111.9% ± 10.5% vs 104.9% ± 10.7%,P = 0.021;control vs cirrhosis,111.9% ± 10.5% vs 102.7% ± 10.8%,P = 0.001) and AMA(%)(control vs chronic hepatitis,128.2% ± 25.1% vs 112.2% ± 22.9%,P = 0.013;control vs cirrhosis,128.2% ± 25.1% vs 107.5% ± 22.5%,P = 0.001) in patients with chronic hepatitis and liver cirrhosis were significantly lower than in the control *** strength(%) in the cirrhosis group was significantly lower than in the controls(control vs cirrhosis,92.1% ± 16.2% vs 66.9% ± 17.6%,P < 0.001).The results might reflect a decrease in muscle *** total nutrition intake and amounts of carbohydrates,protein and fat were not significantly different amongst the *** activity levels(kcal/d)(control vs cirrhosis,210 ± 11

关键词：生活方式营养状况肝硬化病毒性 logistic回归模型患者胰岛素抵抗慢性肝炎

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Number and distribution of eosinophils and lymphocytes in the Japanese pediatric gastrointestinal tract:in search of a definition for"abnormally increased eosinophils"

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World Journal of Pediatrics 2023年第3期19卷 251-260页

作者： Mai Iwaya Shota kobayashi Yoshiko Nakayama sawako Kato Shingo Kurasawa Tomomitsu Sado Yugo lwaya Takeshi Uehara Hiroyoshi Ota Department of Laboratory Medicine Shinshu University Hospital3-1-1 AsahiMatsumotoNaganoJapan Department of Pediatrics Shinshu University School of MedicineMatsumotoJapan Division of Gastroenterology and Hepatology Department of MedicineShinshu University School of MedicineMatsumotoJapan Department of Laboratory Medicine Shinshu University School of MedicineMatsumotoJapan Department of Clinical Laboratory Sciences School of Health SciencesShinshu UniversityMatsumotoJapan

Background Primary eosinophilic gastrointestinal disorders(EGIDs)constitute chronic allergic *** number of eosinophils is one of the diagnostic criteria;more than 20 eosinophils per high-power field(HPF)in the gastrointestinal(GI)tract are considered abnormal in ***,the quantity of eosinophils considered normal varies according to anatomical location and geographical region;such values have not been reported in Japanese pediatric patients,nor have the numbers of lymphocytes in the normal pediatric *** establish a reference for defining diagnostic criteria for EGIDs,we evaluated the number of eosinophils in the normal Japanese pediatric GI *** We examined 131 biopsy cases without significant clinical history,endoscopic abnormality,or histological *** analysis of CD3 and CD20 was *** The mean eosinophil density was highest in the cecum(49.5±22.4 per HPF).Counts of more than 20 eosinophils per HPF were observed in the duodenum[bulb(20.0±9.6)and second portion(30.0±15.8)],terminal ileum(38.3±22.7),cecum(49.5±22.4),ascending colon(42.3±25.3),transverse colon(29.4±17.0),and descending colon(32.2±17.9).Counts of fewer than 10 eosinophils per HPF were observed in the stomach and rectum;a count of fewer than one eosinophil per HPF was observed in the *** than 100 CD3-positive T cells per HPF were observed in the *** The mean numbers of eosinophils in the bowel were greater than 20 per *** Japanese pediatrics,the cur-rent threshold eosinophil count should be revised.

关键词： Eosinophil Gastrointestinal tract Japanese Lymphocyte Normal Pediatrics

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Tolerance and acceptance of hepatic venous pressure gradient measurement in cirrhosis(CHESS1904):An international multicenter study

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Portal Hypertension & Cirrhosis 2022年第1期1卷 7-14页

作者： Jun‐Hui Sun He Zhao Haijun Zhang Lei Li NecatiÖrmeci Zi‐Niu Yu Xun Li Shuangxi Li Xujun Yang Huaping Wei Xiaoliang Zhu Zhengcong Zhang Yajin Wang Zhongwei Zhao Jianting Mao Qiaohong Wu Xiaole Sun Huiling Xiang Kefeng Jia Chao Yang Wei Wu Xiuqing Lin Haixin Yao Changzeng Zuo Jitao Wang Bo Zhang Chunqing Zhang Xiaoling Wu Guangchuan Wang Shengjuan Yao Ruihang Wang Li Zhou Hui Huan Qingli Tu Xue Pu Feng Zhang Qin Yin Linpeng Zhang Ying Guo Jian Wang Kohei Kotani sawako Uchida‐kobayashi Norifumi Kawada He Zhu Li Li Wei Wang Guo Zhang Lei Yu Xudong Cui Qingliang Zhu Hailong Zhang Xiaoli Hu Rafael OXimenes Adriano Gonçalves de Araújo Giulliano Gardenghi Yubao Zheng Zebin Wu Mingsheng Huang Xiaoyong Chen Jun Wu Feng Xie Yang Bo Shengjuan Hu Linke Ma Xiao Li Xiaolong Qi Hepatobiliary and Pancreatic Interventional Treatment Center Division of Hepatobiliary and Pancreatic SurgeryThe First Affiliated HospitalZhejiang University School of MedicineZhejiang Clinical Research Center of Hepatobiliary and Pancreatic DiseasesZhejiang Provincial Research Center for Diagnosis and Treatment of Heapatobiliary DiseasesZhejiang University Cancer CenterHangzhouZhejiangChina Department of Interventional Therapy National Cancer Center/National Clinical Research Center/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Institute of Portal Hypertension Department of General SurgeryThe First Hospital of Lanzhou UniversityLanzhouGansuChina Department of Anesthesiology and Operating Theater The First Hospital of Lanzhou UniversityLanzhouGansuChina Interventional Radiology Department The First Hospital of Lanzhou UniversityLanzhouGansuChina Department of Gastroenterology Ankara University School of MedicineAnkaraTurkey Department of Internal Medicine Istanbul Health and Technology University Medical SchoolIstanbulTurkey Department of General Surgery Key Laboratory of Biotherapy and Regenerative Medicine of Gansu ProvinceThe First Hospital of Lanzhou UniversityLanzhouGansuChina Nursing Department The First Hospital of Lanzhou UniversityLanzhouGansuChina Department of General Surgery Donggang BranchFirst Hospital of Lanzhou UniversityLanzhouGansuChina The Diagnosis and Treatment Center of Endoscopy and Interventional Radiology Department of General SurgeryDonggang BranchFirst Hospital of Lanzhou UniversityLanzhouGansuChina Department of Interventional Radiology Lishui Central HospitalLishuiZhejiangChina Department of Hepatology and Gastroenterology of The Third Central Hospital of Tianjin TianjinChina Department of Radiology of The Third Central Hospital of Tianjin TianjinChina Department of Gastroenterology The First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiangChina Department of Hepatobiliar

Aim:To determine the tolerance and acceptance of hepatic venous pressure gradient(HVPG)measurements in patients with liver ***:This prospective international multicenter study included 271 patients with cirrhosis who were scheduled to undergo HVPG measurement between October 2019 and June *** related to the tolerance and acceptance of HVPG measurements were collected using descriptive ***:HVPG measurements were technically successful in all 271 patients,with 141(52.0%)undergoing HVPG measurement *** complication rate was 0.4%.Postoperative pain was significantly lower than preoperative expected pain(p<0.001)and intraoperative pain(p<0.001),and intraoperative pain was also significantly lower than preoperative expected pain(p=0.036).No,mild,moderate,severe,and intolerable discomfort scores were reported by 36.9%,44.6%,11.1%,6.3%,and 0.4%of these patients,respectively,during HVPG measurement and by 54.6%32.5%,11.4%,1.5%,and 0%,respectively,after HVPG *** these patients,39.5%had little understanding and 10%had no understanding of the value of HVPG measurement,with 35.1%and 4.1%regarding HVPG measurements as being of little or no help,*** patients reported that they would definitely(15.5%),probably(46.9%),or possibly(29.9%)choose to undergo additional HVPG measurements again,and 62.7%regarded the cost of the procedure as ***:HVPG measurement was safe and well‐tolerated in patients with cirrhosis,but patient education and communication are warranted to improve the acceptance of this procedure.

关键词： design hypertension multicenter study portal pressure prospective study questionnaire wedge

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