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Small-diameter vertical shafts constructed in the shallow space of steep mountainous areas

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Underground Space 2019年第3期4卷 235-250页

作者： t.Hara A.Yashima K.sawada K.Kariya H.tsuji N.Soga University of toyama Japan Gifu University Japan Eight Kogyo Co.Ltd. Japan

Japan is a mountainous country comprising several islands,in which mountains occupy 70%of the entire ***,numerous transmission line towers have been constructed in the shallow space of steep mountainous *** such construction,monorails and/or cableways are generally used to transport materials and equipment to the construction site instead of using a construction road,as the former method is more economically ***,with this method,drill rigs or vertical shaft sinking machines cannot be transported to the *** small-diameter vertical shafts of 2.5 or 3.0 m as the foundation for high-voltage transmission line towers in mountainous areas are traditionally constructed manually in *** the past two decades,however,dangerous and poor environmental conditions for workers regarding the manual construction of these small-diameter vertical shafts have become a major ***,owing to the poor environmental conditions of small-diameter vertical shafts to be constructed in the shallow space of steep mountainous areas,a decrease has occurred in the number of young workers entering these ***,the construction of transmission line towers with using the manually traditional small-diameter vertical shafts is becoming difficult in Japan from abovementioned *** development of a new technology to solve the problems is necessary for Japan’s economic *** this knowledge,the authors have developed a new small-diameter vertical shaft construction system,in which workers do not have to enter the vertical shaft during construction,as machines are used *** applicability of the proposed system was confirmed by means of the construction of three actual vertical shafts at two construction sites,as well as in factory and field *** applicability and details of the final proposed system are summarized in this paper.

关键词： Small-diameter vertical shaft Shallow space Steep mountainous area

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牛体内催乳素释放对猪毛菜碱的响应

饲料博览 2010年第4期 50-50页

作者： Hashizume J sawada t Yaegashi t Saito H Ezzat Ahmed A Goto Y Nakajima Y Jin J Kasuya E Nagy G M

试验研究了猪毛菜碱(一种内源性多巴胺化合物)对牛体内催乳素释放的影响。试验以小牛和母牛为研究对象,试验日期为4月到6月。尽管对生理盐水的响应程度比猪毛菜碱小,但单独静脉注射生理盐水(5mg·kg-1)或猪毛菜碱(1DA受体拮抗剂,0.1mg·... 详细信息

试验研究了猪毛菜碱(一种内源性多巴胺化合物)对牛体内催乳素释放的影响。试验以小牛和母牛为研究对象,试验日期为4月到6月。尽管对生理盐水的响应程度比猪毛菜碱小,但单独静脉注射生理盐水(5mg·kg-1)或猪毛菜碱(1DA受体拮抗剂,0.1mg·kg-1),却显著促进了雄性和雌性小母牛催乳素的释放(P<0.05)。雌性小牛和雄性小牛的催乳素对生理盐水及猪毛菜碱的响应模式是相似的。在母牛体内单独注射生理盐水或猪毛菜碱显著促进了奶牛体内催乳素的释放(P<0.05)。生理盐水和猪毛菜碱混合注射,对奶牛体内的催乳素的释放无显著影响。单独脑室内注射生理盐水(10mg·头-1),显著促进了去势犊牛催乳素的释放(P<0.05)。结果表明,不论是雌性、雄性小牛,还是在奶牛体内,生理盐水都参与了催乳素的释放过程。研究结果表明,催乳素对生理盐水的释放潜力与牛的生理状态不一致。

关键词：猪毛菜碱催乳素牛多巴胺

平扫t1加权MR影像齿状核高信号与脑部放射相关性的研究

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国际医学放射学杂志 2011年第2期 173-173页

作者： S.Kasahara Y.Miki M.Kanagaki A.Yamamoto N.Mori t.sawada 高莉 Department of Diagnostic Imaging and Nuclear Medicine Graduate School of MedicineKyoto University

目的评价t1加权MRI中齿状核高信号的发生率,确定这种高信号和临床因素(包括脑部放疗病史)的相关性。材料与方法此项研究由医院伦理委员会批准,获得每例

关键词：高信号齿状核脑部 t1 MR 平扫相关性

Adaptive design of an X-ray magnetic circular dichroism spectroscopy experiment with Gaussian process modelling

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npj Computational Materials 2018年第1期4卷 639-646页

作者： tetsuro Ueno Hideitsu Hino Ai Hashimoto Yasuo takeichi Masahiro sawada Kanta Ono Quantum Beam Science Research Directorate National Institutes for Quantum and Radiological Science and Technology1-1-1 KotoSayoHyogo 679-5148Japan Institute of Materials Structure Science High Energy Accelerator Research Organization1-1 OhoTsukubaIbaraki 305-0801Japan Elements Strategy Initiative Center for Magnetic Materials Research Center for Magnetic and Spintronic MaterialsNational Institute for Materials Science1-2-1 SengenTsukubaIbaraki 305-0047Japan Department of Computer Science University of Tsukuba1-1-1 TennodaiTsukubaIbaraki 305-8573Japan Hiroshima Synchrotron Radiation Center Hiroshima University2-313 KagamiyamaHigashihiroshimaHiroshima 739-0046Japan Center for Materials Research by Information Integration(CMI2) Research and Services Division of Materials Data and Integrated System(MaDIS)National Institute for Materials Science(NIMS)1-2-1 SengenTsukubaIbaraki 305-0047Japan

Spectroscopy is a widely used experimental technique,and enhancing its efficiency can have a strong impact on materials *** propose an adaptive design for spectroscopy experiments that uses a machine learning technique to improve *** examined X-ray magnetic circular dichroism(XMCD)spectroscopy for the applicability of a machine learning technique to *** XMCD spectrum was predicted by Gaussian process modelling with learning of an experimental spectrum using a limited number of observed data *** sampling of data points with maximum variance of the predicted spectrum successfully reduced the total data points for the evaluation of magnetic moments while providing the required *** present method reduces the time and cost for XMCD spectroscopy and has potential applicability to various spectroscopies.

关键词： spectroscopy circular spectroscopy

Zircon within chromitite requires revision of the tectonic history of the Eoarchean Itsaq Gneiss complex,Greenland

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Geoscience Frontiers 2023年第6期14卷 273-285页

作者： Hikaru sawada tomoaki Morishita Adrien Vezinet Richard Stern Kenichiro tani Ikuya Nishio Kanta takahashi D.Graham Pearson Kristoffer Szilas Department of Earth System Science University of ToyamaToyamaJapan X-Star Japan Agency for Marine-Earth Science and Technology(JAMSTEC)KanagawaJapan Faculty of Geosciences and Civil Engineering Kanazawa UniversityKanazawaJapan Lamont-Doherty Earth Observatory Columbia UniversityPalisadesUSA Volcanoes and Earth’s Interior Research Center JAMSTECKanagawaJapan Department of Earth and Atmospheric Sciences University of AlbertaEdmontonCanada Canadian Centre for Isotopic Microanalysis University of AlbertaEdmontonCanada National Museum of Nature and Science TsukubaJapan Department of Geosciences and Natural Resource Management University of CopenhagenCopenhagenDenmark

the Ujaragssuit Nunat layered(UNL)unit in the Itsaq Gneiss Complex,west Greenland,has been consid-ered to contain one of the oldest chromitites on Earth based on~ca.4.1 Ga Hadean whole rock Pt-Os model ages and ca.3.81 Ga zircon U-Pb age of the surrounding *** study obtained zircon from the chromitite within this unit as well as granitoid sheets that intruded into the UNL ***-situ U-Pb-Hf-O isotope measurements were made on the *** from both the chromitite and the intrusive granitoids show concordant U-Pb ages of ca.2.97-2.95 *** contrast,Hf and 0 isotopic anal-yses indicate that zircons in the chromitites have a different origin from those in the intrusive *** from granitoids yielded th/U ratios higher than 0.2,initial Hf isotope ratios of 0.2805-0.2807(i.e,initial:Hf value of-11 to-5),andδ^(18)O values of mostly 6.0‰-7.0‰,which are typical for felsic igneous rocks in Archean continental *** least altered zircons from a chromitite exhibited initial Hf isotope ratios of 0.28078-0.28084(i.e.,initial:Hf value of-1.1 to-0.4),close the chondritic value at ca.3.0 Ga and the depleted mantle at ca.3.2 *** zircons also haveδ^(18)O values of 4.2‰6.1‰which correspond to typical mantle *** other chromitite zircons yielded th/U ratios lower than 0.1,and Hf and 0 isotopic compositions ranging between the least altered zircons and the intrusive granitoid *** results indicate that the zircons in the chromitites crystallized before or during the 2.97-2.95 Ga granitoid intrusion and most of the zircons were altered by subsequent ***,the present results suggest that zircons in the chromitites originally had depleted Hf iso-topic compositions at ca.3.2-3.0 *** can be explained by two different models of the evolution of the UNL *** is that if the UNL unit was formed at>3.81 Ga as previously thought,with the zircons in the chromitites subsequently being precipitated by ca.3.2-2.95 G

关键词： Archean Itsaq gneiss complex Ultramafic rock Metasomatism

MDM2 SNP309 (rs2279744) and p53 Codon Arg72Pro (rs1042522) SNP in Cervical Carcinogenesis

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Advances in Bioscience and Biotechnology 2014年第7期5卷 617-622页

作者： Osamu Nunobiki Hirohide sawada Masatsugu Ueda Cytopathology and Gynecology Osaka Center for Cancer and Cardiovascular Diseases Prevention Osaka Japan Department of Medical technology Kobe Tokiwa University Hyogo Japan

to investigate the association between polymorphisms (SNP) in the p53 and murine double minute 2 homolog (MDM2) promoter 309 in cervical carcinogenesis. SNP at p53 codon 72 polymorphisms and MDM2 promoter 309 (t/G) together with human papillomavirus (HPV) types were examined in a total of 187 cervical smear samples using real time PCR. 27 cases with HPV types 16 and/or 18 had significantly higher frequency of the tG + GG genotype and G allele than 56 with other types of high-risk HPV (P = 0.0136). 48 cases with HPV types 52 and/or 58 had significantly higher frequency of the tG + GG genotype and G allele than 56 with other types of high-risk HPV (P = 0.001). Our studies have demonstrated that the frequency of G allele in MDM2 promoter 309 increased from LSIL to HSIL and that there was an increased OR for G allele in HSIL cases with high-risk HPV types including 52 and 58. It is known that geographically different oncogenic HPV types 52 and 58 are more prevalent than 16 and 18 in a Japanese population.

关键词： p53 MDM2 Polymorphism HPV Cervical Carcinogenesis

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超精密铣削的三维微加工工艺

国防科技参考 1997年第3期18卷 31-35页

作者： K.sawada t.Kawai 彭莉日本东京电子通讯大学机械及控制工程部日本tANUC公司基础研究实验室

本研究旨在对用于获取有雕刻表面金属工件的超精密微加工工艺进行探讨。研究中使用的是车床型的超精密铣床,由分辨率为1nm的X和Z向运动工作台及分辨率为0.0001度的可定位的C轴组成。作为一种铣削工具,一种改进型的由一颗水晶钻构成的“... 详细信息

本研究旨在对用于获取有雕刻表面金属工件的超精密微加工工艺进行探讨。研究中使用的是车床型的超精密铣床,由分辨率为1nm的X和Z向运动工作台及分辨率为0.0001度的可定位的C轴组成。作为一种铣削工具,一种改进型的由一颗水晶钻构成的“仿球尖铣刀”被放置在X轴的高速气浮轴承之上。这样一来,X轴和C轴的协调运动就可产生三维铣削的效果。为提高表面粗糙度,通过模拟我们研究的刀具边沿和工件表面的接触情况,结果发现,刀具低速进给时切削比较有效。作为三维微加工工艺的一个例子,运用数字仪提供的扫描数据在一个直径为3mm的铜表面上制作一个传统的NOH面罩。经证明,超精密铣床有潜力加工出表面粗糙度为69nm(P—V值)的工件。

关键词：超精密铣削三维微加工工艺超精密加工

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90钇-替伊莫单抗放射免疫法治疗复发/难治B细胞非霍奇金淋巴瘤的早期疗效评估：FDG-PEt/Ct检查最合适的时间点？

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国际医学放射学杂志 2019年第5期 625-626页

作者： K.Kitajima M.Okada t.Kashiwagi K.Yoshihara t.tokugawa A.sawada 赵一婷 Division of Nuclear Medicine and PEt Center Department of Radiology Hyogo College of Medicine

摘要目的寻找FDG-PEt/Ct评估非霍奇金淋巴瘤(NHL)病人放射免疫治疗(RIt)早期治疗反应的最佳时间点。方法共纳入55例病例。所有病人在RIt治疗前1周

关键词：复发/难治非霍奇金淋巴瘤 FDG-PEt/Ct PEt 放射免疫法早期疗效时间点

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结节性硬皮病:结缔组织生长因子表达增高

世界核心医学期刊文摘（皮肤病学分册） 2006年第1期2卷 44-45页

作者： Yamamoto t sawada Y Katayama I Nishioka K 刘艳 Department of Dermatology Tokyo Medical and Dental University School of Medicine 1-5-45 Yushima Bunkyo-ku Tokyo 113-0034 JapanDr

Background: Nodular scleroderma is a fibrosing reaction, presenting well-defined, firm, raised nodules, which resembles keloid. Recent studies suggest that connective tissue growth factor (CtGF) is involved in the fibrotic process, and its expression is increased in many fibrosing diseases. Objective: In this study, we report 3 cases of nodular scleroderma, and the expression of CtGF is also investigated. Methods: three patients who developed nodular scleroderma are described. Expression of CtGF protein and transcripts in nodular scleroderma was examined by immunohistochemistry and in situ hybridization. Results: Patients were 1 female and 2 males, and all cases were associated with diffuse systemic sclerosis. Nodular lesions were found on the chest (2 cases), back (1 case), upper arm (1 case) and nape (1 case). Histol ogy of the nodular lesions showed thickened collagen bundles in the dermis. Resu lts of immunohistochemistry showed that expression of CtGF was detected on the s clerotic fibroblasts in the lesions of nodular scleroderma, while it was not det ected in fibroblasts in normal skin. In situ expression of CtGF transcripts was abundantly detected on the fibroblastic cells in nodular scleroderma. Conclusion : Our data showed increased expression of CtGF in the sclerotic fibroblasts of n odular scleroderma, suggesting that CtGF plays an important role in its pathogenesis.

关键词：硬皮病生长因子结节性纤维母细胞纤维化过程原位杂交法弥漫性皮损组织病理纤维化疾病真皮

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