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Unilateral post-chemotherapy robot-assisted retroperitoneal lymph node dissection in Stage II non-seminomatous germ cell tumor:A tertiary care experience

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Asian Journal of Urology 2023年第4期10卷 440-445页

作者： Dario Franzese Antonio Tufano Alessandro Izzo Raffaele Muscariello Giovanni Grimaldi Giuseppe Quarto Luigi Castaldo Sabrina Rossetti savio domenico pandolfo Sonia Desicato Paola Del Prete Matteo Ferro Sandro Pignata Sisto Perdonà Department of Urology National Cancer InstitutePascale FoundationNaplesItaly Urology Unit Department of Maternal-Child and Urological Sciences“Sapienza”UniversityRomeItaly Department of Neurosciences Science of Reproduction and OdontostomatologyUniversity of Naples Federico IINaplesItaly Scientific Directorate Istituto Nazionale Tumori di NapoliIRCCS“G.Pascale”NaplesItaly Division of Urology European Institute of Oncology(IEO)IRCCSMilanItaly Division of Medical Oncology Department of Uro-Gynaecological OncologyIstituto Nazionale per lo Studio e la Cura dei Tumori“Fondazione G.Pascale”IRCCSNaplesItaly

Objective Post-chemotherapy retroperitoneal lymph node dissection(PC-RPLND)represents an integral component of the management of patients with non-seminomatous germ cell tumor(NSGCT).Modified templates have been proposed to minimize the surgical morbidity of the ***,the implementation of robotic surgery in this setting has been *** report our experience with unilateral post-chemotherapy robot-assisted retroperitoneal lymph node dissection(PC-rRPLND)for clinical Stages IIA and IIB *** A retrospective single institution review was performed including 33 patients undergoing PC-rRPLND for Stages IIA and IIB NSGCTs between January 2015 and February *** orchiectomy,patients were scheduled for chemotherapy with three cycles of *** with a residual tumor of<5 cm and an ipsilateral metastatic disease on pre-and post-chemotherapy CT scans were eligible for a unilateral template in absence of rising tumor *** statistics were provided for demographics,clinical characteristics,intraoperative and postoperative ***,oncological,and functional outcomes were *** Overall,7(21.2%)patients exhibited necrosis or fibrosis;14(42.4%)had mature teratoma;and 12(36.4%)had viable tumor at final *** median lymph node size at surgery was 25(interquartile range[IQR]21-36)*** operative time was 180(IQR 165-215)min and no major postoperative complications were *** ejaculation was preserved in 75.8%of *** follow-up was 26(IQR 19-30)months and a total of three recurrences were *** PC-rRPLND is a reliable and technically reproducible procedure with safe oncological outcomes and acceptable postoperative ejaculatory function in well selected patients with NSGCTs.

关键词： Testis tumor Robot-assisted retroperitoneal lymph node dissection Retroperitoneal lymph node dissection Non-seminomatous germ cell tumor Unilateral dissection Modified template Post-chemotherapy

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A systematic review of robot-assisted partial nephrectomy outcomes for advanced indications:Large tumors(cT2-T3),solitary kidney,completely endophytic,hilar,recurrent,and multiple renal tumors

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Asian Journal of Urology 2023年第4期10卷 390-406页

作者： savio domenico pandolfo Clara Cerrato Zhenjie Wu Antonio Franco Francesco Del Giudice Alessandro Sciarra Paolo Verze Giuseppe Lucarelli Ciro Imbimbo Sisto Perdonà Edward E.Cherullo Francesco Porpiglia Ithaar H.Derweesh Riccardo Autorino Department of Urology Rush University Medical CenterChicagoILUSA Department of Neurosciences Reproductive Sciences and Odontostomatology“Federico II”UniversityNaplesItaly Department of Urology University of VeronaVeronaItaly Department of Urology Changhai HospitalNaval Medical UniversityShanghaiChina European Association of Urology(EAU)Young Academic Urologists(YAU)Renal Cancer Working Group Arnhemthe Netherlands Department of Urology Sant’Andrea HospitalLa Sapienza UniversityRomeItaly Department of Maternal-Infant and Urologic Sciences La Sapienza UniversityPoliclinico Umberto I HospitalRomeItaly Department of Medicine and Surgery Scuola Medica SalernitanaUniversity of SalernoFiscianoItaly Department of Emergency and Organ Transplantation-Urology Andrology and Kidney Transplantation UnitUniversity of BariBariItaly Department Uro-Gynecology IRCCS G.Pascale FoundationNaplesItaly Department of Urology San Luigi Gonzaga HospitalUniversity of TurinOrbassanoItaly Department of Urology University of California San DiegoLa JollaCAUSA

Objective:Robot-assisted partial nephrectomy(RAPN)has become widely used for treatment of renal cell carcinoma and it is expanding in the field of complex renal *** aim of this systematic review was to analyze outcomes of RAPN for completely endophytic renal masses,large tumors(cT2-T3),renal cell carcinoma in solitary kidney,recurrent tumors,completely endophytic and hilar masses,and simultaneous and multiple ***:A comprehensive search in the PubMed,Scopus,Web of Science,and Cochrane Central Register of Controlled Trials databases was performed in December 2022 for English language *** primary endpoint was to evaluate the role of RAPN in the setting of each category of complex renal masses *** secondary endpoint was to evaluate the surgical and functional ***:After screening 1250 records,43 full-text manuscripts were selected,comprising over 8500 *** and thirteen studies reported data for endophytic and hilar renal masses,*** and three studies reported outcomes for cT2-T3 and solitary kidney patients,*** studies focused on redo-RAPN for recurrent *** studies investigated simultaneous bilateral renal masses and five reports focused on multiple tumor excision in ipsilateral ***:Over the past decade,evidence supporting the use of RAPN for the most challenging nephron-sparing surgery indications has continuously *** limitations remain including study design and lack of detailed long-term functional and oncological outcomes,the adoption of RAPN for the included advanced indications is associated with favorable surgical outcomes with good preservation of renal function without compromising the oncological ***,a higher likelihood of complication might be expected when facing extremely challenging ***,none of these indications should be considered per se an exclusion criterion for performing ***,a risk-adapted approach s

关键词： Robot-assisted partial nephrectomy Complex renal mass Solitary kidney Larger tumors(cT2-T3) Endophytic and hilar mass Recurrent tumor Simultaneous and multiple tumor

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Environmental Data Acquisition, Elaboration and Integration： Preliminary Application to a Vulnerable Mountain Landscape and Village （Novalesa, NW Italy）

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Engineering 2018年第5期4卷 635-642页

作者： Massimiliano Lega Marco Casazza Laura Turconi Fabio Luino domenico Tropeano Gabriele savio Sergio Ulgiati Theodore Endreny Department of Engineering Parthenope University of Napoli Naples 80143 Italy Institute for Hydro-Geological Protection Research National Research Council (CNR-IRPI) Turin 10135 Italy Department of Science and Technology Parthenope University of Napoli Naples 80143 Italy Department of Environmental Resources Engineering College of Environmental Science and Forestry State University of New York Syracuse NY 13210 USA

Climate conditions play a crucial role in the survival of mountain communities, whose survival already critically depends on socioeconomic factors. In the case of montane areas that are prone to natural haz-ards, such as alpine slope failure and debris flows, climatic factors exert a major influence that should be considered when creating appropriate sustainable scenarios. In fact, it has been shown that climate change alters the availability of ecosystem services （ES）, thus increasing the risks of declining soil fertility and reduced water availability, as well as the loss of grassland, potential shifts in regulatory services （e.g., protection from natural hazards）, and cultural services. This study offers a preliminary discussion on a case study of a region in the Italian Alps that is experiencing increased extreme precipitation and erosion, and where an isolated and historically resilient community directly depends on a natural resource econ- omy. Preliminary results show that economic factors have influenced past population trends of the Novalesa community in the Piemonte Region in northwest Italy. However, the increasing number of rock fall and debris flow events, which are triggered by meteo-climatic factors, may further influence the livelihood and weflbeing of this community, and of other similar communities around the world, Therefore, environmental monitoring and data analysis will be important means of detecting trends in landscape and climate change and choosing appropriate planning options. Such analysis, in turn, would ensure the survival of about 10% of the global population, and would also represent a possibility for future economic development in critical areas prone to poverty conditions.

关键词： Environmental data elaboration Climate change Mountain community Italy Resilience Socioecological system Hydrogeological risk

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