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Neurorehabilitation using a voluntary driven exoskeletal robot improves trunk function in patients with chronic spinal cord injury: a single-arm study

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Neural Regeneration Research 2022年第2期17卷 427-432页

作者： Hiroki Okawara Syoichi Tashiro Tomonori Sawada Keiko Sugai Kohei Matsubayashi Michiyuki Kawakami satoshi nori Osahiko Tsuji Narihito Nagoshi Morio Matsumoto Masaya Nakamura Department of Orthopaedic Surgery Keio University School of MedicineTokyoJapan Department of Rehabilitation Medicine Keio University School of MedicineTokyoJapan Department of Orthopedic Surgery National Hospital OrganizationMurayama Medical CenterTokyoJapan

Body weight-supported treadmill training with the voluntary driven exoskeleton(VDE-BWSTT) has been shown to improve the gait function of patients with chronic spinal cord injury. However, little is known whether VDE-BWSTT can effectively improve the trunk function of patients with chronic spinal cord injury. In this open-label, single-arm study, nine patients with chronic spinal cord injury at the cervical or thoracic level(six males and three females, aged 37.8 ± 15.6 years, and time since injury 51.1 ± 31.8 months) who underwent outpatient VDE-BWSTT training program at Keio University Hospital, Japan from September 2017 to March 2019 were included. All patients underwent twenty 60-minute gait training sessions using VDE. Trunk muscular strength, i.e., the maximum force against which patient could maintain a sitting posture without any support, was evaluated in four directions: anterior, posterior, and lateral(right and left) after 10 and 20 training sessions. After intervention, lateral muscular strength significantly improved. In addition, a significant positive correlation was detected between the change in lateral trunk muscular strength after 20 training sessions relative to baseline and gait speed. The change in trunk muscular strength after 20 training sessions relative to baseline was greatly correlated with patient age. This suggests that older adult patients with chronic spinal cord injury achieved a greater improvement in trunk muscle strength following VDE-BWSTT. All these findings suggest that VDE-BWSTT can improve the trunk function of patients with chronic spinal cord injury and the effect might be greater in older adult patients. The study was approved by the Keio University of Medicine Ethics Committee(IRB No. 20150355-3) on September 26, 2017.

关键词： body weight-supported treadmill training gait disorders hybrid assistive limb neurologic neurophysiotherapy postural balance precision medicine robot-assisted gait training robotics spinal cord injury trunk

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Inelastic Scattering of ^(32)Mg at 190 MeV/Nucleon from a Thick Proton Target

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Chinese Physics Letters 2012年第10期29卷 28-30页

作者：李阔昂叶沿林 Heiko SCHEIT Pieter DOORNENBAL 武内聡青井考松下昌史竹下英里本林透櫻井博儀庞丹阳 School of Physics and State Key Laboratory of Nuclear Physics and Technology Peking UniversityBeijing 100871 RIKEN Nishina Center WakoSaitama351-0198Japan School of Physics and Nuclear Energy Engineering Beihang UniversityBeijing 100191

The first excited 2^(+)state(885 keV)of ^(32)Mg and its corresponding deformation parameterβ_(2) are studied with proton inelastic scattering at 190 MeV/nucleon using in-beamγtechnology with a thick target.Angular distributions of the inelastic scattering cross sections are analyzed with coupled-channel calculations.The deformation parameterβ_(2)=0.41(3)obtained in this work agrees with the earlier experimental results obtained at lower beam energies.Our work demonstrates that the structure of unstable nuclei can be studied with proton inelastic scattering at high incident energies in the vicinity of 200 MeV/nucleon using thick targets.

关键词： beam excited incident

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