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Fluorescence‑Based Calibration Model for In‑Situ Measurement of Micro‑scaled Lubricant Thickness Distribution at Indentation Interface

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Nanomanufacturing and Metrology 2024年第2期7卷 76-88页

作者： Motoya yoshikawa Saeko Fujii Shotaro Kadoya Tatsuya Sugihara Masaki Michihata satoru Takahashi Department of Precision Engineering The University of TokyoHongo 7‑3‑1BunkyoTokyo 113‑8656Japan Department of Mechanical Engineering Osaka UniversityYamadaoka 2‑1SuitaOsaka 565‑0871Japan

This study proposes a model for the measurement of microscale liquid film thickness distribution using fluorescence *** interfacial conditions between the tool and the workpiece in mechanical machining are important for understanding these phenomena and *** this study,indentation tests with transparent tools were used to observe interfaces;however,it was challenging to obtain the signal from a thin fluorescent liquid film on smooth and steeply inclined ***,fluorescence-based measurement,such as laser-induced fluorescence,was *** measure the absolute thickness of the thin fluorescent film,calibration of the measurement system is ***,a theoretical model was proposed considering the multiple reflections of excitation light and fluorescence at the inclined surface between the indenter and *** measuring the profile of the surface topography of the indented workpiece and comparing the results with those measured by a surface profiler,the validity of the proposed calibration method and the performance of this measurement system were *** measured surface profiles,including scratches of 2–4μm,were in good agreement,demonstrating the validity of the proposed method.

关键词： Laser-induced fluorescence(LIF) Thickness distribution In-situ measurement Lubricant Mechanical machining

Motion reconstruction of the small carry-on impactor aboard Hayabusa2

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Astrodynamics 2020年第4期4卷 289-308页

作者： Takanao Saiki Yuya Mimasu Yuto Takei Manabu Yamada Hirotaka Sawada K azunori Ogawa Naoko Ogawa Hiroshi Takeuchi Akira Miura Yuri Shimaki Koji Wada Rie Honda Yasuhiro Yokota Kei Shirai Naruhisa Sano Hirohito Ohtsuka Go Ono Kent yoshikawa Shota Kikuchi Chikako Hirose Yukio Yamamoto Takahiro Iwata Masahiko Arakawa Seiji Sugita Satoshi Tanaka Fuyuto Terui Makoto yoshikawa satoru Nakazawa Sei-ichiro Watanabe Yuichi Tsuda Japan Aerospace Exploration Agency Sagamihara 252-5210Japan Chiba Institute of Technology Narashino 275-0016Japan Kobe University K obe 657-8501Japan The Graduate University for Aduanced Studies Sagamihara 252-5210Japan Kochi University Kochi 780-8520Japan IHI Aerospace Co. LtdTomioka 370-2398Japan The University of Tokyo Tokyo 113-0033Japan Nagoya University Nagoya 464-8601Japan

Subsurface exploration is one of the most ambitious scientific objectives of the Hayabusa2 mission.A small device called small carry-on impactor(SCI)was developed to create an artificial crater on the surface of asteroid *** enables us to sample subsurface materials,which will provide a window to the *** physical properties of the resulting crater are also useful for understanding the internal structure of *** understanding of the crater and ejecta properties,including the depth of excavation of subsurface materials,requires accurate information on impact *** particular,the impact angle is a critical factor because it greatly influences the size and shape of the *** April 5,2019,the Hayabusa2 spacecraft deployed the SCI at 500 m of altitude above the asteroid *** SCI gradually reduced its altitude,and it shot a 2 kg copper projectile into the asteroid 40 min after *** the position of the released SCI is essential for determining the impact *** study describes the motion reconstruction of the SCI based on the actual operation *** results indicate that the SCI was released with high accuracy.

关键词： small body exploration Hayabusa2 kinetic impact artificial crater motion reconstruction

Hayabusa2’s station-keeping operation in the proximity of the asteroid Ryugu

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Astrodynamics 2020年第4期4卷 349-375页

作者： Yuto Takei Takanao Saiki Yukio Yamamoto Yuya Mimasu Hiroshi Takeuchi Hitoshi Ikeda Naoko Ogawa Fuyuto Terui Go Ono Kent yoshikawa Tadateru Takahashi Hirotaka Sawada Chikako Hirose Shota Kikuchi Atsushi Fuji Takahiro Iwata satoru Nakazawa Masahiko Hayakawa Ryudo Tsukizaki Satoshi Tanaka Masanori Matsushita Osamu Mori Daiki Koda Takanobu Shimada Masanobu Ozaki Masanao Abe Satoshi Hosoda Tatsuaki Okada Hajime Yano Takaaki Kato Seiji Yasuda Kota Matsushima Tetsuya Masuda Makoto yoshikawa Yuichi Tsuda Japan Aerospace Exploration Agency Sagarmihara 252-5210Japan The Graduate University for Advanced Studies Sagarmihara 252-5210Japan NEC Aerospace Systems LtdFruchu 183-8502Japan NEC Corporation Puchu 183-8501Japan

The Japanese interplanetary probe Hayabusa2 was launched on December 3,2014 and the probe arrived at the vicinity of asteroid 162173 Ryugu on June 27,*** its 1.4 years of asteroid proximity phase,the probe successfully accomplished numbers of record-breaking achievements including two touchdowns and one artificial cratering experiment,which are highly expected to have secured surface and subsurface samples from the asteroid inside its sample container for the first time in *** Hayabusa2 spacecraft was designed not to orbit but to hover above the asteroid along the sub Earth *** orbital and geometrical configuration allows the spacecraft to utilize its high-gain antennas for telecommunication with the ground station on Earth while pointing its scientific observation and navigation sensors at the *** paper focuses on the regular station-keeping operation of Hayabusa2,which is called“home position”(HP)-keeping ***,together with the spacecraft design,an operation scheme called HP navigation(HPNAV),which includes a daily trajectory control and scientific observations as regular activities,is *** the description on the guidance,navigation,and control design as well as the framework of optical and radiometric navigation,the results of the HP-keeping operation including trajectory estimation and delta-V planning during the entire asteroid proximity phase are summarized and evaluated as a first ***,this paper states that the *** operation in the framework of HPNAV had succeeded without critical incidents,and the number of trajectory control delta-V was planned fficiently throughout the period.

关键词： small body mission station-keeping guidance,navigation,and control(GNC) optical and radiometric navigation

Advantageous tactics with certain probiotics for the treatment of graft-versus-host-disease after hematopoietic stem cell transplantation

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World Journal of Hematology 2023年第2期10卷 15-24页

作者： Sayuri yoshikawa Kurumi Taniguchi Haruka Sawamura Yuka Ikeda Ai Tsuji satoru Matsuda Food Science and Nutrition Nara Women's UniversityNara 630-8506Japan

Hematopoietic stem cell transplantation(HSCT)becomes a standard form of cellular therapy for patients with malignant *** is the first-choice of immunotherapy,although HSCT can be associated with many complications such as graft-versus-host disease(GVHD)which is a major cause of morbidity and mortality after allogeneic *** has been shown that certain gut microbiota could exert protective and/or regenerative immunomodulatory effects by the production of short-chain fatty acids(SCFAs)such as butyrate in the experimental models of GVHD after allogeneic *** of gut commensal bacteria which can produce SCFAs may worsen dysbiosis,increasing the risk of *** of G-protein coupled receptors such as GPR41 seems to be upre-gulated in the presence of commensal bacteria,which might be associated with the biology of regulatory T cells(Tregs).Treg cells are a suppressive subset of CD4 positive T lymphocytes implicated in the prevention of GVHD after allogeneic ***,we discuss the current findings of the relationship between the modification of gut microbiota and the GVHD-related immunity,which suggested that tactics with certain probiotics for the beneficial symbiosis in gut-immune axis might lead to the elevation of safety in the allogeneic HSCT.

关键词： Gut microbiota Hematopoietic stem cell Reactive oxygen species Allogeneic hematopoietic stem cell transplantation Graft vs host disease Gut-immune axis©The Author(s)2023.Published by Baishideng Publishing Group Inc.All rights reserved.