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Open Journal of Civil Engineering 2012年第1期2卷 1-9页

作者： Maryoko Hadi satoru murakami Kohei Komatsu Laboratory of Structural Function Kyoto University Kyoto Japan

The alternative types of composite structure made of wood and cement based building materials needs to meet with the high demand for earthquake-resistant houses in Indonesia. In order to understand the mechanism of earthquake resisting performance of shear wall, it is necessary to investigate not only elastic behavior of shear walls but also non-linear one. In this study, series of full-scale experiments on timber frame shear walls composed of Akasia wood (Acacia mangium) sheathed by Fiber Cement Board (FCB) were carried out. For predicting skeleton curve, a series of theoretical equations was derived, which cannot only solve arbitrary nail pattern shear wall but also nonlinear behavior after yielding. Further, for describing hysteresis loops of shear walls, so-called Normalized Cyclic Loop (NCL) model was adopted. By combining two theoretical approaches, weintended to predict whole cyclic shear wall behaviors tested. Good agreements were obtained from comparison between experiment and prediction. The information obtain by this study will be useful for practical engineers or structural designers to design the high performance earthquake resisting timber houses.

关键词： Earthquake-Resistant House Shear Wall Akasia Wood FCB

Dynamic and Static Behaviors of Shear Wall with Openings Composed of LVL and Fiber Cement Board Sheathing

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Open Journal of Civil Engineering 2012年第3期2卷 147-159页

作者： Maryoko Hadi satoru murakami Kohei Komatsu Laboratory of Structural Function RISH KyotoUniversity Kyoto Japan

The shear wall with and without openings that served as a structural element or/and partition wall was utilized in a low-cost housing for the low-income people in Indonesia. The houses,however,should be withstoodfrom earthquake inertial force, so there must be no casualties when disaster struck. The alternative types of composite structure made of wood and cement based building materials needed to meet with the high demand for earthquake-resistant houses in Indonesia. In order to understand the mechanism of earthquake resisting performance of shear wall, we needs to investigate behavior of shear wallsnot only for cyclic static but alsofor dynamic loading. In this study, theseries of full-scale experiment on timber frame shear walls with and without openings,compose of Laminated Veneer Lumber (LVL) engineered wood (Paraserianthes Falcatariaand Hevea Brasiliensis) and sheathed by Fiber Cement Board (FCB), was carried *** analyzing testing result using theoretical approaches, we intended to predict static initial stiffness and yielding strength as well as basic dynamic properties shear walls. For static behavior, good agreements were obtain from comparison between experiment and theoretical prediction based on mechanical model. While, for dynamic behavior, agreement was not sufficient due tothe effect of bending and rocking of actual test specimens. The information obtain by this study will be useful for practical engineers or structural designers to design the high performance earthquake resisting timber houses with a low construction cost.

关键词： Earthquake-Resistant Shear Wall with Opening LVL FCB

Prediction of Reinforcement Effect by Screw on Triangular Embedment Perpendicular to the Grain with Variation of Screw Locations

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Open Journal of Civil Engineering 2012年第3期2卷 167-173页

作者： satoru murakami Akihisa Kitamori Kiho Jung Wen-Shao Chang Kohei Komatsu RISH Kyoto University Kyoto Japan

In this study, the reinforcement by screws for the wood perpendicular to the grain subjected to a rotational moment has been studied. For the estimation of rotational stiffness and yield moment, the reinforcement effect by the screws which varies depending on their position under the bearing plate was evaluated by taking the internal displacement distribution of the wood into account. The Finite Element Analysis (FEA) was used to investigate the internal displacement distribution of the wood. Then an appropriate function was found out to meet well with various internal displacement distributions under the bearing plate. The equations, which can estimate rotational stiffness and yield moment of the bearing performance of the wood reinforced by screws, were derived from the shear resistance mechanism between the screw and wood by considering their relative displacement distribution. Then rotational tests were carried out with the wood reinforced by the screws, setting screw thread at the various positions. Agreements between prediction and experimental results were very well. It was found that the screw reinforcement was effective, provided screw length should be longer for the wood height.

关键词： Screw Reinforce FEA Rotational Performance Timber Structure

Evaluation of Screw Reinforcement on Bearing Performance of Wood Depending on Screw Position

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Open Journal of Civil Engineering 2012年第3期2卷 160-166页

作者： satoru murakami Akihisa Kitamori Kiho Jung Ivon B. Hassel Kohei Komatsu RISH Kyoto University Kyoto Japan

In this study, the reinforcement of wood by screws for partial compression perpendicular to the grain was studied. For the estimation of stiffness and strength, the reinforcement effect of screws depending on their position under the loading plate was evaluated by taking into account the internal displacement distribution of the wood. The finite element analysis (FEA) was used to investigate the internal displacement distribution of the wood. Then an approximate function that can be applied to various internal displacement distributions under loading plate was proposed. From the shear resistance mechanism between the screw and wood by taking their relative displacement distribution into consideration, the equations to estimate the initial stiffness and yield strength of the bearing performance of the wood reinforced by screws were derived. Then partial compression test was carried out for wood reinforced by screws with setting screw thread at various positions. The values obtained by the equations corresponded with the tendency of the experimental results. It was found that the screw reinforcement is more effective when its thread is positioned as much as distant from the contact surface.

关键词： Screw Reinforcement FEM Partial Compression Bearing

Z-shaped incision without epithelial resection in pterygium surgery

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International Journal of Ophthalmology(English edition) 2024年第7期17卷 1262-1266页

作者： satoru Kase Shinki Chin Susumu Ishida Department of Ophthalmology Faculty of Medicine and Graduate School of MedicineHokkaido UniversitySapporo 060-8638Japan

AIM:To introduce a novel surgical technique using a Z-shaped incision without epithelial resection in ophthalmic ***:This was a prospective *** pterygium surgery,all proliferative tissues were separated from the cornea and conjunctiva without resection of the *** unaffected conjunctiva was incised in a *** upper(or lower)conjunctival flap was sutured to the lower(or upper)normal conjunctiva on the limbal sclera,while the proliferative tissue was sutured to the upper conjunctiva(or lower)near the ***:Ten patients with pterygia were eligible for this *** patients with primary pterygia and 2 with recurrent pterygia were *** age of patients at surgery ranged from 47 to 90y(average:71.9y).Five patients each showed right and left-sided *** postoperative follow-up periods were from 8 to 78mo(average:25.0mo).The surgery was successfully conducted and wounds were favorably reconstructed in all *** proliferative tissues sutured to the normal conjunctiva showed palor and attenuated neovessles,and never showed re-growth after *** patients did not show *** pterygium was noted in 1 patient,but additional treatments were not ***:The procedure involves the reconstruction of pterygial tissue and normal conjunctiva using a Z-shaped *** scleral limbal wound can be covered with nonaffected conjunctiva without any excision of conjunctival epithelia in patients with primary or recurrent pterygia.

关键词： pterygium surgery Z-shape non-resection

Chemical reaction in a liquid–liquid phase‐separated multiple droplet:Synchronization of color change dynamics with droplet movement

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Droplet 2024年第1期3卷 103-112页

作者： Kenta Goto Kyoka Nakanishi Fumito Tani satoru Tokuda Department of Chemistry Graduate School of SciencesInstitute for Materials Chemistry and Engineering(IMCE)Kyushu UniversityFukuokaJapan Research Institute for Information Technology Kyushu UniversityKasugaJapan Mathematics for Advanced Materials-Open Innovation Laboratory AISTc/o Advanced Institute for Materials ResearchTohoku UniversitySendaiJapan

Liquid–liquid phase separation in a biotic cell system organizes complicated biochemical reactions and functions by forming membraneless compartments that allow a substrate to move across the phase *** the other hand,liquid–liquid phase separation in an abiotic system gives rise to an emulsion and/or multiple droplets that hardly undergo chemical *** have developed a method for the formation of phase‐separated multiple droplet in a ternary mixture with a 3D‐printed microchannel and demonstrated the occurrence of the iron(III)thiocyanate ligand exchange reaction in the multiple *** reaction proceeded differently in the outer‐and the inner‐droplet phases,giving a different iron(III)complex that was identified on the basis of its color ***,the color change was dynamic,enabling visualization of the interphase mass *** the same time,the color change dynamics synchronized with the multiple‐droplet movement.

关键词： liquid phase separated

Fluorescence‑Based Calibration Model for In‑Situ Measurement of Micro‑scaled Lubricant Thickness Distribution at Indentation Interface

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Nanomanufacturing and Metrology 2024年第2期7卷 76-88页

作者： Motoya Yoshikawa Saeko Fujii Shotaro Kadoya Tatsuya Sugihara Masaki Michihata satoru Takahashi Department of Precision Engineering The University of TokyoHongo 7‑3‑1BunkyoTokyo 113‑8656Japan Department of Mechanical Engineering Osaka UniversityYamadaoka 2‑1SuitaOsaka 565‑0871Japan

This study proposes a model for the measurement of microscale liquid film thickness distribution using fluorescence *** interfacial conditions between the tool and the workpiece in mechanical machining are important for understanding these phenomena and *** this study,indentation tests with transparent tools were used to observe interfaces;however,it was challenging to obtain the signal from a thin fluorescent liquid film on smooth and steeply inclined ***,fluorescence-based measurement,such as laser-induced fluorescence,was *** measure the absolute thickness of the thin fluorescent film,calibration of the measurement system is ***,a theoretical model was proposed considering the multiple reflections of excitation light and fluorescence at the inclined surface between the indenter and *** measuring the profile of the surface topography of the indented workpiece and comparing the results with those measured by a surface profiler,the validity of the proposed calibration method and the performance of this measurement system were *** measured surface profiles,including scratches of 2–4μm,were in good agreement,demonstrating the validity of the proposed method.

关键词： Laser-induced fluorescence(LIF) Thickness distribution In-situ measurement Lubricant Mechanical machining

Improvement of histone deacetylase inhibitor efficacy by SN38 through TWIST1 suppression in synovial sarcoma

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Cancer Innovation 2024年第2期3卷 80-95页

作者： satoru Sasagawa Jun Kumai Toru Wakamatsu Yoshihiro Yui Molecular Biology Laboratory Research InstituteNozaki Tokushukai HospitalDaitoOsakaJapan Sarcoma Treatment Laboratory Research InstituteNozaki Tokushukai HospitalDaitoOsakaJapan Department of Musculoskeletal Oncology Service Osaka International Cancer InstituteOsakaJapan

Background:Synovial sarcoma(SS)is an SS18-SSX fusion gene-driven soft tissue sarcoma with mesenchymal characteristics,associated with a poor prognosis due to frequent metastasis to a distant organ,such as the *** deacetylase(HDAC)inhibitors(HDACis)are arising as potent molecular targeted drugs,as HDACi treatment disrupts the SS oncoprotein complex,which includes HDACs,in addition to general HDACi *** provide further molecular evidence for the advantages of HDACi treatment and its limitations due to drug resistance induced by the microenvironment in SS cells,we examined cellular responses to HDACi treatment in combination with two-dimensional(2D)and 3D culture ***:Using several SS cell lines,biochemical and cell biological assays were performed with romidepsin,an HDAC1/2 selective ***38 was concomitantly used as an ameliorant drug with romidepsin ***,apoptosis induction,and MHC class I polypeptide-related sequence A/B(MICA/B)induction were monitored to evaluate the drug *** addition to the conventional 2D culture condition,spheroid culture was adopted to evaluate the influence of cell-mass microenvironment on ***:By monitoring the cellular behavior with romidepsin and/or SN38 in SS cells,we observed that responsiveness is diverse in each cell *** the apoptotic inducible cells,co-treatment with SN38 enhanced cell *** nonapoptotic inducible cells,cytostasis and MICA/B induction were observed,and SN38 improved MICA/B induction *** a novel efficacy of SN38,we revealed TWIST1 suppression in SS *** the spheroid(3D)condition,romidepsin efficacy was severely restricted in TWIST1-positive *** demonstrated that TWIST1 downregulation restored romidepsin efficacy even in spheroid form,and concomitant SN38 treatment along with romidepsin reproduced the ***:The current study demonstrated the benefits and concerns of using HDACi for SS treatment in 2D and

关键词： HDAC inhibitor MICA/B SN38 spheroid synovial sarcoma TWIST1

Construction and performance test of charged particle detector array for MATE

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Nuclear Science and Techniques 2024年第8期35卷 92-100页

作者： Xiao‑Bin Li Long‑Hui Ru Zhi‑Chao Zhang Bing‑Feng Lv Ning‑Tao Zhang Jin‑Long Zhang Chen‑Gui Lu Bing‑Shui Gao Jun‑Bing Ma Fu‑Shuai Shi satoru Terashima Xiao‑Dong Xu Zhen Bai Shi‑Wei Xu Yan‑Yun Yang Hooi‑Jin Ong Xiao‑Dong Tang Institute of Modern Physics(IMP) Chinese Academy of SciencesLanzhou 730000China School of Nuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China Research Center for Nuclear Physics Osaka UniversityIbarakiOsaka 567‑0047Japan RIKEN Nishina Center WakoSaitama 351‑0198Japan Joint Department for Nuclear Physics Lanzhou University and Institute of Modern PhysicsChinese Academy of SciencesLanzhou 730000China

A charged particle array named MATE-PA,which serves as an auxiliary detector system for a Multi-purpose Active-target Time projection chamber used in nuclear astrophysical and exotic beam Experiments(MATE),was *** array comprised of 20 single-sided strip-silicon detectors covering approximately 10%of the solid *** detectors facilitated the detection of reaction-induced charged particles that penetrate the active volume of the *** performance of MATE-PA has been experimentally studied using an alpha source and a 36-MeV 14 N beam injected into the MATE chamber on the radioactive ion beam line in Lanzhou(RIBLL).The chamber was filled with a gas mixture of 95%4 He and 5%CO_(2) at a pressure of 500 *** results indicated good separation of light-charged particles using the forward double-layer silicon detectors of *** energy resolution of the Si detectors was deduced to be approximately 1%(σ)for an energy loss of approximately 10 MeV caused by theα*** inclusion of MATE-PA improves particle identification and increases the dynamic range of the kinetic energy of charged particles,particularly that of theαparticles,up to approximately 15 MeV.

关键词： Silicon detector array Active target Time projection chamber

In-Process Diameter Measurement Technique for Micro-Optical Fiber with Standing Wave Illumination

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Nanomanufacturing and Metrology 2021年第1期4卷 28-36页

作者： Masaki Michihata Zhao Zheng Daiki Funaiwa Sojiro murakami Shotaro Kadoya satoru Takahashi Department of Precision Engineering The University of Tokyo7-3-1 HongoBunkyoTokyo 113-8654Japan Research Center for Advanced Science and Technology The University of Tokyo4-6-1 KomabaMeguroTokyo 153-8904Japan

In this paper,we propose an in-process measurement method of the diameter of micro-optical fiber such as a tapered optical *** proposed technique is based on analyzing optically scattered light generated by standing wave *** proposed method is significant in that it requires an only limited measurement range and does not require a high dynamic range *** properties are suitable for in-process *** experiment verified that the proposed method could measure a fiber diameter as stable as±0.01μm under an air turbulence *** a result of comparing the measured diameter distribution with those by scanning electron microscopy,it was confirmed that the proposed method has a measurement accuracy better than several hundred nanometers.

关键词： Micro-fiber In-process measurement Mi scattering theory Standing wave Diameter