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中华高血压杂志 2018年第4期26卷 368-368页

作者：刘莉叶鹏 Zhu W Wang H Wei J sartor gc Bao MM Pierce CT Wahlestedt CR Dykxhoorn DM Dong C

滥用可卡因可增加心血管病死亡和发病风险,然而,其中潜在的分子机制仍然未知。通过可卡因滥用小鼠模型,Zhu等发现重复注射可卡因可导致小鼠血压升高和主动脉僵硬度增加（主动脉中活性氧水平同时升高）,这种现象类似于人类高血压中观察... 详细信息

滥用可卡因可增加心血管病死亡和发病风险,然而,其中潜在的分子机制仍然未知。通过可卡因滥用小鼠模型,Zhu等发现重复注射可卡因可导致小鼠血压升高和主动脉僵硬度增加（主动脉中活性氧水平同时升高）,这种现象类似于人类高血压中观察到的现象。

关键词：主动脉僵硬度可卡因滥用升高血压活性氧果酸酶通路小鼠模型发病风险

Analysis of Citizen Participation in Urban Planning of Comala,Colima,Mexico-A Secondary Publication

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Journal of World Architecture 2024年第1期8卷 63-75页

作者： Amallinaly gcárdenas Aguilar Peter Chung Alonso Alicia Cuevas Muñiz Dora Correa Fuentes Ignacio Barajas Avalos National Technological Institute of Mexico Mexico CityMexico University of Colima Colima 28040Mexico

The objective of this study was to determine the degree of citizen participation in urban planning processes in the municipality of Comala,Colima,Mexico to have a broader vision of the citizens and the environment in which they *** instrument was designed specifically to perform this study and the instrument was validated by calculating Cronbach’s *** results showed that citizens were highly involved in issues concerning their urban environment,and the main problems of the public spaces were also identified.

关键词： Citizen participation Planning Urban development program

In vitro and in silico approach for the evaluation of enzyme inhibitory potential of Kadipatta (Murraya koenigii) collected from western Nepal

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Clinical Traditional Medicine and Pharmacology 2024年第4期5卷 44-53页

作者： Suman Prakash Pradhan Ishan Subedi Kapil Adhikari Ashok gc Sujan Prakash Pradhan Mukti Ram Aryal Gopal Prasad Ghimire Bishnu Prasad Pandey Department of Chemical Science and Engineering Kathmandu UniversityPO Box:6250 KavreDhulikhelBagmati Province 45210Nepal Aquatic Ecology Centre Kathmandu UniversityDhulikhel 45210Nepal Department of Environmental Science and Engineering Kathmandu UniversityDhulikhel 45210Nepal Department of Botany Tri-Chandra Multiple CampusKathmandu 44600Nepal Department of Applied Sciences Western Regional CampusPokhara 33700Nepal

Background:Murraya koenigii(L.)Spreng.(Rutaceae)is an evergreen shrub distributed over the sub-tropical to lower temperate climatic zone of Nepal which has been used as spice in culinary practice and traditionally being used to treat bites of poisonous animals,dysentery,skin diseases,vomiting,diarrhea,and ***:The main objective of this study is to study the enzyme inhibition potential of different extracts of *** leaves collected from western ***:Total flavonoid content,total phenolic content,in vitro antioxidant,𝛼α-amylase,lipase,elastase,tyrosinase,and cholinesterase inhibition activities analysis of *** in ethyl acetate,methanol,and water extract were *** addition,high-resolution mass spectrometry-based profiling of flavonoid molecules and their docking analysis were ***:Results revealed the noteworthy radical scavenging activity of ethyl acetate extract against ABTS and *** the analyzed enzymes,*** extracts revealed the highest inhibitory potential towards acetylcholinesterase(AChE)and butyrylcholinesterase(BChE)and only water extract showed the inhibition of *** HPLC-ESI-QTOF-MS analysis revealed the presence of Rutin,Quercetin,Ferulic acid,Hyperoside,Kaempferol-7-O-glucoside,and Morin in ***,in silico docking analysis revealed the significant binding energy of these flavonoid molecules;especially Rutin with ***:The ethyl acetate and methanolic extracts of *** showed paramount flavonoid and phenolic content along with noteworthy potential towardsthe inhibition of neuro-degradative enzymes such as BChE which can be characterized further for pharmacological *** study on the isolation of metabolites and their pharmacological properties from *** is recommended.

关键词： Murraya koenigii 𝛼α-amylase Lipase Elastase Tyrosinase Cholinesrerase

Computational Study on Furnace Process in a Multi-burner Boiler of Pulverized Coal Fired Tangentially at Four Corners

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Journal of Central South University 2000年第3期12卷 152-155页

作者： Zhou, P Mei, C Cong, gc Cent S Univ Technol Dept Appl Phys & Heat Engn Changsha 410083 Peoples R China

Aiming at the optimization of the operation condition, a general numerical method for calculating pulverized coal combustion in a full scale furnace fired tangentially at four corners is adopted. “ k ε ” turbulence model is used for the gas phases and a stochastic approach based on the Lagrangian technique is used for particle phases. Two competing reactions model for the coal devolatilization and PDF (the probability density function) method for the combustion of the gas phases are employed. In the numerical simulations, assuming the air distribution of second port level is of pagoda, waist drum and uniform type. The results show that pagoda type air distribution is advantageous to ignition and smooth combustion of pulverized coal, and suitable to inferior coal combustion in practice. In the present furnace, the igniting distance at 1st and 3rd corner is longer than that at 2nd and 4th corner. The results from numerical calculations are in good agreement with those of observed in practice.

关键词： power station boiler combustion of pulverized coal numerical simulation

Critical Transitions of Microviscosity in Concentrated Polystyrene Solutions Revealed by Excimer Formation of Pyrenyl Probes

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Chinese Chemical Letters 1997年第6期8卷 543-546页

作者： Gao, H Wang, gc He, BL NANKAI UNIV STATE KEY LAB FUNCT POLYMER MAT ADSORPT & SEPARATINST POLYMER CHEMTIANJIN 300071PEOPLES R CHINA

Excimer formation of pyrene and benzyl 4-(1-pyrenyl) butanoate was used to study the microviscosity of polystyrene/toluene solutions over the entire concentration range. Two critical concentrations (C(PS)similar to 0.32, 0.82g/ml) have been observed from the log-log plot of IB/IM vs C-PS. The results are explained in terms of the onset of cohesional interaction and the glass transition of the polymer chains, respectively.

关键词： SCATTERING POLYMER

Construction of energy transfer model of C-phycocyanin and allophycocyanin from Spirulina platensis

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Chinese Science Bulletin 1997年第1期42卷 69-72页

作者： Wang, gc Zhou, BC Zeng, CK Experimental Marine Biology Laboratory Institute of Oceanology Chinese Academy of Sciences Qingdao China

PHYCOBILIPROTEINS. which include phycoerythrin, phycocyanin, phycoerythroeyanin and allophycocyanin, are intensively coloured, highly fluorescent, water soluble chromoproteins. They are composed of at least two dissimilar polypeptides, α and β subunits, in a molar ratio of 1:1. The subunits possess linear tetrapyrrole prosthetic groups covalently linked to the primary structure via cysteine thioether linkages. In blue-green and red algae, phycobiliproteins occur in a supramolecular structure, the phycobilisome, located on the surface of thylakoid to

关键词： Spirulina platensis C-phycocyanin allophycocyanin covalent conjugate energy transfer.

Risk of malignancy in Caroli disease and syndrome: A systematic review

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World Journal of Gastroenterology 2020年第31期26卷 4718-4728页

作者： Rene Fahrner Sandra gc Dennler Daniel Inderbitzin Department of Surgery Bürgerspital SolothurnSolothurn 4500Switzerland Department of Surgery University Hospital DresdenDresden 01307Germany

BACKGROUND Congenital intrahepatic bile duct dilatation without fibrosis is called Caroli disease(CD),and is called Caroli syndrome(CS)when it has fibrotic and cirrhotic liver *** development of intrahepatic carcinoma is described in both conditions,but the reported incidence varies *** risk factors for the malignant transformation were not ***,conservative or surgical treatment is performed depending on the extent of cystic malformation,hepatic dysfunction and structural hepatic changes,but little is known about which treatment should be offered to patients with CD or CS and *** To further investigate the malignant transformation in these *** A systematic review of the current literature until January 2019 was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement.A search using Medline(PubMed)was performed using a combination of Medical Subject Headings terms“caroli disease”,“caroli syndrome”,“tumor”,“malignant”,and“cholangiocarcinoma”.Only human studies published in English were used for this systematic *** following parameters were extracted from each article:year of publication,type of study,number of patients,incidence of malignant tumor,duration of symptoms,age,sex,diagnostics,identification of tumor,surgical therapy,survival and tumor *** Twelve retrospective studies reporting the courses of 561 patients(53%females)were included in this systematic *** a mean age of 41.6 years old(range 23 to 56 years old),patients were younger than other populations undergoing liver *** on the size of the study population the incidence of cholangiocarcinoma varied from 2.7%to 37.5%with an overall incidence of 6.6%.There were only few detailed reports about preoperative diagnostic work-up,but a multimodal work-up including ultrasound of the liver,computed tomography,magnetic resonance imaging and endoscopic retrograd

关键词： Malignancy Caroli disease Caroli syndrome Tumor Cholangiocarcinoma Review

Damping Behaviour and Mechanism of Graphite ParticulateReinforced Metal Matrix Composites

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Journal of Materials Science & Technology 1997年第6期13卷 447-451页

作者： Liu, YC Yang, gc Lu, YL Zhu, ZG Northwestern Polytech Univ State Key Lab Solidificat Proc Xian 710072 Peoples R China Acad Sinica Inst Solid State Phys Internal Frict & Defects Solids Lab Hefei 230031 Peoples R China

The effect of graphite particulate reinforcement on the resultant damping behaviour of ZA27 metal matrix composites (MMCs) has been investigated in an effort to develop a new functional material. The MMCs were processed by a spray atomization and deposition technique. The damping capacity, as well as the relative dynamic modulus, was measured at frequencies of 1 and 4 Hz in the 30 to 200 degrees C temperature range. There exists a transformation point at 55 degrees C in the internal friction and temperature spectrum of the MMCs. It is shown from microstructural analysis that the damping capacity of ZA27 can be significantly improved by the addition of graphites particulates through spray deposition processing. Finally, the operative damping mechanism is discussed in light of the data obtained from characterization of microstructure and damping capacity.

关键词： Graphite Damping Behaviour and Mechanism of Graphite ParticulateReinforced Metal Matrix Composites

Interaction　of　Polyelectrolyte　with　Fluorocarbon　Surfactant　in　Aqueous　Solution

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Chinese Chemical Letters 1996年第10期7卷 951-953页

作者： Wang, YZ Ji, HF Tung, CH Yue, gc ACAD SINICA INST PHOTOG CHEMBEIJING 100101PEOPLES R CHINA JILIN UNIV DEPT ENVIRONM SCICHANGCHUN 130023PEOPLES R CHINA

The variation of the I1/I3 ratio of the fluorescence of pyrene in polystyrene-based quaternary ammonium salt (PA) and sodium carboxymethylamylose (NaCMA) aqueous solutions was measured as a function of sodium perfluorooctanoate (SPFO) concentration. Association of the anionic fluorocarbon surfactant with cationic polyelectrolyte (PA) to form mixed micelles occurred at the surfactant concentrations far below its normal critical concentration, while no interaction between SPFO and anionic polyelectrolyte (NaCMA) was detected. The driving force for the formation of mixed micelles of *** PA is electrostatic interactions.

关键词： POLY-ELECTROLYTE INTERACTIONS FLUORESCENCE PROBE MIXED MICELLES BINDING

Synthesis of some new germasesquioxides by intramolecular catalytic Mannich-type reactions

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Chinese Journal of Chemistry 1997年第6期15卷 548-552页

作者： Zhang, ZB He, DY Chi, gc Chen, RY Nankai Univ Inst Elementoorgan Chem State Key Lab Elementoorgan Chem Tianjin 300071 Peoples R China

A convenient procedure for the preparation of some new germasesquioxides containing phosphonyl groups carried by an intramolecular catalytic Mannich-type reaction is reported.

关键词： germasesquioxide Mannich-type reaction synthesis