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Clinical profile of gastric cancer in Khuzestan, southwest of Iran

World Journal of Gastroenterology 2006年第30期12卷 4832-4835页

作者： Hajiani Eskandar sarmast shoshtari mohammad hossein Masjedizadeh Rahim Hashemi Jalal Azmi Mehrdad Tahereh Rajabi Division of Gastroenterology and Hepatology Department of Internal Medicine Ahwaz Jundishapur University of Medical Sciences Ahwaz Iran Department of Surgery Ahwaz Jundishapur University of Medical Sciences Ahwaz Iran Department of Pathology Ahwaz Jundishapur University of Medical Sciences Ahwaz Iran

AIM： To analyze the characteristics of epidemiological, clinical and survival patterns among patients with carcinoma of the stomach. METHODS： We retrospectively studied the characteristics of 186 gastric adenocarcinoma patients at Ahwaz Jundishapur University Hospitals （AJSUH） from September 1, 1996 to September 1, 2002. All the patients had histopathologically-confirmed malignancy. Demographic variables, family history of gastric cancer （GC）, clinicopathologic characteristics and treatment-related variables were analyzed. Univariate analysis was performed with the log-rank test and multivariate analysis with Cox regression. P 〈 0.05 was considered statistically significant. RESULTS： Male to female ratio was 2.6：1. The mean age was 60.6 years and 14% of the patients were younger than 40 years. Adenocarcinoma, gastric lymphoma, and gastric metastasis were found in 94.5%, 2.3%, and 3% patients, respectively. There was an average of 6-mo delay between the initial symptoms and the diagnosis. Among adenocarcinoma groups, intestinal type was the commonest （55.9%） and the distal third was the most common localization （88.4%）. One hundred and thirty-four patients （72.1%） were males. Thirty-one patients （17%） had a family history of GC. Surgery was performed in 90% of patients （non-curative）. CONCLUSION： The epidemiological features of GC in south Iran mimic those in high-risk areas. There is a higher frequency of GC in young patients at our institution. Patients are detected and treated after a relatively long delay. Most patients present in advanced stages, which favors a poor overall survival, Family history of GC has a significant problem in our area, Studying the etiology of this cancer in south Iran and earlier diagnosis and subsequent better cares are recommended.

关键词： Gastric cancer Epidemiological features Khuzestan Southwest of Iran

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