检索结果-南通市图书馆

Arsenic variability and groundwater age in three water supply wells in southeast New Hampshire

Geoscience Frontiers 2019年第5期10卷 1669-1683页

作者： Joseph P.Levitt James R.Degnan sarah m.flanagan Bryant C.Jurgens U.S.Geological Survey

Three wells in New Hampshire were sampled bimonthly over three years to evaluate the temporal variability of arsenic concentrations and groundwater *** samples had measurable concentrations of arsenic throughout the entire sampling period and concentrations in individual wells had a mean variation of more than 7 μg/*** time series data from this sampling effort showed that arsenic concentrations ranged from a median of 4 mg/L in a glacial aquifer well (SGW-65) to medians of 19 μg/L and 37 μg/L in wells (SGW-93 and KFW-87) screened in the bedrock aquifer,*** high arsenic concentrations were associated with the consistently high pH (median ≥- 8) and low dissolved oxygen (median mg/L) in the bedrock aquifer wells,which is typical of fractured crystalline bedrock aquifers in New *** from the glacial aquifer often has high dissolved oxygen,but in this case was consistently *** pH also is generally acidic in the glacial aquifer but in this case was slightly alkaline (median =7.5).Also,sorption sites may be more abundant in glacial aquifer deposits than in fractured bedrock which may contribute to lower arsenic *** groundwater ages were less than 50 years old in all three wells and correlated with conservative tracer concentrations,such as chloride;however,mean age was not directly correlated with arsenic *** concentrations at KFW-87 did correlate with water levels,in addition,there was a seasonal pattern,which suggests that either the timing of or multiple sampling efforts may be important to define the full range of arsenic concentrations in domestic bedrock *** geochemically reduced conditions and alkaline pHs are common to both bedrock and glacial aquifer wells in this study,groundwater age correlates less strongly with arsenic concentrations than geochemical *** also is evidence of direct hydraulic connection between the glacial and bedrock aquifers,which can influe

关键词： Arsenic variability Geochemical time series Age tracers Groundwater age modeling

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Oryza CLImtools:A genome–environment association resource reveals adaptive roles for heterotrimeric G proteins in the regulation of rice agronomic traits

引用

Plant Communications 2024年第4期5卷 145-165页

作者： Angel Ferrero-Serrano David Chakravorty Kobie J.Kirven sarah m.Assmann Biology Department Pennsylvania State University208 Mueller LaboratoryUniversity ParkPA 16802USA Intercollege Graduate Degree Program in Bioinformatics and Genomics Pennsylvania State University208 Mueller LaboratoryUniversity ParkPA 16802USA

modern crop varieties display a degree of mismatch between their current distributions and the suitability of the local climate for their *** address this issue,we present Oryza CLImtools(https://***/CLImtools/oryza_v1.0/),thefirst resource for pan-genome prediction of climate-associated genetic variants in a crop *** CLImtools consists of interactive web-based databases that enable the user to(1)explore the local environments of traditional rice varieties(landraces)in South-East Asia and(2)investigate the environment by genome associations for 658 Indica and 283 Japonica rice landrace accessions collected from georeferenced local environments and included in the 3K Rice Ge-nomes *** demonstrate the value of these resources by identifying an interplay betweenflowering time and temperature in the local environment that is facilitated by adaptive natural variation in OsHD2 and disrupted by a natural variant in *** quantitative trait locus analysis has suggested the impor-tance of heterotrimeric G proteins in the control of agronomic ***,we analyzed the climate associations of natural variants in the different heterotrimeric G protein *** identified a coordi-nated role of G proteins in adaptation to the prevailing potential evapotranspiration gradient and revealed their regulation of key agronomic traits,including plant height and seed and panicle *** conclude by highlighting the prospect of targeting heterotrimeric G proteins to produce climate-resilient crops.

关键词： Oryza sativa rice G by E adaptation flowering time GWAS OsHD2 OsSOC1 heterotrimeric G pro-tein OsRGA1 d1 OsGS3 OsDEP1 OsGGC2

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Intelligent Solution System for Cloud Security Based on Equity Distribution:model and Algorithms

引用

Computers, materials & Continua 2024年第1期78卷 1461-1479页

作者： sarah mustafa Eljack mahdi Jemmali mohsen Denden mutasim Al Sadig Abdullah m.Algashami Sadok Turki Department of Computer Science and Information College of Science at ZulfiMajmaah UniversityAl-Majmaah11952Saudi Arabia Department of Computer Science College of Computing and InformaticsUniversity of SharjahSharjahUnited Arab Emirates Higher Institute of Computer Science and mathematics University of MonastirMonastir5000Tunisia mars Laboratory University of SousseSousseTunisia Department of Logistic and maintenance UFR MIM at MetzUniversity of LorraineMetzFrance Department of Computer and Information Technologies College of Telecommunicationand Information Riyadh CTITechnical and Vocational Training Corporation TVTCRiyadh12464Saudi Arabia Department of Computer Science Higher Institute of Applied Sciences of SousseSousse UniversitySousse4000Tunisia

In the cloud environment,ensuring a high level of data security is in high *** planning storage optimization is part of the whole security process in the cloud *** enables data security by avoiding the risk of data loss and data *** development of data flow scheduling approaches in the cloud environment taking security parameters into account is *** our work,we propose a data scheduling model for the cloud *** is made up of three parts that together help dispatch user data flow to the appropriate *** first component is the Collector Agent whichmust periodically collect information on the state of the network *** second one is the monitoring agent which must then analyze,classify,and make a decision on the state of the link and finally transmit this information to the *** third one is the scheduler who must consider previous information to transfer user data,including fair distribution and reliable *** should be noted that each part of the proposedmodel requires the development of its *** this article,we are interested in the development of data transfer algorithms,including fairness distribution with the consideration of a stable link *** algorithms are based on the grouping of transmitted files and the iterative *** proposed algorithms showthe performances to obtain an approximate solution to the studied problem which is an NP-hard(Non-Polynomial solution)*** experimental results show that the best algorithm is the half-grouped minimum excluding(HmE),with a percentage of 91.3%,an average deviation of 0.042,and an execution time of 0.001 s.

关键词： Cyber-security cloud computing cloud security algorithms heuristics

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Feasibility,efficacy,and safety of animal-assisted activities with visiting dogs in inpatient pediatric oncology

引用

World Journal of Pediatrics 2024年第9期20卷 915-924页

作者： Katja Steff maximilian Grasemann Kira Ostermann sarah Christina Goretzki Peter-michael Rath Dirk Reinhardt michael m.Schündeln Pediatric Hematology and Oncology Department of Pediatrics IIIUniversity of Duisburg-EssenHufelandstr.5545122EssenGermany Department of Psychology Medical School HamburgHamburgGermany Pediatric Infectiology Department of Pediatrics IUniversity of Duisburg-EssenEssenGermany Institute of medical microbiology University of Duisburg-EssenEssenGermany

Background Childhood cancer entails a heavy burden for patients and their *** advances in overall survival rates have increasingly brought long-term quality of life into ***-assisted activities(AAAs)have long been hypothesized to alleviate the burden on pediatric patients and their peers in the hospital ***,their use in inpatient pediatric oncology has been a sensitive issue mainly due to the fear of infections,resulting in a lack of *** study presents data on the feasibility,safety,and efficacy of AAAs from a single German *** Between 2018 and 2022,60 patients(median age=10.3 years)diagnosed with malignancy and undergoing treatment were visited by an intervention dog(total visits=100).Patients were screened for infections as per hospital policy,with additional microbiological testing performed based on *** dog was screened for human pathogens and *** data and hospitalizations were analyzed from two months prior to the first visit until two months after the last *** of being in the hospital,both with and without planned animal-assisted interventions and pre-and post-intervention state stress,were measured using a validated visual analogue scale(0-10).Results Patients benefited from AAAs,showing increased acceptance of being in the hospital(median:7.25 vs.4.50,Pmedian state stress ratings one hour after the visit compared to one hour before the visit(1.00 vs.4.25,Pmber of infections or unplanned hospitalizations,and no zoonoses were *** microbial screening tests of the dog were *** AAAs with visiting dogs in inpatient pediatric oncology are feasible and *** they hold promise for enhancing patients’well-being,further prospective studies are needed.

关键词： Animal-assisted activities Animal-assisted interventions Animal-assisted therapy Feasibility Infection control Inpatient pediatric oncology Safety Stress response Therapy dog Visiting dog

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Design and synthesis of synthetic promoters for consistency of gene expression across growth phases and scale in ***

引用

Synthetic and Systems Biotechnology 2024年第2期9卷 330-339页

作者： Kristin V.Presnell Omar melhem sarah m.Coleman Nicholas J.morse Hal S.Alper mcKetta Department of Chemical Engineering The University of Texas at Austin200E Dean Keeton St.Stop C0400AustinTX78712USA Institute for Cellular and molecular Biology The University of Texas at Austin2500 Speedway AvenueAustinTX78712USA

metabolic engineering and synthetic biology endeavors benefit from promoters that perform consistently(or robustly)with respect to cellular growth phase(exponential and stationary)and fermentation scale(microtiter plates,tubes,flasks,and bioreactors).However,nearly all endogenous promoters(especially in Saccharomyces cerevisiae)do not perform in this *** this work,a hybrid promoter engineering strategy is leveraged to create novel synthetic promoters with robustness across these *** a multi-dimensional RNA-seq dataset,promoters with specific phase dependencies were *** enriched with functional transcription factors were identified using mEmE *** motif-containing fragments could impart activity dependence in the opposing ***,we obtain two new promoters with high and consistent expression across both phases by increasing the exponential phase activity of the starting stationary-phase scaffold by 38 and 23-fold ***,we show that these promoters function consistently across various laboratory growth scales over time in a microtiter plate and in ***,this work presents and validates a new strategy for engineering promoters in *** with high levels of expression that are robust to cellular growth phase and the scale of the culture.

关键词： endogenous synthetic stationary

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Discoid meniscus:Treatment considerations and updates

引用

World Journal of Orthopedics 2024年第6期15卷 520-528页

作者： Waleed Albishi Amjad Albaroudi Abdulrahman m Alaseem sarah Aljasser Ibrahim Alshaygy Abdullah Addar Department of Orthopedic Surgery College of MedicineKing Saud UniversityRiyadh 11362Saudi Arabia

A discoid meniscus is a morphological abnormality wherein the meniscus loses its normal‘C’*** most patients are asymptomatic,patients might still present with symptoms such as locking,pain,swelling,or giving *** resonance imaging is usually needed for confirmation of *** on a constellation of factors,including clinical and radiological,different approaches are chosen for the management of discoid *** purpose of this review is to outline the treatment of discoid meniscus,starting from conservative approach,to the different surgical options for this *** Pubmed and Google Scholar databases were used for this *** discussing the treatment of discoid meniscus from 2018 to 2023 were *** there were 369 studies retrieved,and after removal of studies using the exclusion criteria,26 studies were included in this *** such as stability,presence of tear,and morphology can help with surgical *** approaches have been used to treat discoid meniscus,where the choice is tailored for each patient ***,factors that may positively impact patient outcomes include male sex,body mass indexmptom onsetmptomsmeniscectomy with or without repair;however,recently,there has been an increased emphasis on discoid-preserving techniques such as meniscoplasty,meniscopexy,and meniscal allograft transplantation.

关键词： Discoid meniscus Saucerization Partial meniscectomy meniscoplasty meniscopexy meniscal allograft transplantation Arthroscopy Knee

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

In situ apatite and carbonate Lu-Hf and molybdenite Re-Os geochronology for ore deposit research:method validation and example application to Cu-Au mineralisation

引用

Geoscience Frontiers 2024年第5期15卷 339-354页

作者： Alexander Simpson Stijn Glorie martin Hand sarah E.Gilbert Carl Spandler marija Dmitrijeva Greg Swain Angus Nixon Jacob mulder Carsten münker Department of Earth Sciences University of AdelaideSA 5005Australia mineral Exploration Cooperative Research Centre University of AdelaideSA 5005Australia Adelaide microscopy University of AdelaideSA 5005Australia Fortescue Level 287Adelaide TerraceEast PerthWA 6005Australia Institute of Geology und mineralogy University of Köln50674 KölnGermany British Geological Survey NottinghamUK

The development of laser ablation inductively coupled plasma quadrupole tandem mass spectrometry(LA-ICP-Q-mS/mS)opens new opportunities to rapidly date a variety of hydrothermal *** we present in situ Lu-Hf and Re-Os dates for hydrothermal apatite and molybdenite,*** further report the first in situ Lu-Hf dates for bastnäsite,dolomite,and siderite,and assess their potential for constraining ore deposit *** method validation,we report isotope-dilution Lu-Hf dates for apatite reference material Bamble-1(1102±5 ma)and calcite reference material mE-1(1531±7 ma),enabling improved accuracy on matrix-matched calibration for LA-ICP-mS/mS Lu-Hf *** new methods are applied to the Vulcan Iron-Oxide Copper-Gold(IOCG)prospect in the Olympic Cu-Au Province of South *** deposits have been difficult to accurately date,given the general lack of reliable mineral geochronometers that are cogenetic with IOCG *** apatite Lu-Hf dates and molybdenite Re-Os dates demonstrate that mineralisation at Vulcan largely occurred at ca.1.6 Ga,contemporaneous with the world class Olympic Dam *** data also indicates that the Lu-Hf system in apatite is more robust than the U-Pb system for determining the timing of primary apatite formation in an IOCG *** further demonstrate that dolomite can retain Lu-Hf growth ages over an extended time period(>1.5 billion years),providing constraints on the timing of primary ore mineral crystallisation during brecciation and IOCG ***,late Neoproterozoic(ca.589–544 ma)and Carboniferous(ca.334±7 ma)Lu-Hf dates were obtained for texturally late Cubearing carbonate veins,illustrating that the carbonate Lu-Hf method allows direct dating of Cu remobilisation *** has important implications for mineral exploration as the remobilised Cu may have been transferred to younger deposits hosted in Neoproterozoic sedimentary basins overlaying the Olympic IOCG provi

关键词： Reaction-cell ICP-mS In-situ geochronology Lu-Hf Re-Os Iron Oxide Copper Gold metal fluids

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Steroidal scaffold decorations in Solanum alkaloid biosynthesis

引用

molecular Plant 2024年第8期17卷 1236-1254页

作者： Rosalind Lucier mohamed O.Kamileen Yoko Nakamura Sofiia Serediuk Ranjit Barbole Jens Wurlitzer maritta Kunert sarah Heinicke sarah E.O'Connor Prashant D.Sonawane Department of Natural Product Biosynthesis Max Planck Institute for Chemical Ecology07745 JenaGermany Research Group Biosynthesis and NmR Max Planck Institute for Chemical Ecology07745 JenaGermany Biochemical Sciences Division CSIR-National Chemical LaboratoryPune 411008MaharashtraIndia

Steroidal glycoalkaloids(SGAs)are specialized metabolites produced by hundreds of Solanum species,including important vegetable crops such as tomato,potato,and *** it has been known that SGAs play important roles in defense in plants and“anti-nutritional"effects(e.g.,toxicity and bitterness)to humans,many of these molecules have documented anti-cancer,anti-microbial,antiinflammatory,anti-viral,and anti-pyretic *** these,α-solasonine andα-solamargine isolated from black nightshade(Solanum nigrum)are reported to have potent anti-tumor,anti-proliferative,and anti-inflammatory ***,α-solasonine andα-solamargine,along with the core steroidal aglycone solasodine,are the most widespread SGAs produced among the Solanum ***,it is still unknown how plants synthesize these bioactive steroidal *** comparative metabolomictranscriptome-guided approach,biosynthetic logic,combinatorial expression in Nicotiana benthamiana,and functional recombinant enzyme assays,here we report the discovery of 12 enzymes from *** that converts the starting cholesterol precursorto solasodine aglycone,and the downstreamα-solasonine,α-solamargine,and malonyl-solamargine SGA *** further identified six enzymes from cultivated eggplant that catalyze the production ofα-solasonine,α-solamargine,and malonyl-solamargine SGAs from solasodine aglycone via glycosylation and atypical malonylation *** work provides the gene tool box and platform for engineering the production of high-value,steroidal bioactive molecules inheterologoushosts usingsyntheticbiology.

关键词： steroidal glycoalkaloids Solanum biosynthetic pathway α-solamargine malonyl-solamargine specialized metabolites

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Letter to the Editor: Reverse T3;a Reliable Diagnostic Test for Discerning between Euthyroid Sick and Central Hypothyroidism

引用

Open Journal of Endocrine and metabolic Diseases 2024年第2期14卷 73-74页

作者： Udaya m. Kabadi sarah Exley Broadlawns medical Center Des Moines Iowa Faulty of Endocrinology Clinic University of Iowa Iowa City Iowa

Letter to the Editor

关键词： Letter ism Sick

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Assessing bioactivity of environmental water samples filtered using nanomembrane technology and mammalian cell lines

引用

Eco-Environment & Health 2024年第3期3卷 347-354页

作者： sarah E.morgan Lisa A.DeLouise Department of Environmental medicine University of Rochester Medical CenterRochesterNY 14642USA Department of Biomedical Engineering University of RochesterRochesterNY 14627USA Department of Dermatology University of Rochester Medical CenterRochesterNY 14642USA Lake Ontario Center for microplastics and Human Health in a Changing Environment University of Rochester Medical CenterRochesterNY 14642USA

This project reports on the use of a novel nanomembrane filtering technology to isolate and analyze the bioactivity of microplastic(mP)-containing debris from Lake Ontario water *** mPs are a complex mixture of polymers and sorbed chemicals that are persistent and can exhibit a wide range of toxic *** human exposure to mPs is unavoidable,it is necessary to characterize their bioactivity to assess potential health *** work seeks to quantify mP presence in the nearshore waters of Lake Ontario and begin to characterize the bioactivity of the filtrate containing *** utilized silicon nitride(SiN)nanomembrane technology to isolate debris sized between 8 and 20μm from lake water samples collected at various times and *** were identified with Nile red ***-based assays were conducted directly on the filtered debris to test for cell viability,aryl hydrocarbon receptor(AhR)activity,and interleukin 6(IL-6)levels as a measure of proinflammatory *** samples contained *** of the isolated debris impacted cell ***,AhR activity and IL-6 levels varied over ***,no associations were observed between the amount of plastic and *** differences in activity are likely due to variations in the physiochemical properties of debris between *** results highlight the need for increased sampling to fully characterize the bioactivity of mPs in human cells and to elucidate the role that sample physiochemical and spatiotemporal properties play in this activity.

关键词： microplastics SiN nanomembranes Lake Ontario Aryl hydrocarbon receptor(AhR)activity IL-6 levels Bioactivity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：