检索结果-南通市图书馆

Synergistic Mixture of Cyperus esculentus, Phoenix dactylifera and Cocos nucifera Aqueous Extract: Its Liver and k.dney Benefits in Male Albino Rat Model

引用

Journal of Biosciences and Medicines 2023年第10期11卷 63-75页

作者： Tamuno-Boma Odinga Cletus Barizoge Lemii Iyaeneomi Ransome Dak. Christine U. Gabriel-Brisibe sarah k. enebeli Iyingiala Austin-Asomeji Felicia Ucheawaji Edward Department of Biochemistry Faculty of Science Rivers State University Port Harcourt Nigeria Department of Pharmacology and Therapeutics Faculty of Basic Medical Sciences College of Basic Medical Science Rivers State University Port Harcourt Nigeria Department of Medical Biochemistry Faculty of Basic Medical Sciences College of Medical Science Rivers State University Port Harcourt Nigeria Department of Community Medicine Faculty of Clinical Sciences College of Medical Sciences Rivers State University Port Harcourt Nigeria

Back.round: The synergistic mixture of Cyperus esculentus, Phoenix dactylifera and Cocos nucifera (STCD) aqueous extract is a common drink.in Port Harcourt, Nigeria. It is assumed to have various health benefits. However, the synergistic mixture of the content has not been studied scientifically, hence the need to evaluate its effect on the liver and k.dney being part of the body’s metabolic organs. Aim: This study evaluated the synergistic mixture of Cyperus esculentus, Phoenix dactylifera and Cocos nucifera (STCD) aqueous extract in male albino rats. Methods: Acute toxicity LD50 of STCD was carried out, afterwards, fifteen male albino rats were grouped into three groups with 5 rats in each group;Control, 200 mg/k., 400 mg/k. STCD. The rats were administered STCD orally 24 hourly, for 21 days, with feed and water ad libitum. At the end of the experiment, blood samples were collected for biochemical analysis of the liver and k.dney biomark.rs, while the liver and k.dney tissues were harvested for histopathological examination using standard laboratory methods. Descriptive statistics were computed and expressed as Mean ± SD. One-way ANOVA and Turk.ys test was performed. P value ≤0.05 was considered statistically significant. Results: Acute toxicity LD50 of STCD was observed to be ≥2404.2 mg/k. body weight. An increase in the percentage body weight difference of 8.39% and 2.86% was observed for 200 and 400 mg/k. STCD groups. Also, the liver weight was observed to increase in 400 mg/k. (3.92 ± 1.42) in comparison to the control group (3.48 ± 1.61), a decrease in the k.dney weight was observed in all groups administered STCD in comparison to the control group. Administration of STCD at both 200 and 400 mg/k. revealed a decrease in the concentration of the hepatic biomark.rs AST, ALT, ALP, TP, Albumin, Total and conjugated bilirubin. The k.dney biomark.r Urea was observed to decrease in concentration for 200 mg/k. STCD (4.60 ± 1.83) and 400 mg/k. STCD (4.76 ±

关键词： Cyperus esculentus (Tiger nuts) Phoenix dactylifera (Dates) and Cocos nucifera (Coconuts) Liver k.dney Male Rats

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：