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Isolation and Characterization of Cyanobacterial Community Including a Microcystin-Producing Nostoc sp. Strain in the Nile River, Egypt

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Advances in Microbiology 2013年第6期3卷 38-46页

作者： Ranya Amer Rehab Shehawy saraa saad el-dien Marwa Abu Serie Kamel Shaker City for Scientific Research and Technology Applications (SRTACity) New Borg El Arab Alexandria Egypt

The combined use of morphological identification and phylogenetic characterization employing primers that target the 16S rDNA region led to the identification of ten isolates belonging to eight cyanobacterial genera in the Nile River. 16S-23S ITS region was amplified to confirm two isolates to be affiliated to genus Nostoc. Using MALDI-TOF/MS, we detected the production of the hepatotoxic demethylated MC-LR by one isolate that clustered together with the genus Nostoc. Protein phosphatase inhibition assay has confirmed toxicity. Our results add to the rising importance of Nostoc as a hepatotoxin-producing cyanobacterium. Furthermore, our results stress that water municipalities in the studied region need to assess the potential threat of toxic cyanobacteria that may pose to human health and economy.

关键词： Cyanobacteria Nostoc Microcystins Cyanotoxins River

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Effects of 6-Month Weight Loss New Program on Anthropometric Measurements and Biological Profile

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Journal of Pharmacy and Pharmacology 2016年第1期4卷 23-38页

作者： Asmaa F. Hamouda saad el dien A Abou el Noeman Department of biochemistry University of A lexandria Alexandria 21111 Egypt Department of Medical biochemistry University of Tanta Tanta 31511 Egypt

Obesity has become a leading global health problem owing to its strong association with a high incidence of diseases. Obesity is results from the complex interaction of environmental factors that act on a genetic background and led to excess accumulated of body fat. Treatment of obesity includes determination of the degree of obesity, management weight loss programme and maintenance of body weight. To investigate effect 6 months safe weight loss program on anthropometric measurements and biological and metabolic profiles in obese patients. 35 obese patients were enrolled in the present study: 20 female, 15 male. Participants underwent a comprehensive series of biochemical, anthropometrical, physical, and nutritional prior to treatment- at baseline and after the six-month of the obesity treatment program. 6 months weight loss program. Diet plan intervention in small groups. In-person training and individual diet plan intervention. There is significant reduction in weight and high improvement in laboratory parameters. Our data showed that there an improvement in weight loss. These finding may be important for controlling obesity-related co-morbidities. It would appear that moderate weight loss of 8-10 % observed in our study resulted in significant improvements in laboratory parameters

关键词：人体测量减肥生物分布健康问题遗传背景相互作用环境因素生物代谢

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