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Modeling of recrystallization behaviour of AA6XXX aluminum alloy profile during extrusion process

Transactions of Nonferrous Metals Society of China 2024年

作者： Marco Negozio Antonio Segatori Riccardo Pelaccia Barbara Reggiani sara di donato Lorenzo Donati diN Department of Industrial Engineering – University of Bologna University of Parma-Department of Engineering and Architecture Parco Area delle Scienze Hydro Innovation and Technology InterMech-MO.RE – University of Modena and Reggio Emilia diSMI Department of Sciences and Methods for Engineering University of Modena and Reggio Emilia

An innovative approach was introduced for the development of a AA6063 recrystallization model. This method incorporated a regression-based technique for the determination of material constants and introduced novel equations for assessing the grain size evolution. Calibration and validation of this methodology involved a combination of experimentally acquired microstructural data from the extrusion of three different AA6063 profiles and results from the simulation using the Qform Extrusion UK finite element code. The outcomes proved the agreement between experimental findings and numerical prediction of the microstructural evolution. The trend of the grain size variation based on different process parameters has been accurately simulated， both after dynamic and static recrystallization， with an error rate of less than 25% in almost the whole sampling computations.

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Efficacy and tolerability of high and low-volume bowel preparation compared:A real-life single-blinded large-population study

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World Journal of Gastrointestinal Endoscopy 2021年第12期13卷 659-672页

作者： Vincenzo Occhipinti Paola Soriani Francesco Bagolini Valentina Milani Emanuele Rondonotti Maria Laura Annunziata Flaminia Cavallaro sara Vavassori Maurizio Vecchi Luca Pastorelli Gian Eugenio Tontini digestive Endoscopy and Gastroenterology Unit A.Manzoni HospitalASST LeccoLecco 23900Italy Gastroenterology Unit IRCCS Policlinico San DonatoSan Donato Milanese 20097Italy Gastroenterology and digestive Endoscopy Unit Azienda USL ModenaCarpi HospitalCarpi 41012Italy Scientific directorate IRCCS Policlinico San DonatoSan Donato Milanese 20097Italy Gastroenterology Unit Ospedale ValduceComo 22100Italy Gastroenterology and Endoscopy Unit Fondazione IRCCS Ca'Granda Ospedale Maggiore PoliclinicoMilan 20122Italy Gastroenterology and Hepatology Unit ASST Santi Paolo e CarloMilan 20142Italy Department of Pathophysiology and Transplantation University of MilanMilan 20122Italy Department of Biomedical Sciences for Health University of MilanMilan 20122Italy

BACKGROUND Low-volume preparations for colonoscopy have shown similar efficacy compared to high-volume ones in randomized controlled trials(RCT).However,most RCTs do not provide data about clinical outcomes including lesions detection ***,real-life comparisons are *** To compare efficacy(both in terms of adequate bowel preparation and detection of colorectal lesions)and tolerability of a high-volume(HV:4 L polyethylene glycol,PEG)and a low-volume(LV:2 L PEG plus bisacodyl)bowel preparation in a real-life *** Consecutive outpatients referred for colonoscopy were prospectively enrolled between 1 December 2014 and 31 December *** could choose either LV or HV preparation,with a day-before schedule for morning colonoscopies and a split-dose for afternoon *** bowel preparation according to Boston Bowel Preparation Scale(BBPS),clinical outcomes including polyp detection rate(PDR),adenoma detection rate(ADR),advanced adenoma detection rate(AADR),sessile/serrated lesion detection rate(SDR)and cancer detection rate and self-reported tolerability of HV and LV were blindly *** Total 2040 patients were enrolled and 1815(mean age 60.6 years,50.2%men)finally *** was chosen by 52%of patients(50.8%of men,54.9%of women).Split-dose schedule was more common with HV(44.7%vs 38.2%,P=0.005).High-definition scopes were used in 33.4%of patients,without difference in the two groups(P=0.605).HV and LV preparations showed similar adequate bowel preparation rates(89.2%vs 86.6%,P=0.098),also considering the two different schedules(HV split-dose 93.8%vs LV split-dose 93.6%,P=1;HV daybefore 85.5%vs LV day-before 82.3%,P=0.182).Mean global BBPS score was higher for HV preparations(7.1±1.7 vs 6.8±1.6,Pdications for colonoscopy,HV preparation resulted higher in PDR[Odds ratio(OR)1.32,95%CI:1.07-1.63,P=0.011]and ADR(OR 1.29,95%CI 1.02–1.63,P=0.038)and comparable to LV in AADR(OR 1.51

关键词： Bowel preparation volume Polyethylene glycol Bisacodyl Colonoscopy Colonic adenomas Tolerability

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