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Ultrasonic vocalizations in mice: relevance for ethologic and neurodevelopmental disorders studies

Neural Regeneration Research 2021年第6期16卷 1158-1167页

作者： Marika Premoli Maurizio Memo sara anna bonini Department of Molecular and Translational Medicine University of BresciaViale Europa 11BresciaItaly

Mice use ultrasonic vocalizations(USVs)to communicate each other and to convey their emotional *** have been greatly characterized in specific life phases and contexts,such as mother isolation-induced USVs for pups or female-induced USVs for male mice during *** can be acquired by means of specific tools and later analyzed on the base of both quantitative and qualitative ***,different ultrasonic call categories exist and have already been *** understanding of different calls meaning is still missing,and it will represent an essential step forward in the field of *** have long been studied in the ethological context,but recently they emerged as a precious instrument to study pathologies characterized by deficits in communication,in particular neurodevelopmental disorders(NDDs),such as autism spectrum *** review covers the topics of USVs characteristics in mice,contexts for USVs emission and factors that modulate their expression.A particular focus will be devoted to mouse USVs in the context of ***,several NDDs murine models exist and an intense study of USVs is currently in progress,with the aim of both performing an early diagnosis and to find a pharmacological/behavioral intervention to improve patients’quality of life.

关键词： autism spectrum disorders behavioral phenotyping emotional state environmental modulation maternal immune activation mouse models neurodevelopmental disorders social context ultrasonic communication vocalizations classification

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中国文化遗产管理:一项田野研究展望(英文)

中国文化遗产管理:一项田野研究展望(英文)

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北京论坛（2008）文明的和谐与共同繁荣——文明的普遍价值和发展趋向

作者： Luca Zan sara bonini Baraldi Department of Management University of Bologna

Few countries boast a history which is as long and rich as China’s;at the same time,few countries are undergoing economic transformation processes comparable to that which China is currently *** managerial problems accompany the modernization of a huge activity in archeological discovery and research,conservation and promotion,calling for a profound understanding. The subject of the research - carried out in 2005-2008 - is the analysis of change processes regarding managerial aspects in the processes of archeological discoveries,restoration,museum definition and access to cultural heritage in Luoyan City,*** focus is not per se on the archeological discoveries in their historical and artistic meanings,nor on the conservation and restoration in their technical,scientific,and methodological repercussions;nor finally on the evolution of the museology per *** the core of the analysis,the specific perspective is on how these discussions and their evolutions pose managerial and operational problems that present new and specific aspects. The main characteristic of this research,indeed,is the coupling of an aggregate with an in-depth micro *** this regard,nine clinical case histories have been *** case histories investigate managerial problems along the Archaeological chain(from discovery, to protection and conservation,to museum access),aiming at investigating how the changes implied are faced at the single organization *** on a general management perspective, each case history is organized according to a standard ***,some of the elements of interest of the case under investigation are provided,according to the writers.A short characterization of the museum/site/project is also provided,in order to understand the relationship with specific curatorial aspects and issues of organizing,recourses *** assessment of effectiveness is then carried out,drawing on curatorial aspects and - when relevant - access data.

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