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Risk of pacemaker implantation after femur fracture in patients with and without a history syncope: a Danish nationwide registry-based follow-up study

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Journal of Geriatric Cardiology 2022年第9期19卷 712-718页

作者： sara lk clemmensen Kristian Kragholm Bhupendar Tayal Christian Torp-Pedersen Søren Kold Peter Søgaard Sam Riahi Department of Cardiology Aalborg University HospitalAalborgDenmark Unit of Clinical Biostatistics and Epi-demiology Aalborg University HospitalAalborgDenmark Department of Clinical Epidemiology Aalborg University HospitalAalborgDenmark Department of Orthopedics Aalborg University HospitalAalborgDenmark Depart-ment of Clinical Institute Aalborg University HospitalAalborgDenmark

BACKGROUND It has previously been described that fall-associated injuries including fractures are commonly observed among patients with ***,knowledge on the risk of pacemaker implantation after admission due to femur fracture from large population-based epidemiologic data is ***,we investigated the risk of pacemaker implanta-tion following femur fracture in patients with and without a history of previous *** All patients with femur fracture between 2005-2017 were identified using the Danish Nationwide Patient *** these,patients already having a pacemaker were *** outcome was one-year risk of pacemaker implanta-tion and secondary outcome was one-year all-cause *** logistic regression was used to obtain absolute and relative risks of the study endpoint in relation to patients with versus without history of syncope and standardized to the age,sex,selected comorbidity and pharmacotherapy distribution of all *** Of 93,093 patients with femur fracture,5508(5.9%)had a history of syncope within five *** with prior syn-cope were slightly older(84 vs.83 years),more often male(33.6%vs.29.4%),and had more often comorbidities relative to those without history of ***-cause mortality was significantly higher among those with previous history of syncope com-pared to those without previous syncope(29.9%vs.28.6%,P=0.021).The relative mortality risk was 1.05(95%CI:1.01−1.09,P=0.021).A total of 695(0.8%)patients underwent pacemaker implantation within 5 years following femur fracture,and a signific-antly higher proportion of patients with syncope had a pacemaker implanted within one year(1.6%vs.0.7%,P<0.001;relative risk,2.01[95%CI:1.55−2.46]).CONCLUSIONS In patients with femur fracture,a history of syncope was significantly associated with a higher one-year risk of pacemaker implantation.

关键词： patients syncope injuries

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