检索结果-南通市图书馆

The complex role of protocadherin-19 in brain function:a focus on the oxytocin system

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第11期20卷 3211-3212页

作者： sara Mazzoleni Marta Busnelli Silvia Bassani CNR Institute of Neuroscience Vedano al LambroItaly NeuroMi Milan Center for Neuroscience MilanItaly

Mutations in the protocadherin-19(PCDH19)gene(Xq22.1)cause the X-linked syndrome known as developmental and epileptic encephalopathy 9(DEE9,OMIM#300088)(Dibbens et al.,2008).DEE9 is characterized by early-onset clustering epilepsy associated with intellectual disability ranging from mild to profound,autism spectrum disorder,and other neuropsychiatric features including schizophrenia,anxiety,attentiondeficit/hyperactivity,and obsessive or aggressive *** seizures may become less frequent in adolescence,psychiatric comorbidities persist and often worsen with age(Dibbens et al.,2008;Kolc et al.,2020).

关键词： epilepsy function system

Nonlinear aspects of energy dissipation in wood-panel joints sara Casciati

在线全文

学校读者我要写书评

暂无评论

Earthquake Engineering and Engineering Vibration 2007年第4期6卷 259-268页

作者： sara Casciati ASTRA Dept. School of Architecture University of Catania at Siracusa 96100 Siracusa Italy

The joints connecting vertical and horizontal elements are the ＂weak link＂ in structural systems assembled from wood panels. If they are too weak, local failures may occur, resulting in performance that is significantly below expectations. If they are too resistant, the joints may be unable to dissipate energy during vibrations, thus possibly initiating a fast progressive failure. This paper re-processes and re-elaborates the results of shaking table tests previously carried out by the author and other co-workers. The goal is to assess the feasibility of a joint which is able to dissipate energy during vibration, without degrading the connection performance.

关键词： dynamic excitation energy dissipation wood panels joint monitoring system shaking table tests

同方期刊数据库

Patients admitted in the intensive care unit after solid organ or bone marrow transplantation:Retrospective cohort study

在线全文

学校读者我要写书评

暂无评论

World Journal of Transplantation 2025年第1期15卷 95-104页

作者： Ana Vujaklija Brajkovic Iva Kosuta Lucija Batur sara Sundalic Marijana Medic Andro Vujevic Luka Bielen Jaksa Babel Department of Internal Medicine University Hospital Centre ZagrebZagreb 10000Croatia School of Medicine University of ZagrebZagreb 10000Croatia

BACKGROUND Solid organ transplantation(SOT)and hematopoietic stem cell transplantation(HSCT)revolutionized the survival and quality of life of patients with malignant diseases,various immunologic,and metabolic disorders or those associated with a significant impairment in a patient's quality of *** To investigate admission causes and treatment outcomes of patients after SOT or HSCT treated in a medical intensive care unit(ICU).METHODS We conducted a single-center,retrospective epidemiological study in the medical ICU at the University Hospital Centre Zagreb,Croatia covering the period from January 1,2018 to December 31,*** The study included 91 patients with either SOT[28 patients(30.8%)]or HSCT[63 patients(69.2%)].The median age was 56(43.2-64.7)years,and 60.4%of the patients were *** with SOT had more comorbidities than patients after HSCT[χ^(2)(5,n=141)=18.513,P<0.001].Sepsis and septic shock were the most frequent reasons for admission,followed by acute respiratory insufficiency in patients following *** rate significantly differed between SOT and HSCT[χ^(2)(1,n=91)=21.767,P<0.001].ICU survival was 57%in the SOT and 12.7%in the HSCT *** need for mechanical ventilation[χ^(2)(1,n=91)=17.081,P<0.001]and vasopressor therapy[χ^(2)(1,n=91)=36.803,P<0.001]was associated with *** necessity for acute renal replacement therapy did not influence patients'survival[χ^(2)(1,n=91)=0.376,P=0.54].In the subgroup of patients with infection,90%had septic shock,and the majority had positive microbiological samples,mostly Gram-negative *** ICU survival of patients with sepsis/septic shock cumulatively was 15%.The survival of SOT patients with sepsis/shock was 45%.CONCLUSION Patients with SOT or HSCT are frequently admitted to the ICU due to sepsis and septic *** advancements in critical care,the mortality rate of patients with refractory septic shock and multiorgan failure in this patient population is extremely hig

关键词： Liver transplantation Kidney transplantation Hematopoietic stem cell transplantation Critical care Sepsis Septic shock Mortality

Geological Controls and Prospectivity Mapping for Manganese Ore Deposits Using Predictive Modeling Comparison:An Integration of Outcrop and Remote Sensing Data,Sinai Microplate,Egypt

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Earth Science 2023年第2期34卷 588-608页

作者： sara Zamzam Geology Department Faculty of ScienceZagazig UniversityZagazig 44519Egypt

One of the most controversial minerals in their origin and occurrence around the world is manganese *** Abu Zenima area is rated one of the most economically important places where manganese ore deposits(Mn ODs)are located in the southwest Sinai microplate,*** deposits are confined with the Um Bogma Formation(UBF)and the reserves of this region are relatively *** this study,optical and radar data are used in a new challenge as an attempt to reach the closest controls and setting of Mn ***,Frequency Ratio(FR)and Logistic Regression(LogR)predictive models are applied to integrate different geospatial thematic maps,to predict new potential resource zones for increasing the ranges of mining ***8 OLI,Sentinel-2A Multi Spectral Instrument and Radar(Sentinel-1B)data are combined for mapping Mn ODs locations and their relationship with geological structures and the surrounding *** ratio,Principal and Independent Component Analysis techniques and four classification algorithms were implemented to the optical’VNIR and SWIR ***,the interferometric processing steps for Sentinel-1 data were made for understanding the tectonic features in the *** FR and LogR models are validated during fieldwork with known Mn ODs *** indicate that processed images are capable of differentiation of UBF which broadly distributed in the central and southern parts of the *** ODs possibly formed by thermal events that attributed to paleo-volcanic events before the rift *** high accuracy of LogR model(0.902)suggests that high Mn ODs potential zones are identified within the intersected fault zones near granitic *** integration is recommended for discriminating hydrothermally Mn ODs in other arid geographic regions.

关键词： manganese deposits Abu Zenima Landsat8 oli sentinel data fault zones predictive modeling remote sensing

Automatic characterization of spherical metal powders by microscope image analysis:a parallel computing approach

在线全文

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2023年第11期30卷 2293-2300页

作者： Xiang Li Linyi Cui sara Shonkwiler sara McMains University of California BerkeleyBerkeleyCA94720USA The Hong Kong Polytechnic University Hong KongChina

The microstructural characteristics of spherical metal powders play an important role in determining the quality of mechanical parts manufactured by powder metallurgy *** the individual powder particles from their microscopic images is one of the most convenient and cost-efficient methods for the analysis of powder *** numerous image processing algorithms have been developed for automating the powder particle identification process,they perform less accurately in identifying adjacent particles that are heavily overlapped in their image *** propose an automatic algorithm to robustly and accurately identify spherical powder particles,especially heavily overlapped particles,from their microscope images.A parallel computing framework is designed to further enhance the computational efficiency of the proposed *** characteristics such as particle size distribution and the location of potential satellite particles have been derived from our identification *** accuracy and efficiency of our algorithm are validated by real-world scanning electron microscope images,outperforming other existing methods and achieving both precision and recall above 99%.

关键词： computing image overlapped

A Voronoi diagram approach for detecting defects in 3D printed fiber-reinforced polymers from microscope images

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computational Visual Media 2023年第1期9卷 41-56页

作者： Xiang Li sara McMains University of California Berkeley BerkeleyCalifornia94720USA

Fiber-reinforced polymer(FRP)composites are increasingly popular due to their superior strength to weight *** contrast to significant recent advances in automating the FRP manufacturing process via 3D printing,quality inspection and defect detection remain largely manual and *** this paper,we propose a new approach to automatically detect,from microscope images,one of the major defects in 3D printed FRP parts:fiber-deficient areas(or equivalently,resin-rich areas).From cross-sectional microscope images,we detect the locations and sizes of fibers,construct their Voronoi diagram,and employ-shape theory to determine fiber-deficient *** Voronoi diagram and-shape construction algorithms are specialized to exploit typical characteristics of 3D printed FRP parts,giving significant efficiency *** algorithms robustly handle real-world inputs containing hundreds of thousands of fiber cross-sections,whether in general or non-general position.

关键词： 3D printing(3DP) microscope image processing fiber-reinforced polymer(FRP) Voronoi diagrams -shapes resin-rich areas

Solid-state impedance spectroscopy studies of dielectric properties and relaxation processes in Na_(2)O–V_(2)O_(5)–Nb_(2)O_(5)–P_(2)O_(5) glass

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2024年第1期31卷 186-196页

作者： sara Marijan Luka Pavic Division of Materials Chemistry Ruđer Boskovic InstituteBijenicka 54HR-10000 ZagrebCroatia

Solid-state impedance spectroscopy(SS-IS)was used to investigate the influence of structural modifications resulting from the addition of Nb2O5 on the dielectric properties and relaxation processes in the quaternary mixed glass former(MGF)system 35Na_(2)O–10V_(2)O_(5)–(55-x)P_(2)O_(5)–xNb_(2)O_(5)(x=0–40,mol%).The dielectric parameters,including the dielectric strength and dielectric loss,are determined from the frequency and temperature-dependent complex permittivity data,revealing a significant dependence on the Nb2O5 *** transition from a predominantly phosphate glass network(x<10,region I)to a mixed niobate–phosphate glass net-work(10≤x≤20,region II)leads to an increase in the dielectric parameters,which correlates with the observed trend in the direct-cur-rent(DC)*** the predominantly niobate network(x≥25,region III),the highly polarizable nature of Nb5+ions leads to a fur-ther increase in the dielectric permittivity and dielectric *** is particularly evident in Nb-40 glass-ceramic,which contains Na_(13)Nb_(35)O_(94) crystalline phase with a tungsten bronze structure and exhibits the highest dielectric permittivity of 61.81 and the lowest loss factor of 0.032 at 303 K and 10 *** relaxation studies,analyzed through modulus formalism and complex impedance data,show that DC conductivity and relaxation processes are governed by the same mechanism,attributed to ionic *** contrast to glasses with a single peak in frequency dependence of imaginary part of electrical modulus,M″(ω),Nb-40 glass-ceramic exhibits two distinct contributions with similar relaxation *** high-frequency peak indicates bulk ionic conductivity,while the additional low-fre-quency peak is associated with the grain boundary effect,confirmed by the electrical equivalent circuit(EEC)*** scaling characteristics of permittivity and conductivity spectra,along with the electrical modulus,validate time-temperature superposition and demonstrate a

关键词： phosphate glasses glass-ceramics impedance spectroscopy dielectric properties relaxation processes permittivity scaling conductivity scaling modulus formalism

Snapthrough response of an innovative symmetric bistable composite wing

在线全文

学校读者我要写书评

暂无评论

Acta Mechanica Sinica 2024年第9期40卷 68-82页

作者： sara Hijazi Samir Emam Department of Mechanical Engineering American University of SharjahSharjah PO Box 26666United Arab Emirates

This study presents a numerical investigation into the equilibrium shapes and snapthrough response of an innovative bistable symmetric composite *** proposed design is a compound plate that consists of a symmetric flat platform followed by a winglet that utilizes the modified hybrid bistable symmetric laminate recently developed in the *** hybrid layup of the winglet resolves the issue of losing the bistability of the unsymmetric laminate when attached to another *** approximate analytical model based on the Rayleigh-Ritz method is developed for the compound plate that considers the geometric nonlinearity,the clamping conditions at the wing root,and the compatibility conditions at the *** static equilibrium positions predicted by the model were verified against the ABAQUS finite element(FE)results and an excellent agreement was *** influence of the geometrical and material parameters of the proposed design on the static equilibrium shapes and the snapthrough response was *** following parameters were considered:the length ratio of the flat plate to the bistable winglet,the thickness and location of the bidirectional glass epoxy layers,the load location,and the wing’s taperness and aspect *** parameters were found significant,and their effects were *** novelty of this work is that it presents the equilibrium shapes and the snapthrough response of a bistable laminate as a part of a bigger compliant structure,which mimics the scenario in real-life applications.

关键词： Compound laminate Bistable wing Hybrid symmetric laminates Snapthrough

Drag force on a moving heavy quark with deformed string configuration

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2022年第4期74卷 61-67页

作者： sara Tahery Xurong Chen Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China University of Chinese Academy of Sciences Beijing 100049China Guangdong Provincial Key Laboratory of Nuclear Science Institute of Quantum MatterSouth China Normal UniversityGuangzhou 510006China

To study drag force on a moving heavy quark through a plasma,we use a deformed AdS spacetime,in which deformation parameter c describes non-conformality in AdS/*** this case,the quark is mapped to a probe string in the AdS *** the probable contribution of the deformation parameter in the probe string,we apply a general form of c-dependent string ansatz in the drag force ***,we find the acceptable value of this parameter as it satisfies QCD *** this result,we also discuss the diffusion constant which is in agreement with the phenomenological result for the non-relativistic ***,we show that while in absence of a deformation parameter,the probe string is a strictly increasing function of radial coordinate,the c-dependent probe string has a maximum value versus z.

关键词： AdS/QCD drag force deformation parameter