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Dietary(poly)phenol intake is associated with cardiometabolic health parameters in adolescents

Food Science and Human Wellness 2024年

作者： Emily P.Laveriano-Santos sara Castro-Barquero Camila Arancibia-Riveros Ana María Ruiz-León Rosa Casas Ramón Estruch Patricia Bodega Mercedes de Miguel Amaya de Cos-Gandoy Jesús Martínez-Gómez Gloria Santos-Beneit Juan M.Fernández-Alvira Rodrigo Fernández-Jiménez Rosa M.Lamuela-Raventós Anna Tresserra-Rimbau The Zena and Michael A.Wiener Cardiovascular Institute Icahn School of Medicine at Mount Sinai Department de Nutrició Ciències de l'Alimentació I Gastronomia XIA Facultat de Farmàcia i Ciències de l'alimentació Institut de Recerca en Nutrició i Seguretat Alimentària (INSA-UB) Universitat de Barcelona Department of Internal Medicine Hospital Clínic Institutd'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS) University of Barcelona Consorcio CIBER M.P.Fisiopatología de la Obesidad y Nutrición (CIBERObn) Instituto de Salud Carlos III (ISCIII) Mediterranean Diet Foundation 5. Foundation for Science Health and Education (SHE) 6. Centro Nacional de Investigaciones Cardiovasculares (CNIC) CIBER de Enfermedades Cardiovasculares (CIBERCV) 9. Hospital Universitario Clínico San Carlos

Background: The protective role of (poly)phenols against metabolic disorders has been extensively studied in adults but not in ***: To assess associations of dietary (poly)phenols and their subclasses with cardiometabolic health parameters in adolescents. Methods: A cross-sectional study was conducted in 944 individuals aged 11 to 14 years enrolled in the SI! Program for Secondary Schools trial (NCT03504059). (Poly)phenol intake was assessed using semi-quantitative food frequency questionnaires and the Phenol-Explorer database. The measured cardiometabolic parameters were waist circumference (WC) age-sex z-score， blood pressure (BP) age-sex z-score， blood glucose (BG)， triglycerides (TG)， and high-density lipoprotein cholesterol (HDL-c). Multilevel mixed-effect linear regression models were applied to examine the association between (poly)phenol quintiles and cardiometabolic health ***: Compared to the lowest quintile， adolescents in the highest quintile of total (poly)phenol intake had lower WC z-scores (β=-0.09， 95%CI=-0.09;-0.08， P-for trend=0.002)， mean arterial pressure z-scores (β =-0.11， 95%CI=-0.12;-0.09， P-for trend=0.206)， and HDL-c (β=-1.52， 95%CI=-2.90;-0.14， P-for trend=0.108)， after multivariable adjustment. The WC z-scores (β=-0.11， 95%CI=-0.19;-0.03， P-for trend=0.013) and HDL-c (β=-2.16， 95%CI=-3.78;-0.53， P-for trend=0.046) were lower in the highest quintile of flavonoid intake compared to the lowest quintile. The highest quintile of phenolic acid intake was associated with a lower WC z-score (β=-0.14， 95%CI=-0.26;-0.02， P-for trend=0.011) and TG levels (β=-8.83， 95%CI=-12.37;-5.30， P-for trend <0.001)， and the highest quintile of stilbene intake with lower BG (β=-1.83， 95%CI= -3.103;-0.64， P-for trend <0.001) and TG (β=-3.22， 95%CI= -4.95;-1.49， P-for trend=0.034)， and with higher HDL-c (β=2.328， 95%CI= 1.40;3.17， P-for trend=0.466) compared to the lowest quintile. Conclusion: A higher intake of (poly)phenols， espe

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Natural Language Processing with Optimal Deep Learning Based Fake News Classification

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Computers, Materials & Continua 2022年第11期73卷 3529-3544页

作者： sara AAlthubiti Fayadh Alenezi Romany F.Mansour Department of Computer Science College of Computer and Information SciencesMajmaah UniversityAl-Majmaah11952Saudi Arabia Department of Electrical Engineering College of EngineeringJouf UniversitySaudi Arabia Department of Mathematics Faculty of ScienceNew Valley UniversityEl-Kharga72511Egypt

The recent advancements made in World Wide Web and social networking have eased the spread of fake news among people at a faster *** most of the times,the intention of fake news is to misinform the people and make manipulated societal *** spread of low-quality news in social networking sites has a negative influence upon people as well as the *** order to overcome the ever-increasing dissemination of fake news,automated detection models are developed using Artificial Intelligence(AI)and Machine Learning(ML)*** latest advancements in Deep Learning(DL)models and complex Natural Language Processing(NLP)tasks make the former,a significant solution to achieve Fake News Detection(FND).In this background,the current study focuses on design and development of Natural Language Processing with Sea Turtle Foraging Optimizationbased Deep Learning Technique for Fake News Detection and Classification(STODL-FNDC)*** aim of the proposed STODL-FNDC model is to discriminate fake news from legitimate news in an effectual *** the proposed STODL-FNDC model,the input data primarily undergoes pre-processing and Glove-based word ***,STODL-FNDC model employs Deep Belief Network(DBN)approach for detection as well as classification of fake ***,STO algorithm is utilized after adjusting the hyperparameters involved in DBN model,in an optimal *** novelty of the study lies in the design of STO algorithm with DBN model for *** order to improve the detection performance of STODL-FNDC technique,a series of simulations was carried out on benchmark *** experimental outcomes established the better performance of STODL-FNDC approach over other methods with a maximum accuracy of 95.50%.

关键词： Natural language processing text mining fake news detection deep belief network machine learning evolutionary algorithm

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Production and evaluation of novel functional extruded corn snacks fortified with ginger,bay leaves and turmeric powder

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Food Production, Processing and Nutrition 2022年第1期4卷 41-57页

作者： sara Adel Amer Ayat Ebrahim Rizk Special Food and Nutrition Research Department Food Technology Research Institute.Agricultural Research Center9 Gamaa StreetGizaEgypt

Extruded corn snacks are accepted by all human ages especially children, but they have low functional value. Therefore, corn extruded snacks contain rich nutraceuticals dried herbs including Laurus nobilis (T1), Curcuma longa (T2), Zingiber officinale Roscoe (T3), and the mixture of these herbs (T4) were manufactured and analyzed. The results declared that all the herbal extruded corn snacks had significantly higher ash, fibers, minerals, and vitamins A and B6. For minerals, the highest percent of increase compared to control was achieved by Fe, K, Ca, Zn content in order, being the highest in T4. The contents of Vitamin A and B6 were ranged from 283 to 445 IU/100 g and from 0.01 to 0.08 mg/100 g for the herbal extrudates, respectively. The increased percent in herbal corn snacks relative to control ranged from 743 to 452%, 188 to 17.6%, and from 313 to 99% for total phenolics, flavonoids, and antioxidant activity. Besides, the highest number of phenolic compounds was recorded in T4. Despite the fact that approximately all herbal extruded products had good texture and color characteristics, the best formulation was T2 and T4 corn snacks. Furthermore, the extruded products were microbiologically safe for up to 9 months. The formulation of herbal-corn snacks could fulfill consumers’ requirement for ready-to-eat-healthy foods with acceptable sensory attributes and also economically suitable for the food industry.

关键词： Ginger Laurel Turmeric Extrusion Corn snacks functional foods

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Long-term experience with debulking surgery in extensive hepatic alveolar echinococcosis:A case series and literature review

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Asian Pacific Journal of Tropical Medicine 2022年第10期15卷 468-473页

作者： Mohsen Aliakbarian Marcello Di Martino sara Saeidi Department of General Surgery Surgical Oncology Research CenterMashhad University of Medical SciencesMashhadIran Division of Hepatobiliary and Liver Transplantation Surgery.A.O.R.N.Cardarelli NapoliItaly

Objective:To assess the role of debulking surgery in extensive hepatic alveolar echinococcosis(HAE).Methods:Five cases of extensive HAE undergoing debulking surgery with their long-term follow-ups were ***,a systematic review was carried ***:The average age of patients in the study was(50.8±17.1)years(range 36 to 77 years).Three cases were *** median follow-up period was 61 months(range 12 to 84 months).Left liver resections were performed in 2 cases and right hemihepatectomies were undertaken in 2 *** patients(cases 2 and 4)developed early surgical complications,while one of them(case 4)who suffered from the recurrent sub-hepatic abscess died at 12 months ***:This study highlights the importance of debulking surgery for the management of complex symptomatic HAE lesions in patients with no curative option available.

关键词： Alveolar echinococcosis Debulking surgery Reduction Palliative Echinoccocosis multilocularis Case series

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Phenotypical statin-associated immune-mediated necrotizing myositis with histological features of inclusion body myositis

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Rheumatology & Autoimmunity 2023年第1期3卷 50-55页

作者： Nicole Daver sara Tonini Overlook Medical Center Institute for Rheumatic and Autoimmune DiseasesAtlantic Health SystemsSummitNew JerseyUSA

Introduction:Statin-associated immune-mediated necrotizing myositis(IMNM)is a rare but distinct idiopathic inflammatory myopathy(IIM)that requires early recognition and intervention to prevent irreversible muscle *** is typically characterized by active statin use,elevated creatinine kinase(CK)levels,proximal muscle weakness,and at times,a positive 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase(HMGCR)*** includes immediate discontinuation of the statin and may include corticosteroids,intravenous immunoglobulin(IVIG),and/or immunosuppressive *** body myositis(IBM),another distinct IIM,also presents with elevated CK levels but with insidious onset of distal upper and proximal lower extremity weakness and is typically refractory to *** Description:A 64-year-old female patient presented with proximal muscle weakness,elevated CK levels,and a positive HMGCR antibody in the setting of statin use with muscle pathology suggestive of both statinassociated IMNM and *** responded to subcutaneous methotrexate and a slow prednisone taper over several months,however,will require close monitoring for symptoms associated with either ***:In conclusion,we report a case of muscle weakness with muscle pathology demonstrating both statin-associated IMNM and *** case highlights the importance of understanding the clinical and pathological features of statin-associated IMNM and IBM.

关键词： 3-hydroxy-3-methyl-glutaryl-coenzympe A reductase antibody idiopathic inflammatory myopathy immune-mediated necrotizing myositis inclusion body myositis statin-associated myositis

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To resect or not to resect?-the dilemma in oligometastatic breast cancer

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Hepatobiliary Surgery and Nutrition 2022年第4期11卷 623-625页

作者： sara Lonardi Valentina Guarneri Medical Oncology 3 Istituto Oncologico Veneto IOV-IRCCSPaduaItaly Department of Surgery Oncology and GastroenterologyUniversity of PaduaPaduaItaly Medical Oncology 2 Istituto Oncologico Veneto IOV-IRCCSPaduaItaly

Despite the good prognosis of the vast majority of breast cancer cases,about 10%is firstly diagnosed with stage IV,while 20-30%of localized disease treated with curative intent will eventually relapse(1).Hepatic metastases are the third site of relapse,after lymph-nodes and bone,but,due to the early systemic nature of breast cancer,rarely the recurrence is liver-limited.

关键词： breast cancer prognosis

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A methodology for assessing the urban supply of on-street delivery bays

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Green Energy and Intelligent Transportation 2022年第3期1卷 63-72页

作者： Antonio Comi JoséLuis Moura sara Ezquerro University of Rome Tor Vergata RomeItaly University of Cantabria SantanderSpain

The loading and unloading operations carried out by transport and logistics operators have a strong impact on city mobility if they are not performed *** loading/unloading bays,i.e.,delivery bays(DB),are not available for freight vehicle operations,operators may opt to double park or park on the sidewalk where there is no strong enforcement of these laws,with significant impact on *** paper proposes a methodology for verifying and designing the number of delivery bays needed for freight vehicles for not interfere with cars or *** methodology consists of two stages:in the first stage,an initial estimation is made using queueing ***,in the second stage,using such tentative scenario,in order to take into account the system stochasticity involving different entities,a discrete event simulation is performed to more realistically verify and upgrade(if necessary)the number of delivery bays to obtain the expected *** methodology was applied in the inner area of Santander(Spain).The study area was subdivided into 29 zones where the methodology was applied *** results indicated that none of these zones currently have an optimal number of delivery bays to satisfy *** some zones,there is an excess of delivery bays,although in most of them,there is a deficit which can cause significant impacts on *** method proposed can be an effective tool to be used by city planners for improving freight operations in urban areas limiting the negative impacts produced in terms of internal and external costs.

关键词： Urban freight transportation On-street delivery bays Discrete event simulation City logistics Urban goods movements

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Curing Kinetics of Tannin and Lignin Biobased Adhesives Determined by DSC and ABES

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Journal of Renewable Materials 2022年第8期10卷 2117-2131页

作者： Jaša saražin Ida Poljanšek Antonio Pizzi MilanŠernek University of Ljubljana Biotechnical FacultyLjubljana1000Slovenia Universitéde Lorraine LERMAB-ENSTIB Epinal88000France

The curing process of two biobased adhesives:pine tanninhexamine(TH)and organosolv lignin non-isocyanate polyurethane(NIPU),suitable for interior nonstructural use,were compared with commercial urea-formaldehyde(UF)*** in chemical structure before and after the curing process were observed with Fouriertransform infrared spectroscopy(FTIR).The process of adhesive curing was monitored with differential scanning calorimetry(DSC)and the automated bonding evaluation system(ABES).Both DSC and ABES measurements confirmed UF as the fastest and NIPU as the slowest curing adhesive *** into account the ABES results,the optimal pressing parameters for the TH adhesive would be 4 min at 175℃,for the NIPU adhesive 7 min at 200℃and for the UF 1.5 min at 100℃.Strong linear correlation was observed between mechanical and chemical curing for the UF and NIPU adhesives,whereas lower correlation was observed for the TH *** all observed adhesives,the DSC measurements were underestimating the curing process determined by ABES in the first part and overestimating it at the *** underestimation was the most evident with the TH adhesive and the less with the UF *** comparing the uncured and cured FTIR spectra of all three types of adhesives,a drastic decrease in the characteristic band of-OH groups at 3330–3400 cm^(−1)and an increase in the signal intensity at 2920 cm^(−1)of aliphatic-CH2-groups were *** the UF adhesive,the C=O stretching frequency has shifted from 1632 cm^(−1)for uncured to three different bands at 1766,1701,and 1655 cm^(−1)for cured *** sharp band for phenolic alcohols at 1236 cm^(−1)of C–O stretch and hydroxyl O–H functional group at 1009 cm^(−1)and at 684 cm^(−1)of uncured TH adhesive diminished during curing,which indicates that a crosslinking reaction occurs via-OH *** peak of the C=O group of urethane bridges at 1697 cm^(−1)for uncured NIPU shifted to lower wavenumber at 1633 cm^(−1)for cured NIPU.

关键词： Biobased adhesives curing kinetics tannin lignin ABES DSC FTIR

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Behavioral and endocrine responses to noninteractive live and video conspecifics in males of the Siamese fighting fish

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Current Zoology 2023年第5期69卷 568-577页

作者： Deepa Alex sara DCardoso Andreia Ramos David Gonçalves Institute of Science and Environment University of Saint JosephRua de Londres 106Macao SARChina

The physiological mechanisms underlying variation in aggression in fish remain poorly *** possibly confounding variable is the lack of standardization in the type of stimuli used to elicit *** presentation of controlled stimuli in videos,*** playback,can provide better control of the fight ***,this technique has produced conflicting results in animal behavior studies and needs to be carefully *** this,a similar response to the video and an equivalent live stimulus needs to be ***,different physiological responses may be triggered by live and video stimuli,and it is important to demonstrate that video images elicit appropriate physiological ***,the behavioral and endocrine responses of male Siamese fighting fish Betta splendens to a matched-for-size conspecific fighting behind a one-way mirror,presented live or through video playback,were *** video playback and live stimulus elicited a strong and similar aggressive response by the focal fish,with a fight structure that started with stereotypical threat displays and progressed to overt *** plasma levels of the androgen 11-ketotestosterone were elevated as compared to controls,regardless of the type of *** also increased in response to the video images,as previously described for live fights in this *** results show that the interactive component of a fight and its resolution are not needed to trigger an endocrine response to aggression in this *** study also demonstrates for the first time in a fish a robust endocrine response to video stimuli and supports the use of this technique for researching aggressive behavior in ***.

关键词： aggression androgens corticosteroids Betta splendens one-way mirror video playback

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City Digital Twins: their maturity level and differentiation from 3D city models

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Big Earth Data 2023年第1期7卷 1-36页

作者： Homa Masoumi sara Shirowzhan Paria Eskandarpour Christopher James Pettit Department of Urban and Regional Planning Shahid Beheshti UniversityTehranIran School of Built Environment UNSW SydneySydneyAustralia Faculty of Information Technology Monash UniversityClaytonVICAustralia Faculty of Arts Design and ArchitectureCity Futures Research CentreUNSW SydneyNSWAustralia

The emerging field of City Digital Twins has advanced in recent years with the help of digital infrastructure and technologies connected to the Internet of Things(IoT).However,the evolution of this field has been so fast that a gap has opened in relation to systematic reviews of the relevant literature and the maturation of City Digital Twins on an urban *** work bridges this gap by highlighting maturity in the *** conducted a systematic literature review with bibliometric and content analysis of 41 selected papers published in Web of Science and Scopus data-bases,covering five areas:data types and sources,case studies,applied technologies and methods,maturity spectrum,and *** on maturity indicators,the majority of the reviewed studies(90%)were at initial to medium stages of maturity(up to element 3),most of them focused on 3D modelling,monitoring and ***,digital twins cannot be limited to 3D models,monitoring and visualisation,for they can be developed to include two-directional interactions between humans and *** a high level of maturity,which was not found in the reviewed studies,requires advanced technologies and methods such as cloud computing,artificial intelligence,BIM and *** also found that further studies are essential if the field is to handle the complex urban challenges of multidisciplinary digital *** City Digital Twins extend by definition beyond mere 3D city modelling,some studies involving 3D city models still refer to their subjects as City Digital *** the research gaps we identified,we’d like to highlight the need for near-real-time data analytics algorithms,which could furnish City Digital Twins with big data *** opportunities include public participation capabilities to increase social collaboration,integrating BIM and GIS technologies and improving storage and computation infrastructure.

关键词： City Digital Twins big data IoT artificial intelligence city information modelling

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