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Numerical modelling of post-failure behaviors of coal specimens

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第2期16卷 514-531页

作者： Ajeet Yadav Bhaskara Behera Gauri Shankar Prasad Singh sanjay kumar Sharma Department of Mining Engineering Indian Institute of Technology(Banaras Hindu University)VaranasiUttar Pradesh221005India

A modelling approach consisting of best-fit relations to estimate the post-yield strength parameters is presented for simulating post-peak behavior beyond the point of residual strength of coal pillars having different w/h *** model was developed based on back-analysis of the complete stress-strain behavior of specimens belonging to six different Indian coal seams with different w/h ratios of 0.5 *** was found that the simultaneous degradation of the cohesion and friction angle of the Mohr-Coulomb rock material characterizes the post-peak strength behavior of the *** resulting expressions are simplistic as they require parameters that can be easily determined using uniaxial and triaxial compression ***,the developed model was validated by simulating the triaxial tests of coal specimens with different sizes under varying confining stresses and comparing its findings with the published test *** study showed that its implementation in the numerical model could reproduce laboratory-observed mechanical response,deformation behavior,and failure mechanism very closely.

关键词： Strain softening Dilatancy Interface Shape effect Residual strength

Resistance and resilience of soil biological indicators:A case study with multi-walled carbon nanotube

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Pedosphere 2024年第3期34卷 664-675页

作者： Shagufta YASMEEN Nintu MANDAL Anupam DAS Pritam GANGULY sanjay kumar Rajiv RAKSHIT Department of Soil Science and Agricultural Chemistry Bihar Agricultural UniversitySabourBhagalpur 813210(India) Department of Agronomy Bihar Agricultural UniversitySabourBhagalpur 813210(India)

Soil ecosystem is experiencing stresses due to climate change,and soil inhabitants try to demonstrate their inherent resistance and resilience against those *** of nanomaterials as agricultural inputs could bring shifts in resistance and resilience patterns of soil microbes and associated enzymes,especially under short-term heat *** this background,the impacts of multi-walled carbon nanotube(MWCNT)on the resistance and resilience of soil biological indicators were *** incubation experiment was conducted with varied MWCNT concentrations(0,50,100,250,and 500 mg kg-1soil)for 90 d after 24-h heat stress at 48±2?C to assess the impacts of MWCNT on soil enzyme activities and microbial populations vis-à-vis their resistance and resilience indices under short-term exposure to heat *** activities were reduced after exposure to heat *** indices of enzyme activities were enhanced by MWCNT application on day 1 after heat stress,whereas there was no recovery of enzyme activities after 90-d *** soil enzyme activities,resistance index values of soil microbial populations followed the similar trend and were improved by MWCNT ***-walled carbon nanotube has the potential to improve resistance indices of soil enzyme activities and microbial populations under heat stress,although they could not recover to their original state during periodical incubation after heat *** study helps to understand the relative changes of biological indicators under MWCNT and their ability to withstand heat stress.

关键词： enzyme activity heat stress microbial population nanomaterial recovery

Recombinant vaccines:Current updates and future prospects

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Asian Pacific Journal of Tropical Medicine 2024年第8期17卷 338-350页

作者： Vivek kumar Anuj Verma Riddhi Singh Priyanshi Garg Santosh kumar Sharma Himanshu Narayan Singh Santosh kumar Mishra sanjay kumar Department of Allied Medical Sciences School of Allied Medical SciencesLovely Professional UniversityPhagwaraPunjabIndia Bioengineering Division of Department of Bioscience and Biomedical EngineeringIndian Institute of Technology BhilaiChhattisgarhIndia Department of Biotechnology IMS Engineering CollegeGhaziabadU.P.India Department of Chemistry and Biochemistry University of WindsorOntario N9B3P4Canada Biological and Biocomputational Laboratory Department of Life SciencesSharda School of Basic Sciences and ResearchSharda UniversityGreater NoidaU.P.India Department of System Biology Columbia University Irving Medical CenterNew YorkNY 10032USA Department of Life Sciences Sharda School of Basic Sciences and ResearchSharda UniversityGreater NoidaU.P.India

Recombinant technology-based vaccines have emerged as a highly effective way to prevent a wide range of *** technology improved vaccine manufacturing,rendering it more efficient and *** vaccines have multiple advantages compared to conventional *** pandemic has heightened awareness of the advantages of these vaccine technologies;trust and acceptance of these vaccines are steadily growing *** work offers an overview of the prospects and advantages associated with recombinant ***,it discusses some of the challenges likely to arise in the *** ability to target diverse pathogen classes underscores their contributions to preventing previously untreatable diseases(especially vector-borne and emerging diseases)and hurdles faced throughout the vaccine development process,especially in enhancing the effectiveness of these ***,their compatibility with emerging vaccination platforms of the future like virus-like particles and CRISPR/Cas9 for the production of next-generation vaccines may offer many *** review also reviewed the hurdles faced throughout the vaccine development process,especially in enhancing the effectiveness of these vaccines against vector-borne diseases,emerging diseases,and untreatable diseases with high mortality rates like AIDS as well as cancer.

关键词： Malaria Dengue Emerging diseases Immunoinformatics Virus-like particles CRISPR-Cas9

Machine Learning Techniques Using Deep Instinctive Encoder-Based Feature Extraction for Optimized Breast Cancer Detection

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Computers, Materials & Continua 2024年第2期78卷 2441-2468页

作者： Vaishnawi Priyadarshni sanjay kumar Sharma Mohammad Khalid Imam Rahmani Baijnath Kaushik Rania Almajalid Department of Computer Science Gautam Buddha UniversityGreater NoidaUttar PradeshIndia College of Computing and Informatics Saudi Electronic UniversityRiyadh11673Saudi Arabia School of Computer Science Shri Vaishno Devi UniversityKatraIndia

Breast cancer(BC)is one of the leading causes of death among women worldwide,as it has emerged as the most commonly diagnosed malignancy in *** detection and effective treatment of BC can help save women’s *** an efficient technology-based detection system can lead to non-destructive and preliminary cancer detection *** paper proposes a comprehensive framework that can effectively diagnose cancerous cells from benign cells using the Curated Breast Imaging Subset of the Digital Database for Screening Mammography(CBIS-DDSM)data *** novelty of the proposed framework lies in the integration of various techniques,where the fusion of deep learning(DL),traditional machine learning(ML)techniques,and enhanced classification models have been deployed using the curated *** analysis outcome proves that the proposed enhanced RF(ERF),enhanced DT(EDT)and enhanced LR(ELR)models for BC detection outperformed most of the existing models with impressive results.

关键词： Autoencoder breast cancer deep neural network convolutional neural network image processing machine learning deep learning

Pain management in chronic pancreatitis

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World Journal of Clinical Cases 2024年第12期12卷 2016-2022页

作者： Deb sanjay Nag Bhanu Pratap Swain Rishi Anand Tapas kumar Barman Vatsala Department of Anaesthesiology Tata Main HospitalJamshedpur 831001India

Pain in chronic pancreatitis(CP)is difficult to *** patients suffer from inadequate pain relief,completely incapacitating them in their daily ***,despite their well-known adverse effects,opioids have been the pillar of treatment regimens in painful *** management is now gradually evolving with a better understanding of the underlying pathophysiology of CP-related *** should follow a holistic approach to the management of CPassociated pain,which must involve lifestyle changes that are coupled with analgesic medications and other pain-relieving ***,there is no easy cure for vanquishing CP-associated *** patient must be evaluated on a case-by-case basis by a multidisciplinary team to decide which treatment option is best suited for that individual.

关键词： Pancreatitis Abdominal pain Palliative care Analgesics Life style Psychology

Perioperative cardiac risks in myasthenia gravis

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World Journal of Clinical Cases 2024年第13期12卷 2147-2150页

作者： Deb sanjay Nag Abhishek Chatterjee Pratap Rudra Mahanty Merina Sam Murari kumar Bharadwaj Department of Anaesthesiology Tata Main HospitalJamshedpur 831001India Department of Anaesthesiology Manipal Tata Medical CollegeJamshedpur 831017India

Myasthenia gravis(MG)is an autoimmune disorder that affects the neuromuscular *** primary pathology in MG involves the presence of autoantibodies to acetylcholine receptors(AChRs),which results in qualitative and quantitative reductions in the availability of functional *** muscles are also affected,resulting in various perioperative cardiac *** antibodies are commonly reported in MG cases with cardiac *** the presence of thymoma,the prevalence of cardiac manifestations in patients with MG increases to approximately 10%-15%.Cardiac involvement in MG may range from asymptomatic electrocardiogram changes to ventricular tachycardia,myocarditis,conduction disorders,heart failure,and sudden *** incidence of atrial fibrillation,ventricular and supraventricular extra systoles,and prolonged QTc have also been reported in patients with *** should consider the evaluation of autonomic dysfunction and risk of cardiovascular disease in patients with MG.

关键词： Myasthenia Gravis Perioperative period Receptors Cholinergic Anesthesia

Knowledge and practice skills on home-based urinary catheter care among parents of under-five children with urinary catheter

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Journal of Integrative Nursing 2024年第1期6卷 29-34页

作者： Kurvatteppa HALEMANI sanjay DHIRAAJ Basant kumar Saadhat HUSSAN Premalata Prerna PAWAN Priyanshi Raviraj GUPTA College of Nursing All India Institute of Medical SciencesRaebareliUttar PradeshIndia Department of Anesthesiology Sanjay Gandhi Post Graduate Institute of Medical SciencesLucknowUttar PradeshIndia Department of Pediatric Surgery Sanjay Gandhi Post Graduate Institute of Medical SciencesLucknowUttar PradeshIndia

Objectives:The objectives of this study were to assess the knowledge and practice skills on home-based urinary catheter care among parents of under-five children with urinary *** and Methods:This cross-sectional study was conducted from June 1,2021,to September 11,2021,in a tertiary hospital in north *** sampling was used to select 50 *** instruments were employed for data collection after fulfilling sample criteria;for baseline information demographic tool,knowledge questionnaires,and a practice *** were analyzed using descriptive and inferential ***:On assessment of 50 participants,the majority of parents aged above 30 years(74%).Most of the participants were male(82%),graduated(38%),and working in the private sector(58%).Similarly,two-thirds of participants were residing in a nuclear family(64%)with a single child 32(64%)and family income<5000 rupees per month(60%).The mean score of knowledge was 1.94±0.81 and that of practice skills was 1.98±0.85 on home-based *** analysis showed that knowledge of parents was significantly associated with qualification(β:1.821,P=0.002).Similarly,association of practice skills of parents with gender(β:1.235,P=0.050)and qualification(β:1.889,P=0.00)was ***:The general findings of our study showed that parents’education and occupation played a significant role in a child’s *** education and catheter care skills positively affect the child and reduce readmission rates.

关键词： Home-based care knowledge parents practice urinary catheter

Current evidence on artificial intelligence in regional anesthesia

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World Journal of Clinical Cases 2024年第33期12卷 6613-6619页

作者： Bhanu Pratap Swain Deb sanjay Nag Rishi Anand Himanshu kumar Pradip kumar Ganguly Niharika Singh Department of Anaesthesiology Tata Main HospitalJamshedpur 831001India Department of Anesthesiology Manipal Tata Medical CollegeJamshedpur 831017India

The recent advancement in regional anesthesia(RA)has been largely attributed to ultrasound ***,the safety and efficiency of ultrasound-guided nerve blocks depend upon the skill and experience of the *** with adequate training,experience,and knowledge,human-related limitations such as fatigue,failure to recognize the correct anatomical structure,and unintentional needle or probe movement can hinder the overall effectiveness of *** amalgamation of artificial intelligence(AI)to RA practice has promised to override these human *** learning,an integral part of AI can improve its performance through continuous learning and experience,like the human *** enables computers to recognize images and patterns specifically useful in anatomic structure identification during the performance of *** can provide real-time guidance to clinicians by highlighting important anatomical structures on ultrasound images,and it can also assist in needle tracking and accurate deposition of local *** future of RA with AI integration appears promising,yet obstacles such as device malfunction,data privacy,regulatory barriers,and cost concerns can deter its clinical *** current mini review deliberates the current application,future direction,and barrier to the application of AI in RA practice.

关键词： Artificial intelligence Regional anesthesia Machine learning Ultrasonography Nerve block

Jet modification in absence of QGP-medium:the role of multiparton interactions and color reconnection

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Chinese Physics C 2024年第1期48卷 50-60页

作者： Prottoy Das Abhi Modak Debjani Banerjee Rathijit Biswas Supriya Das sanjay KGhosh Sibaji Raha Sidharth kumar Prasad Department of Physics Bose InstituteKolkata 700091India Quark Matter Research Center Institute of Modern PhysicsChinese Academy of SciencesLanzhou 730000China

Recent studies on high-multiplicity events in small collision systems(proton-proton and proton-lead)have drawn considerable research interest toward the possibility of the formation of partonic medium in such *** of the important consequences of the formation of dense partonic medium is the quenching of high-momentum final-state particles,resulting in several experimental observations such as suppression in nuclear modification factor RAA,modification of jet shape observableρ(r)and jet fragmentation(z^(ch))distributions,*** this work,we studyρ(r)and z^(ch)for inclusive charged-particle jets in proton-proton(pp)collisions at√s=13 TeV using the PYTHIA 8 Monash 2013 Monte Carlo *** show that the color reconnection(CR)and multiparton interaction(MPI)mechanisms in PYTHIA 8 can lead to an increased rate of jet *** also find that the mechanisms of MPI and CR and change in the gluonic contribution in high-multiplicity events result in significant modification ofρ(r)and z^(ch)compared to those in minimum bias events for 10and gluonic contribution with the amount of modification inρ(r):the larger the number of MPIs and/or gluonic contribution,the larger the amount of modification ofρ(r).

关键词： jet modification PYTHIA multiparton interaction color reconnection gluonic contribution high-multiplicity