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Glutathione Enzymes and Liver Injury in Acute dengue Viral Infection

Journal of Biosciences and Medicines 2019年第10期7卷 61-71页

作者： Lal Chandrasena Arjuna de Silva Chandima de mel Hemantha Peiris Visula Abesuriya sanjay de mel Suranjith Seneviratne Samantha Bandara Nawaloka Hospitals Research and Education Foundation Nawaloka Hospitals PLC Colombo Sri Lanka department of Medicine Faculty of Medicine University of Kelaniya Kelaniya Sri Lanka department of Biochemistry Faculty of Medical Sciences University of Sri Jayewardenepura Nugegoda Sri Lanka department of Haematology-Oncology National University Cancer Institute National University Health System Singapore Singapore Institute of Immunity and Transplantation Royal Free Hospital and University College London London UK department of Medical Laboratory Sciences Faculty of Allied Health Sciences University of Sri Jayewardenepura Nugegoda Sri Lanka

Identification of redox markers may be of clinical significance in the management of dengue patients. This study is to identify the association between antioxidant enzymes, hematological parameters and liver transaminases in patients with acute dengue infection. Blood samples were taken from patients on the day of admission, day 05 and 07 from admission for analysis of glutathione peroxidase (GPX), glutathione reductase (GR), aspartate transaminase (AST), alanine transaminase (ALT) and hematological parameters. AST and ALT levels were significantly elevated (p dengue patients. In contrast, GPX and GR showed significantly low levels on day 05 compared to on the day of admission and day 07. Although there was a decline in the trend of platelets towards day 05, values were not significantly different. dengue associated with liver injury appears to peak around day 05 when the GPX and GR enzymes levels in patients were the lowest suggesting that increased viral load in the acute phase of dengue infection has initiated an antioxidant imbalance. Thus, timely investigation of antioxidant enzymes (GR and GPX) and liver transaminases around day 05 of admission may be of value in the management of patients with dengue infection similar to as seen in platelet counts.

关键词： Aspartate Transaminase Alanine Transaminase dengue Glutathione Peroxidase Glutathione Reductase

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Glutathione Reductase, Liver Transaminases and Atypical Lymphocytes Count as Early Predictive Biomarkers in Diagnosis of Thrombocytopenia in dengue Viral Infection

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Journal of Biosciences and Medicines 2021年第1期9卷 119-130页

作者： Samantha Bandara Lal G. Chandrasena Hemantha Peiris Visula Abesuriya Arjuna de Silva Chandima de mel sanjay de mel Suranjith L. Seneviratne department of Medical Laboratory Sciences Faculty of Allied Health Sciences University of Sri Jayewardenepura Nugegoda Sri Lanka Nawaloka Hospitals Research and Education Foundation Nawaloka Hospitals PLC Colombo Sri Lanka department of Biochemistry Faculty of Medical Sciences University of Sri Jayewardenepura Nugegoda Sri Lanka department of Medicine Faculty of Medicine University of Kelaniya Ragama Sri Lanka department of Haematology-Oncology National University Cancer Institute National University Health System Singapore Institute of Immunity and Transplantation Royal Free Hospital and University College London UK

Objective: The aim of the study is to identify whether Atypical Lymphocyte (AL), liver transaminases, and Glutathione Reductase (GR) can be used as potential biomarkers in the assessment of severity and thrombocytopenia in dengue. Methods: A cross-sectional analytical study was carried out on diagnosed dengue patients admitted to Nawaloka Hospital, Sri Lanka. Blood samples were taken from patients (n = 50) on the day of admission, 3rd and 5th day from admission for analysis of GR, aspartate transaminase, alanine transaminase, platelets, white blood cells, and Atypical Lymphocytes (AL). Results: GR level of all three measured stages had a higher area under the curve (>88%), high sensitivity and specificity compared to liver transaminases. A significant regression model represents on admission GR and AL levels as predictive variables to platelet levels in day 03 from admission (Day 3 Platelet level = 127155.3 - 383 * GR - 0.431 * AL). Conclusion: Liver transaminases, GR, and AL% can be considered as a profile of predictive biomarkers in early diagnosis of severity of dengue infection. The degree of thrombocytopenia can be predicted using on admission GR and AL% level in acute dengue viral infection.

关键词： dengue Liver Transaminases Glutathione Reductase Atypical Lymphocytes

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用于大型乘用车的传动带驱动电动转向

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汽车与配件 2009年第27期 26-28页

作者： sanjay Singh Christos Mantzios mel Sharp TRW汽车集团

传动带驱动技术(有时候也被称为齿条驱动),使得EPS系统用于较大重量的车辆成为可能,这里提到的较大重量的车辆包括中级乘用车、小型及轻型货车、小型及中型运动型多用途车。

关键词：驱动技术传动带乘用车电动转向运动型多用途车 EPS系统轻型货车车辆

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两种类型的数字音频篡改检测算法研究

两种类型的数字音频篡改检测算法研究

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作者： sanjay KUMAR ROUNIYAR 华南理工大学

学位级别：硕士

最近,越来越多用户使用多媒体设备。由于市场趋势和不同类型的电子产品的需求,各种便携式记录设备容易获得,使得将音频资料从一个地方转移到另一个地方非常容易。在现实生活中,强大的软件实用性强,用途广泛,有许多功能强大的数字音频编... 详细信息

最近,越来越多用户使用多媒体设备。由于市场趋势和不同类型的电子产品的需求,各种便携式记录设备容易获得,使得将音频资料从一个地方转移到另一个地方非常容易。在现实生活中,强大的软件实用性强,用途广泛,有许多功能强大的数字音频编辑软件,可以轻松编辑音频文件并实现所需的更改。这些被操纵的音频文件,如果在法院作为司法程序作为证据使用时,对于任何原因或事件中的证据都可能导致不良后果,这些后果可能会在社会或者在其他任何形式下都是不想看到的。因此,识别数字音频文件的完整性以及音频取证的重要性变得非常重要。数字音频篡改检测技术正在不同机构中广泛使用,以检查音频数据的可靠性和真实性。这项研究工作主要集中在基于内容的复制粘贴篡改检测和拼接篡改检测。这项研究工作的主要工作如下:1.讨论并解释数字音频篡改检测的基本原理;以及数字音频篡改检测技术的一般检测流程。模拟两种不同的音频篡改检测方法,并分析实验结果并指出其局限性。2.本文针对同音频数字音频复制篡改行为,提出了一种基于距离相似性度量的篡改识别和定位方法。通过使用距离相似性度量来确定音频特征的相似程度。欧式距离和切比雪夫距离是本文所提出的方法中所使用的距离度量。基音频率是音频特征之一,本文使用基音跟踪(Yet Another Algorithm for Pitch Tracking(YAAPT))算法来提取基音序列特征,通过计算距离并与阈值进行比较,来确定音频文件中的复制粘贴篡改。该方法能够在提高运算时间的同时有效地检测复制篡改检测,并在检测的同时提高准确率。3.本文提出了一种基于信道响应多特征联合的音频拼接检测与定位方法。使用Relative Spectra-mel Frequency Cepstral Coefficient(RASTA-MFCC)系数的高斯混合模型(GMM)来进行盲信道估计。使用音频信号的信道响应以及待测信号的对数谱特征的动态和静态信息来构建篡改和定位的特征。然后采用序列前向选择(SFS)算法来进行特征选取。最后在定位检测时,我们首先确定音频是否被篡改,然后以多个起始音频帧特征的平均值作为参考特征,分别计算参考特征和每个其他音频特征帧的相关系数,判断相关系数的一致性是否发生变化来检测篡改。与现有算法相比,该算法提高了篡改的检测率。

关键词：数字音频取证音频复制粘贴检测音频拼接篡改检测距离的相似度序列前向选择(SFS)

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Fungal diversity notes 1387-1511:taxonomic and phylogenetic contributions on genera and species of fungal taxa

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Fungal Diversity 2021年第6期111卷 1-335页

作者： Saranyaphat Boonmee Dhanushka N.Wanasinghe Mark S.Calabon Naruemon Huanraluek Sajini K.U.Chandrasiri Gareth E.B.Jones Walter Rossi Marco Leonardi sanjay K.Singh Shiwali Rana Paras N.Singh deepak K.Maurya Ajay C.Lagashetti deepika Choudhary Yu-Cheng Dai Chang-Lin Zhao Yan-Hong Mu Hai-Sheng Yuan Shuang-Hui He Rungtiwa Phookamsak Hong-Bo Jiang María P.Martín Margarita Dueñas MTeresa Telleria Izabela L.Kałucka Andrzej M.Jagodziński Kare Liimatainen Diana S.Pereira Alan J.L.Phillips Nakarin Suwannarach Jaturong Kumla Surapong Khuna Saisamorn Lumyong Tarynn B.Potter Roger G.Shivas Adam H.Sparks Niloofar Vaghefi Mohamed A.Abdel-Wahab Faten A.Abdel-Aziz Guo-Jie Li Wen-Fei Lin Upendra Singh Rajendra P.Bhatt Hyang Burm Lee Thuong T.T.Nguyen Paul M.Kirk Arun Kumar Dutta Krishnendu Acharya VVenkateswara Sarma M.Niranjan Kunhiraman C.Rajeshkumar Nikhil Ashtekar Sneha Lad Nalin N.Wijayawardene Darbe J.Bhat Rong-Ju Xu Subodini N.Wijesinghe Hong-Wei Shen Zong-Long Luo Jing-Yi Zhang Phongeun Sysouphanthong Naritsada Thongklang Dan-Feng Bao Janith V.S.Aluthmuhandiram Jafar Abdollahzadeh Alireza Javadi Francesco Dovana Muhammad Usman Abdul Nasir Khalid Asha J.Dissanayake Anusha Telagathoti Maraike Probst Ursula Peintner Isaac Garrido-Benavent Lilla Bóna Zsolt Merényi Lajos Boros Bratek Zoltán JBenjamin Stielow Ning Jiang Cheng-Ming Tian Esmaeil Shams Farzaneh dehghanizadeh Adel Pordel Mohammad Javan-Nikkhah Teodor T.denchev Cvetomir M.denchev Martin Kemler Dominik Begerow Chun-Ying deng Emma Harrower Tohir Bozorov Tutigul Kholmuradova Yusufjon Gafforov Aziz Abdurazakov Jian-Chu Xu Peter E.Mortimer Guang-Cong Ren Rajesh Jeewon Sajeewa S.N.Maharachchikumbura Chayanard Phukhamsakda Ausana Mapook Kevin D.Hyde Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand CAS Key Laboratory for Plant Biodiversity and Biogeography of East Asia(KLPB) Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanPeople’s Republic of China CIFOR-ICRAF China Program World Agroforestry(ICRAF)Kunming 650201YunnanPeople’s Republic of China Honghe Center for Mountain Futures Kunming Institute of BotanyHonghe CountyKunming 654400YunnanPeople’s Republic of China department of Botany and Microbiology College of ScienceKing Saud UniversityP.O.Box 2455Riyadh 11451Saudi Arabia Section Environmental Sciences Department MeSVAUniversity of L’Aquila67100 CoppitoAQItaly National Fungal Culture Collection of India(NFCCI) Biodiversity and Palaeobiology GroupMACS Agharkar Research InstituteG.G.Agarkar RoadPune 411004India Institute of Microbiology School of Ecology and Nature ConservationBeijing Forestry UniversityBeijing 100083People’s Republic of China College of Biodiversity Conservation Southwest Forestry UniversityKunming 650224People’s Republic of China CAS Key Laboratory of Forest Ecology and Management Institute of Applied EcologyChinese Academy of SciencesShenyang 110164People’s Republic of China University of the Chinese Academy of Sciences Beijing 100049People’s Republic of China Centre for Mountain Futures(CMF) Kunming Institute of BotanyKunming 650201YunnanPeople’s Republic of China department of Mycology Real Jardín Botánico-CSICPlaza de Murillo 228014 MadridSpain department of Algology and Mycology Faculty of Biology and Environmental ProtectionUniversity of LodzBanacha 12/1690-237ŁódźPoland Institute of dendrology Polish Academy of SciencesParkowa 562-035 KórnikPoland Jodrell Laboratory Royal Botanic GardensKewRichmond TW93DSSurreyUK Faculdade de Ciências Biosystems and Integrative Sciences Institute(BioISI)Universidade de LisboaCampo Grande1749-016 LisbonPortugal dep

This article is the 13th contribution in the Fungal Diversity Notes series,wherein 125 taxa from four phyla,ten classes,31 orders,69 families,92 genera and three genera incertae sedis are treated,demonstrating worldwide and geographic *** taxa described and illustrated in the present study include three new genera,69 new species,one new com-bination,one reference specimen and 51 new records on new hosts and new geographical *** new genera,Cylindrotorula(Torulaceae),Scolecoleotia(Leotiales genus incertae sedis)and Xenovaginatispora(Lindomycetaceae)are introduced based on distinct phylogenetic lineages and unique *** described species are Aspergillus lan-naensis,Cercophora dulciaquae,Cladophialophora aquatica,Coprinellus punjabensis,Cortinarius alutarius,***-latus,***,Coryneum fagi,Cruentomycena uttarakhandina,Cryptocoryneum rosae,Cyathus uniperidiolus,Cylindrotorula indica,Diaporthe chamaeropicola,Didymella azollae,Diplodia alanphillipsii,Dothiora coronicola,Efibula rodriguezarmasiae,Erysiphe salicicola,Fusarium queenslandicum,Geastrum gorgonicum,***,Helicosporium sexualis,Helminthosporium chiangraiensis,Hongkongmyces kokensis,Hydrophilomyces hydraenae,Hygrocybe boertmannii,Hyphoderma australosetigerum,Hyphodontia yunnanensis,Khaleijomyces umikazeana,Laboulbenia divisa,Laboulbenia triarthronis,Laccaria populina,Lactarius pallidozonarius,Lepidosphaeria strobelii,Longipedicellata megafusiformis,Lophiotrema lincangensis,Marasmius benghalensis,***,***,Mariannaea camelliae,mel-anographium smilaxii,Microbotryum polycnemoides,Mimeomyces digitatus,Minutisphaera thailandensis,Mortierella solitaria,Mucor harpali,Nigrograna jinghongensis,Odontia huanrenensis,***,Paraconiothyrium ajrekarii,Par-afuscosporella niloticus,Phaeocytostroma yomensis,Phaeoisaria synnematicus,Phanerochaete hainanensis,Pleopunctum thailandicum,Pleurotheciella dimorphospora,Pseudochaetosphaeronema

关键词： 72 new taxa One new combination One reference specimen 51 new records Agaricomycetes Ascomycota Bartheletiomycetes Basidiomycota Dothideomycetes Eurotiomycetes Exobasidiomycetes Laboulbeniomycetes Leotiomycetes Mortierellomycetes Mortierellomycota Mucoromycetes Mucoromycota Phylogeny Sordariomycetes Taxonomy

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