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Analysis of particle dispersion and cavity formation during bulk particle water entry using fully coupled CFD-DEM-VOF approach

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Particuology 2024年第7期90卷 558-580页

作者： Utkan Çalışkan sanja mišković Norman B.Keevil Institute of mining Engineering University of British Columbia2329 West MallVancouverBC V6T 1Z4Canada

This paper presents the development and validation of a fully coupled computational fluid dynamics—discrete element method—volume of fluid(CFD-DEM-VOF)model to simulate the complex behavior of particle-laden flows with free *** coupling between the fluid and particle phases is established through the implemented continuity,momentum,and alpha transport *** coupled particle forces such as drag,pressure gradient,dense virtual mass,viscous,and interface forces are also integrated,with drag and dense virtual mass forces being dependent on local *** integrated conservative alpha transport equation ensures phase volume conservation during interactions between particles and ***,we have implemented a trilinear interpolation method designed to operate on unstructured hexahedral *** method has been tested for its ability to properly resolve the coupling effects in the numerical simulations,particularly in cases with a relatively low cell-size *** model is validated through three distinct test cases:single particle water entry,dam break with particles,and water entry of a group of particles *** experimental setup is built to study the dynamics of the water entry of a group of particles,where three key flow features are analyzed:the evolution of average particle velocity,cavity shape,and particle dispersion cloud profiles in *** tests involve four different scenarios,including two different water levels(16.1 and 20.1 cm)and two different particle densities(2650 and 4000 kg/m3).High-speed videometry and particle tracking velocimetry(using ImageJ/TrackMate)methods are employed for experimental data *** is demonstrated that numerical results are in excellent agreement with theoretical predictions and experimental *** study highlights the significance of vortices in cavity shaping and particle *** validated CFD-DEM-VOF model constitutes a robust tool for simulating particle-laden flows,cont

关键词： CFD-DEM-VOF Trilinear interpolation Particle-laden flow Free-surface Particle water entry Volume conservation

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CFD simulation of single-phase flow in flotation cells:Effect of impeller blade shape,clearance,and Reynolds number

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International Journal of mining Science and Technology 2019年第5期29卷 657-669页

作者： Manjunath Basavarajappa sanja miskovic Department of Metallurgical Engineering University of UtahSalt Lake City 84112United States INEOS Pigments 6752 Baymeadow DriveGlen Burnie 21061United States Norman B.Keevil Institute of mining Engineering The University of British ColumbiaBritish Columbia V6T 1Z4Canada

A series of numerical simulations of turbulent single-phase flows are performed to understand the flow and mixing characteristics in a laboratory scale flotation *** impeller blade shapes covering a wide range of surface areas and lip lengths are considered to highlight and contrast the flow behavior predicted in the impeller *** mean flow close to the impeller is fully characterized by considering velocity components along the axial direction at different radial *** results suggest the development of a comparatively stronger axial velocity component for a blade design with the smallest lip length,called big-tip impeller *** turbulent kinetic energy profiles close to the impeller reveal the existence of an asymmetric trailing vortex *** highest turbulence kinetic energy dissipation rates are observed close to the impeller blades and stator walls where the radial jet strikes the stator walls ***,liquid phase mixing in the flotation cell is studied using transient scalar tracing simulations providing mixing time ***,pumping capacity and efficiency of different impeller designs are calculated based on which the impeller blade design with a rectangular blade design is found to perform most efficiently.

关键词： Flotation Impeller blade design Turbulent flow mixing Pumping efficiency

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Levels of evidence and grades of recommendation supporting European society for medical oncology clinical practice guidelines

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Oncology Research 2024年第5期32卷 807-815页

作者： MARKO SKELIN BRUNA PERKOV-STIPIČIN sanja VUŠkoviĆ MARINAŠANDRK PLEHAČEK ANE BAŠIĆ DAVIDŠARČEVIĆ MAJA ILIĆ IVAN KREČAK Pharmacy Department General Hospital ofŠibenik-Knin CountyŠibenikCroatia Faculty of Medicine University of RijekaRijekaCroatia Undergraduate Study in Nursing University of Applied SciencesŠibenikCroatia Department of Oncology University Hospital Center ZagrebZagrebCroatia Pharmacies Joukhadar Sveta NedeljaCroatia Pharmacies Prima Pharme ZagrebCroatia Pharmacy Department General Hospital ZadarZadarCroatia Pharmacy Department General Hospital PulaPulaCroatia Department of Internal Medicine General Hospital ofŠibenik-Knin CountyŠibenikCroatia

Background:The European Society for Medical Oncology(ESMO)guidelines are among the most comprehensive and widely used clinical practice guidelines(CPGs)***,the level of scientific evidence supporting ESMO CPG recommendations has not been systematically *** study assessed ESMO CPG levels of evidence(LOE)and grades of recommendations(GOR),as well as their trends over time across various cancer ***:We manually extracted every recommendation with the Infectious Diseases Society of America(IDSA)classification from each *** examined the distribution of LOE and GOR in all available ESMO CPG guidelines across different topics and cancer ***:Among the 1,823 recommendations in the current CPG,30%were classified as LOEⅠ,and 43%were classified as GOR ***,there was a slight decrease in LOEⅠ(−2%)and an increase in the proportion of GOR A(+1%)in the current CPG compared to previous *** proportion of GOR A recommendations based on higher levels of evidence such as randomized trials(LOEⅠ–Ⅱ)shows a decrease(71%vs.63%,p=0.009)while recommendations based on lower levels of evidence(LOEⅢ–Ⅴ)show an increase(29%vs.37%,p=0.01)between previous and current *** the current versions,the highest proportion of LOEⅠ(42%)was found in recommendations related to pharmacotherapy,while the highest proportion of GOR A recommendations was found in the areas of pathology(50%)and diagnostic(50%)*** variability in LOEⅠand GOR A recommendations and their changes over time was observed across different cancer ***:One-third of the current ESMO CPG recommendations are supported by the highest level of *** well-designed randomized clinical trials are needed to increase the proportion of LOEⅠand GOR A recommendations,ultimately leading to improved outcomes for cancer patients.

关键词： ESMO guidelines Clinical practice guidelines Level of evidence Grade of recommendation

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Role of fullerenols derivative 3HFWC in the treatment of Alzheimer's disease

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Neural Regeneration Research 2024年第8期19卷 1641-1642页

作者： sanja Ivkovic Djuro Koruga Department of Molecular Biology and Endocrinology “VINCA”Institute of Nuclear Sciences-National Institute of Republic of SerbiaUniversity of BelgradeBeogradSrbija TFT Nano Center BelgradeSerbia

Fullerenes:The extensive development of nanoscience that has marked this century continues to evolve,producing new materials,structures,and devices for the treatments of diverse *** are a family of nanoparticles with great applicative promise due to their small size(approximately 1 nm in diameter),structure,and capacity to cross biological barriers.

关键词： treatment evolve size

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Emergency Management in Critical Infrastructures: A Complex-Event-Processing Paradigm

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Journal of Systems Science and Systems Engineering 2019年第1期28卷 37-62页

作者： Vuk mijovic Nikola Tomasevic Valentina Janev Mladen Stanojevic sanja Vranes The mihajlo Pupin Institute University of Belgrade Volgina 1511060 Belgrade Serbia

Critical infrastructures (CI) are difficult to handle due to their complexity, size and the number of stakeholders involved. During emergency situations (e.g. fire or terrorist attack), a CI operator in the control room is faced with a flood of information coming from different sensors and legacy monitoring systems. Since in these situations, time is critical and the operators are under a great deal of pressure, a holistic management of all the technical systems and actors involved is needed, reinforced by the Recommendation and Decision Support System (RDSS) that helps emergency managers to take correct and timely decisions. One way to provide an adequate RDSS support to the operator is proposed in this paper which is based on an intelligent, event driven layer that sits on top of the legacy CI monitoring system. Powered by the complex event processing capabilities and facility data model implemented in the form of CI ontology, this layer processes events originating from different sources, conducts the situation and risk assessment, and reacts accordingly, either automatically or via recommendations proposed to emergency personnel. To validate the proposed approach, an event-driven RDSS was deployed on an airport use case (Nikola Tesla airport in Belgrade), as one of the most complex CIs.

关键词： Emergency management event-driven decision support complex event processing emergency personnel training

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Effects of compost particle size,moisture content and binding agents on co-compost pellet properties

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International Journal of Agricultural and Biological Engineering 2019年第4期12卷 184-191页

作者： Lakshika Hettiarachchi Nilanthi Jayathilake Sudarshana Fernando sanja Gunawardena Department of Chemical and Process Engineering Faculty of EngineeringUniversity of MoratuwaSri Lanka International Water Management Institute P.O.Box 2075ColomboSri Lanka Sri Lanka Council for Agricultural Research Policy No.114/9Wijerama MawathaColombo 07Sri Lanka

Composting is one of the sustainable answers for the management of organic municipal *** nature of loose compost is one of the main drawbacks in promoting compost in agriculture and pelletization of compost can offset these *** this study,the optimum conditions in a die and roller pelletizer to form pellets with desirable properties;bulk density,compressive strength,pellet length and disintegration ability with compost particles of different mesh sizes(2.5,3.5,5 mm),moisture contents(25%,30%,35%,40%,45%),different amounts and types of binding agents(1%,2%,3%by weight of Rice Flour(RF),Lime,Rock Phosphate(RP))were *** increased the bulk density of *** with≤5 mm particles and 25%moisture content resulted pellets with the highest compressive strength and a higher percentage of long ***,the tested properties varied with the type and the amount binding agents used with *** was not observed in pellets free of binding agents during the tested period but binding agents enhanced *** machine efficiency and production efficiency decreased with increased moisture in compost and increased with increased compost particle ***,increased amounts of binding agents in compost reduced the machine *** work shows that compost pelletizing with and without binding agents,enhanced properties of compost required in transportation,storage and application in agriculture.

关键词： binding agents co-compost moisture content particle size pellets compressive strength

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Context dependent song-flight performance and timing in the Black-headed Bunting(Emberiza melanocephala)

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Avian Research 2022年第4期13卷 477-486页

作者： sanja Barisic Davor Cikovic Vesna Tutis Jelena Kralj Herbert Hoi Institute of Ornithology Croatian Academy of Sciences and ArtsZagrebGunduliceva 2410000ZagrebCroatia Konrad Lorenz Institute of Ethology Department of Interdisciplinary Life SciencesUniversity of Veterinary Medicine ViennaSavoyenstraße 1A1160ViennaAustria

Many songbirds produce song-flights;however,the function,vocal and motor characteristics,as well as the diel and seasonal variation of song-flight in songbirds remain not well ***,we studied two types of song-flight in male Black-headed Buntings(Emberiza melanocephala),the Moth—a standard,i.e.,perch song produced during a horizontal flight,and the Towering—a specifically structured song produced during a complex ascending and descending *** perch song,used during Moth flight,has already been described,here we provide the first description and sonogram representation of the more elaborate and less stereotyped Towering *** males started to perform Moth song-flights as soon as they arrived at the breeding site,Towering did not start before the female *** usually delivered spontaneous Moth song-flights before chasing rivals or undertaking aerial fights,suggesting Moth is directed towards conspecific males and serves as a threat ***,playback of conspecific perch songs triggered males to approach the loudspeaker with Moth *** Towering started after females arrived at the breeding site,suggesting the Towering is directed towards conspecific *** detected a seasonal difference in the peak Towering rate between forenoon and afternoon,suggesting that Towerings performed at different times of the day have different *** Towerings were strongly positively related to the number of fertile females at the breeding site,while afternoon Towerings peaked very early in the breeding season and coincided with the number of females at the breeding site before the onset of *** results provide evidence that birds can direct different types of song-flight towards different receivers and suggest the possibility that time of the day determines the context of the display,namely to attract social mates or solicit *** work is needed to account for the effect of between male vari

关键词： Fertilisation probability Mate attraction Moth song-flight Towering song-flight

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Mesalamine treatment mimicking relapse in a child with ulcerative colitis

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World Journal of Pediatrics 2014年第4期10卷 371-373页

作者： Iva Hojsak Ana M Pavić sanja Kolaček Referral Center for Pediatric Gastroenterology and Nutrition Children's Hospital ZagrebZagrebCroatia University of Zagreb Medical School ZagrebCroatia

Background:There are reports on mesalamine-induced bloody diarrhea mimicking ulcerative colitis(UC)relapse,mostly in ***:Herein we present a case of a child with UC who developed relapse of hemorrhagic colitis related to ***:A 10-year-old girl developed severe symptoms mimicking UC relapse 3 weeks after introduction of mesalamine *** mesalamine was withdrawn,her symptoms improved,but deteriorated again during the challenge of mesalamine despite concomitant use of ***:This is the fi rst case report on such a young child during the concomitant use of corticosteroids.

关键词： 5-aminosalicylic acid mesalamine ulcerative colitis

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Seasonal dynamics of foliar antioxidative enzymes and total anthocyanins in natural populations of Iris pumila L.

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Journal of Plant Ecology 2010年第1期3卷 59-69页

作者： Ana Vuleta sanja Manitasevic Jovanovic Darka Seslija Branka Tucic Department of Evolutionary Biology Sinisa Stankovic Institute for Biological ResearchBelgradeSerbia Department of Biochemistry Sinisa Stankovic Institute for Biological ResearchBelgradeSerbia

Aims Plants in their natural habitats frequently cope with a multitude of abiotic stresses,such as high light intensity,extreme temperatures and water deficit,which often co-occur during periods of drought,especially in semi-arid and arid *** of plants to stressful environmental conditions usually induce overproduction of reactive oxygen species(ROS)that,as highly toxic derivatives of O_(2),can assault all cell macromolecules,leading to the disruption of cellular homeostasis and,consequently,the uncoupling of major metabolic processes,the photosynthesis and *** order to minimize ROS-mediated cellular damage,plants have evolved highly efficient antioxidative defense systems that include both enzymatic and non-enzymatic *** abiotic stress can also operate as a strong evolutionary force that shapes adaptations in natural plant populations,the aim of this study was to examine the seasonal variation patterns of two distinct antioxidative systems,ROS-scavenging enzymes and anthocyanin pigments,in the leaf tissue of a steppe plant,Iris pumila,as expressed under contrasting light conditions that the species regularly experiences in the *** We selected two natural populations of *** inhabiting the alternative radiation environments in the Deliblato Sands,a sunexposed dune site and a woodland *** specific activity of three antioxidative enzymes,superoxide dismutase(SOD),catalase(CAT)and peroxidase(POD)and the content of total anthocyanins were examined in leaves of *** plants collected from each of the 31 Iris clones(17 in the exposed population and 14 in the shaded population)once during each of the three seasons,spring,summer and autumn in ***,a fully expanded leaf was cut from each clonal plant between 15:00 and 16:00 h,immediately frozen in liquid nitrogen and stored at-70℃until *** Findings Generally,all three antioxidative enzymes were up-regulated in summer-harvested

关键词： SOD CAT POD anthocyanins seasonal variation

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A rare case of enteropathy-associated T-cell lymphoma presenting as acute renal failure

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World Journal of Gastroenterology 2006年第14期12卷 2301-2304页

作者： milena Bakrac Branka Bonaci miodrag Krstic sanja Simic milica Colovic Institute of Hematology Clinical Center of Serbia Serbia Institute of Allergology and Immunology Clinical Center of Serbia Serbia Institute of Gastroenterology Clinical Center of Serbia Serbia Institute of Nephrology Clinical Center of Serbia Serbia

Enteropathy-associated T-cell lymphoma （EATCL） is a high grade, pleomorphic peripheral T-cell lymphoma usually with cytotoxic phenotypes. We describe a first case of patient with EATCL that is remarkable for its fulminant course and invasion of both kidneys manifested as acute renal failure. The patient was a 23 year old woman with a long history of celiac disease. She was presented with acute renal failure and enlarged mononuclear infiltrated kidneys. Diagnosis of tubuloi-nterstitial nephritis and polyserositis was confirmed with consecutive pulse doses of steroid therapy. After reco-very, she had disseminated disease two months later. Magnetic resonance imaging showed thickened intestine wall, extremely augmented kidneys, enlarged intra-abdominal lymph nodes with extra-luminal compression of common bile duct. Laparotomy with mesenterial adipous tissue and lymph glands biopsy was done. Consecutive pathophysiological and immunohistochemical analyses confirmed the diagnosis of EATCL： CD45RO＋, CD43＋, CD3＋. The revision of renal pathophysiology sub-stantiated the diagnosis. The patient received chemotherapy, but unfortunately she died manifesting signs of pulmonary embolism caused by tumor cells.

关键词： EATCL Acute renal failure Celiac disease Anti-endomisial antibodies

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