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A comparison of short-term postoperative outcomes including nutritional status between gastrectomy with simultaneous cholecystectomy and gastrectomy only in patients with gastric cancer

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Chinese Journal of Cancer Research 2019年第3期31卷 443-452页

作者： You Na Kim Ji Yeong An Min-Gew Choi Jun ho Lee Tae Sung Sohn Jae Moon bae Sung Kim Department of Surgery Samsung Medical CenterSungkyunkwan University School of MedicineSeoul 06351Korea Department of Surgery Korea University Anam HospitalKorea University School of MedicineSeoul 02841Korea

Objective: We aimed to evaluate the effect of simultaneous cholecystectomy on the short-term postoperative outcomes and nutritional status in patients with gastric ***: We retrospectively reviewed data from 4,820 patients with gastric cancer who underwent gastrectomy from January 2011 to December 2016. Patients who underwent only gastrectomy(N=4,578) were matched to those who underwent simultaneous cholecystectomy during gastrectomy(N=242) at a 1:1 ratio using propensity score matching analysis. The nutritional status and inflammatory responses preoperatively and postoperatively and postoperative outcomes were compared between the ***: The simultaneous cholecystectomy group showed more intraoperative blood loss and a longer operative time than the gastrectomy only group [150.0(100.0, 200.0) m L vs. 100.0(100.0, 200.0) m L, P=0.006;176.0(150.0,210.0) min vs. 155.0(128.0, 188.0) min, Phocyte count, total protein level, albumin level, fasting glucose level,and prognostic nutritional index excluding the cholesterol level were not significantly different between the groups,and their changing patterns were similar. Although the cholesterol level was significantly lower in the simultaneous cholecystectomy group than in the gastrectomy only group at all follow-up points, the mean value of the decreased cholesterol level was within normal ***: In gastric cancer patients with gallbladder disease, simultaneous cholecystectomy is safe and not associated with additional nutritional loss.

关键词： Gastric cancer cholecystectomy nutritional status

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外侧闭合楔形胫骨近端截骨术的远期疗效分析(英文)

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中国矫形外科杂志 2008年第13期16卷 987-991页

作者： Dae Kyung bae Kyung ho Yoon sang Jun Song Myeung Cheol Shin Department of Orthopaedic Surgery School of Medicine Kyung Hee University Seoul Korea

[目的]探讨胫骨近端截骨术治疗原发性胫骨近端骨性关节炎的远期疗效以及最佳的截骨矫正角度。[方法]自1985～1997年，79例（111膝）原发性骨性关节炎患者接受了胫骨近端截骨术。其中男5例（5膝），女74例（106膝）；年龄37～70岁（平均5... 详细信息

[目的]探讨胫骨近端截骨术治疗原发性胫骨近端骨性关节炎的远期疗效以及最佳的截骨矫正角度。[方法]自1985～1997年，79例（111膝）原发性骨性关节炎患者接受了胫骨近端截骨术。其中男5例（5膝），女74例（106膝）；年龄37～70岁（平均55岁）。根据术后胫股角（FTA）分为3组。Ⅰ组61膝FTA〈7°；Ⅱ组23膝FTA7°～9°；Ⅲ组27膝FTA≥10°。所有病例术前、术后按特种外科医院评分系统（HSS）评分。[结果]术后随访2年4个月～14年1个月（平均9年6个月）。术前HSS平均60分，术后1年平均94分，末次随访平均87分。采用2种方法判定手术失败：方法1为需行人工全膝关节置换术者，随访4年和14年手术成功率分别为99％和85％；方法2为需行人工全膝关节置换术者或术后HSS评分〈60分，随访4年和14年手术成功率分别为96．4％和75．1％。[结论]胫骨近端截骨术是治疗单间室骨性关节炎的有效方法，但术后胫股角应矫正到外翻7°以上（范围10°～15°）。

关键词：胫骨截骨术近端

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Analysis of Finger Muscular Forces using a Wearable Hand Exoskeleton System

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Journal of Bionic Engineering 2017年第4期14卷 680-691页

作者： Suin Kim Jeongsoo Lee Joonbum bae Department of Mechanical Engineering UNIST Ulsan Korea

In this paper, the finger muscular forces were estimated and analyzed through the application of inverse dynamics-based static optimization, and a hand exoskeleton system was designed to pull the fingers and measure the dynamics of the hand. To solve the static optimization, a muscular model of the hand flexors was derived. The experimental protocol was devised to analyze finger flexors in order to evaluate spasticity of the clenched fingers; muscular forces were estimated while the flexed fingers were extended by the exoskeleton with external loads applied. To measure the finger joint angles, the hand exoskeleton system was designed using four-bar linkage structure and potentiometers. In addition, the external loads to the fingertips were generated by cable driven actuators and simultaneously measured by loadcells which were located at each phalanx. The ex- periments were performed with a normal person and the muscular forces estimation results were discussed with reference to the physical phenomena.

关键词： hand rehabilitation wearable system bionic exoskeleton musculoskeletal model inverse dynamics static opti-mization

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Measurement of alumina film induced ablation of internal insulator in solid rocket environment

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Defence Technology（防务技术） 2023年第11期29卷 181-192页

作者： Ji-Yeul bae In Sik Hwang Yoongoo Kang Agency for Defense Development 160488th Bukyuseong-streetDaejeonSouth Korea

This study investigates the ablation of internal insulation induced by the deposition of an alumina film with different lateral film speeds.A sub-scale test solid rocket motor(SRM)was designed in an impinging jet configuration to form an alumina film on the sample and to encourage the lateral movement of the film by a high-speed wall *** static fire tests of the test SRM were conducted with six different jet velocities(V_(jet)=100 m/s,150 m/s,200 m/s,268 m/s,330 m/s,and 450 m/s)that indirectly affected the velocity of the wall jet and the deposition rate of alumina *** ablation velocity was deduced from the difference in the sample thickness after a test using a coordinate measuring *** droplet deposition mass flux and wall jet velocity were obtained via two-phase flow simulation with the same jet velocity and effective *** a result,the characteristics of alumina-induced ablation and the changes in ablation with jet velocities were *** area within0.8×jet diameter was focused upon,where the ratio of ablation velocity to incoming alumina mass was constant for each jet velocity,and showed a similarity in jet *** the ablation velocity was increased from 2.05 to 9.98 mm/s with increasing jet velocity,the ratio of the ablation velocity and alumina mass flux decreased from 1.07×10^(-4)to 0.49×10^(-4)m^(3)/kg as Al_(2)O_(3)-C reactions became less efficient with a reduced residence time of the *** the decrease in residence time by the wall jet is more pronounced for slow reactions involved in Al_(2)O_(3)-C reactions,fast reactions in Al_(2)O_(3)-C reactions are less affected and result in a convergence of the volumetric rate of ablation per unit mass of alumina.

关键词： Internal insulation Solid rocket motor Ablation Alumina

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Gastric cancer patients at high-risk of having synchronous cancer

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World Journal of Gastroenterology 2006年第16期12卷 2588-2592页

作者： Jun ho Lee Ja Seong bae Keun Won Ryu Jong Seok Lee Sook Ryun Park Chan Gyoo Kim Myoung Cheorl Kook Il Ju Choi Young Woo Kim Jae-Gahb Park Jae-Moon bae Research Institute & hospital National Cancer Center809 Madul-dongIlsandong-guGoyang-siGyeonggi-do411-769Korea

AIM： To identify patients with a high-risk of having a synchronous cancer among gastric cancer patients. METhoDS： We retrospectively analyzed the prospective gastric cancer database at the National Cancer Center, Korea from December 2000 to December 2004. The clinicopathological characteristics of patients with synchronous cancers and those of patients without synchronous cancers were compared. Multivariate analysis was performed to identify the risk factors for the presence of a synchronous cancer in gastric cancer patients. RESULTS： 111 of 3291 gastric cancer patients （3.4%） registered in the database had a synchronous cancer. Among these 111 patients, 109 had a single synchronous cancer and 2 patients had two synchronous cancers. The most common form of synchronous cancer was colorectal cancer （42 patients, 37.2%） followed by lung cancer （21 patients, 18.6%）. Multivariate analyses revealed that elderly patients with differentiated early gastric cancer have a higher probability of a synchronous cancer. CONCLUSION： Synchronous cancers in gastric cancer patients are not infrequent. The physicians should try to find synchronous cancers in gastric cancer patients, especially in the elderly with a differentiated early gastric

关键词： Synchronous cancer Gastric cancer Colorectal cancer

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Effects of upper lid blepharoplasty on visual quality in patients with lash ptosis and dermatochalasis

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International Journal of Ophthalmology(English edition) 2016年第9期9卷 1320-1324页

作者： Scoung Hyun An sang Wook Jin Yoon Hyung Kwon Won Yeol Ryu Woo Jin Jeong Hee bae Ahn Department of Ophthalmology Dong-A University College of Medicine Busan 602-715 Korea

AIM：To assess the effects of upper lid blepharoplasty on visual ***：Seventy-three eyelids of 39 patients were subjected to upper lid ***- and postoperative contrast sensitivity,visual acuity,vertical palpebral aperture and the degree of lash ptosis were ***：The mean log contrast sensitivities under photopic（P =0.017） and scotopic conditions（P =0.009）were improved after surgery,and these differences were *** degree of lash ptosis was also decreased after blepharoplasty（P〈0.001）.CONCLUSION：In our study,a significant increase in contrast sensitivity was found after *** results suggest that upper lid blepharoplasty can be helpful for improving visual quality.

关键词： blepharoplasty visual quality contrast sensitivity

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Dendritic cell-based immunotherapy for colon cancer using an HLA-A＊0201-restricted cytotoxic T-lymphocyte epitope from tumor-associated antigen 90K

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Cellular & Molecular Immunology 2013年第3期10卷 275-282页

作者： Ji Hee Lee Myong-Suk Park Jun-Eul Hwang sang-Hee Cho Woo-Kyun bae Hyun-Jeong Shim Dae-Eun Kim Ik-Joo Chung Department of Hematology-Oncology Chonnam National University Medical School Gwangju Korea The Brain Korea 21 Project Center for Biomedical Human Resources at Chonnam National University Gwangiu Korea

Tumor-associated antigen 90K is implicated in cell-cell and cell-extracellular matrix adhesion through its interaction with galectin-3 and integrin-β 1 and is highly expressed in malignant tissues, making it a novel target for the development of new immunotherapies. We investigated a potential immunotherapy treatment for colon cancer using 90K-specific cytotoxic T lymphocytes induced by autologous dendritic cells and pulsed with 90K peptides. We selected three peptides （90K3s1, 90K5 and 90K523） that bind to HLA-A＊0201 molecules on the basis of their binding affinity, as determined by a peptide-T2 binding assay. Dendritic cells pulsed with 90K peptides resulted in the efficient generation of mature dendritic cells and exhibited enhanced T-cell stimulation and polarization of naive T cells toward Thl. Dendritic cells pulsed with 90K peptides generated potent cytotoxic T-lymphocytes that lysed T2 cells loaded with each 90K peptide, and 90K＋/HLA-A2＋ colon cancer cell lines, including HCT116 and SW480, in a dose-dependent and HLA-A＊O2Ol-restricted manner. No killing was observed in 90K＋/HLA-A2- DLD1 or 90K-/HLA-A2- K562 cells. Therefore, we believe that cytotoxic T-lymphocytes stimulated by 90K peptide-pulsed dendritic cells naturally recognize the 90K peptide presented by colon cancer cells in the context of HLA-A2, and kill 90K-positive tumor cells. Dendritic cells pulsed with 90K peptides led to the induction of granzyme B and perforin positive CD8＋ T cells against HCT116 and SW480 cells, but not DLD1 cells. In conclusion, 90K-specific cytotoxic T lymphocytes, generated by stimulating T cells with 90K peptide-pulsed dendritic cells, could be useful effector cells for the immunotherapv treatment of colon cancer.

关键词： 9OK colon cancer dendritic cells immunotherapy peptide

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Implanting a preferential solid electrolyte interphase layer over anode electrode of lithium ion batteries for highly enhanced Li^+ diffusion properties

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Journal of Energy Chemistry 2020年第9期29卷 285-292,I0009页

作者： Ye Kyu Kim Yoongon Kim Jaejin bae Hyunwoo Ahn Yuseong Noh Hyunsu Han Won bae Kim Department of Chemical Engineering Pohang University of Science and Technology(POSTECH)Nam-gu 37673PohangSouth Korea

The lithium-ion batteries are recognized as the most promising energy storage system,but it still does not meet the power requirements of electric vehicle batteries owing to low volumetric energy density with the traditional graphite electrode *** this study,we report the development of a novel electrode system fabricated by implantation of a solid electrolyte interphase(SEI)layer on the graphite *** SEI-implanted graphite electrode is made using a lithium bis(trifluoromethanesulfonyl)imide(LiTFSI)-based electrolyte and cycled with a lithium tetrafluoroborate LiBF4-based *** new electrode system shows significantly enhanced electrochemical properties owing to the rapid and efficient diffusion of Li ions through the SEI layer between the electrolyte and *** graphite electrode with its pre-formed SEI layer achieves a reversible capacity of 357 mAh g^-1 at 0.5 C after 50 cycles,which is significantly higher than that of commercial lithium-ion battery systems constructed with LiPF6(312mAh g^-1).The resulting unique electrode system could present a new avenue in SEI research for highperformance lithium-ion batteries.

关键词： SEI layer Graphite Implanting Li ion diffusion LiTFSI LiBF4 Artificial Mobility

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Use of oral contraceptives and risk of pancreatic cancer in women:A recalculated meta-analysis of prospective cohort studies

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World Journal of Gastroenterology 2021年第48期27卷 8374-8377页

作者： Jong-Myon bae Preventive Medicine Jeju National University College of MedicineJeju-si 63243Jeju ProvinceSouth Korea

In a recent systematic review and meta-analysis of observational studies,the author found potential errors in the selection and extraction *** recalculated summary relative risks and the results of a dose-response met... 详细信息

关键词： Pancreas neoplasms Oral contraceptives Risk factor Meta-analysis Risk assessment Systematic review

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Near-infrared fluorescence imaging guided surgery in colorectal surgery

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World Journal of Gastroenterology 2022年第12期28卷 1284-1287页

作者： Sung Uk bae Department of Surgery School of MedicineDongsan Medical CenterKeimyung UniversityDaegu 700-712South Korea

Near infrared fluorescence using indocyanine green is beneficial for visual assessment of blood vessels,blood flow,and tissue perfusion,sentinel lymph node biopsy,lymph node road mapping,identification of the vascular system round the major vessels,and the detection of ureters in order to reduce the risk of iatrogenic ureteral lesions in colorectal surgery.

关键词： Fluorescence Enhanced reality Anastomotic leak Lymph node Anastomosis

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