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Prevalence and risk factors of wound complications after transtibial amputation in patients with diabetic foot

World Journal of Diabetes 2024年第4期15卷 629-637页

作者： Young Uk Park seong hyuk Eim Young Wook seo Department of Orthopedic Surgery Ajou University School of MedicineAjou University HospitalSuwon 16499South Korea

BACKGROUND Diabetic foot(DMF)complications are common and are increasing in *** factors related to wound complications are yet to be established after transtibial amputation under the diagnosis of DMF *** To analyze the prognosis and risk factors related to wound complications after transtibial amputation in patients with *** This retrospective cohort study included seventy-two patients with DMF complications who underwent transtibial amputation between April 2014 and March *** groups were categorized based on the occurrence of wound complications,and we compared demographic data between the complication group and the non-complication group to analyze risk ***,a multivariate logistic regression analysis was performed to identify risk *** The average follow-up period was 36.2 *** the 72 cases,31(43.1%)had wound *** these,12 cases(16.7%)received further treatment,such as debridement,soft tissue stump revision,and re-amputation at the proximal *** a group that required further management due to wound complications after transtibial amputation,the hemoglobin A1c(HbA1c)level was 9.32,while the other group that did not require any treatment had a 7.54 HbA1c *** prevalence of a history of kidney transplantation with wound complications after transtibial amputation surgery in DMF patients was significantly greater than in cases without wound complications(P=0.02).Other factors did not show significant *** Approximately 43.1%of the patients with transtibial amputation surgery experienced wound complications,and 16.7%required additional surgical *** HbA1c levels and kidney transplant history are risk factors for postoperative wound complications.

关键词： Diabetic foot Transtibial amputation Wound complications Risk factor

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Crystallographically vacancy‐induced MOF nanosheet as rational single‐atom support for accelerating CO_(2)electroreduction to CO

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Carbon Energy 2024年第8期6卷 49-62页

作者： Jin hyuk Cho Joonhee Ma Chaehyeon Lee Jin Wook Lim Youngho Kim Ho Yeon Jang Jaehyun Kim Myung‐gi seo Youngheon Choi Youn Jeong Jang sang Hyun Ahn Ho Won Jang seoin Back Jong‐Lam Lee Soo Young Kim Department of Materials Science and Engineering Korea UniversitySeoulRepublic of Korea Department of Chemical and Biomolecular Engineering Sogang UniversitySeoulRepublic of Korea Department of Materials Science and Engineering Pohang University of Science and Technology(POSTECH)PohangRepublic of Korea Department of Materials Science and Engineering Research Institute of Advanced MaterialsSeoul National UniversitySeoulRepublic of Korea Lotte Chemical R&D Center DaejeonRepublic of Korea Department of Chemical Engineering Hanyang UniversitySeoulRepublic of Korea School of Chemical Engineering and Material Science Chung‐Ang UniversitySeoulRepublic of Korea

To attain a circular carbon economy and resolve CO_(2)electroreduction technology obstacles,single‐atom catalysts(SACs)have emerged as a logical option for electrocatalysis because of their extraordinary catalytic *** SACs,metal–organic frameworks(MOFs)have been recognized as promising support materials because of their exceptional ability to prevent metal *** study shows that atomically dispersed Ni single atoms on a precisely engineered MOF nanosheet display a high Faradaic efficiency of approximately 100%for CO formation in H‐cell and three‐compartment microfluidic flow‐cell reactors and an excellent turnover frequency of 23,699 h−1,validating their intrinsic catalytic *** results suggest that crystallographic variations affect the abundant vacancy sites on the MOF nanosheets,which are linked to the evaporation of Zn‐containing organic linkers during ***,using X‐ray absorption spectroscopy and density functional theory calculations,a comprehensive investigation of the unsaturated atomic coordination environments and the underlying mechanism involving CO^(*)preadsorbed sites as initial states was possible and provided valuable insights.

关键词： 2‐dimensional material carbon dioxide reduction metal-organic frameworks single‐atom catalysts vacancy sites

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Neuroendocrine carcinoma of the stomach:A case report

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World Journal of Gastrointestinal Surgery 2014年第4期6卷 77-79页

作者： sang hyun Kang Kwang hee Kim sang hyuk seo Min Sung An Tae Kwun ha ha Kyung Park Ki Beom Bae Chang Soo Choi sang hun Oh Young Kil Choi Department of Surgery Busan Paik HospitalInje University College of Medicine

Neuroendocrine carcinoma(NEC)is a rare tumor,comprising<1%of stomach cancers.A 55-year-old woman was referred to our hospital with biopsy-proven gastric cancer.A shallow ulcerative lesion was detected in the lesser curvature of the lower *** was suspected to be early gastric cancerⅡA+ⅡC ***,endoscopic submucosal dissection was *** was subsequently diagnosed with NEC,which is aggressive and carries a poor *** conducted a radical resection and a laparoscopic-assisted distal *** tumor had infiltrated the subserosal layer and6/42 lymph nodes were *** mitotic index was16/10 high power fields and the Ki-67 labeling index was 26%-50%.The final diagnosis of NEC was made according to the World health Organization 2010 *** was suspected of having jumping metastasis to the proximal *** patient was treated with an oral anticancer drug(5-flurouracil based drug)for2 *** patient has been followed up for 3 years without recurrence.

关键词： Neuroendocrine carcinoma Mitosis Ki-67 Gastrectomy Prognosis

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Recurrence of gastric cancer in the jejunal stump after radical total gastrectomy

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World Journal of Gastrointestinal Surgery 2014年第4期6卷 74-76页

作者： Jong Han Yoo sang hyuk seo Min Sung An Tae Kwun Ha Kwang Hee Kim Ki Beom Bae Chang Soo Choi sang Hun Oh Young Kil Choi Department of Surgery Busan Paik HospitalInje University College of Medicine

This is a very rare case of the recurrence of gastric cancer in the jejunal stump after radical total gastrectomy with Roux-en-Y *** January 2008,a 65-year-old man underwent radical total gastrectomy with Roux-en-Y reconstruction for stageⅠB gastric cancer of the upper *** a follow-up in December2011,the patient had a recurrence of gastric cancer on gastroduodenal *** gastroduodenal fibroscopic biopsy specimens show a well-differentiated tubular *** tomography showed no lymphadenopathy or hepatic *** laparotomy,there was a tumor in the jejunal stump involving the pancreatic tail and ***,the patient underwent jejunal pouch resection,distal pancreatectomy and *** patient was diagnosed with gastric cancer on histopathological examination.

关键词： Gastric cancer Recurrence Jejunal stump

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Comparison of sequential and 7-,10-,14-d triple therapy for Helicobacter pylori infection

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World Journal of Gastroenterology 2012年第19期18卷 2377-2382页

作者： hyuk Soon Choi Hoon Jai Chun sang Hoon Park Bora Keum Yeon seok seo Yong Sik Kim Yoon-Tae Jeen Soon Ho Um Hong Sik Lee Chang Duck Kim Ho sang Ryu Division of Gastroenterology and Hepatology Department of Internal MedicineInstitute of Digestive Disease and NutritionKorea University College of MedicineSeoul 136-705South Korea

AIM:To compare the effectiveness of sequential therapy for Helicobacter pylori(***) infection with that of triple therapy of varying ***:The 460 patients enrolled in this study had ***-associated gastritis or a gastric or duodenal *** screening,***-infected patients were randomly assigned to receive either conventional triple therapy for 7,10 or 14 d,or a new 10-d sequential *** of the 4 treatment groups included 115 *** outcomes of eradication therapy were assessed 4 wk after treatment by the urea breath test and ***:The overall eradication rate was 81.0%,and eradication rates were 75.7% for 7-d conventional triple therapy,81.9% for 10-d conventional triple therapy,84.4% for 14-d conventional triple therapy,and 82.0% for 10-d sequential *** intention-to-treat analysis nor per protocol analysis showed significant differences in eradication rates using sequential therapy or the standard triple therapy(P = 0.416 and P = 0.405,respectively).CONCLUSION:There are no significant differences between 10-d sequential eradication therapy for *** and any duration of standard triple treatment in Korean patients.

关键词： He/icobacter pylori Sequential therapy Triple therapy Gastric ulcer Duodenal ulcer Gastritis

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The brain activation pattern of the medial temporal lobe during chewing gum: a functional MRI study

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Neural Regeneration Research 2017年第5期12卷 812-814页

作者： Youn-Hee Choi Woo hyuk Jang sang-Uk Im Keun-Bae Song Hee-Kyung Lee Han Do Lee You Sung seo Sung Ho Jang Department of Preventive Dentistry School of Dentistry Kyungpook National University Department of Occupational Therapy College of Health Science Kangwon National University Departments of Physical Medicine and Rehabilitation College of Medicine Yeungnam University

The human brain is known to be influenced by environmental stimuli（Feeney et al.,1982;Kaplan,1988）.Therefore,research on the brain activation pattern by external stimuli has been an important topic in neuroscience（Kaplan,1988）.Chewing gum has been known to have a positive effect on cognition,including alertness,attention,cognitive processing speed,

关键词： MRI The brain activation pattern of the medial temporal lobe during chewing gum a functional MRI study

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Statistics of oxidation resistance of Ni-(0-15)Co-(8-15)Cr-(0-5)Mo-(0-10)W-(3-8)Al-(0-5)Ti-(0-10)Ta-0.1C-0.01B superalloys at 1000℃ by compositional variations

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Rare Metals 2020年第8期39卷 918-927页

作者： Si-Jun Park Kyu-hyuk Lee seong-Moon seo Hi-Won Jeong Young-Soo Yoo HeeJin Jang Multi-Material Research Center Gwangju-Jeonnam DivisionKorea Automotive Technology InstituteGwangju 62207Republic of Korea Department of Advanced Materials Engineering Chosun UniversityGwangju 61452Republic of Korea High Temperature Materials Group Korea Institute of Materials ScienceChangwon 51508Republic of Korea Department of Materials Science and Engineering Chosun UniversityGwangju 61452Republic of Korea

The effects of alloying elements(Co,Cr,Mo,W,Al,Ti,and Ta)on the oxidation resistance of Ni-(0-15)Co-(8-15)Cr-(0-5)Mo-(0-10)W-(3-8)Al-(0-5)Ti-(0-10)Ta-0.1 C-0.01 B alloys were *** sample compositions were designed by the Box-Behnken method of design of experiments(DOE).The alloying elements show complicated effects on the mass gain due to oxidation,depending on the alloy *** reduces the mass gain *** other elements except Al do not appear to exert a strong effect on the oxidation rate on average,but their influences are shown clearly in the alloys with a low Al ***,W,and Ta reduce the oxidation rate,while Cr,Mo,and Ti promote *** is the most effective element in reducing the oxidation rate of the alloy with a low Al *** is confirmed that a continuous Al2O3 layer is essentially required for high oxidation *** oxide scale of easily oxidized alloys has various oxides such as NiCr2O4,NiAl2O4,NiO,Cr2O3,CrTaO4,and TiO2.

关键词： High temperature oxidation Alloy composition Ni-based superalloy Oxidation resistance Design of experiments

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Short health scale: A valid measure of health-related quality of life in Korean-speaking patients with inflammatory bowel disease

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World Journal of Gastroenterology 2017年第19期23卷 3530-3537页

作者： Soo-Kyung Park Bong Min Ko Hyeon Jeong Goong Jeong Yeon seo sang hyuk Lee Hae Lim Baek Moon Sung Lee Dong Il Park Division of Gastroenterology Department of Internal Medicine Kangbuk Samsung HospitalSungkyunkwan University School of Medicine Digestive Disease Center and Research Institute Department of Internal Medicine Soonchunhyang University School of Medicine

AIM To evaluate the short health scale(SHS),a new,simple,four-part visual analogue scale questionnaire that is designed to assess the impact of inflammatory bowel disease(IBD)on health-related quality of life(HRQOL),in Korean-speaking patients with *** The SHS was completed by 256 patients with Crohn’s disease(CD)and ulcerative colitis(UC).Individual SHS items were correlated with inflammatory bowel disease questionnaire(IBDQ)dimensions and with disease activity to assess ***-retest reliability,responsiveness and patient or disease characteristics with probable association with high SHS scores were *** Of 256 patients with IBD,139(54.3%)had UC and 117(45.7%)had *** correlation coefficients between SHS questions about"symptom burden","activities of daily living",and"disease-related worry"and their corresponding dimensions in the IBDQ ranged from0.62 to 0.71,compared with correlation coefficients ranging from-0.45 to-0.61 for their non-corresponding *** was a stepwise increase in SHS scores,with increasing disease activity in both CD and UC(all P values<0.001).Reliability was confirmed with test-retest correlations ranging from 0.68 to 0.90(all P values<0.001).Responsiveness was confirmed with the patients who remained in *** SHS scores remained unchanged,except for the SHS dimension"disease-related worry".In the multivariate analysis,female sex was associated with worse"general well-being"(OR=2.28,95%CI:1.02-5.08)along with worse disease *** The SHS is a valid and reliable measure of HRQOL in Korean-speaking patients with IBD.

关键词： Quality of life Inflammatory bowel disease Ulcerative colitis Crohn's disease Disease activity

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Sensitivity analysis of influencing parameters on slit-type barrier performance against debris flow using 3D-based numerical approach

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International Journal of Sediment Research 2021年第1期36卷 50-62页

作者： Minseop Kim Seungrae Lee Tae-hyuk Kwon Shin-Kyu Choi Jun-seo Jeon Department of Civil and Environmental Engineering KAIST Building Safety Research Center & Seismic Safety Research Center KICT

Extreme rainfall-induced debris flow can be catastrophic to an urban area,and installation of slit-type barriers can prevent such damage while minimizing negative impact on ***,the performance of slit-type barriers against debris flows remains poorly identified partly due to the innate complexity in interactions between debris flow and solid *** paper investigated the flow behaviors of debris affected by slit-type barriers using the computational fluid dynamics(CFD) method,in which the numerical model based on the volume of fluid method was verified using the physical modeling *** sensitivity analysis was performed by building metamodels to determine the prima ry parameters influencing the barrier performance against debris flows among various variables,in which the effect of input properties and design parameters,particularly the soil concentration in fluidized debris,initial velocity and volume of debris,the barrier height,and the opening ratio,was evaluated from the perspectives of the flow energy reduction and debris *** initial velocity and volume of debris were found to play a significant role in determining the debris flow characteristics.A decrease in the opening ratio in the channel primarily facilitated the energy reduction and trapping due to the reduced opening ***,the barrier height exhibited a limited effect when the height was sufficiently high to block the debris flow *** addition,it was observed that the double barrier system effectively increased the energy reduction while keeping the benefit of open-type *** developed simulation method and obtained results provide an effective tool and an insight that can contribute to an optimum design of the debris-flow barrier.

关键词： Debris flow Slit-type barrier Numerical simulations Sensitivity analysis Mitigation effect

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Endoscopic submucosal tunnel dissection salvage technique for ulcerative early gastric cancer

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World Journal of Gastroenterology 2014年第27期20卷 9210-9214页

作者： hyuk Soon Choi Hoon Jai Chun Min Ho seo Eun Sun Kim Bora Keum Yeon seok seo Yoon Tae Jeen Hong Sik Lee Soon Ho Um Chang Duck Kim Ho sang Ryu Division of Gastroenterology and Hepatology Department of Internal MedicineInstitute of Digestive Disease and NutritionKorea University College of Medicine

Endoscopic submucosal dissection is an effective treatment modality for early gastric cancer(EGC), though the submucosal fibrosis found in ulcerative EGC is an obstacle for successful treatment. This report presents two cases of ulcerative EGC in two males, 73- and 80-year-old, with severe fibrosis. As endoscopic ultrasonography suggested that the EGCs had invaded the submucosal layer, the endoscopic submucosal tunnel dissection salvage technique was utilized for complete resection of the lesions. Although surgical gastrectomy was originally scheduled, the two patients had severe coronary heart disease, and surgeries were refused because of the risks associated with their heart conditions. The endoscopic submucosal tunnel dissection salvage technique procedures described in these cases were performed under conscious sedation, and were completed within 30 min. The complete en bloc resection of EGC using endoscopic submucosal tunnel dissection salvage technique was possible with a free resection margin, and no other complications were noted during the procedure. This is the first known report concerning the use of the endoscopic submucosal tunnel dissection salvage technique salvage technique for treatment of ulcerative EGC. We demonstrate that endoscopic submucosal tunnel dissection salvage technique it is a feasible method showing several advantages over endoscopic submucosal dissection for cases of EGC with fibrosis.

关键词： Endoscopy Early gastric cancer Endoscopic submucosal dissection Endoscopic submucosal tunnel dissection Fibrosis

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