检索结果-南通市图书馆

Benidipine has effects similar to losartan on the central blood pressure and arterial stiffness in mild to moderate essential hypertension

引用

Chinese Medical Journal 2013年第11期126卷 2021-2028页

作者： sang-Hyun Ihm Hui-Kyung Jeon Shung Chull Chae Do-Sun Lim Kee-Sik Kim Dong-Ju Choi Jong-Won Ha Dong-Soo Kim Kye Hun Kim Myeong-Chan Cho sang hong baek Division of Cardiology College of Medicine The Catholic University of Korea Seoul Republic of Korea Jeon HK and baek SH) Department of Internal Medicine Kyungpook National University Hospital Daegu Republic of Korea Division of Cardiology Korea University Anam Hospital SeoulRepublic of Korea Division of Cardioiogy Daegu Catholic University Medical Center Daegu Republic of Korea Division of Cardiology Seoul National University Bundang Hospital Seongnam Republic of Korea Cardiology Division Yonsei Cardiovascular Center Yonsei University College of Medicine Seoul Republic of Korea Division of Cardiology Inje University College of Medicine Busan Paik Hospital Busan Republic of Korea Heart Research Center of Chonnam National University Hospital Gwangju Republic of Korea Department of Internal Medicine Chungbuk National University Hosoital. Cheon~iu. Republic of Korea

Background Central blood pressure （BP） is pathophysiologically more important than peripheral BP for the pathogenesis of cardiovascular disease. Arterial stiffness is also a good predictor of cardiovascular morbidity and mortality. The effects of benidipine, a unique dual L-IT-type calcium channel blocker, on central BP have not been reported. This study aimed to compare the effect of benidipine and Iosartan on the central BP and arterial stiffness in mild to moderate essential hypertensives. Methods This 24 weeks, multi-center, open label, randomized, active drug comparative, parallel group study was designed as a non-inferiority study. The eligible patients （n=200） were randomly assigned to receive benidipine （n=101） or Iosartan （n=99）. Radial artery applanation tonometry and pulse wave analysis were used to measure the central BP, pulse wave velocity （PWV） and augmentation index （AIx）. We also measured the metabolic and inflammatory markers. Results After 24 weeks, the central BP decreased significantly from baseline by （16.8±14.0/10.5±9.2） mmHg （1 mmHg =0.133 kPa）（systolic/diastolic BP; P 〈0.001） in benidipine group and （18.9±14.7/12.1±10.2） mmHg （P 〈0.001） in Iosartan group respectively. Both benidipine and Iosartan groups significantly lowered peripheral BP （P 〈0.001） and AIx （P 〈0.05）, but there were no significant differences between the two groups. The mean aortic, brachial and femoral PWV did not change in both groups after 24-week treatment. There were no significant changes of the blood metabolic and inflammatory biomarkers in each group. Conclusion Benidipine is as effective as Iosartan in lowering the central and peripheral BP, and improving arterial stiffness.

关键词： calcium channel blocker central blood pressure hypertension arteries stiffness

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Comparative study of chitosan/fibroin–hydroxyapatite and collagen membranes for guided bone regeneration in rat calvarial defects: micro-computed tomography analysis

引用

International Journal of Oral Science 2014年第2期6卷 87-93页

作者： Jae Min Song sang Hun Shin Yong Deok Kim Jae Yeol Lee Young Jae baek sang Yong Yoon hong Sung Kim Department of Oral and Maxillofacial Surgery School of Dentistry Pusan National University Yangsan Korea Department of Biomaterial Science Pusan National University Miryang Korea

This study aimed to utilize micro-computed tomography （micro-CT） analysis to compare new bone formation in rat calvarial defects using chitosan/fibroin-hydroxyapatite （CFB-HAP） or collagen （Bio-Gide） membranes. Fifty-four （54） rats were studied. A circular bony defect （8 mm diameter） was formed in the centre of the calvaria using a trephine bur. The CFB-HAP membrane was prepared by thermally induced phase separation. In the experimental group （n= 18）, the CFB-HAP membrane was used to cover the bony defect, and in the control group （n= 18）, a resorbable collagen membrane （Bio-Gide） was used. In the negative control group （n= 18）, no membrane was used. In each group, six animals were euthanized at 2, 4 and 8 weeks after surgery. The specimens were then analysed using micro-CT. There were significant differences in bone volume （BV） and bone mineral density （BMD）（P〈O.05） between the negative control group and the membrane groups. However, there were no significant differences between the CFB-HAP group and the collagen group. We concluded that the CFB-HAP membrane has significant potential as a guided bone regeneration （GBR） membrane.

关键词： chitosan/fibroin-hydroxyapatite collagen membrane guided bone regeneration micro-computed tomography rat calva rial defect

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Aluminum doping for optimization of ultrathin and high-k dielectric layer based on SrTiO3

引用

Journal of Materials Science & Technology 2020年第7期42卷 28-37页

作者： Ji-Ye baek Le Thai Duy sang Yeon Lee Hyungtak Seo Department of Energy Systems Research Ajou UniversitySuwon 443-749South Kore Department of Materials Science and Engineering Ajou UniversitySuwon 443-749South Korea

An ultrathin SrTiO3 dielectric layer is optimized through Al doping to solve the problems existing in development of ultra-high-k oxide MOS *** post-deposition annealing,Al doping induces changes in the electronic structure of SrTiO3,thereby effectively reducing leakage current to 80) of ultrathin SrTMO3 MOS *** titanate(SrTiO3) is a high-k material but its bandgap is smaller than that of other oxide dielectrics(e.g.,SiO2,Al2 O3).Consequently,an ultrathin SrTiO3 film may have a high tunneling leakage current,which is not suitable for capacitor-based *** improve the performance of metal-oxide-semiconductor(MOS) capacitors using SrTiO3,an approach based on homogenous and uniform aluminum doping to SrTiO3 through co-sputtering is *** bandgap of a pristine SrTiO3 film showed an increase of 0.5 eV after Al ***,Al doping decreased the leakage current of SrTiO3/Si-based MOS capacitors by more than five orders of magnitude(at the level of nanoampere per square centimeter).Importantly,a dielectric constant of 81.3 and equivalent oxide thickness less than 5 A were achieved in an 8-nm-thick Al-doped SrTiO3 film owing to changes in its crystal structure and conduction band edge electronic ***,the obtained data show the effectiveness of the proposed approach for solving the problems existing in the development of ultra-high-k oxide MOS capacitors.

关键词： Aluminum doping SrTiO3 ultrathin High dielectric constant MOS capacitors

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Solution and Stability of a Cubic Functional Equation

引用

Acta Mathematica Sinica,English Series 2010年第7期26卷 1255-1262页

作者： Kil Woung JUN sang baek LEE Won Gil PARK Department of Mathematics Chungnam National University Department of Mathematics Education College of EducationMokwon University

In this paper, we investigate the general solution and the stability of a cubic functional equation f（x ＋ ny）＋ f（x - ny）＋ f（nx） = n^2 f（x ＋ y）＋ n^2 f（x - y）＋（n^3 - 2n^2 ＋ 2）f（x）,where n ≥ 2 i... 详细信息

关键词： Hyers-Ulam stability cubic functional equation alternative of fixed point

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Establishment of a chicken intestinal organoid culture system to assess deoxynivalenol‑induced damage of the intestinal barrier function

引用

Journal of Animal Science and Biotechnology 2024年第3期15卷 1119-1130页

作者： Tae hong Kang sang In Lee Department of Animal Science and Biotechnology Kyungpook National UniversitySangjuGyeong‑Sangbuk‑Do 37224Republic of Korea Research Institute for Innovative Animal Science Kyungpook National University37224SangjuGyeong‑Sangbuk‑DoRepublic of Korea

Background Deoxynivalenol(DON)is a mycotoxin that has received recognition worldwide because of its ability to cause growth delay,nutrient malabsorption,weight loss,emesis,and a reduction of feed intake in *** DON-contaminated feedstuff is absorbed in the gastrointestinal tract,we used chicken organoids to assess the DON-induced dysfunction of the small *** We established a culture system using chicken organoids and characterized the organoids at passages 1 and *** confirmed the mRNA expression levels of various cell markers in the organoids,such as KI67,leucine-rich repeat containing G protein-coupled receptor 5(Lgr5),mucin 2(MUC2),chromogranin A(CHGA),cytokeratin 19(CK19),lysozyme(LYZ),and microtubule-associated doublecortin-like kinase 1(DCLK1),and compared the results to those of the small *** results showed that the organoids displayed functional similarities in permeability compared to the small *** damaged the tight junctions of the organoids,which resulted in increased *** Our organoid culture displayed topological,genetic,and functional similarities with the small intes-tine *** on these similarities,we confirmed that DON causes small intestine *** organoids offer a practical model for the research of harmful substances.

关键词： Barrier function Deoxynivalenol Organoids

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Privacy-Preserving Data Publishing for Multiple Numerical Sensitive Attributes

引用

Tsinghua Science and Technology 2015年第3期20卷 246-254页

作者： Qinghai Liu hong Shen Yingpeng sang School of Computer and Information Technology Beijing Jiaotong University School of Information Science and Technology Sun Yat-sen University School of Computer Science University of Adelaide

Anonymized data publication has received considerable attention from the research community in recent years. For numerical sensitive attributes, most of the existing privacy-preserving data publishing techniques concentrate on microdata with multiple categorical sensitive attributes or only one numerical sensitive attribute. However, many real-world applications can contain multiple numerical sensitive attributes. Directly applying the existing privacy-preserving techniques for single-numerical-sensitive-attribute and multiple-categorical-sensitive- attributes often causes unexpected disclosure of private information. These techniques are particularly prone to the proximity breach, which is a privacy threat specific to numerical sensitive attributes in data publication, in this paper, we propose a privacy-preserving data publishing method, namely MNSACM, which uses the ideas of clustering and Multi-Sensitive Bucketization （MSB） to publish microdata with multiple numerical sensitive attributes. We use an example to show the effectiveness of this method in privacy protection when using multiple numerical sensitive attributes.

关键词： privacy-preserving k-anonymity numerical sensitive attribute clustering Multi-Sensitive Bucketization(MSB)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Artificial intelligence based real-time microcirculation analysis system for laparoscopic colorectal surgery

引用

World Journal of Gastroenterology 2020年第44期26卷 6945-6962页

作者： sang-Ho Park Hee-Min Park Kwang-Ryul baek hong-Min Ahn In Young Lee Gyung Mo Son Department of Electronic Engineering Pusan National UniversityBusan 46241South Korea Department of Surgery Pusan National University Yangsan HospitalGyeongsangnam-do 50612South Korea Department of Medicine Pusan National UniversityGyeongsangnam-do 50612South Korea Department of Surgery Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and TechnologyPusan National University Yangsan HospitalYangsan-si 50612South Korea

BACKGROUND Colonic perfusion status can be assessed easily by indocyanine green(ICG)angiography to predict ischemia related anastomotic complications during laparoscopic colorectal ***,various parameter-based perfusion analysis have been studied for quantitative evaluation,but the analysis results differ depending on the use of quantitative parameters due to differences in vascular anatomical ***,it can help improve the accuracy and consistency by artificial intelligence(AI)based real-time analysis microperfusion(AIRAM).AIM To evaluate the feasibility of AIRAM to predict the risk of anastomotic complication in the patient with laparoscopic colorectal cancer *** The ICG curve was extracted from the region of interest(ROI)set in the ICG fluorescence video of the laparoscopic colorectal ***-processing was performed to reduce AI performance degradation caused by external environment such as background,light source reflection,and camera shaking using MATLAB 2019 on an I7-8700k Intel central processing unit(CPU)*** learning and evaluation were performed by dividing into a training patient group(n=50)and a test patient group(n=15).Training ICG curve data sets were classified and machine learned into 25 ICG curve patterns using a self-organizing map(SOM)*** predictive reliability of anastomotic complications in a trained SOM network is verified using test *** AI-based risk and the conventional quantitative parameters including T1/2max,time ratio(TR),and rising slope(RS)were consistent when colonic perfusion was favorable as steep increasing ICG curve *** the ICG graph pattern showed stepped rise,the accuracy of conventional quantitative parameters decreased,but the AI-based classification maintained accuracy *** receiver operating characteristic curves for conventional parameters and AI-based classification were comparable for predicting the anastomotic complication *** pe

关键词： Indocyanine green Laparoscopic Artificial intelligent Anastomotic complications Colorectal surgery Microcirculation analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Principal basis analysis in sparse representation

引用

Science China(Information Sciences) 2017年第2期60卷 199-201页

作者： hong SUN Chengwei sang Chenguang LIU School of electronic Information Wuhan University Department Signal and Image Processing Telecom ParisTech Department of Scientific Research Air Force Early Warning Academy

We propose a principal basis analysis(PBA)method over a learned overcomplete basis set(called dictionary).The proposed PBA makes use of a novel criterion:the frequency of basis vector(atom of the dictionary)over a data *** proposed criterion is well adapted to sparse signal *** it adapts to an intrinsic characteristic of the regularity of signals.

关键词： PSNR Figure PBA SAR

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Work up for the clopidogrel hypersensitivity that led to recognising the undi- agnosed myelodysplastic syndrome

引用

Journal of Geriatric Cardiology 2016年第3期13卷 274-276页

作者： Yoo sang baek Jung Woo Lee Jiehyun Jeon Department of Dermatology College of Medicine Korea University Seoul South Korea

Antiplatelet therapy with clopidogrel is widely used as a preventive strategy in patients with acute coronary syn- drome, particularly after stent *** mani- festations of clopidogrel hypersensitivity reaction have been reported including cutaneous,and hematologic symp- toms[31 as well as fatal reactions including thrombotic throm- bocytopenic purpura （TTP）.

关键词： Clopidogrel Hypersensitivity Myelodysplastic syndrome

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Adaptive Controller Design for Dynamic Maneuvers of High Speed Underwater Vehicles

引用

China Ocean Engineering 2022年第2期36卷 311-321页

作者： Bui Duc hong PHUC Sam-sang YOU Phuc Thinh DOAN sang-Do LEE Department of Mechanical Engineering The University of TulsaTulsaOK 74104USA Division of Mechanical Engineering Korea Maritime and Ocean UniversityBusan 49112Republic of Korea Institute of Interdisciplinary Social Sciences Nguyen Tat Thanh UniversityHo Chi Minh CityVietnam Division of Navigation and Information System Mokpo National Maritime UniversityMokpoJeollanam-do 58628Republic of Korea

The control synthesis of the high-speed underwater vehicle faces many technical challenges due to its inherent structure and surrounding operational *** this paper,the dynamical behavior is firstly described through a bifurcation analysis to give some insights for robust control *** a novel adaptive fractional-order sliding mode controller(AFOSMC)is realized to effectively manipulate the supercavitating vehicle against payload changes,nonlinear planing force,and external *** fractional order(FO)calculus can offer more flexibility and more freedom for tuning active control synthesis than the integer-order *** addition,the adaptation law has been presented to directly handle the payload change *** stability of the controlled vehicle system is proven via Lyapunov stability ***,the dynamic performance of the proposed controller is verified through extensive simulation results,which demonstrate the control accuracy with faster responses compared with existing integer-order ***,the proposed fractional order controllers can provide higher performance than their integer order counterparts with control algorithms.

关键词： fractional order calculus supercavitating underwater vehicles planing force payload change adaptive sliding mode control

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：