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High Voltage 2022年第4期7卷 652-665页

作者： Simone Vincenzo Suraci sandrine Amat Lea Hippolyte Astrid Malechaux Davide Fabiani Claire Le Gall Océane Juan Nathalie Dupuy LIMES Department of ElectricalElectronic and Information EngineeringUniversity of BolognaBolognaItaly Aix Marseille University Avignon UniversitéCNRSMarseilleFrance Institut de Radioprotection et de Sûreté Nucléaire MarseilleFrance

The evolution of properties of crosslinked polyethylene(XLPE)-based insulating mate-rials under radio-chemical ageing conditions is presented and *** total,seven different polymer compounds were tested,characterised by an increasing quantity of additives,for example,antioxidants(AOs)and fillers as flame *** were analysed using different testing techniques,that is,Fourier Transform Infra-Red and dielectric *** allowed a broad characterisation of the polymer,bringing to good correlations between the arising of new chemical groups caused by ageing and the modifications on the complex ***-based AOs are found to be the most efficient in terms of protection against *** the contrary,flame retardants are concluded not to have any impact on the material *** data were then treated using the principal component *** data treatment successfully distinguished the material composition(with and without additives)and the ageing *** results confirm the relevance of this analysis in understanding the impact of irradiation on the chemical and functional properties of the polymer materials studied.

关键词： component principal bringing

A dual function for the chromatin organizer Special A-T rich Binding Protein 1 in B-lineage cells

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Cellular & Molecular Immunology 2023年第10期20卷 1114-1126页

作者： Morgane Thomas Charlotte Bruzeau Ophélie Alyssa Martin Justine Pollet Sébastien Bender Claire Carrion sandrine Le Noir Eric Pinaud Laboratoire Contrôle de la Réponse Immune B et des Lymphoproliférations(CRIBL) Universitéde LimogesCNRS UnitéMixte de Recherche 7276Inserm Unité1262LimogesFrance Centre Hospitalier Universitaire Dupuytren Service d’ImmunopathologieLimogesFrance Centre Hospitalier Universitaire de Limoges Centre National de l’Amylose AL et Autres Maladies par Dépôt d’Immunoglobulines MonoclonalesLimogesFrance Laboratoire Suivi des Therapies Innovantes Institut de Genetique HumaineUMR 9002 CNRS-UMMontpellierFrance

SATB1(Special A-T rich Binding protein 1)is a cell type-specific factor that regulates the genetic network in developing T cells and *** T cells,SATB1 is required for lineage commitment,VDJ recombination,development and *** that its expression varies during B-cell differentiation,the involvement of SATB1 needs to be clarified in this *** a KO mouse model in which SATB1 was deleted from the pro-B-cell stage,we examined the consequences of SATB1 deletion in naive and activated B-cell *** model indicates first,unlike its essential function in T cells,that SATB1 is dispensable for B-cell development and the establishment of a broad IgH ***,we show that SATB1 exhibits an ambivalent function in mature B cells,acting sequentially as a positive and negative regulator of Ig gene transcription in naive and activated cells,***,our study indicates that the negative regulatory function of SATB1 in B cells extends to the germinal center response,in which this factor limits somatic hypermutation of Ig genes.

关键词： B cells Nuclear factor Ambivalent Somatic hypermutation

Concurrent PIEZO1 activation and ATP2B4 blockade effectively reduce the risk of cerebral malaria and inhibit in vitro Plasmodium falciparum multiplication in red blood cells

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Genes & Diseases 2023年第6期10卷 2210-2214页

作者： Mathieu Adjemout Bruno Pouvelle Fatou Thiam Alassane Thiam Magali Torres Samia Nisar Babacar Mbengue Alioune Dieye Pascal Rihet sandrine Marquet Institut National de la SantéEt de la Recherche Médicale(INSERM) UnitéMixte de Recherche(UMR)U1090Aix Marseille UniversitéTAGC Theories and Approaches of Genomic ComplexityInstitut MarMaRaMarseilleFrance Groupe de Recherche Biotechnologie Appliquée et Bioprocédés Environnementaux(GRBA-BE) Ecole Supérieure PolytechniqueUniversitéCheikh Anta Diop de DakarDakar BP5005Senegal Pole D’Immunophysiopathologie&Maladies Infectieuses(IMI) Institut Pasteur de DakarDakar BP 220Senegal Service D’Immunologie UniversitéCheikh Anta Diop de DakarDakar BP5005Senegal Aix Marseille University CNRSMarseille 13009France

Malaria caused by the Plasmodium falciparum parasite is responsible for more than 240 million cases per year and killed 627,000 people in 2020,mostly African *** malaria parasite is transmitted by mosquitos belonging to the genus *** an asymptomatic liver stage,the parasite is released into the bloodstream to invade red blood cells(RBCs)and replicate *** erythrocytic phase is associated with a variety of clinical manifestations,including mild and severe *** malaria(CM)is one of the most severe forms,characterized by the sequestration of parasitized RBCs in the small capillaries of the brain and the local development of cytokine-mediated *** variants in genes encoding proteins involved in red blood cell physiology are protective factors against severe malaria,as clearly demonstrated for the sickle cell variant of hemoglobin(HbS).

关键词： malaria falciparum Plasmodium

A survey of the Szeg? equation Dedicated to Professor Jean-Yves Chemin on the Occasion of His 60th Birthday

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Science China Mathematics 2019年第6期62卷 1087-1100页

作者： Patrick Gérard sandrine Grellier Laboratoire de Mathématiques d'Orsay Université Paris-Sud CNRSUniversité Paris-Saclay Institut Denis Poisson-Université d'Orléans/Université de Tours CNRS UMR

We survey the main properties of the cubic Szeg? equation from the PDE viewpoint, emphasising global existence of smooth solutions, analytic regularity, growth of high Sobolev norms and the effects of weak damping.

关键词： cubic Szego equation integrable system Hankel operator spectral analysis analytic regularity wave turbulence

Selective and taxon-dependent effects of semi-feral cattle grazing on tree regeneration in an old-growth Mediterranean mountain forest

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Forest Ecosystems 2020年第1期7卷 128-140页

作者： Xavier Fortuny Christopher Carcaillet sandrine Chauchard Ecole Pratique des Hautes Etudes(EPHE) PSL University75014 ParisFrance Laboratoire d’ cologie des Hydrosystèmes Naturels et Anthropisés(UMR5023 CNRS UniversitéLyon 1ENTPE)69622 VilleurbanneFrance Universitéde Lorraine AgroParisTechINRAEUMR Silva54000 NancyFrance

Background:In Mediterranean mountain socio-ecosystems,both grazing by livestock and the dry season may influence tree ***,the relative contributions of these drivers are poorly known,even though present and future canopy composition might result from past and present variations in climate and herbivore *** study aims to test how semi-feral cattle presence and season affect tree ***:The study was conducted using permanent plots inside and outside a cattle exclosure in an old-growth Mediterranean *** and seedlings were counted five times per year(winter,early spring,middle spring,summer,fall)and monitored over 7 ***:Semi-feral cattle exclusion increased Acer,Fagus,Ilex,Pinus,Prunus and Quercus sapling densities and increased Acer,Fraxinus,Ilex,Quercus and Sorbus seedling ***,the dry season did not exert any noticeable effects on the sapling or seedling densities of any of the studied ***:Semi-feral cattle presence may limit tree regeneration through taxon-dependent effects,which suggests that the current decrease in grazing livestock across the Mediterranean basin will modify recruitment processes and,likely,future forest ***:Semi-feral cattle presence acts as a selective driver of tree community composition.

关键词： Cattle Climate Experiment Herbivory Forest pastoralism

Effect of micro-algae Schizochytrium *** in plant diet on reproduction of female rainbow trout(Oncorhynchus mykiss):maternal programming impact of progeny

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Journal of Animal Science and Biotechnology 2022年第4期13卷 1175-1192页

作者： Emilie Cardona Emilien Segret Yoann Cachelou Thibaut Vanderesse Laurence Larroquet Alexandre Hermann Anne Surget Geneviève Corraze Frederic Cachelou Julien Bobe sandrine Skiba-Cassy INRAE Univ.Pau&Pays AdourE2S UPPANuMéAF-64310Saint Pée-sur-NivelleFrance INRAE UR1037 Fish Physiology and Genomic laboratoryF-35000 RennesFrance Viviers de Sarrance F-64490SarranceFrance Viviers de Rébénacq F-64260RébénacqFrance.

Background:The broodstock diet,and in particular the lipid and fatty acid composition of the diet,is known to play a key role in reproductive efficiency and survival of the progeny in fish.A major problem when replacing both fish meal and fish oil by plant sources is the lack of n-3 long chain polyunsaturated fatty acids,such as eicosapentaenoic acid(EPA)and docosahexaenoic acid(DHA).To address this problem,we studied the effect of the plant-based diet supplemented with Schizochytrium ***,source of DHA,compared to a conventional commercial diet rich in fish meal and fish oil on reproductive performance and egg quality and the consequences on progeny,in female rainbow trout ***:The results demonstrated that DHA-rich microalgae supplementation in a plant-based diet allowed for the maintenance of reproductive performance and egg quality comparable to a conventional commercial feed rich in fish meal and fish oil and led to an increased significant fry survival after ***,when females were fed a plant-based diet supplemented with micro-algae,the 4-month-old progenies showed a significant higher growth when they were challenged with a similar diet as broodstock during 1 *** provide evidence for metabolic programming in which the maternal dietary induced significant protracted effects on lipid metabolism of ***:The present study demonstrates that supplementation of a plant-based diet with DHA-rich microalgae can be an effective alternative to fish meal and fish oil in rainbow trout broodstock aquafeed.

关键词： Egg quality Micro-algae Nutritional programming Plant diet Rainbow trout Reproduction

A cautionary note on some phylogenetic dissimilarity measures

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Journal of Plant Ecology 2015年第1期8卷 12-16页

作者： Carlo Ricotta Giovanni Bacaro sandrine Pavoine Department of Environmental Biology University of Rome‘La Sapienza’Piazzale Aldo Moro 500185 RomeItaly CNR-IRPI Istituto di Ricerca per la Protezione IdrogeologicaVia Madonna Alta 12606128 PerugiaItaly Department of Life Science BIOCONNETBiodiversity and Conservation NetworkUniversity of SienaVia P.A.Mattioli 453100 SienaItaly Département Ecologie et Gestion de la Biodiversité Muséum National d’Histoire NaturelleUMR 7204 CNRS UPMC55-61 Rue Buffon75005 ParisFrance Department of Zoology Mathematical Ecology Research GroupUniversity of OxfordSouth Parks RoadOxford OX13PSUK

Aims Measures of plot-to-plot phylogenetic dissimilarity and beta diversity are providing a powerful tool for understanding the complex ecolog-ical and evolutionary mechanisms that drive community *** Here,we review the properties of some previously published dis-similarity measures that are based on minimum or average phylo-genetic dissimilarity between species in different *** Findings We first show that some of these measures violate the basic condi-tion that for two identical plots the measures take the value *** also violate the condition that the dissimilarity between two identical plots should always be lower than that between two differ-ent *** erratic behavior renders these measures unsuitable for measuring plot-to-plot phylogenetic *** next pro-pose a new measure that satisfies these conditions,thus providing a more reasonable way for measuring phylogenetic dissimilarity.

关键词： abundance-weighted dissimilarity measures index symmetry patristic distances presence/absence dissimilarity measures nearest-neighbor metrics

Diverse Transcriptional Programs Associated with Environmental Stress and Hormones in the Arabidopsis Receptor-Like Kinase Gene Family

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Molecular Plant 2009年第1期2卷 84-107页

作者： Lee Chae Sylvia Sudat sandrine Dudoit Tong Zhu Sheng Luan Department of Plant and Microbial Biology University of California Berkeley CA 94720 USA Division of Biostatistics School of Public Health University of California Berkeley CA 94720 USA Syngenta Biotechnology Inc. Research Triangle Park NC 27709 USA

The genome ofArabidopsis thaliana encodes more than 600 receptor-like kinase （RLK） genes, by far the dominant class of receptors found in land plants. Although similar to the mammalian receptor tyrosine kinases, plant RLKs are serine/threonine kinases that represent a novel signaling innovation unique to plants and, consequently, an excellent opportunity to understand how extracellular signaling evolved and functions in plants as opposed to animals. RLKs are predicted to be major components of the signaling pathways that allow plants to respond to environmental and developmental conditions. However, breakthroughs in identifying these processes have been limited to only a handful of individual RLKs. Here, we used a Syngenta custom Arabidopsis GeneChip array to compile a detailed profile of the tran- scriptional activity of 604 receptor-like kinase genes after exposure to a cross-section of known signaling factors in plants, including abiotic stresses, biotic stresses, and hormones. In the 68 experiments comprising the study, we found that 582 of the 604 RLK genes displayed a two-fold or greater change in expression to at least one of 12 types of treatments, thereby providing a large body of experimental evidence for targeted functional screens of individual RLK genes. We investigated whether particular subfamilies of RLK genes are responsive to specific types of signals and found that each subfamily displayed broad ranges of expression, as opposed to being targeted towards particular signal classes. Finally, by analyzing the divergence of sequence and gene expression among the RLK subfamilies, we present evidence as to the functional basis for the expansion of the RLKs and how this expansion may have affected conservation and divergences in their function. Taken as a whole, our study represents a preliminary, working model of processes and interactions in which the members of the RLK gene family may be involved, where such information has remained elusive for so many

关键词： Abiotic/environmental stress hormone biology receptors transcriptome analysis disease responses Arabidopsis.

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《隐涵》述介

当代语言学 2022年第3期24卷 468-474页

作者： sandrine Zufferey Jacques Moeschler Anne Reboul 徐永智不详上海交通大学外国语学院

sandrine Zufferey,Jacques Moeschler,Anne Reboul著1. 引言英国哲学家保尔·格赖斯(Herbert Paul Grice)于1967年在哈佛大学威廉·詹姆斯讲坛上提出的隐涵理论可谓一石激起千层浪, 在语言学与语言哲学界引起了巨大反响。隐涵理论突破... 详细信息

sandrine Zufferey,Jacques Moeschler,Anne Reboul著1. 引言英国哲学家保尔·格赖斯(Herbert Paul Grice)于1967年在哈佛大学威廉·詹姆斯讲坛上提出的隐涵理论可谓一石激起千层浪, 在语言学与语言哲学界引起了巨大反响。隐涵理论突破了以往意义研究的局限, 将句子意义与语用(言者)意义剥离开来, 形成了逻辑意义与日常意义的鲜明对照。因此, 它与Austin(1962)、 Searle(1969)的言语行为理论并称为语用学的两块基石。

关键词：句子意义逻辑意义隐涵理论言语行为理论格赖斯 Austin Searle 威廉·詹姆斯

Diet breadth and mortality patterns from Laoya Cave： A primary profile of MIS 3/2 hunting strategies in the Yunnan-Guizhou Plateau, southwest China

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Science China Earth Sciences 2016年第8期59卷 1642-1651页

作者： WANG XiaoMin GUAN Ying CAI HuiYang sandrine COSTAMAGNO ZHANG LiMin XU ChunHua GAO Xing Key Laboratory of Vertebrate Evolution and Human Origins of Chinese Academy of Sciences Institute of Vertebrate Paleontology and Paleoanthropology Chinese Academy of Sciences Beijing 100044 China University of Chinese Academy of Sciences Beijing 100049 China TRACES CNRS Toulouse 31058 France Guizhou Provincial Museum Guiyang 550001 China

Laoya Cave is a long-term occupation site of Late Paleolithic humans in the Yunnan-Guizhou Plateau, southwest China, where abundant lithic, bone materials were recovered. Dating by the AMS technique showed a significant depositional process during marine isotope stage(MIS) 3/2. In this study, the species spectrum was presented from the perspective of zooarchaeology and the mortality profile of large Cervidae was examined to help increase our understanding of the subsistence strategy of local people dealing with climate and environmental changes. The main part of the diet was focused on large Cervidae, and the dominance of Ungulates indicates effective management of the cave and local fauna. On the other hand, the mortality profiles of large Cervidae varied correspondingly with climate change. The evidence indicates a specialized hunting strategy that was also flexible, depending on the prevailing climate and environment.

关键词： Cervidae Late Paleolithic Southwest China MIS 3 Zooarchaeology Survival strategy