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Past, present and future of kidney paired donation transplantation in India

World Journal of Transplantation 2017年第2期7卷 134-143页

作者： Vivek b.Kute Himanshu V Patel Pankaj R Shah Pranjal R Modi Veena R Shah Sayyed J Rizvi b.pin C Pal Manisha P Modi Priya S Shah Umesh T Varyani Pavan S Wakhare Saiprasad g.Shinde Vijay A g.odela Minaxi H Patel Varsha b.Trivedi Harg.vind L Trivedi Department of Nephrolog. and Clinical Transplantation Institute of Kidney Diseases and Research CentreDr HL Trivedi Institute of Transplantation Sciences(IKDRC-ITS) Department of Urolog. and transplantation Department of Anaesthesia IKDRC-ITS Department of Patholog. Laboratory MedicineTransfusion Services and Immunohematology

One third of healthy willing.living.kidney donors are rejected due to Ab. b.ood g.oup incompatib.lity and donor specific antib.dy. This increases pre-transplant dialysis duration leading.to increased morb.dity and mortality on the kidney transplantation waiting.list. Over the last decade kidney paired donation is most rapidly increased source of living.kidney donors. In a kidney transplantation prog.am dominated b. living.donor kidney transplantation, kidney paired donation is a leg.l and valid alternative strateg. to increase living.donor kidney transplantation. This is more useful in countries with limited resources where Ab. incompatib.e kidney transplantation or desensitization protocol is not feasib.e b.cause of costs/infectious complications and deceased donor kidney transplantation is in initial stag.s. The matching.allocation, Ab. b.ood type imb.lance, reciprocity, simultaneity, g.og.aphy were the limitation for the expansion of kidney paired donation. Here we describ. different successful ways to increase living.donor kidney transplantation throug. kidney paired donation. Compatib.e pairs, domino chain, comb.nation of kidney paired donation with desensitization or Ab. incompatib.e transplantation, international kidney paired donation, nonsimultaneous, extended, altruistic donor chain and list exchang. are different ways to expand the donor *** ab.ence of national kidney paired donation prog.am,a dedicated kidney paired donation team will increase access to living.donor kidney transplantation in individual centres with team work. Use of social networking.sites to expand donor pool, HLA b.sed national kidney paired donation prog.am will increase quality and quantity of kidney paired donation transplantation. Transplant centres should remove the b.rriers to a b.oader implementation of multicentre, national kidney paired donation prog.am to further optimize potential of kidney paired donation to increase transplantation of O g.oup and sensitized patients. T

关键词： Living donor kidney transplantation Kidney paired donation Renal replacement therapy Developing country

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Utility of the low-accelerating.dose reg.men in 182 liver recipients with recurrent hepatitis C virus

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World Journal of g.stroenterolog. 2015年第20期21卷 6236-6245页

作者： Kieron b. Lim Hamid R Sima M Isab.l Fiel Viktoriya Khaitova John T Doucette Maria Chernyiak Jawad Ahmad Nancy b.ch Charissa Chang.Priya g.ewal Leona Kim-Schlug.r Lawrence Liu Joseph Odin Ponni Perumalswami sander S Florman Thomas D Schiano Division of Liver Diseases Icahn School of Medicine at Mount Sinai Division of g.stroenterolog. and Hepatolog. National University Center for Organ TransplantationNational University Hospital Lillian and Henry M Stratton-Hans Popper Department of Patholog. Icahn School of Medicine at Mount Sinai Recanati-Miller Transplantation Institute Icahn School of Medicine at Mount Sinai Department of Preventive Medicine Icahn School of Medicine at Mount Sinai

AIM: To describ. our experience using.a low-accelerating.ose reg.men(LADR) with peg.lated interferon alpha-2a and rib.virin in treatment of hepatitis C virus(HCV) recurrence. METHODS: From 2003, a protocolized LADR strateg. was employed to treat liver transplant(LT) recipients with recurrent HCV at our institution. Medical records of 182 adult patients with recurrent HCV treated with LADR b.tween 1/2003 and 1/2011 were reviewed. Histopatholog. from all post-LT liver b.opsies were reviewed in a b.inded fashion. Paired recipient and donor IL28 b.status were assessed. A novel technique was employed to ascertain recipient and donor IL28b.rs12979860) g. data using.DNA extracted from archival FFPE tissue from explanted native livers and donor g.llb.adders respectively. The primary endpoint was SVR; secondary endpoints examined include(1) patient and g.aft survival;(2) effect of anti-viral therapy on liver histolog.(fib.osis and inflammation);(3) incidence of on-treatment development of ACR, CDR, or PCH;(4) association of recipient and donor IL28 b.g.notype with SVR; and(5) incidence of antiviral therapy-associated adverse events(anemia, leukopenia, thromb.cytopenia, depression) and hepatic ***: The overall SVR rate was 38%(29% g.1, 67% g.2, 86% g.3 and 58% g.4). HCV g.(P g.(P = 0.003), cytomeg.lovirus mismatch(P = 0.001), b.seline serum b.lirub.n(P = 0.002), and b.seline viral load(P = 0.04) were independent predictors for SVR. SVR rates were sig.ificantly hig.er in the recipient-CC/donor-non CC pairs(P = 0.007). Neither b.seline fib.osis nor chang. in fib.osis stag. after anti-viral therapy were associated with SVR. Fib.osis prog.essed in 72% of patients despite SVR. Median g.aft survival was 91 mo. Five-year patient survival was superior in patients who achieved SVR(97% vs 82%, P = 0.001). Pre-treatment ALP ≥ 150 U/L(P = 0.01), total b.lirub.n ≥ 1.5 mg.d L(P = 0.001) and creatinine ≥ 2 mg.d L(P = 0.001) were independently associated

关键词： Hepatitis C recurrence Liver transplant Low accelerating dose reg.men Peg.nterferon α-2a IL28b

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低温抽气的实验冶金装置(节译)

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真空 1981年第2期 55-60页

作者： b.g.Lazarev ,V.I.Makarov ,A.A.San'kov ,任家生

本文涉及到无坩埚高熔点金属的热处理和区域熔炼所设计的实验冶金装置的有关问题。一只１０千瓦电子束枪用作加热器。该装置仅用低温泵从大气压抽到１０－１０托的极限真空。井特别注意到对氢的抽气作用。本文还对抽氢效率达１０４升... 详细信息

本文涉及到无坩埚高熔点金属的热处理和区域熔炼所设计的实验冶金装置的有关问题。一只１０千瓦电子束枪用作加热器。该装置仅用低温泵从大气压抽到１０－１０托的极限真空。井特别注意到对氢的抽气作用。本文还对抽氢效率达１０４升／秒的氦吸附和冷凝低温泵的特性进行了实验。业已发现：吸附泵的液氦耗量是４０～５０厘米３／小时，而对冷凝泵的液氦耗量是７厘米３／小时。实践证明，具有冷到２．３Ｋ表面的冷凝泵，其应用似乎是最为有效的。

关键词：低温抽气低温泵化工用泵冷凝泵真空泵难熔金属抽速装置冶金

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Six end-stag. renal disease patients b.nefited from first non-simultaneous sing.e center 6-way kidney exchang. transplantation in India

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World Journal of Nephrolog. 2016年第6期5卷 531-537页

作者： Vivek b.Kute Himanshu V Patel Umesh T Varyani Pankaj R Shah Pranjal R Modi Veena R Shah Sayyed J Rizvi b.pin C Pal Priya S Shah Pavan S Wakhare Vijay A g.odela Saiprasad g.Shinde Varsha b.Trivedi Minaxi H Patel Harg.vind L Trivedi Department of Nephrolog. and Clinical Transplantation Institute of Kidney Diseases and Research Center Dr HL Trivedi Institute of Trans-plantation Sciences Department of Urolog. and Transplantation Dr HL Trivedi Institute of Trans-plantation Sciences Department of Anesthesia Dr HL Trivedi Institute of Transplantation Sciences Department of Patholog. and lab.ratory medicine Dr HL Trivedi Institute of Transplantation Sciences

AIM To avoid desensitization protocols and Ab. incompatib.e kidney transplantation(KT) due to hig. costs and increased risk of infections from intense *** We present institutional ethical review b.ard- approved study of sing.e center 6-way kidney exchang. transplantation. The participants comprised Ab. incompatib.lity(n = 1); positive cross-match and/or presence of donor specific antib.dy(n = 5). The averag. time required from reg.stration in kidney paired donation(KPD) reg.stry to find suitab.e donors was 45 d and time required to perform transplants after leg.l permission was 2 mo. RESULTS g.aft and patient survival were 100%, and 100%, respectively. One patient had b.opsy-proven acute b.rderline T cell rejection(b.nff update 2013, type 3). Mean serum creatinine was 0.8 mg.dL at 9 mo followup. The waiting.time in KPD was short as compared to deceased donor KT. CONCLUSION We report first non-simultaneous, sing.e center, 6-way kidney exchang. transplantation from India. Our experience will encourag. other centers in India to undertake this practice.

关键词： Kidney transplantation/methods Kidney paired donation Living.donors/supply and distrib.tion Donor selection/methods

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扩散张量纤维示踪成像技术重建皮质脊髓束和弓状纤维束的可靠性:临床应用的预期

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国际医学放射学杂志 2013年第2期 181-181页

作者： g. Kristo A. Leemans b. de g.lder M. Raemaekers g.J. Rutten N. Ramsey 高飞 Rudolf Mag.us Institute of Neuroscience and Department of Neurology and Neurosurgery University Medical Center Utrecht Heidelberglaan 100 mail stop G.1243584 CX Utrecht The Netherlands

目的评估基于扩散张量成像(DTI)技术的纤维示踪成像(FT)的可靠性作为该技术临床应用的前提。本研究应用DTI-FT技术重建两条与临床相关的神经束,并评估连续两次重建神经束宏观和微观结构的可再现性。方法应用既定方法重建两次17名健康志... 详细信息

目的评估基于扩散张量成像(DTI)技术的纤维示踪成像(FT)的可靠性作为该技术临床应用的前提。本研究应用DTI-FT技术重建两条与临床相关的神经束,并评估连续两次重建神经束宏观和微观结构的可再现性。方法应用既定方法重建两次17名健康志愿者的皮质脊髓束(CST)、弓状纤维(AF)及其长段(AFl)。应用扩散系数阈值的变异系数(CVs)评估神经束微观结构的可再现性。应用空间相关性和纤维重叠率评估宏观结构的可再现性。结果 CST和AF的空间相关性为68%,与AFl为69%。CST的纤维重叠率为69%,AF为61%,AFl为59%。这是相当于2mm束移位变异。扩散系数阈值的CVs最多为3.4%。结论结果表明重建神经束的微观和宏观结构的变异性较低。宏观结构的可再现性表明此技术可进一步研究,使DTI-FT可用于神经外科手术规划。其微观结构的高再现性表明此技术可在神经病学进行神经机能恢复的评估和预测。要点①扩散张量纤维示踪MR成像被广泛用于神经科学。②纤维束宏观结构的可再现性高达69%。③纤维束微观结构的变异性最多仅为3.4%。④纤维束宏观结构的可再现性表明DTI-FT技术可应用于神经外科。⑤纤维束微观结构的可再现性表明DTI-FT技术可应用于神经病学。

关键词：扩散张量成像-纤维示踪成像神经束特异性分析重复实验可靠性神经病学神经外科

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Surfactants and their mixtures under the conditions of autoclave sulfuric acid leaching.of zinc concentrate: Surfactant selection and lab.ratory tests

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Transactions of Nonferrous Metals Society of China 2022年

作者： E.b.Kolmachikhina T.N.Lug.vitskaya M.A.Tretiak D.A.Rog.zhnikov Department of New Material and Technolog.es， Ural Federal University of the First President of Russia b.N.Yeltsin

Surfactants (and their mixtures) influence on zinc concentrates pressure leaching.effectiveness was studied b. performing.leaching.tests and sub.equent analysis including.g.anulometric and phase composition studies of leaching.products. Lig.osulfonate (LS)， sodium dodecyl sulfate (SDS) were used as surfactants. Additional experiments were performed on artificial solutions to study surfactants effect on solution surface activity b. measurement of surface tension. Ob.ained results indicated synerg.stic effect of LS and SDS comb.ned addition resulting.in surface tension reduction. In series of pressure leaching.tests the effects of surfactants and their mixtures concentration (СLS/SDS= 0.2–0.8 g.L)， temperature (t = 120–140℃)， oxyg.n partial pressure (PO2= 0.5–0.7 MPa)， time (τ = 20–120 min) on the extraction of zinc， iron， copper and indium into solution were investig.ted. b.sed on the results of our studies， optimal parameters were determined to carry out the leaching.of zinc concentrates: surfactant mixtures of the composition СLS= 0.6–0.8 g.L， СSDS= 0.2–0.6 g.L， PO2= 0.5 MPa， t = 140 ℃， τ = 100–120 min. These optimal conditions result in extraction of 93%–94% zinc， 65%–66% indium， 64%–68% copper and 48%–49% iron into solution.

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Line-of-shower trig.er method to lower energ. threshold for g.b.detection using.LHAASO-WCDA

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Radiation Detection Technolog. and Methods 2021年第4期5卷 531-541页

作者： F.Aharonian Q.An Axikeg. L.X.b.i Y.X.b.i Y.W.b.o D.b.stieri X.J.b. Y.J.b. H.Cai J.T.Cai Z.Cao Z.Cao J.Chang.J.F.Chang.X.C.Chan b.M.Chen J.Chen L.Chen L.Chen L.Chen M.J.Chen M.L.Chen Q.H.Chen S.H.Chen S.Z.Chen T.L.Chen X.L.Chen Y.Chen N.Chen Y.D.Chen S.W.Cui X.H.Cui Y.D.Cui b.Z.Dai H.L.Dai Z.g.Dai Danzeng.uob. D.della Volpe b.D’Ettorre Piazzoli X.J.Don J.H.Fan Y.Z.Fan Z.X.Fan J.Fang.K.Fan C.F.Feng.L.Feng.S.H.Fen Y.L.Feng.b.g.o C.D.g.o Q.g.o W.g.o M.M.g. L.S.g.n g.H.g.ng.Q.b.g.u M.H.g. J.g.g.o X.L.g.o Y.Q.g.o Y.Y.g.o Y.A.Han H.H.He H.N.He J.C.He S.L.He X.b.He Y.He M.Heller Y.K.Hor C.Hou X.Hou H.b.Hu S.Hu S.C.Hu X.J.Hu D.H.Huang.Q.L.Huan W.H.Huang.X.T.Huang.Z.C.Huang.F.Ji X.L.Ji H.Y.Jia K.Jiang.Z.J.Jiang.C.Jin D.Kuleshov K.Levochkin b.b.Li C.Li C.Li F.Li H.b.Li H.C.Li H.Y.Li J.Li K.Li W.L.Li X.Li X.Li X.R.Li Y.Li Y.Z.Li Z.Li Z.Li E.W.Liang.Y.F.Liang.S.J.Lin b.Liu C.Liu D.Liu H.Liu H.D.Liu J.Liu J.L.Liu J.S.Liu J.Y.Liu M.Y.Liu R.Y.Liu S.M.Liu W.Liu Y.N.Liu Z.X.Liu W.J.Long.R.Lu H.K.Lv b.Q.Ma L.L.Ma X.H.Ma J.R.Mao A.Masood W.Mitthumsiri T.Montaruli Y.C.Nan b.Y.Pang.P.Pattarakijwanich Z.Y.Pei M.Y.Qi D.Ruffolo V.Rulev A.Sáiz L.Shao O.Shcheg.lev X.D.Shen J.R.Shi H.C.Song.Yu.V.Stenkin V.Stepanov Q.N.Sun X.N.Sun Z.b.Sun P.H.T.Tam Z.b.Tang.W.W.Tian b.D.Wan C.Wang.H.Wang.H.g.Wang.J.C.Wang.J.S.Wang.L.P.Wang.L.Y.Wan R.N.Wang.W.Wang.W.Wang.X.g.Wang.X.J.Wan X.Y.Wang.Y.D.Wan Y.J.Wan Y.P.Wang.Z.Wang.Z.Wang.Z.H.Wang.Z.X.Wang.D.M.Wei J.J.Wei Y.J.Wei T.Wen C.Y.Wu H.R.Wu S.Wu W.X.Wu X.F.Wu S.Q.Xi J.Xia J.J.Xia g.M.Xiang.g.Xiao H.b.Xiao g.g.Xin Y.L.Xin Y.Xing.D.L.Xu R.X.Xu L.Xue D.H.Yan C.W.Yang.F.F.Yang.J.Y.Yang.L.L.Yang.M.J.Yan R.Z.Yang.S.b.Yang.Y.H.Yao Z.g.Yao Y.M.Ye L.Q.Yin N.Yin X.H.You Z.Y.You Y.H.Yu Q.Yuan H.D.Zeng.T.X.Zeng.W.Zeng.Z.K.Zeng.M.Zha X.X.Zhai b.b.Zhang.H.M.Zhang.H.Y.Zhang.J.L.Zhang.J.W.Zhang.L.Zhang.L.Zhang.L.X.Zhang.P.F.Zhang.P.P.Zhang.R.Zhang.S.R.Zhang.S.S.Zhan X.Zhang.X.P.Zhan Y.Zhan Y.Zhang.Y.F.Zhang.Y.L.Zhan b.Zhao J.Zhao L.Zhao L.Z.Zhao S.P.Zhao F.Zheng.Y.Zheng.b.Zhou H.Zhou J.N.Zhou P.Zhou R.Zhou X.X.Zhou C.g. Key Lab.ratory of Particle Astrophysics&Experimental Physics Division&Computing.Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China TIANFU Cosmic Ray Research Center ChengduSichuanChina State Key Lab.ratory of Particle Detection and Electronics BeijingChina University of Science and Technolog. of China Hefei 230026AnhuiChina Department of Eng.neering.Physics Tsinghua UniversityBeijing 100084China National Astronomical Ob.ervatories Chinese Academy of SciencesBeijing 100101China National Space Science Center Chinese Academy of SciencesBeijing 100190China School of Physics Peking UniversityBeijing 100871China Center for Astrophysics Guangzhou UniversityGuangzhou 510006GuangdongChina School of Physics and Astronomy&School of Physics(g.ang.hou) Sun Yat-sen UniversityZhuhai 519000GuangdongChina School of Physical Science and Technolog. Guangxi UniversityNanning 530004GuangxiChina Heb.i Normal University Shijiazhuang 050024HebeiChina School of Physics and Microelectronics Zhengzhou UniversityZhengzhou 450001HenanChina School of Astronomy and Space Science Nanjing UniversityNanjing 210023JiangsuChina Key Lab.ratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023JiangsuChina Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdao 266237ShandongChina Key Lab.ratory for Research in g.laxies and Cosmolog. Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China Tsung.Dao Lee Institute&School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China School of Physical Science and Technolog.&School of Information Science and Technolog. Southwest Jiaotong UniversityChengdu 610031SichuanChina Colleg. of Physics Sichuan UniversityChengdu 610065SichuanChina Key Lab.ratory of Cosmic Rays(Tib.t University) Ministry of EducationLhasa 850000TibetChina School of Physic

Purpose Ob.ervation of hig. energ. and very hig. emission from g.mma Ray b.rsts(g.b.)is crucial to study the g.g.ntic explosion and the underline *** a larg. field-of-view and almost full duty cycle,the Water Cherenkov Detector Array(WCDA),a sub.array of the Larg. Hig. Altitude Air Shower Ob.ervatory(LHAASO),is appropriate to monitor the very hig. energ. emission from unpredictab.e transients such as *** Nevertheless,the main issue for an extensive air shower array is the hig. energ. threshold which limits the horizon of the *** address this issue a new trig.er method is developed in this article to lower the energ. threshold of WCDA for g.b.*** The proposed method sig.ificantly improves the detection efficiency of WCDA for g.mma-rays around the g.b.direction at 10-300 *** sensitivity of the WCDA for g.b.detection with the new trig.er method is *** achieved sensitivity of the quarter WCDA array ab.ve 10 g.V is comparab.e with that of *** data analysis process and corresponding.fluence upper limit for g.b.190719C is presented as an example.

关键词： LHAASO WCDA g.b

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Productive Performance and Response of g.een Chilli （Capsicum annum L.） to Drip Irrig.tion Schedules under Water Limited Conditions

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Journal of Ag.icultural Science and Technolog. 2010年第2期4卷 48-55页

作者： b.K. Ramachandrappa H.V. Nanjappa T.M. Soumya b.N. Prab.akara Department of Ag.onomy Agriculture College University of Agricultural Sciences GKVK Bangalore Karnataka 560065 India

Drip irrig.tion is often preferred under water limited conditions over the other irrig.tion methods b.cause of its hig. water application efficiency on account of reduced surface evaporation and percolation losses. The major limitation of drip irrig.tion is its initial investment. Therefore, there is a need to reduce the cost of drip installation b. altering.the planting.g.ometry b.sides enhancing.the productivity and moisture use. Results of the two years field study conducted on sandy loam soils revealed that drip irrig.tion at 1.0 Epan with normal row system （60 cm×30 cm） reg.stered sig.ificantly hig.er yield of g.een chilli（ 14.08 t ha^-1） which was on par with 0.8 Epan two rows paired system （90-45-90 cm×30 cm：13.45 t ha^-1） and sig.ificantly lowest was noticed with 0.6 Epan four rows paired system（45-45-45-120 cm×30 cm ）（5.50 t ha^-1）. The quality parameters viz; TSS and Ascorb.c acid were sig.ificantly hig.er with drip irrig.tion at 1.0 Epan with normal row system and lowest was ob.erved with 0.6 Epan four rows paired system. Total water used was maximum in 1.0 Epan （691.7 mm） followed b. 0.8 Epan irrig.tion （590.2 mm） and the lowest was recorded in 0.6 Epan irrig.tion （488.8 mm）. There was a saving.of water b. 14.68 percent and 29.34 percent under 0.8 and 0.6 Epan drip irrig.tion schedules respectively over 1.0 Epan. Indications of less leaf water potential in 1.0 Epan drip irrig.tion （-0.58 to-0.67 MPa） followed b. 0.8 Epan （-0.61 to-0.68 MPa） and more neg.tive leaf water potential in 0.6 Epan （-0.71 to-0.88 MPa） in relation to water applied were ob.erved. Water use efficiency recorded was maximum in 0.6 Epan normal row systems （24.1 Kg.ha-mm^-1） and the least was recorded in 0.6 Epan four rows paired system （11.3 Kg.ha-mm^-1）. The sig.ificantly hig.er root g.owth characters such as root leng.h （42.6 cm）, numb.r of primary roots （28.7）, root dry weig.t （11.05 g.plant^-1） and maximum depth of penetration were recorded with 0.6 Epan four rows paired system a

关键词： Drip irrig.tion g.eenchilli planting.method water requirement leaf water potential root proliferation

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巯基捕收剂浮选细粒的某些特性

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矿冶 1998年第2期7卷 21-26页

作者： Petrov I A Davydov g.I Studencov V V Revazashili I b.(Kazmekhanob.,Repub.ic of Kazakhstan) 哈萨克斯坦国家工业生态科技生产联合体

阐明了浮选不同粒级硫化物巯基捕收剂作用的研究。结果表明，当浮选细粒硫化物时，由于黑药的结构特点（有两个非极性基），它比黄药优越。按矿粒在气泡上沿环固着的假说，探讨了使用黄药和黑药时存在不同的矿物－气泡集合体的作用机理... 详细信息

阐明了浮选不同粒级硫化物巯基捕收剂作用的研究。结果表明，当浮选细粒硫化物时，由于黑药的结构特点（有两个非极性基），它比黄药优越。按矿粒在气泡上沿环固着的假说，探讨了使用黄药和黑药时存在不同的矿物－气泡集合体的作用机理。研究结果可用于修正选厂的药剂制度。

关键词：捕收剂细粒浮选巯基捕收剂细矿粒

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计算训练法

计算训练法

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作者：詹姆斯·加德纳(Jr.b. g.rdne) 格里·珀迪(J.g. Purdy)

来源：南通市图书馆图书评论

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