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Comparison of free breathing and respiratory triggered diffusion-weighted imaging sequences for liver imaging

World Journal of Radiology 2019年第11期11卷 134-143页

作者： Janio Szklaruk Jong Bum Son Wei Wei Priya Bhosale sanaz javadi Jingfei Ma Department of Diagnostic Radiology The University of Texas MD Anderson Cancer CenterHoustonTX 77030United States Department of Imaging Physics The University of Texas MD Anderson Cancer CenterHoustonTX 77030United States Department of Biostatistics The University of Texas MD Anderson Cancer CenterHoustonTX 77030United States

BACKGROUND Diffusion-weighted imaging(DWI)has become a useful tool in the detection,characterization,and evaluation of response to treatment of many cancers,including malignant liver *** offers higher image contrast between lesions and normal liver tissue than other *** images acquired at two or more b-values can be used to derive an apparent diffusion coefficient(ADC).DWI in the body has several technical *** include ghosting artifacts,mis-registration and susceptibility *** DWI sequences have been developed to overcome some of these *** goal is to evaluate 3 new DWI sequences for liver *** To qualitatively and quantitatively compare 3 DWI sequences for liver imaging:free-breathing(FB),simultaneous multislice(SMS),and prospective acquisition correction(PACE).METHODS Magnetic resonance imaging(MRI)was performed in 20 patients in this prospective *** MR study included 3 separate DWI sequences:FB-DWI,SMS-DWI,and *** image quality,mean ADC,standard deviations(SD)of ADC,and ADC histogram were *** signed-rank tests were used to compare qualitative image quality.A linear mixed model was used to compare the mean ADC and the SDs of the ADC *** tests were 2-sided and P values of<0.05 were considered statistically *** There were 56 lesions(50 malignant)evaluated in this *** mean qualitative image quality score of PACE-DWI was *** was significantly better than that of SMS-DWI(4.22)and FB-DWI(3.15)(P<0.05).Quantitatively,the mean ADC values from the 3 different sequences did not significantly differ for each liver ***-DWI had a markedly higher variation in the SD of the ADC values than did SMS-DWI and *** found statistically significant differences in the SDs of the ADC values for FB-DWI vs PACE-DWI(P<0.0001)and for FB-DWI vs SMS-DWI(P=0.03).The SD of the ADC values was not statistically significant for PACE-DWI and SMS-DWI(P=0.18).The quality

关键词： Diffusion Magnetic resonance imaging Liver Apparent diffusion coefficient Prospective acquisition correction Multi-slice

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