检索结果-南通市图书馆

single-atom Pt on carbon nanotubes for selective electrocatalysis

第十四届全国中药和天然药物学术研讨会

作者： Guohui Li Zaijun Zhang Quan Quan Yun Zhao samuel s.w.szeto Herman Lam simon M.Y.Lee Ivan K.Chu The University of Hong Kong Jinan University University of Macau

＜正＞Although ethanolic extract of Alpinia oxyphylla（AOE）has displayed promising protective effects against 6-hydroxydopamine（6-OHDA）-induced injury in PC12 cells and zebrafish dopaminergic neurons,its bioactive components have remained *** this present study,we elucidated the synergistic neuroprotective effects of two polyphenols present in

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Carbon Energy 2024年第1期6卷 63-71页

作者： samuel s.Hardisty Xiaoqian Lin Anthony R.J.Kucernak David Zitoun Department of Chemistry Bar Ilan Institute of Nanotechnology and Advanced Materials(BINA)Bar Ilan UniversityRamat GanIsrael Department of Chemistry Molecular Science Research HubImperial College LondonLondonUK

Utilizing supported single atoms as catalysts presents an opportunity to reduce the usage of critical raw materials such as platinum,which are essential for electrochemical reactions such as hydrogen oxidation reaction(HOR).Herein,we describe the synthesis of a Pt single electrocatalyst inside single-walled carbon nanotubes(swCNTs)via a redox *** via electron microscopy,X-ray photoelectron microscopy,and X-ray absorption spectroscopy show the single-atom nature of the *** electrochemical behavior of the sample to hydrogen and oxygen was investigated using the advanced floating electrode technique,which minimizes mass transport limitations and gives a thorough insight into the activity of the *** single-atom samples showed higher HOR activity than state-of-the-art 30%Pt/C while almost no oxygen reduction reaction activity in the proton exchange membrane fuel cell operating *** selective activity toward HOR arose as the main fingerprint of the catalyst confinement in the swCNTs.

关键词： confinement electrocatalysis hydrogen platinum single atom catalysts

A tribo-chemical view on astringency of plant-based food substances

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Friction 2024年第7期12卷 1392-1407页

作者： samuel s.GAMANIEL Paloma s.DUEÑAs ROBLEs Hans TROMP Els H.A.de HOOG sissi de BEER Emile van der HEIDE Laboratory for surface Technology and Tribology Faculty of Engineering TechnologyUniversity of TwenteEnschede 7522 LWthe Netherlands NIZO Food Research B.V. Ede6710 BAthe Netherlands Department of Molecules and Materials MEsA+Institute for Nanotechnology University of TwenteEnschede 7500 AEthe Netherlands

Consumption of plant-based food products having high composition of polyphenols leads to the sensation of *** sliding oral surfaces,friction is an essential property during the oral perception of roughness and dryness which are attributes associated with *** factors including the chemical composition of interacting layers,structure and operation of interfaces have an effect on the astringency development *** manner of interactions occurring at oral interfaces suggest there is a system dependence of astringency and highlights the importance of adopting a tribosystems *** measurement techniques have shown an existing relationship between salivary protein-polyphenol interaction and an astringent ***,the tribo-chemistry involved in this multifaceted sensation remains largely unexplored in a comprehensive *** this review the underlying tribo-chemical processes useful in understanding the mechanism of astringency are highlighted and discussed considering current techniques employed to investigate astringency *** of lubrication on oral surfaces owing to the tribo-chemical interactions involving saliva and astringent plant proteins requires subsequent deformations of oral tissues which are significant enough to induce strains at mechanoreceptor locations,leading to the sensation of *** is proposed that micro-scale contact modelling on the interaction of food particles/aggregates,boundary layers and oral surfaces shows potential in addressing the knowledge gap between tribo-chemical measurement techniques and panel tests,making it possible to attain a predictor for astringency.

关键词： oral lubrication astringency tribo-chemistry tribology

Fish-on-Chips:unveiling neural processing of chemicals in small animals through precise fluidic control

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第11期19卷 2351-2353页

作者： samuel K.H.sy Ho Ko Division of Neurology Department of Medicine and TherapeuticsFaculty of MedicineThe Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina Li Ka shing Institute of Health sciences Faculty of MedicineThe Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina Department of Electrical and Electronic Engineering Faculty of EngineeringThe University of Hong KongPok Fu LamHong Kong IslandHong Kong Special Administrative RegionChina Advanced Biomedical Instrumentation Center Hong Kong Science ParkPak Shek KokNew TerritoriesHong Kong Special Administrative RegionChina Margaret K.L.Cheung Research Center for Management of Parkinsonism Faculty of MedicineThe Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina Lau Tat-chuen Research Center of Brain Degenerative Diseases in Chinese Faculty of MedicineThe Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina Gerald Choa Neuroscience Institute The Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina

Precise chemical cue presentation alongside advanced brainwide imaging techniques is important to the study of chemosensory processing in ***,the dynamic nature of chemical-carrying media,such as water or air,poses a significant challenge for delivering highly-controlled chemical flow to an animal ***,contact-based cue manipulation and delivery easily shift the position of the animal subject,which is often undesirable for high-quality brain ***,more advanced interfacing tools that align with the diverse range of body part sizes of an animal,ranging from micrometer-scale neurons to meter-long limbs,are much *** is particularly crucial when dealing with dimensions that are beyond the reach of conventional experimental tools.

关键词： dealing precise sizes

soluble p75 neurotrophic receptor as a reliable biomarker in neurodegenerative diseases: what is the evidence?

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第3期19卷 536-541页

作者： Georges Jourdi samuel Fleury Imane Boukhatem Marie Lordkipanidzé Research Center Montreal Heart InstituteMontrealQCCanada Faculty of Pharmacy Universitéde MontréalMontrealQCCanada UniversitéParis Cité INSERMInnovative Therapies in HaemostasisParisFrance service d’Hématologie Biologique AP-HPHôpital LariboisièreParisFrance

Neurodegenerative diseases are often misdiagnosed,especially when the diagnosis is based solely on clinical *** p75 neurotrophic receptor(p75^(NTR))has been studied as an index of sensory and motor nerve development and *** cleavable extracellular domain(ECD)is readily detectable in various biological fluids including plasma,serum and *** is evidence for increased p75NTR ECD levels in neurodegenerative diseases such as Alzheimer’s disease,amyotrophic lateral sclerosis,age-related dementia,schizophrenia,and diabetic *** p75^(NTR) ECD could be used as a biomarker for diagnosis and/or prognosis in these disorders,and whether it could potentially lead to the development of targeted therapies,remains an open *** this review,we present and discuss published studies that have evaluated the relevance of this emerging biomarker in the context of various neurodegenerative *** also highlight areas that require further investigation to better understand the role of p75^(NTR) ECD in the clinical diagnosis and management of neurodegenerative disorders.

关键词： Alzheimer’s disease amyotrophic lateral sclerosis biomarker dementia diabetic neuropathy nerve growth factor receptor(NGFR) neurodegeneration p75^(NTR) schizophrenia

A direct polymeric carbon nitride/tungsten oxide Z-scheme heterostructure for efficient photocatalytic hydrogen generation via reforming of plastics into value-added chemicals

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2024年第8期43卷 3771-3783页

作者： Rui-Zhe wang Zhi Lin Yi-Qing wang Kai-Ni Zhang Ge-Hong Zhang Jie Zhang samuel s.Mao shao-Hua shen International Research Center for Renewable Energy State Key Laboratory of Multiphase Flow in Power EngineeringXi'an Jiaotong UniversityXi'an 710049China school of Civil and Architecture Engineering Xi'an Technological UniversityXi'an 710021China Department of Mechanical Engineering University of California at BerkeleyBerkeleyCA94720USA

To promote charge transfer and separation for efficient photocatalysis,a direct Z-scheme heterostructure was constructed by coupling polymeric carbon nitride(PCN) and wO_(3).Interestingly,the obtained PCN/wO_(3)Z-scheme heterostructure could photocataly tic ally produce hydrogen and value-added chemicals(e.g.,formate and acetate) by reforming of plastic polylactic acid(PLA) in alkaline aqueous *** optimizing wO_(3) contents and reaction conditions,the obtained PCN/wO_(3)heterostructure exhibits much increased photocatalytic activity for PLA photoreforming under visible light,with hydrogen evolution rate reaching 402.90 μmol·g~(-1)·h~(-1),which is 3.5 times that of *** is revealed that the Z-scheme charge transfer between PCN and wO_(3) mainly contributes to the promoted charge separation and thus the improved photocatalytic ***,with h+and·OH experimentally evidenced as the predominant active species,a possible reaction pathway for the reforming of PLA into value-added chemicals(e.g.,formate and acetate)over PCN/wO_(3) Z-scheme heterostructure is cleared by monitoring the reaction intermediates and *** work paves a carbon neutrality and scalable route toward the synergistical production of hydrogen and value-added chemicals by utilizing and recycling plastic waste.

关键词： Carbon nitride Z-scheme heterojunction Plastic waste conversion Photocatalytic H_(2)production Value-added chemicals

Green hydrogen production from photovoltaic power station as a road map to climate change mitigation

在线全文

学校读者我要写书评

暂无评论

CLEAN ENERGY 2024年第2期8卷 156-167页

作者： Kamil, Kehinde Ridwan samuel, Bassey Okon Khan, Umar Edge Hill Univ Dept Comp Sci & Engn Ormskirk England ENEL Green Power Rome Italy steelagon Engn Ltd Mat Res Lab Sabon Gari Kaduna State Nigeria

The increasing recognition of hydrogen as a critical element in the global net-zero transition and its clear role in decarbonizing challenging sectors coincide with the growing urgency to address climate change. Africa's favourable renewable-energy capacity, ranging from 28% to 36% for solar, has been reported by the global solar irradiance index. However, the majority of hydrogen production today relies on fossil fuels (96%), with only a small fraction (4%) being produced through water electrolysis. Even though there have been many studies on climate change mitigation with a focus on Africa, a green hydrogen production from a photovoltaic power station approach has not been reported. Also, literature with a focus on Nigeria is lacking. This study focuses on the African green hydrogen production industry, utilizing Nigeria as a case study to explore the feasibility of generating clean hydrogen vectors from a percentage of photovoltaic power output in various regions of the country through stand-alone solar grid electrification projects. Analyses of the usage and effectiveness of the produced hydrogen fuel in each region are carried out, with the highest region having an annual output of 12 247 278 kg of green hydrogen and 8 573 094 kg of ammonia and the lowest region having an output of 511 245 kg of green hydrogen and 357 871 kg of ammonia, and the expected production from the proposed usage of 50% of the power generation output of the installed 1.6-Mwp and 80-kwp solar power minigrids in the regions is calculated. The analyses were repeated for the other considered regions in the country. The results showcased the enormous advantages of the electrolytic production of hydrogen and how the greener economy project can play a major role in mitigating climate change effects and overreliance on fossil fuels as the driver of the economy in many African countries. Nigeria is used as a case study for the African green hydrogen production industry to explore the feasibility

关键词： renewable energy photovoltaic climate change green hydrogen vector fossil fossil fuels decarbonization electrolysis AMMONIA wATER CELL

Chatbots:a critical look into the future of the academia

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Agricultural and Biological Engineering 2024年第2期17卷 287-288页

作者： samuel Ariyo Okaiyeto Arun s.Mujumdar Parag Prakash sutar wei Liu Junwen Bai Hongwei Xiao College of Engineering China Agricultural UniversityBeijing 100083China Department of Bioresource Engineering McGill UniversitySte.Anne de BellevueQuebecCanada Department of Food Process Engineering National Institute of Technology RourkelaRourkela 769008India school of Artificial Intelligence Beijing University of Posts and TelecommunicationsBeijing 100876China school of Food and Biological Engineering Jiangsu UniversityZhenjiang 212013China

Like every other societal domain,science faces yet another reckoning caused by a bot called ChatGPT(Chat Generative Pre-Trained Transformer).ChatGPT was introduced in November 2022 to produce messages that seem like they were written by humans and are *** the release of the latest version of ChatGPT called GPT-4,and other similar models such as Google Bard,Chatsonic,Collosal Chat,these chatbots combine several(about 175 billion)neural networks pre-trained on large Language Models(LLMs),allowing them to respond to user promptings just like ***-4 for example can admit its mistakes and confront false assumptions thanks to the dialogue style,which also enables it to write essays and to keep track of the context of a discussion while it is ***,users may be deceived by the human-like text structure of the AI models to believe that it came from a human origin[1].These chatbot models could be better,even though they generate text with a high level of ***,they produce inappropriate or wrong responses,resulting in faulty inferences or ethical *** article will discuss some fundamental strengths and weaknesses of this Artificial intelligence(AI)system concerning scientific research.

关键词： ChatGPT AI generative models academia ethical and moral restraints

Exploring the effects of taurolidine on tumor weight and microvessel density in a murine model of osteosarcoma

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Oncology Research 2024年第7期32卷 1163-1172页

作者： LIsANNE K.A.NEIJENHUIs LEUTA L.NAUMANN sONIA A.M.FERKEL samuel J.s.RUBIN sTEPHAN ROGALLA Division of Gastroenterology and Hepatology Department of MedicineSchool of MedicineStanford UniversityStanford94305USA Department of surgery Leiden University Medical CenterLeiden2333 ZAThe Netherlands Centre for Human Drug Research Leiden2333 CLThe Netherlands Department of General VisceralVascular and Thoracic SurgeryCharite University Medicine BerlinBerlin10117Germany

Background:Osteosarcoma is the most common malignant primary bone *** prognosis for patients with disseminated disease remains very poor despite recent advancements in ***,current treatment regimens bear a signiﬁcant risk of serious side ***,there is an unmet clinical need for effective therapies with improved safety proﬁ*** is an antibacterial agent that has been shown to induce cell death in different types of cancer cell ***:In this study,we examined both the antineoplastic and antiangiogenic effects of taurolidine in animal models of osteosarcoma.K7M2 murine osteosarcoma cells were injected,both intramuscular and intraperitoneal,into 60 BALB/c mice on day *** were then randomized to receive treatment with taurolidine 2%(800 mg/kg),taurolidine 1%(400 mg/kg),or NaCl 0.9%control for seven days by intravenous or intraperitoneal ***:After 35 days,mice were euthanized,and the tumors were harvested for *** mice were excluded from the analysis due to *** weight was signiﬁcantly lower in the 2%taurolidine intraperitoneal treatment group from day 9 to 21,consistent with elevated mortality in this *** tumor weight was signiﬁcantly lower in the 1%(p=0.003)and 2%(p=0.006)intraperitoneal taurolidine treatment groups compared to the *** antineoplastic effects were observed on intramuscular tumors or for intravenous administration of *** were no signiﬁcant differences in microvessel density or mitotic rate between treatment *** body weight and elevated mortality in the 2%taurolidine intraperitoneal group suggest that the lower 1%dose is ***:In conclusion,there is no evidence of antiangiogenic activity,and the antitumor effects of taurolidine on osteosarcoma observed in this study are ***,its toxic proﬁle grants further *** these observations,further research is necessary to

关键词： Osteosarcoma Taurolidine Cancer treatment Chemotherapy Murine models

small molecules to target tau amyloid aggregation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第3期19卷 509-511页

作者： Zoe Manglano-Artuñedo samuel Peña-Díaz salvador Ventura Institut de Biotecnologia i Biomedicina Universitat Autònoma de BarcelonaBellaterraSpain

Protein aggregation has been linked with many neurodegenerative diseases,such as Alzheimer’s disease(AD)or Parkinson’s *** belongs to a group of heterogeneous and incurable neurodegenerative disorders collectively known as *** comprise frontotemporal dementia,Pick’s disease,or corticobasal degeneration,among *** symptomatology varies with the specific tau protein variant involved and the affected brain region or cell ***,they share a common neuropathological hallmark-the formation of proteinaceous deposits named neurofibrillary *** tangles,primarily composed of aggregated tau(Zhang et al.,2022),disrupt normal neuronal functions,leading to cell death and cognitive decline.

关键词： tau degeneration aggregation