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4D imaging of void nucleation,growth,and coalescence from large and small inclusions in steel under tensile deformation

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Journal of Materials Science & Technology 2022年第28期123卷 168-176页

作者： Yi Guo Timothy L.Burnett samuel A.McDonald Michael Daly Andrew h.Sherry Philip J.Withers Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China henry Royce Institute Department of MaterialsUniversity of ManchesterM139PLUK European Synchrotron Radiation Facility(ESRF) 6 rue J Horowitz38000 GrenobleFrance National Nuclear Laboratory Chadwick HouseBirchwood ParkWarringtonWA36AEUK

Samples of SA508 grade 3 nuclear pressure vessel ferritic steel were subjected to tensile straining whilst being simultaneously imaged in 3D in real time using high resolution,high frame rate time-lapse synchrotron computed tomography(CT).This enabled direct observation of void development from nucleation,through growth to coalescence and final failure validating many inferences made post-mortem or by theoretical models,as well as raising new *** sparse,large inclusions were found to nucleate voids at essentially zero plastic strain(consistent with zero interfacial strength);these became increasingly elongated with *** contrast,a high density of small spherical voids were found to nucleate from the sub-micron cementite particles at larger strains(>200%)only in the centre of the necked(high triaxiality)*** interfacial strength approaching 2100 MPa was inferred and soon after their nucleation,these small voids coalesce to form internal microcracks that lead to the final failure of the *** surprisingly,under these conditions of generally low triaxial constraint the large voids are simply cut across and appear to play no significant role in determining the final *** implications of these results are discussed in terms of ductile fracture behaviour and the Gurson model for ductile fracture.

关键词： Void growth Ductile fracture Synchrotron X-ray tomography 4D imaging Bainitic steel

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Molecular bridge-mediated ultralow-power gas sensing

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Microsystems & Nanoengineering 2021年第2期7卷 143-153页

作者： Aishwaryadev Banerjee Shakir-Ul haque Khan samuel Broadbent Ashrafuzzaman Bulbul Kyeong heon Kim Seungbeom Noh R.Looper C.h.Mastrangelo h.Kim Department of Electrical and Computer Engineering University of UtahSalt Lake CityUT84112USA Department of Chemistry University of UtahSalt Lake CityUT84112USA Gyeongsang National University JinjuSouth Korea

We report the electrical detection of captured gases through measurement of the quantum tunneling characteristics of gas-mediated molecular junctions formed across *** gas-sensing nanogap device consists of a pair of vertically stacked gold electrodes separated by an insulating 6 nm spacer(~1.5 nm of sputteredα-Si and~4.5 nm ALD SiO2),which is notched~10 nm into the stack between the gold *** exposed gold surface is functionalized with a self-assembled monolayer(SAM)of conjugated thiol linker *** the device is exposed to a target gas(1,5-diaminopentane),the SAM layer electrostatically captures the target gas molecules,forming a molecular bridge across the *** gas capture lowers the barrier potential for electron tunneling across the notched edge region,from~5 eV to~0.9 eV and establishes additional conducting paths for charge transport between the gold electrodes,leading to a substantial decrease in junction *** demonstrated an output resistance change of>108 times upon exposure to 80 ppm diamine target gas as well as ultralow standby power consumption ofhrough molecular bridges for ultralow-power gas sensing.

关键词： tunneling bridge bridges

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Expression of micro RNAs in fibroblast of pterygium

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International Journal of Ophthalmology(English edition) 2016年第7期9卷 967-972页

作者： Joon h.Lee Sun-Ah Jung Young-A Kwon Jea-Lim Chung Ungsoo samuel Kim Myung-Gok Eye Research Institute Konyang University College of Medicine Seoul 07301 Korea Department of Ophthalmology Kim's Eye Hospital Seoul 07301 Korea Department of Ophthalmology Konyang University College of Medicine Daejeon 35356 Korea

AIM：To screen microRNAs（miRNAs） and set up target miRNAs in ***：Primary fibroblasts were isolated from pterygium and Tenon＇s capsule and *** analysis and Western blotting were performed to confirm the culture of *** all,1733 miRNAs were screened in the first step by using GeneChip miRNA3.0 *** miRNAs involved in the pathogenesis of pterygium were subsequently determined using the following criteria：1） high reproducibility in a repetitive test;2） base log value of 〉7.0 for both control and pterygial fibroblasts;and 3） log ratio of 〉1.0 between pterygial fibroblasts and control ***：Primary screening showed that 887/1733 miRNAs were up-regulated and 846/1733 miRNAs were down-regulated in pterygial fibroblasts compared with those in control *** the 1733 miRNAs screened,4 miRNAs,namely,miRNA-143a-3p,miRNA-181a-2-3p,miRNA-377-5p and miRNA-411a-5p,met the above-mentioned *** screening showed that these 4 miRNAs were up-regulated in pterygial fibroblasts compared with control fibroblasts and that miRNA-143a-3p had the highest mean ratio compared with the miRNAs in control ***：miRNA-143a-3p,miRNA-181a-2-3p,miRNA-377-5p and miRNA-411a-5p are up-regulated in pterygial fibroblasts compared with control fibroblasts,suggesting their involvement in the pathogenesis of pterygium.

关键词： microRNA pterygium fibroblast

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G-Algebra Structure on the higher Order hochschild Cohomology h*_(S)^(2)(A,A)

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Algebra Colloquium 2022年第1期29卷 113-124页

作者： samuel Carolus Mihai D.Staic Department of Mathematics and Statistics Ohio Northern University AdaOH 45810USA Department of Mathematics and Statistics Bowling Green State University Bowling GreenOH 43403USA Institute of Mathematics of the Romanian Academy PO.BOX 1-764 RO-70700 BucharestRomania

We present a deformation theory associated to the higher hochschild coho-mology h*_(S)^(2)(A,A).We also study a G-algebra structure associated to this deformation theory.

关键词： higher hochschild cohomology operad G-algebra

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Deobfuscation,unpacking,and decoding of obfuscated malicious JavaScript for machine learning models detection performance improvement

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CAAI Transactions on Intelligence Technology 2020年第3期5卷 184-192页

作者： samuel Ndichu Sangwook Kim Seiichi Ozawa Graduate School of Engineering Kobe UniversityKobe CityJapan Center for Mathematical and Data Sciences Kobe UniversityKobe CityJapan

Obfuscation is rampant in both benign and malicious JavaScript(JS)*** generates an obscure and undetectable code that hinders comprehension and ***,accurate detection of JS codes that masquerade as innocuous scripts is *** existing deobfuscation methods assume that a specific tool can recover an original JS code *** a multi-layer obfuscation,general tools realize a formatted JS code,but some sections remain *** the detection of such codes,this study performs Deobfuscation,Unpacking,and Decoding(DUD-preprocessing)by function redefinition using a Virtual Machine(VM),a JS code editor,and a python int_to_str()function to facilitate feature learning by the FastText *** learned feature vectors are passed to a classifier model that judges the maliciousness of a JS *** performance evaluation,the authors use the hynek Petrak’s dataset for obfuscated malicious JS codes and the SRILAB dataset and the Majestic Million service top 10,000 websites for obfuscated benign JS *** then compare the performance to other models on the detection of DUD-preprocessed obfuscated malicious JS *** experimental results show that the proposed approach enhances feature learning and provides improved accuracy in the detection of obfuscated malicious JS codes.

关键词： JavaScript editor python

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一种新的快速模糊规则提取方法

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控制与决策 2008年第9期23卷 1015-1020页

作者：陈铁明龚荣盛 samuel h huang 浙江工业大学软件学院杭州310014 北京航空航天大学软件开发环境国家重点实验室北京100086 辛辛那提大学工程学院美国辛辛那提45221

提出一种高效的规则提取算法,采用熵测量改进Chi-merge特征区间离散化方法,模糊划分输入空间.先为每个数据生成单条规则,再聚集相同前项的单条规则产生带概率属性的分类规则.提取的规则无需任何调整,应用模糊推理便可获得较理想的分类效... 详细信息

提出一种高效的规则提取算法,采用熵测量改进Chi-merge特征区间离散化方法,模糊划分输入空间.先为每个数据生成单条规则,再聚集相同前项的单条规则产生带概率属性的分类规则.提取的规则无需任何调整,应用模糊推理便可获得较理想的分类效果,同时支持增量式规则更新.最后给出了新方法的性能测试结果.

关键词：模糊规则规则提取 Chi-merge方法离散化模糊推理

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神经密码协议模型研究

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计算机研究与发展 2009年第8期46卷 1316-1324页

作者：陈铁明 samuel h.huang 刘多蔡家楣北京航空航天大学软件开发环境国家重点实验室北京100191 浙江工业大学计算机科学与技术学院杭州310014 辛辛那提大学智能系统实验室美国俄亥俄州辛辛那提45221

利用离散的神经网络模型构建密码协议是信息安全领域一项新的研究内容.首先介绍了一个基于神经网络的树型奇偶机模型,在综述基于树型奇偶机的神经密码协议研究基础上,分析了神经密码协议的权值同步方案存在模型稳定性和同步判定安全性问... 详细信息

利用离散的神经网络模型构建密码协议是信息安全领域一项新的研究内容.首先介绍了一个基于神经网络的树型奇偶机模型,在综述基于树型奇偶机的神经密码协议研究基础上,分析了神经密码协议的权值同步方案存在模型稳定性和同步判定安全性问题,分别提出在激活函数中增加阈值和利用hash函数判定同步权值的改进方法,并利用方差分析和统计实验给出仿真结果,证实了神经密码协议的可行性,最后讨论了协议模型的安全攻击问题.

关键词：神经网络树型奇偶机权值同步密码协议密钥协商

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A tribo-chemical view on astringency of plant-based food substances

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Friction 2024年第7期12卷 1392-1407页

作者： samuel S.GAMANIEL Paloma S.DUEÑAS ROBLES hans TROMP Els h.A.de hOOG Sissi de BEER Emile van der hEIDE Laboratory for Surface Technology and Tribology Faculty of Engineering TechnologyUniversity of TwenteEnschede 7522 LWthe Netherlands NIZO Food Research B.V. Ede6710 BAthe Netherlands Department of Molecules and Materials MESA+Institute for Nanotechnology University of TwenteEnschede 7500 AEthe Netherlands

Consumption of plant-based food products having high composition of polyphenols leads to the sensation of *** sliding oral surfaces,friction is an essential property during the oral perception of roughness and dryness which are attributes associated with *** factors including the chemical composition of interacting layers,structure and operation of interfaces have an effect on the astringency development *** manner of interactions occurring at oral interfaces suggest there is a system dependence of astringency and highlights the importance of adopting a tribosystems *** measurement techniques have shown an existing relationship between salivary protein-polyphenol interaction and an astringent ***,the tribo-chemistry involved in this multifaceted sensation remains largely unexplored in a comprehensive *** this review the underlying tribo-chemical processes useful in understanding the mechanism of astringency are highlighted and discussed considering current techniques employed to investigate astringency *** of lubrication on oral surfaces owing to the tribo-chemical interactions involving saliva and astringent plant proteins requires subsequent deformations of oral tissues which are significant enough to induce strains at mechanoreceptor locations,leading to the sensation of *** is proposed that micro-scale contact modelling on the interaction of food particles/aggregates,boundary layers and oral surfaces shows potential in addressing the knowledge gap between tribo-chemical measurement techniques and panel tests,making it possible to attain a predictor for astringency.

关键词： oral lubrication astringency tribo-chemistry tribology

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Soluble p75 neurotrophic receptor as a reliable biomarker in neurodegenerative diseases: what is the evidence?

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Neural Regeneration Research 2024年第3期19卷 536-541页

作者： Georges Jourdi samuel Fleury Imane Boukhatem Marie Lordkipanidzé Research Center Montreal Heart InstituteMontrealQCCanada Faculty of Pharmacy Universitéde MontréalMontrealQCCanada UniversitéParis Cité INSERMInnovative Therapies in HaemostasisParisFrance Service d’hématologie Biologique AP-HPHôpital LariboisièreParisFrance

Neurodegenerative diseases are often misdiagnosed,especially when the diagnosis is based solely on clinical *** p75 neurotrophic receptor(p75^(NTR))has been studied as an index of sensory and motor nerve development and *** cleavable extracellular domain(ECD)is readily detectable in various biological fluids including plasma,serum and *** is evidence for increased p75NTR ECD levels in neurodegenerative diseases such as Alzheimer’s disease,amyotrophic lateral sclerosis,age-related dementia,schizophrenia,and diabetic *** p75^(NTR) ECD could be used as a biomarker for diagnosis and/or prognosis in these disorders,and whether it could potentially lead to the development of targeted therapies,remains an open *** this review,we present and discuss published studies that have evaluated the relevance of this emerging biomarker in the context of various neurodegenerative *** also highlight areas that require further investigation to better understand the role of p75^(NTR) ECD in the clinical diagnosis and management of neurodegenerative disorders.

关键词： Alzheimer’s disease amyotrophic lateral sclerosis biomarker dementia diabetic neuropathy nerve growth factor receptor(NGFR) neurodegeneration p75^(NTR) schizophrenia

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一种新的快速特征选择和数据分类方法

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计算机研究与发展 2012年第4期49卷 735-745页

作者：陈铁明马继霞 samuel h.huang 蔡家楣浙江工业大学计算机科学与技术学院杭州310023 软件开发环境国家重点实验室(北京航空航天大学) 北京100191 辛辛那提大学智能系统实验室美国辛辛那提45221

针对数据分类问题提出一种新型高效的特征选择和规则提取方法.首先通过减少初始区间数量改进Chi-Merge离散化方法,再采用改进的Chi-Merge离散化连续型特征变量;特征离散化后,统计样本数据在每个特征子集划分下的频数表,并根据频数表计... 详细信息

针对数据分类问题提出一种新型高效的特征选择和规则提取方法.首先通过减少初始区间数量改进Chi-Merge离散化方法,再采用改进的Chi-Merge离散化连续型特征变量;特征离散化后,统计样本数据在每个特征子集划分下的频数表,并根据频数表计算数据不一致率,再利用顺序前向最优搜索的方法,快速确定特征数量由小到大的每一个最优特征子集;根据特征子集对应的数据不一致率差异最小化原则,完成特征个数最小化的最优特征子集筛选;根据最优特征子集的数据频数表,可直接提取数据分类规则.实验表明,快速提取的规则可获得较好的分类效果.基于该特征选择方法,提出一种面向分布式同构数据的快速分类模型,不但具有良好的分类效果,还支持对样本数据内容的隐私保护.

关键词：离散化频数表特征选择规则提取数据分类隐私保护

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