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Asian Pacific Journal of Tropical Biomedicine 2016年第12期6卷 1056-1064页

作者： samir abd el-monem bashandy Enayat abdel Aziz Omara Hossam Ebaid Mohamed Mahmoud Amin Mahmoud Sanad Soliman Department of Pharmacology Medical DivisionNational Research Centre Department of Pathology National Research Centre Department of Zoology College of ScienceKing Saud University Department of Zoology Faculty of ScienceEl-Minia University Department of Therapeutic Chemistry National Research Centre

Objective:To investigate the role of zinc in reducing the deleterious effects of cadmium on male ***:Rats were injected subcutaneously with CdCl_2 and ZnCl_2 at dose level of2.2 mg/kg(1/40 of LD50 of cadmium per day).Results:The rats treated with cadmium exhibited a significant increase in levels of testicular malondialdehyde,tumor necrosis factor-alpha,nitrogen oxide and inducible nitrogen oxide synthase immunostaining reaction,as well as an elevation of blood hydroperoxide and follicle stimulating *** addition,a significant decrease in testicular ascorbic acid,zinc,reduced glutathione,catalase,superoxide dismutase,sex organ weight,plasma testosterone and luteinizing hormone were observed in the cadmium *** motility and count were decreased with cadmium treatment,while sperm abnormalities elevated *** treatment was found to mitigate the toxic effects of cadmium on oxidative stress,spermatogenesis,sex hormones,and inflammatory *** injected with cadmium showed intense histopathological *** manifested protective role and markedly reduced tissues damage induced by ***:The protective effect of zinc can be attributed to its antioxidant and antiinflammatory properties.

关键词： Zinc Cadmium Oxidative stress Immunohistochemistry Sperms Inflammatory markers

Transpressive Structures in the Ghadir Shear Belt, Eastern Desert, Egypt: Evidence for Partitioning of Oblique Convergence in the Arabian-Nubian Shield during Gondwana Agglutination

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Acta Geologica Sinica(English Edition) 2019年第6期93卷 1614-1646页

作者： Mohamed abd el-WAHED samir KAMH Mahmoud ASHMAWY Aly SHEBL Geology Department Faculty of Science Tanta University

Transpressional deformation has played an important role in the late Neoproterozoic evolution of the ArabianNubian Shield including the Central Eastern Desert of *** Ghadir Shear Belt is a 35 km-long,NW-oriented brittleductile shear zone that underwent overall sinistral transpression during the Late *** this shear belt,strain is highly partitioned into shortening,oblique,extensional and strike-slip structures at multiple ***,strain partitioning is heterogeneous along-strike giving rise to three distinct structural *** the East Ghadir and Ambaut shear belts,the strain is pure-shear dominated whereas the narrow sectors parallel to the shear walls in the West Ghadir Shear Zone are simple-shear *** domains are comparable to splay-dominated and thrust-dominated strike-slip shear *** kinematic transition along the Ghadir shear belt is consistent with separate strike-slip and thrustsense shear *** earlier fabric(S1),is locally recognized in low strain areas and SW-ward thrusts.S2 is associated with a shallowly plunging stretching lineation(L2),and defines^NW-SE major upright macroscopic folds in the East Ghadir shear belt.F2 folds are superimposed by^NNW–SSE tight-minor and major F3 folds that are kinematically compatible with sinistral transpressional deformation along the West Ghadir Shear Zone and may represent strain partitioning during deformation.F2 and F3 folds are superimposed by ENE–WSW gentle F4 folds in the Ambaut shear *** sub-parallelism of F3 and F4 fold axes with the shear zones may have resulted from strain partitioning associated with simple shear deformation along narrow mylonite zones and pure shear-dominant deformation in fold *** ENEstriking shear zones were subsequently active at ca.595 Ma,coeval with sinistral shearing along NW-to NNW-striking shear *** occurrence of upright folds and folds with vertical axes suggests that transpression plays a significant role in

关键词： Arabian-Nubian Shield Ghadir shear belt transpression splay-dominated and thrust-dominated strike-slip shear zones Egypt

Lanthanide amino acid Schiff base complexes:synthesis,spectroscopic characterization,physical properties and in vitro antimicrobial studies

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Journal of Rare Earths 2013年第7期31卷 715-721页

作者： samir Alghool M.Sh.Zoromba Hanan F.abd el-Halim Department of Chemistry Faculty of SciencePort Said UniversityPort Said 42521Egypt Department of Chemistry Faculty of PharmacyMisr International UniversityIsmailia RoadKm 28 CairoEgypt

Complexes of La （III）, Nd（III）, Gd（III）, Sm（III）, and Ce（IV） were synthesized with Schiff base [（3,5-di-tert-butyl-2-hy- droxybenzyl） amino] acetic acid （H3L）. The ligand and its complexes were synthesized and characterized based on the following analysis： elemental analyses, FAB-mass, molar conductance measurements, magnetic measurement, UV-visible, IR, and NMR spectral studies. The spectral data revealed that the ligand acted as a neutral tridentate coordinating to metal ion through ONO donor sequence. Thermal degradation studies of the ligand and its complexes showed that the previous lanthanide complexes were more thermally stable than the ligand itself. The Schiff base and its complexes were screened for their antibacterial （Escherichia coli, Staphylococcus aureus） and antifungal （Aspergillus flavus and Candida Albicans）.

关键词： lanthanide Schiffbase complexes physical properties biological activity rare earths

Prediction Flashover Voltage on Polluted Porcelain Insulator Using ANN

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Computers, Materials & Continua 2021年第9期68卷 3755-3771页

作者： Ali Salem Rahisham abd-Rahman Waheed Ghanem samir Al-Gailani Salem Al-Ameri Faculty of electrical and electronic Engineering University Tun Hussein Onn MalaysiaJohor86400Malaysia Faculty of Ocean Engineering Technology and Informatics Universiti Malaysia TerengganuKuala Terengganu21030Malaysia School of electrical and electronic Engineering Universiti Sains MalaysiaNibong Tebal14300Malaysia Department of electrical and electronics Engineering Faculty of EngineeringAl-Madinah International UniversityKuala Lumpur57100Malaysia

This paper aims to assess the effect of dry band location of contaminated porcelain insulators under various flashover voltages due to *** locations of dry bands are proposed to be tested under different severity of contamination artificially produce using salt deposit density(SDD)sprayed on an *** tests of polluted insulators under proposed scenarios have been *** flashover voltage of clean insulators has been identified as a reference value to analyze the effect of contamination distribution and its *** dry band dimension has been taken into consideration in experimental *** flashover voltage has been predicted using an artificial neural network(ANN)technique based on the laboratory test *** ANN approach is constructed with five input data(geometry the insulator and parameters of contamination)and flashover voltage as the output of the *** indicated that the pollution distribution based on the proposed scenario has a significant influence on the flashover voltage *** of the ANN model reveals that the relative error values between the experimental results and the prediction appeared to be within 5%.This indicates the significant efficiency of the ANN technique in predicting the flashover voltage insulator under test.

关键词： Insulator pollution distribution artificial neural network dry band

Shielding Properties of Lead Zinc Borate Glasses

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World Journal of Condensed Matter Physics 2013年第4期3卷 198-202页

作者： samir Yousha el-Kameesy Sahar abd el-Ghany Moenis abd el-Hakam Azooz Yaser abd Allah el-Gammam Faculty of Engineering Akhbar El-Youm Academy Cairo Egypt Glass Research Department National Research Center Cairo Egypt Physics Department Faculty of Science Ain Shams University Cairo Egypt Physics Department Faculty of Science Al-Azhar University Cairo Egypt

In the present work, ZnO·PbO·B2O3 glasses are prepared to be used as g-ray shielding materials. The attenuation properties of these glasses with different concentrations of PbO (20% - 70%) have been investigated at photon energies 662, 1173, 1332 and 2614 keV. The optical absorption spectra of some glass samples have been measured from 200 to 1100 nm before and after g-ray irradiation. The analyses of these spectra have been interpreted and discussed.

关键词： Glasses-Ray Shielding Attenuation Coefficient

Antibody to el peptide of hepatitis C virus genotype 4 inhibits virus binding and entry to HepG2 cells in vitro

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World Journal of Gastroenterology 2006年第16期12卷 2530-2535页

作者： Mostafa K el-Awady Ashraf A Tabll Khaled Atef Samar S Yousef Moataza H Omran Yasmin EI-abd Noha G Bader-eldin Ahmad M Salem samir F Zohny Wael T EI-Garf Department of Biomedical Technology National Research CenterCairoEgypt Department of Biochemistry Faculty of ScienceAin Shams UniversityCairoEgypt

AIM： To analyze the neutralizing activity of antibodies against E1 region of hepatitis C virus （HCV）. Specific polydonal antibody was raised via immunization of New Zealand rabbits with a synthetic peptide that had been derived from the E1 region of HCV and was shown to be highly conserved among HCV published genotypes. METHODS： Hyper-immune HCV E1 antibodies were incubated over night at 4 ℃ with serum samples positive for HCV RNA, with viral loads ranging from 615 to 3.2 million IU/mL. Treated sera were incubated with HepG2 cells for 90 min. Blocking of viral binding and entry into cells by anti E1 antibody were tested by means of RTPCR and flow cytometry. RESULTS： Direct immunostaining using FITC conjugated E1 antibody followed by Flow cytometric analysis showed reduced mean fluorescence intensity in samples pre-incubated with E1 antibody compared with untreated samples. Furthermore, 13 out of 18 positive sera （72%） showed complete inhibition of infectivity as detected by RT-PCR. CONCLUSION： In house produced E1 antibody, blocks binding and entry of HCV virion infection to target cells suggesting the involvement of this epitope in virus binding and entry. Isolation of these antibodies that block virus attachment to human cells are useful as therapeutic reagents.

关键词： Flow cytometry Hepatitis C virus E1 envelope Therapeutic antibodies Direct immuno-fluorescence HepG2 cells

electromagnetic Wave Propagation in Waveguide Loaded by Split Ring Resonator of Negative Permeability

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Journal of electromagnetic Analysis and Applications 2017年第8期9卷 113-121页

作者： abd el Moneim M. Alaa Mostafa el Said samir F. Mahmoud electronics and Communications Department Faculty of Engineering Cairo University Cairo Egypt

This paper aims to study and analyze the electromagnetic propagation in media with negative transverse permeability and how this leads into some physical phenomena such as the appearance of backward waves and the propagation below cutoff. This study is done through the use of metamaterials of split ring resonators. It is shown that the waveguide dimensions needed to transmit a certain frequency band, can be miniaturized to half its dimension. The analytical determination of the propagation inside a waveguide in the presence of two slabs with dielectric permittivity and negative transverse permeability is derived. Finally it is shown by simulation, how to obtain a backward wave with lower loss than reported earlier in the literature.

关键词： Negative Transverse Permeability Metamaterials Backward Waves Miniaturization of Waveguide Propagation Below Cutoff

The Tumor Infiltrating Lymphocytes (TILs): Did We Find the Missed Piece of the Huge Puzzle?

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Open Journal of Obstetrics and Gynecology 2021年第2期11卷 146-161页

作者： Suzan samir elsharkawy Mohamed abd elrheem Samia abd elrheem Department of Obstetrics and Gynecology Faculty of Medicine Alexandria University Alexandria Egypt

Tumor infiltrating lymphocytes (TILs) are used in evaluating the prognosis and determining treatment of different types of cancer with variable degrees of success. The usage of checkpoint inhibitor immunotherapy as a treatment variety for cancer and Adoptive cell therapy is associated with many complications, severe side effects and high expenses. Recently, in a limited number of metastatic GIT and breast cancers, the identification of T-cell specific against so-called tumor neo-antigens and Adoptive transfer of those lymphocytes resulted in some improvement. In 2020, Detection of a T cell receptor (TCR) in a T cell clone that recognized and killed most human cancer cell lines in vitro via the monomorphic MHC class I-related protein MR1, offers an opportunity for pan-cancer therapy Twenty three years earlier, Moist Heat was used successfully to activate a whole different and new immune response that was able to detect genetic mutation in the affected cancer cells and cured many cases of squamous and basal cell carcinomas. In this commentary review, we aimed to revise the literature for updates of TILs usage in cancer prognosis and treatment.

关键词： Tumor Infiltrating Lymphocytes Cancer Checkpoint Inhibitor Adoptive Cell Therapy T Cell Receptor (TCR) Moist Heat Pan-Cancer Therapy Squamous Cell Carcinoma Basal Cell Carcinomas

Performance Enhancement of Discrete Multi-Tone Systems with a Trigonometric Transform

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International Journal of Communications, Network and System Sciences 2014年第1期7卷 1-9页

作者： samir abd elghafar Salaheldin M. Diab Bassiouny M. Sallam Moawad I. Dessouky el-Sayed M. el-Rabaie Fathi E. abd el-Samie Department of electronics and electrical Communications Faculty of Electronic Engineering Menoufia University Menouf Egypt Department of electronics and electrical Communications Faculty of Electronic Engineering Menoufia University Menouf Egypt Department of electrical Engineering Jazan University Jazan KSA

The sine transform can be used as a tool to conquer the problems of discrete multi-tone (DMT) systems to increase the bit rate. In the proposed discrete sine transform based discrete multi-tone (DST-DMT) system, we make use of the energy compaction property of the DST to reduce the channel effects on the transmitted signals. The mathematical model of the proposed DST system is presented in the paper. Simulation experiments have been carried out to test the effect of the proposed DST-DMT system. The results of these experiments show that the performance of the DST-DMT system is better than that of the traditional FFT-DMT system. The results also show that employing the proposed TEQ in the DST-DMT system can increase the bit rate by about 2.57 Mbps.

关键词： DMT System Discretesine Transform Discrete Fourier Transform Time Domain Equalizer

Limiting the Migration of Bisphenol A from Polycarbonate Using Dielectric Barrier Discharge

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Open Journal of Synthesis Theory and Applications 2014年第3期3卷 27-36页

作者： Emad A. Soliman Ahmed samir Ali M. A. Hassan Mohamed S. Mohy-eldin Gamal abd el-Naim Center of Plasma Technology Al-Azhar University Nasr City Cairo Egypt Department of Chemistry Faculty of Science Al-Azhar University Nasr City Cairo Egypt Department of Polymer Materials Research Advanced Technology and New Materials Research Institute SRTA-City New Bourg El-Arab City Alexandria Egypt

Dielectric barrier discharge is used as a cheap technique for surface treatment of polycarbonate. The discharge system is working in open air at atmospheric pressure. The treatments are carried out at low discharge powers (1.5 and 2 W) for treatment time (2.5 - 15 min). The treated samples show decrease in the contact angle and increase in the crystallinity, thermal stability and surface roughness. The effect of ozone on the increase in the oxygen containing functional groups is discussed. The treatment process shows effective limitation of the migration of bisphenol A from the surface of polycarbonate due to the cross linking. Zero migration of bisphenole A is recorded as the sample is treated for 7.5 min. The treatment process is found to be very efficient with very low cost.

关键词： Dielectric Barrier Discharge Polycarbonate Bisphenole A Surface Treatment