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COVID-19:cardiovascular manifestations-a review of the cardiac effects

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Journal of Geriatric Cardiology 2022年第3期19卷 245-250页

作者： Taha Hatab Mohamad Bahij Moumneh Abdul Rahman Akkawi Mohamad Ghazal samir E.Alam Marwan M.Refaat Department of Internal Medicine Division of CardiologyAmerican University of Beirut Medical CenterBeirutLebanon

The coronavirus first reported in China in November 2002 in the form of atypical pneumonia known as the severe acute respiratory syndrome (SARS).[1] The virus then appeared in 2012 in Saudi Arabia as the Middle East respiratory syndrome (MERS).[2] The year 2020 witnessed a novel β-coronavirus related to the previous detected viruses.[3] It was the severe acute respiratory syndrome coronavirus 2 (SARS-Co V-2)-a positive single stranded RNA virus.

关键词： acute cardiac respiratory

Functionalized liposomes for targeted breast cancer drug delivery

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Bioactive Materials 2023年第6期24卷 401-437页

作者： Janske Nel Kamil Elkhoury Émilie Velot Arnaud Bianchi samir Acherar Grégory Francius Ali Tamayol Stéphanie Grandemange Elmira Arab-Tehrany Universitéde Lorraine LIBioF-54000NancyFrance LAAS-CNRS F-31400ToulouseFrance Universitéde Lorraine CNRSIMoPAF-54000NancyFrance Universitéde Lorraine CNRSLCPMF-54000NancyFrance Universitéde Lorraine CNRSLCPMEF-54000NancyFrance Department of Biomedical Engineering University of Connecticut Health CenterFarmingtonCT06030USA Universitéde Lorraine CNRSCRANF-54000NancyFrance

Despite the exceptional progress in breast cancer pathogenesis,prognosis,diagnosis,and treatment strategies,it remains a prominent cause of female mortality ***,although chemotherapies are effective,they are associated with critical limitations,most notably their lack of specificity resulting in systemic toxicity and the eventual development of multi-drug resistance(MDR)cancer *** have proven to be an invaluable drug delivery system but of the multitudes of liposomal systems developed every year only a few have been approved for clinical use,none of which employ active *** this review,we summarize the most recent strategies in development for actively targeted liposomal drug delivery systems for surface,transmembrane and internal cell receptors,enzymes,direct cell targeting and dual-targeting of breast cancer and breast cancer-associated cells,e.g.,cancer stem cells,cells associated with the tumor microenvironment,etc.

关键词： Liposomes Breast cancer Anti-cancer agents Targeted drug delivery Surface functionalization Receptor-targeted drug delivery

Sex Predictive Value of Frontal Sinus Index Compared to Maxillary Sinus Index:Lateral Cephalometric Study

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Journal of Forensic Science and Medicine 2023年第2期9卷 162-166页

作者： Fatma Mohamed Hassan Maged Nabil Hussein Noran Ayman Abdel Motagally Walaa samir Department of Forensic Medicine and Clinical Toxicology Faculty of MedicineCairo UniversityCairoEgypt Department of Forensic Evidence Abu Dhabi Police GHQAbu DhabiUnited Arab of Emirates Department of Orthodontics Misr University for Science and TechnologyGizaEgypt Department of Oral and Maxillofacial Radiology Faculty of DentistryBeni-Suef UniversityBeni-SuefEgypt

Sex estimation is a crucial step to outline the biological profile of unknown human *** frontal and maxillary sinuses have unique anatomical features and can be utilized efficiently in individual *** studies investigated the frontal and maxillary sinus indexes separately for sex ***,comparing the predictive value of the frontal sinus index(FSI)to the maxillary sinus index(MSI)has not been investigated *** study aimed to evaluate the sex predicting value of FSI compared to MSI assessed on digital lateral *** retrospective cross-sectional study included 88 digital lateral cephalometric images of known sex(44 males and 44 females)and age(20-50 years).Two radiologists measured the maximum anteroposterior sinus width and height of the frontal sinus and maxillary ***,the sinus index was calculated for each *** obtained frontal and maxillary sinuses parameters were tabulated,along with the patient’s sex and age,and subjected to statistical *** results revealed significant differences between males and females regarding frontal sinus width,FSI,and *** discriminant function analysis obtained in this study accurately predicted sex with an overall accuracy of 71.6%(81.8%of males and 61.4%of females)using FSI,and 60.2%(63.6%in females and 56.8%in males)using *** and maxillary sinus indexes can be useful tools for sex *** function equations were developed for both the frontal and maxillary sinus indexes with higher accuracy rates for FSI compared to MSI.

关键词： Cephalometry discriminant analysis paranasal sinuses sex prediction sinus index

Pancreatic pseudocyst

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World Journal of Gastroenterology 2009年第1期15卷 38-47页

作者： samir Habashi Peter V Draganov Department of Gastroenterology Hepatology and Nutrition University of FloridaGainesville Florida 32610 United States

Pancreatic pseudocysts are complications of acute or chronic pancreatitis. Initial diagnosis is accomplished most often by cross-sectional imaging. Endoscopic ultrasound with fine needle aspiration has become the preferred test to help distinguish pseudocyst from other cystic lesions of the pancreas. Most pseudocysts resolve spontaneously with supportive care. The size of the pseudocyst and the length of time the cyst has been present are poor predictors for the potential of pseudocyst resolution or complications, but in general, larger cysts are more likely to be symptomatic or cause complications. The main two indications for some type of invasive drainage procedure are persistent patient symptoms or the presence of complications (infection, gastric outlet or biliary obstruction, bleeding). Three different strategies for pancreatic pseudocysts drainage are available: endoscopic (transpapillary or transmural) drainage, percutaneous catheter drainage, or open surgery. To date, no prospective controlled studies have compared directly these approaches. As a result, the management varies based on local expertise, but in general, endoscopic drainage is becoming the preferred approach because it is less invasive than surgery, avoids the need for external drain, and has a high long-term success rate. A tailored therapeutic approach taking into consideration patient preferences and involving multidisciplinary team of therapeutic endoscopist, interventional radiologist and pancreatic surgeon should be considered in all cases.

关键词：胰腺假性囊肿导管引流术超声内镜症状持续治疗方法慢性胰腺炎并发症初步诊断

Non-alcoholic fatty liver disease:Dietary and nutraceutical approaches

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Liver Research 2023年第3期7卷 216-227页

作者： Ludovica Cogorno Elena Formisano Andrea Vignati Amalia Prigione Antonio Tramacere Consuelo Borgarelli samir Giuseppe Sukkar Livia Pisciotta Department of Experimental Medicine-Medical Pathophysiology Food Science and Endocrinology SectionSapienza University of RomeRomeItaly Department of Internal Medicine University of GenoaGenoaItaly Dietetics and Clinical Nutrition Unit IRCCS Policlinic Hospital San MartinoGenoaItaly

Non-alcoholic fatty liver disease(NAFLD),defined as the presence of fat accumulation in imaging or histology in more than 5%of hepatocytes and exclusion of other causes for secondary hepatic fat accumulation,is one of the major causes of chronic liver disease *** syndrome is associated with an increased risk of progression from NAFLD to non-alcoholic steatohepatitis(NASH),fibrosis,and forthcoming liver ***,genetic predisposition contributes to the risk of NAFLD *** review explores the role of diets and nutraceuticals in delaying the development and the evolution of NAFLD to chronic liver *** Mediterranean diet,high-protein diet,lowcarbohydrate/high-fat diet,high-carbohydrate/low-fat diet,and intermittent fasting are the dietary approaches investigated given the presence of relevant literature ***,this review focused on nutraceuticals with proven efficacy in ameliorating NAFLD and grouped them into four different categories:plant-based nutraceuticals(Ascophyllum nodosum and Fucus vesiculosus,Silymarin,Berberine,Curcumin,Resveratrol,Nigella sativa,Quercetin),vitamin-like substances(vitamin E,vitamin D,vitamin C,coenzyme Q10,inositol),fatty acids(omega-3),and microbiota-management tools(probiotics).

关键词： Non-alcoholic fatty liver disease(NAFLD) Metabolic-associated fatty liver disease(MAFLD) Non-alcoholic steatohepatitis(NASH) Non-alcoholic fatty liver(NAFL) Diets Nutraceuticals

The Communist Manifesto,170 Years Later

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学术界 2018年第11期 214-227页

作者： samir Amin French Marxian Economist Director of the Third World Forum

No text written in the mid-nineteenth century has held the road until today as well as the Communist Manifesto of *** is no any other text written in the middle of the 21th century which retained validity until this day as well as the Manifesto of the Communist *** today entire paragraphs of the text correspond to the contemporary reality even better than in *** from the premises which were hardly visible in the era,Marx and Engels drew the conclusions which the deployment of 170 years of history fully *** this article I will give further enlightening examples.

关键词： text written century premises

Oscillation of third-order functional dynamic equations on time scales

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Science China Mathematics 2011年第12期54卷 2597-2614页

作者： SAKER samir H. College of Science Research Centre King Saud University P.O. Box 2455 Riyadh 11451 Saudi Arabia

We consider the nonlinear functional dynamic equation (p(t)[(r(t)xΔ (t))Δ]γ )Δ + q(t)f (x(τ (t))) = 0, for t≥t0, on a time scale T, where γ > 0 is the quotient of odd positive integers, p, r, τ and q are positive rd-continuous functions defined on the time scale T, and limt→∞τ (t) = ∞. The main aim of this paper is to establish some new sufficient conditions which guarantee that the equation has oscillatory solutions or the solutions tend to zero as t →∞. The main investigation depends on the Riccati substitution and the analysis of the associated Riccati dynamic inequality. Our results extend, complement and improve some previously obtained ones. In particular, the results provided substantial improvement for those obtained by Yu and Wang [J Comput Appl Math, 225 (2009), 531-540]. Some examples illustrating the main results are given.531–540]. Some examples illustrating the main results are given.

关键词：时间尺度动态方程振荡非线性动力学方程 Riccati 三阶连续函数正整数

Global asymptotic stability for a SEI reaction-diffusion model of infectious diseases with immigration

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International Journal of Biomathematics 2018年第3期11卷 289-305页

作者： Salem Abdelmalek samir Bendoukha Department of Mathematics University of Tebessa 12002 Algeria Department of Electrical Engineering College of Engineering Yanbu Taibah University Saudi Arabia

This paper studies the local and global stability of solutions for a spatially spread SEI epidemic model with immigration of individuals using a Lyapunov functional. It is shown that in the presence of diffusion, the unique steady state remains globally stable. Numerical results obtained through Matlab simulations are presented to confirm the findings of this study.

关键词：流行模型稳定性 SEI 传染疾病移民 Lyapunov 反应 Matlab

Recent advances in fermented feeds towards improved broiler chicken performance, gastrointestinal tract microecology and immune responses: A review

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Animal Nutrition 2019年第1期5卷 1-10页

作者： Sugiharto Sugiharto samir Ranjitkar Department of Animal Science Faculty of Animal and Agricultural Sciences Diponegoro University Department of Animal Science (Immunology and Microbiology) Aarhus University

Previously, fermentation has been associated with methods that improve the nutritional value of unconventional feed ingredients for broilers. In recent decades, the fermentation process has been employed to produce functional feeds that have the potential to improve broiler gastrointestinal tract microecology, health and production performance. Some of the functional ingredients found in fermented feed include lactic acid bacteria(LAB), lactic acid and other organic acids, and appear to play major roles in determining the beneficial effects of fermented feed on broiler gut health and performance. Unlike the pig, the available literature on broiler fermented feed is still rather limited. This review describes recent advances in the use of fermented feed(on the basis of conventional and unconventional feed ingredients) in broilers. Similarly, this review also shows that additional research is necessary to exploit fermented feed as a viable food source in broiler nutrition.

关键词： Broiler Fermented feed Growth performance Gut health Immunity