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Wood By-Products as UV Protection:A Consequence Review

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Journal of Renewable Materials 2024年第4期12卷 699-720页

作者： Naglaa Salem El‑Sayed Mohamed Hasanin samir Kamel Cellulose and Paper Department National Research CentreCairo12622Egypt

In recent decades,the ozone layer has suffered considerable damage,increasing the entry of ultraviolet(UV)light into the atmosphere and reaching the earth’s surface,negatively affecting ***,researchers aimed to solve this problem by synthesizing advanced UV-shielding *** the other hand,developing an easy and green strategy to prepare functional materials with outstanding properties based on naturally abundant and environmentally friendly raw materials is highly desirable for sustainable *** biomass-derived materials are sustainable and biodegradable,they present a promising substitute for petroleum-based *** three main structural constituents of the plant biomass-based materials that are naturally available are cellulose,hemicellulose,and *** review details current developments using wood-based products such as cellulose,hemicellulose,and lignin in UV-shielding *** will start with assembling the structure and chemistry of cellulose,hemicellulose,and lignin,followed by their contributions to preparing UV-shielding ***,it will briefly discuss the different processing methods for the design of UV-shielding *** wood by-products offer additional opportunities to use the whole tree harvest.

关键词： UV-shielding wood cellulose lignin hemicellulose sunlight protection

Controlled Synthesis of Bismuth Oxyhalides-based Nanomaterials and Their Catalytic Applications

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Controlled Synthesis of Bismuth Oxyhalides-based Nanomateria...

作者： Ahmad samir Karimi Haqmal 北京化工大学

学位级别：硕士

Impact of cytochrome P450 2C19*2 polymorphism on the clinical cardiovascular events after stent implantation in patients receiving clopidogrel of a southern Tunisian region

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World Journal of Cardiovascular Diseases 2013年第1期3卷 4-10页

作者： Leila Abid Lobna Laroussi Amine Bahloul Ahmed Siala R. Abdelhédi Najla Kharrat Mourad Hentati samir kammoun Cardiology Department Hedi Chaker Hospital Medicine University of Sfax Sfax Tunisia CBS Center Sfax Tunisia

Introduction: The concept of clopidogrel resistance, first described in biology is being strengthened by recent data from clinical epidemiology. The cardiologists have been sensitized to this concept because of its possible involvement in the occurrence of coronary stent thrombosis. Purpose of the study: The purpose of this study was to investigate the genetic variant of the gene CYP 2C19 inour population and to assess the involvement of this genetic profile in the occurrence of major cardiovascular events (MACE) during the follow-up period. Methods: Our prospective study was conducted between May 2009 and September 2010 including 100 patients admitted to the cardiology department for percutaneous coronary stenting. The patients were divided into 2 groups: those with at least one CYP2C19*2 allele (*2 carriers) and non-carriers. Results: The mean age of our patients was 56.7 years ± 10, 5. No remarkable differences in the baseline characteristics were noted between the two groups. The prevalence of CYP2C19*2 allele in our population was 11.5%. Hospital mortality was estimated at 3%. No statistically significant differences were noted between the two groups regarding the occurrence of intra hospital MACE. The mean follow up was 7.5 ± 4.87 months for the entire study population. The rate of MACE during the follow-up of patients receiving clopidogrel was 8.2% throughout the study population: 5.3% in the *2 non-carriers versus 18.2% in the *2 carriers with a statistically significant difference (p = 0.075) at the risk of error of 10%. Concerning the occurrence of stent thrombosis, there was no significant statistical difference between the two study groups. Conclusion: From these results it is suggested that CYP2C19*2 polymorphism is associated with increase in the occurrence of MACE among Tunisian patients receiving clopidogrel. A larger study is needed to assess the role of genotyping in the evaluation of the phenomenon of clopidogrel resistance.

关键词： Clopidogrel CYP2C19*2 Polymorphism MACE Stent Thrombus Percutaneous Coronary Intervention

Anticoagulation in Pregnant Women with Mechanical Heart Valve Prostheses: 25-Year Experience at a Tertiary Care Hospital in a Developing Country

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World Journal of Cardiovascular Diseases 2014年第6期4卷 287-293页

作者： Ahmed Tounsi Dorra Abid Doulira Louati Souad Mallek Malek Akrout Leila Abid Mohamed Abdennadher Imed Frikha Kais Chaabene Mourad Hentati samir kammoun Cardiology Department Hedi Chaker Hospital Sfax Tunisia Department of Cardiovascular Surgery Habib Bourguiba Hospital Sfax Tunisia Obstetrics and Gynecology Department Hedi Chaker Hospital Sfax Tunisia

The aim of this retrospective study was to compare the different anticoagulation regimens used in pregnant women with prosthetic heart valves. We reviewed 86 pregnancies in 57 women from 1987 to 2011. The patients were divided into two groups: group A (39 pregnancies) had oral acenocoumarol throughout pregnancy;and in group B (47 pregnancies), acenocoumarol was replaced by subcutaneous heparin during the first trimester. Both groups received heparin at the time of delivery. The valves replaced were mitral (59.65%), aortic (12.28%), or both (28.07%). 74 pregnancies (86.04%) resulted in live births, 9 (10.46%) had stillbirths, 1 (1.16%) had spontaneous abortion and 2 (2.32%) underwent therapeutic abortions. The live birth rate was higher in women on heparin (87.23%) compared with those on acenocoumarol (84.61%). No malformations appeared in the 74 newborns, except for one case of hydrocephalus. There was one maternal death due to acute mitral valvular thrombosis while on heparin in the first trimester. Hemorrhagic complications occurred in 13 patients in the postpartum period, 4 of whom required transfusion. No anticoagulant regimen can be said to be entirely safe for use during pregnancy as there is a degree of risk with each regimen. Heparin does not offer a clear advantage over oral anticoagulation in the pregnancy outcome.

关键词： Anticoagulation Pregnancy Mechanical Heart Valve Prostheses Maternal Complications Heparin Acenocoumarol

Engineering nanomedicines for immunogenic eradication of cancer cells:Recent trends and synergistic approaches

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Acta Pharmaceutica Sinica B 2024年第6期14卷 2475-2504页

作者： Ahmed O.Elzoghby Omar samir Hagar E.Emam Ahmed Soliman Riham M.Abdelgalil Yomna M.Elmorshedy Kadria A.Elkhodairy Mahmoud L.Nasr Division of Engineering in Medicine and Division of Renal Medicine Department of MedicineBrigham and Women's HospitalHarvard Medical SchoolBoston 02115MAUSA Cancer Nanotechnology Research Laboratory(CNRL) Faculty of PharmacyAlexandria UniversityAlexandria 21521Egypt

Resistance to cancer immunotherapy is mainly attributed to poor tumor immunogenicity as well as the immunosuppressive tumor microenvironment(TME)leading to failure of immune *** therapeutic strategies including chemotherapy,radiotherapy,photodynamic,photothermal,magnetic,chemodynamic,sonodynamic and oncolytic therapy,have been developed to induce immunogenic cell death(ICD)of cancer cells and thereby elicit immunogenicity and boost the antitumor immune ***,many challenges hamper the clinical application of ICD inducers resulting in modest immunogenic ***,we outline the current state of using nanomedicines for boosting ICD of cancer ***,synergistic approaches used in combination with ICD inducing nanomedicines for remodeling the TME via targeting immune checkpoints,phagocytosis,macrophage polarization,tumor hypoxia,autophagy and stromal modulation to enhance immunogenicity of dying cancer cells were *** further highlight the emerging trends of using nanomaterials for triggering amplified ICD-mediated antitumor immune *** reticulum localized ICD,focused ultrasound hyperthermia,cell membrane camouflaged nanomedicines,amplified reactive oxygen species(ROS)generation,metallo-immunotherapy,ion modulators and engineered bacteria are among the most innovative *** challenges,merits and demerits of ICD inducer nanomedicines were also discussed with shedding light on the future role of this technology in improving the outcomes of cancer immunotherapy.

关键词： Immunogenic cell death Immunogenic eradication Nanomedicines Drug delivery Cancer immunotherapy Antitumor immunity T cells Tumor associated antigens Synergistic immune response

Biological characteristics and clinical management of uveal and conjunctival melanoma

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Oncology Research 2024年第8期32卷 1265-1285页

作者： SNJEŽANA KAŠTELAN ANA DIDOVIĆPAVIČIĆ DARIA PAŠALIĆ TAMARA NIKUŠEVA-MARTIĆ samirČANOVIĆ PETRA KOVAČEVIĆ SUZANA KONJEVODA School of Medicine University of ZagrebZagreb10000Croatia Department of Ophthalmology Clinical Hospital DubravaZagreb10000Croatia Department of Ophthalmology Zadar General HospitalZadar23000Croatia Department of Medical Chemistry Biochemistry and Clinical ChemistrySchool of MedicineUniversity of ZagrebZagreb10000Croatia Department of Biology and Genetics School of MedicineUniversity of ZagrebZagreb10000Croatia School of Medicine University of SplitSplit21000Croatia Department of Health Studies University of ZadarZadar23000Croatia

Uveal and conjunctival melanomas are relatively rare tumors;nonetheless,they pose a signiﬁcant risk of mortality for a large number of affected *** pathogenesis of melanoma at different sites is very similar,however,the prognosis for patients with ocular melanoma remains unfavourable,primarily due to its distinctive genetic proﬁle and tumor *** of considerable advances in understanding the genetic characteristics and biological behaviour,the treatment of uveal and conjunctival melanoma remains a formidable *** enhance the prospect of success,collaborative efforts involving medical professionals and researchers in theﬁelds of ocular biology and oncology are *** data show a lack of well-designed randomized clinical trials and limited beneﬁts in current forms of treatment for these *** advancements in the development of effective melanoma therapeutic strategies,all current treatments for uveal melanoma(UM)and conjunctival melanoma(CoM)remain unsatisfactory,resulting in a poor long-term *** trials offer hope for positive outcomes in advanced and metastatic tumors.A more comprehensive understanding of the genetic and molecular abnormalities involved in the development and progression of ocular melanomas opens the way for the development of personalized therapy,with various potential therapeutic targets currently under *** comprehension of the molecular pathogenesis of UM and CoM and their speciﬁcities may aid in the development of new and more effective systemic therapeutic agents,with the hope of improving the prognosis for patients with metastatic disease.

关键词： Uveal melanoma Conjunctival melanoma Genetic characteristics Immune checkpoint inhibitors Target molecular inhibitors

Vibration-based crack prediction on a beam model using hybrid butterfly optimization algorithm with artificial neural network

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Frontiers of Structural and Civil Engineering 2022年第8期16卷 976-989页

作者： Abdelwahhab KHATIR Roberto CAPOZUCCA samir KHATIR Erica MAGAGNINI Structural Section DICEA Polytechnic University of MarcheAncona 60131Italy Faculty of Civil Engineering Ho Chi Minh City Open UniversityHo Chi Minh City 700000Vietnam

Vibration-based damage detection methods have become widely used because of their advantages over traditional *** paper presents a new approach to identify the crack depth in steel beam structures based on vibration analysis using the Finite Element Method(FEM)and Artificial Neural Network(ANN)combined with Butterfly Optimization Algorithm(BOA).ANN is quite successful in such identification issues,but it has some limitations,such as reduction of error after system training is complete,which means the output does not provide optimal *** paper improves ANN training after introducing BOA as a hybrid model(BOA-ANN).Natural frequencies are used as input parameters and crack depth as *** data are collected from improved FEM using simulation tools(ABAQUS)based on different crack depths and locations as the first ***,data are collected from experimental analysis of cracked beams based on different crack depths and locations to test the reliability of the presented *** proposed approach,compared to other methods,can predict crack depth with improved accuracy.

关键词： damage prediction ANN BOA FEM experimental modal analysis

Quasi Controlled K-Metric Spaces over C^(*)-Algebras with an Application to Stochastic Integral Equations

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Computer Modeling in Engineering & Sciences 2023年第6期135卷 2649-2663页

作者： Ouafaa Bouftouh samir Kabbaj Thabet Abdeljawad Aziz Khan Department of Mathematics Laboratory of Partial Differential EquationsAlgebra and Spectral GeometryFaculty of SciencesIbn Tofail UniversityKenitraBP 133Morocco Department of Mathematics and Sciences Prince Sultan UniversityP.O.Box 66833Riyadh11586Saudi Arabia Department of Medical Research China Medical UniversityTaichung40402Taiwan

Generally,the field of fixed point theory has attracted the attention of researchers in different fields of science and engineering due to its use in proving the existence and uniqueness of solutions of real-world dynamic models.C^(∗)-algebra is being continually used to explain a physical system in quantum field theory and statistical mechanics and has subsequently become an important area of *** concept of a C^(∗)-algebra-valued metric space was introduced in 2014 to generalize the concept of metric *** fact,It is a generalization by replacing the set of real numbers with a C^(∗)-*** that,this line of research continued,where several fixed point results have been obtained in the framework of C^(∗)-algebra valued metric,aswell as(more general)C^(∗)-algebra-valued b-metric spaces andC^(∗)-algebra-valued extended b-metric *** recently,based on the concept and properties of C^(∗)-algebras,we have studied the quasi-case of such spaces to give a more general notion of relaxing the triangular inequality in the asymmetric *** this paper,we first introduce the concept of C^(∗)-algebra-valued quasi-controlledK-metric spaces and prove some fixed point theorems that remain valid in this *** support our main results,we also furnish some exampleswhichdemonstrate theutility of ***,as an application,we useour results to prove the existence and uniqueness of the solution to a nonlinear stochastic integral equation.

关键词： C^(*)-algebra-valued quasi controlled K-metric spaces left convergence right convergence fixed point contraction

Development of Magnetite/Graphene Oxide Hydrogels from Agricultural Wastes for Water Treatment

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Journal of Renewable Materials 2022年第7期10卷 1889-1909页

作者： Hebat-Allah STohamy Mohamed El-Sakhawy samir Kamel Cellulose and Paper Department National Research CentreCairo12622Egypt

A novel magnetic hydrogel loaded with graphene oxide(GO)was developed in this ***,GO was prepared from bagasse through a single step via oxidation in the presence of ferrocene under muffled atmospheric conditions,followed by the loading of different amounts of magnetite onto GO via co-precipitation reaction of iron onto GO ***,the 2-acrylamido-2-methyl-1-propane sulfonic acid was grafted onto carboxymethyl cellulose in the presence of magnetite GO and N,N′-methylenebisacrylamide as crosslinker yielded *** structure,morphological,and thermal behavior of the prepared hydrogels were *** addition,the adsorption performance of Ni(Ⅱ)ions from aqueous media by the prepared hydrogels was investigated as a function of temperature,time,and concentration of adsorbate in a batch *** results demonstrated a remarkable enhancement in the adsorption process of Ni(Ⅱ)(Removal efficiency=98.82%).All isotherms were found to fit the Langmuir model *** adsorption properties of both magnetic GO and magnetic hydrogel showed promising properties as green and cheap adsorbents.

关键词： Magnetite graphene oxide hydrogel Ni(Ⅱ)adsorption kinetic models thermodynamics