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SIMAD:Secure Intelligent Method for IoT-Fog Environments Attacks Detection

Computers, Materials & Continua 2022年第2期70卷 2727-2742页

作者： Wided Ben Daoud sami mahfoudhi NTS’Com Research Unit SfaxTunisia Department of MIS CBEQassim UniversityBuraidahAl QassimKSA

The Internet of Thing IoT paradigm has emerged in numerous domains and it has achieved an exponential ***,alongside this advancement,IoT networks are facing an ever-increasing rate of security risks because of the continuous and rapid changes in network *** order to overcome these security challenges,the fog system has delivered a powerful environment that provides additional resources for a more improved data ***,because of the emerging of various breaches,several attacks are ceaselessly emerging in IoT and Fog ***,the new emerging applications in IoT-Fog environment still require novel,distributed,and intelligent security models,controls,and *** addition,the ever-evolving hacking techniques and methods and the expanded risks surfaces have demonstrated the importance of attacks detection *** proves that even advanced solutions face difficulties in discovering and recognizing these small variations of *** fact,to address the above problems,Artificial Intelligence(AI)methods could be applied on the millions of terabytes of collected information to enhance and optimize the processes of IoT and fog *** this respect,this research is designed to adopt a new security scheme supported by an advanced machine learning algorithm to ensure an intelligent distributed attacks detection and a monitoring process that detects malicious attacks and updates threats signature databases in IoTFog *** evaluated the performance of our distributed approach with the application of certain machine *** experiments show that the proposed scheme,applied with the Random Forest(RF)is more efficient and provides better accuracy(99.50%),better scalability,and lower false alert *** this regard,the distribution character of our method brings about faster detection and better learning.

关键词： Attack detection Fog IoT network machine learning distributed mechanism

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Isolated Tracheobronchial Amyloidosis

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International Journal of Clinical Medicine 2015年第9期6卷 643-645页

作者： Madiha mahfoudhi Imen Gorsane sami Turki Taieb Ben Abdallah Department of Internal Medicine A Charles Nicolle Hospital Tunis Tunisia

The tracheobronchial amyloidosis is a rarely localized form. It may manifest as a cancer. Only histological results allow diagnosis confirmation. A 68-year-old man was admitted for exploration of a low abundance hemoptysis. The chest radiograph was normal. CT scan objectified thickening of the walls of the trachea and bronchi which are the seat of calcifications. Bronchoscopy found a burgeoning infiltrative lesion training the right side face of the trachea and the anterior edge of the hull. Histological results confirmed tracheobronchial amyloidosis. Typing of this amyloidosis concluded to AL form. The study of amyloid extension lesion was negative. Immunoelectrophoresis of proteins in the blood and urine was normal. The patient was sent to receive external beam radiation to prepare for endoscopic surgical removal. Post-operative suites were marked by a complete resolution of clinical signs particularly hemoptysis with a follow-up of two years.

关键词： Amyloidosis Trachea Biopsy

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Autoimmune Hepatitis-Primary Biliary Cirrhosis: Overlap Syndrome Concomitant with Unexpected Myasthenia and Thymoma

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Open Journal of Clinical Diagnostics 2015年第1期5卷 20-23页

作者： mahfoudhi Madiha Mamlouk Habiba Turki sami Kheder Adel Department of Internal Medicine A. Charles Nicolle Hospital Tunis Tunisia

The myasthenia gravis is an autoimmune disease which can be associated frequently with a thymoma and also with autoimmune pathologies. We report the case of a 64-year-old man affected an overlap syndrome corresponding to the association of autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC). He also presented concomitant myasthenia gravis and thymoma. The physical examination notes only a disturbed voice. The liver tests showed: alkaline phosphatase 600 U/l, alanine aminotransferase 1280 U/l, and aspartate aminotransferase 985 U/l. Viral serologies of hepatitis were all negative, as well as antinuclear, antimitochondrial and antismooth muscle antibodies. The diagnosis of an overlap syndrome was posed according to the biological and hepatic histhological results. An associated myasthenia was confirmed by the results of the EMG and the positivity of the anti-acetylcholine receptor antibody. A chest CT revealed a thymoma. The treatment consisted of ursodeoxycholic acid, prednisone, azathioprine and pyridostigmine. And the patient improved his voice and the liver function. Thymectomy was practiced without incidents.

关键词： Overlap Syndrome Myasthenia Thymoma

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Kikuchi-Fujimoto Disease Mimicking Tuberculosis

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International Journal of Clinical Medicine 2015年第10期6卷 725-728页

作者： Madiha mahfoudhi Imen Gorsane sami Turki Taieb Ben Abdallah Department of Internal Medicine A Charles Nicolle Hospital Tunis Tunisia

A 32-year-old woman presented with a fever and cervical lymphadenopathies. The research for Mycobacterium tuberculosis was negative. Tuberculin skin test was positive. Laboratory investigations showed an elevated erythrocyte sedimentation rate and a normal white blood cell count. Bacteriological and viral investigations were negative. Quantiferon-Tb Gold test was indeterminate. Thraco-abdominal and pelvic computed tomography, FDG-PET and gallium scintigraphy revealed no abnormalities. Histological study of cervical lymph node biopsy found signs in favor of histiocytic necrotizing lymphadenitis. There were no epithelioid cell granulomas. A test tuberculosis treatment was refused by the patient. The evolution was marked by spontaneous clinical and biological resolution in fifty days. The negative Lowenstein-Jensen culture eliminated formally the tuberculosis. KFD was thus the most likely diagnosis.

关键词： Kikuchi-Fujimoto Disease Mycobacterium tuberculosis Lymphadenitis Histology

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Systemic Sarcoidosis Revealed by a Nasal Lesion: A Case Report

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International Journal of Clinical Medicine 2015年第4期6卷 257-261页

作者： Madiha mahfoudhi Khaled Khammassi sami Turki Mamia Ben Salah Department of Internal Medicine A Charles Nicolle Hospital Tunis Tunisia Department of Oto-Rhino-Laryngology Charles Nicolle Hospital Tunis Tunisia

A 62-year-old man presented with bilateral nasal obstruction and recurrent epistaxis episodes. Physical examination revealed normal body temperature and free cervical lymph nodes areas. Nasal endoscopy found a congestive nasal mucosa associated to bilateral inferior turbinate hypertrophy with a granular aspect of the right inferior turbinate. The biological examination showed lymphopenia, inflammatory syndrome, high serum level of angiotensin-converting enzyme and β2 microglobulin. Tuberculin skin test and Quantiferon gold were negative. The nasal and accessory salivary gland biopsies revealed granulomatous giant cell lesions non-caseating evoking systemic sarcoidosis. Ziehl-Neelsen staining and Lowenstein culture were negative. The diagnosis was systemic sarcoidosis revealed by nasal localization. The systemic extension research was negative. The treatment was based on corticosteroids (1 mg/kg/day) and gradual degression doses associated to a local nasal corticosteroid. The outcome was favorable with improvement of nasal obstruction and disappearance of initial lesions. The follow-up was 2 years.

关键词： Sarcoidosis Nose Granuloma Corticosteroids

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Relapsing Polychondritis Associated with Myelodysplastic Syndrome

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Open Journal of Clinical Diagnostics 2015年第1期5卷 10-13页

作者： mahfoudhi Madiha Mamlouk Habiba Lahiani Rym Turki sami Kheder Adel Department of Internal Medicine A Charles Nicolle Hospital Tunis Tunisia

A 62-year-old man had arthritis and an infiltrated purpuric eruption of the legs. He presented then a cyanosis and aches of the left ear’s pinna with a voice disturbance and an inflammatory aspect of the nose. He had an anemia and a thrombopenia. The infectious and auto-immune research was negative. The laryngo-tracheal scan revealed calcifications of the larynx, the trachea and the initial portion of bronchi. Moreover, the biopsy from ear’s pinna cartilage confirmed the diagnosis of chondritis and peri-chondritis. He was thus considered to have the association with relapsing polychondritis and a myelodysplastic syndrome. The patient was treated with corticosteroids and iterative transfusions. The articular and skinny patient’s symptoms completely resolved. The anemia and the thrombopenia were partially improved. The relapsing polychondritis can be considered as paraneoplastic complication in the context of a myelodysplastic syndrome or as a fortuitous association. The mechanism of such an association remains unknown.

关键词： Relapsing Polychodritis Biopsy Myelodysplastic Syndrome Prognosis

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Adult Onset Still’s Disease

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International Journal of Clinical Medicine 2015年第10期6卷 716-724页

作者： Madiha mahfoudhi Imen Gorsane Rafik Shimi sami Turki Taieb Ben Abdallah Department of Internal Medicine A Charles Nicolle Hospital Tunis Tunisia

The adult onset Still’s disease is a rare affection characterised by occurrence of fever, arthralgia or arthritis and evanescent cutaneous eruption. Multiple other systemic lesions make the diagnosis more difficult. Several diagnostic criteria were formulated to confirm this disease. The physiopathology of the adult onset Still’s disease is not well elucidated. However, several studies based on new facts in physiopathology, improved the therapy of refractory forms for which the biotherapy was an interesting alternative. The TNF alpha receptor antagonists are efficient on systemic and articular manifestations of this disease and allow a corticosteroid’s saving. Tocilizumab (interleukin 6 receptor antagonist), and Anakinra (interleukin 1 receptor antagonist) are also new promising treatments for resistant forms.

关键词： Adult Onset Still’s Disease Cytokine TNF Alpha Receptor Antagonist Interleukin 6 Receptor Antagonist Interleukin 1 Receptor Antagonist

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Primary Laryngeal Tuberculosis

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International Journal of Clinical Medicine 2015年第4期6卷 249-251页

作者： Madiha mahfoudhi Khaled Khammassi Amel Gaieb Battikh Mamia Ben Salah sami Turki Department of Internal Medicine A. Charles Nicolle Hospital Tunis Tunisia Department of Oto-Rhino-Laryngology Charles Nicolle Hospital Tunis Tunisia

Primary laryngeal tuberculosis is rare. It can manifest as a malignancy delaying the diagnosis and the therapeutic management. We report the case of a 34-year-old immunocompetent man whose plaints were fever, sweat and dysphonia. There were no adenopathy, nor hepatosplenomegaly. Several blood cultures were negative. Laboratory studies showed an inflammatory syndrome. In addition, the bacteriological examinations of sputum and urine in search of Mycobacterium tuberculosis were negative. Laryngoscopy confirmed the presence of a thickness of the right vocal cord and an ulcer in the hemilarynx. The histological examination revealed tuberculoid granulomas suggestive of tuberculosis. The culture from vocal cord tissue for Mycobacterium tuberculosis was positive. No other focus of tuberculosis was found on X-ray and computed tomography. Treatment by a combination of isoniazid, rifampicin, pyrazinamide induced a total resolution of symptoms.

关键词： Larynx Tuberculosis Dysphonia

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Recurrent Hemoptysis in a Young Man

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Open Journal of Internal Medicine 2015年第3期5卷 29-32页

作者： Madiha mahfoudhi Imen Gorsane Mounira El Euch sami Turki Taieb Ben Abdallah Internal Medicine Department Charles Nicolle Hospital Tunis Tunisia

Hughes-Stovin syndrome is a scarce entity associating pulmonary artery aneurysms and deep venous thrombosis. It was considered to be a form of Behcet’s syndrome at its initial feature. We present a case of a 27-year-old man having a Hughes-Stovin syndrome. The patient had a history of left ilio-femoral thrombosis and suffered from recurrent oral ulcers. He presented with recurrent hemoptysis. A giant pulmonary aneurysm was confirmed by chest CT scan. A right femoral thrombosis was shown on the inferior legs doppler ultrasonography. The patient was treated by steroids and cyclophosphamide and proposed to an embolization to prevent recurrence of symptoms.

关键词： Hemoptysis Pulmonary Aneurysm Hughes-Stovin Syndrome

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Brown Tumor of the Maxilla Revealing Primary Hyperparathyroidism

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International Journal of Clinical Medicine 2015年第4期6卷 252-256页

作者： Madiha mahfoudhi Khaled Khamassi Amel Gaieb Battikh Rym Lahiani Turki sami Mamia Ben Salah Department of Internal Medicine A Charles Nicolle Hospital Tunis Tunisia Department of Oto-Rhino-Laryngology Charles Nicolle Hospital Tunis Tunisia

Brown tumor or localized form of osteitis fibrosa cystic is a focal lesion complicating hyperpara-thyroidism. It’s rarely revelatory of the clinical feature and corresponds to a mass with partly cystic and partly solid areas. A 65-year-old man, followed up for hypertension, complained of a progressive swelling in the left paranasal part of the face lasting for 3 months. Physical examination revealed a left paranasal swelling of 4 cm diameter, with a healthy looking skin. CT facial bones found a round formation of 2 cm involving the left maxilla. He received tumor resection by vestibular pathway. Histological examination showed many giant cells. We then discussed the brown tumor diagnosis. The PTH dosage was high: 645 pg/mL (normal: 15 - 68 pg/mL). The serum calcium was in the superior normal limit (100 mg/dL). Cervical ultrasound revealed a bottom left parathyroid nodule. A lower left parathyroidectomy was performed. Histological results confirmed parathyroid adenoma. Monitoring was marked by a marked decrease of the PTH serum level then a return to normal values, a normocalcemia and no recurrence of the maxillary tumor with Recoil of 14 months. Brown tumor of the maxilla is rare and should be considered even in absence of hypercalcemia.

关键词： Hyperparathyroidism Brown Tumor Maxilla

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