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Supercritical Fluid Extraction of Uncrushed Jordanian Olives

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Advances in Chemical Engineering and Science 2012年第3期2卷 413-421页

作者： Awni al-Otoom sameer al-asheh Mamdouh allawzi Khalid Mahshi Nahawand alzenati Bader Banat Bdour alnimr Department of Chemical Engineering Jordan University of Science and Technology Irbid Jordan

Announcement from Editorial Board ? The following article has been retracted due to special reason of the authors. This paper published in Vol.2 No. 3, 2012, has been removed from this site. ? Title: Supercritical Fluid Extraction of Uncrushed Jordanian Olives Authors: Awni al-Otoom, sameer al-asheh, Mamdouh allawzi, Khalid Mahshi, Nahawand alzenati, Bader Banat, Bdour alnimr ? ACES Editorial Board? May 19,

关键词： Supercritical Extraction CO2 Olive Olive Oil

RSPO2 as Wnt signaling enabler: Important roles in cancer development and therapeutic opportunities

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Genes & Diseases 2024年第2期11卷 788-806页

作者： Ankit Srivastava Deeksha Rikhari sameer Srivastava Department of Biotechnology Motilal Nehru National Institute of TechnologyAllahabadUttar Pradesh 211004India

R-spondins are secretory proteins localized in the endoplasmic reticulum and Golgi bodies and are processed through the secretory *** the R-spondin family,RSPO2 has emanated as a novel regulator of Wnt signaling,which has now been acknowledged in numerous in vitro and in vivo *** is an abnormal growth of cells that proliferates and spreads uncontrollably due to the accumulation of genetic and epigenetic factors that constitutively activate Wnt signaling in various types of *** cancer (CRC) begins when cells in the colon and rectum follow an indefinite pattern of division due to aberrant Wnt activation as one of the key ***-long progress in research on R-spondins has demonstrated their oncogenic function in distinct cancer types,particularly *** a critical regulator of the Wnt pathway,it modulates several phenotypes of cells,such as cell proliferation,invasion,migration,and cancer stem cell ***,RSPO mutations,gene rearrangements,fusions,copy number alterations,and altered gene expression have also been identified in a variety of cancers,including *** this review,we addressed the recent updates regarding the recurrently altered R-spondins with special emphasis on the RSPO2 gene and its involvement in potentiating Wnt signaling in *** addition to the compelling physiological and biological roles in cellular fate and regulation,we propose that RSPO2 would be valuable as a potential biomarker for prognostic,diagnostic,and therapeutic use in CRC.

关键词： CRC Gene fusion R-Spondins RSPO2 Therapeutics Wnt signaling

Supercritical fluid extraction of useful compounds from sage

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Supercritical Fluid Extraction of Uncrushed Jordanian Olives

Natural Science（自然科学期刊） 2012年第8期

作者： sameer al-asheh Mamdouh allawzi Awni al-Otoom Hussein allaboun Amani al-Zoubi

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Seasonal Abundance and Diversity of Birds of Prey and Owls in al Wathba Wetland Reserve in Abu Dhabi, UAE

Advances in Chemical Engineering and Science（化学工程与科学期刊） 2012年第3期

作者： Awni al-Otoom sameer al-asheh Mamdouh allawzi Khalid Mahshi Nahawand alzenati Bader Banat Bdour alnimr

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Open Journal of Ecology 2024年第3期14卷 228-244页

作者： Shakeel Ahmed Salim Jáved Shahid B. Khan Eissa al Hammadi Abdullah al Hammadi Nouf sameer alqadi Environment Agency-Abu Dhabi Abu Dhabi United Arab Emirates

Inland wetlands in Abu Dhabi Emirate are wintering and stopover sites for migratory birds of prey. We conducted long-term regular monitoring surveys in al Wathba Wetland Reserve (AWWR) from January 1995 to December 2022. Both diurnal and occasionally nocturnal surveys were undertaken to record the migratory raptors and owls in the Wetland Reserve. During the study, a total of 1282 regular monitoring visits were undertaken and 27 species of diurnal raptors and owls representing five families and three orders were detected. These represent 57% of the total species of birds of prey recorded in the UAE. Overall, 63% of all the species that we observed were Accipitriformes followed by 26% Falconiformes and 11% Strigiformes. We found that changes in mean daily temperature have a positive effect on raptor species diversity and abundance in the Wetland Reserve. The species encounter rate was higher in low temperature as compared to high temperature and overall regression equation was statistically significant F (4, 1126) = 8.49), p = 0.00). However, the numbers of raptors did not vary significantly across the years (p = 0.51). Western Marsh-harrier (Circus aeruginosus) and Greater Spotted Eagle (Clanga clanga) were recorded to be the most abundant species in the wetland reserve followed by Common Kestrel (Falco tinnunculus). However, the encounter rate of globally threatened Greater Spotted Eagle was detected to have significantly decreased since 2016. Moreover, 63% of the species detected were uncommon and rarely recorded such as 1) Saker Falcon 2) Lanner Falcon 3) Long-eared Owl & Merlin, which were the rare records from the wetland reserve. Furthermore, 27 years of regular monitoring in the wetland have yielded diverse diurnal raptors and owl fauna (H) = 0.83, (E) = 1.43 (Shannon Diversity Index). The results demonstrate that long-term monitoring surveys in arid environments are essential to determine the trends in the raptor populations and to document rare and globally

关键词： Wetland Reserve Raptors Abundance Diversity Abu Dhabi Inland Wetland AWWR Greater Spotted Eagle

Utility of Preoperative Positron Emission Tomography (PET) in Localizing Perforator Vessels of Anterolateral Thigh Free Flap

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International Journal of Otolaryngology and Head & Neck Surgery 2024年第4期13卷 275-284页

作者： alexandra McMillan sameer A. alvi Zaid al-Qurayshi Zachary Fleishacker Nitin A. Pagedar Marisa R. Buchakjian Department of Otolaryngology University of Iowa Hospitals and Clinics Iowa City IA USA Division of Otolaryngology-Head & Neck Surgery North Shore University Health System Evanston IL USA Pritzker School of Medicine The University of Chicago Chicago IL USA Holden Comprehensive Cancer Center University of Iowa Iowa City IA USA

Objectives: The anterolateral thigh (alT) flap is often considered the workhorse in soft tissue reconstruction of head and neck defects secondary to trauma, infection, or tumor resection. Despite its many advantages, alT flaps have been criticized due to variability in vasculature, which may result in inadequate or non-existent perforators. This retrospective study aims to investigate the utility and validity of positron emission tomography (PET) scan to identify the location and characteristics of perforators to the alT flap. Methods: We performed a 10-year retrospective review of alT flaps at our institution to identify patients with preoperative PET scans available for analysis. Three reviewers (attending physician, fellow, and resident) were asked to identify the number, location, and characteristics (myocutaneous versus septocutaneous) of alT perforators on imaging, and reviewer agreement was assessed. Results were then compared to available operative data. Results: One hundred twenty-one patients were identified who underwent alT free flap surgery. Thirty-eight preoperative PET scans were identified for review. At least one perforator was identified in 92.1% of scans. Agreement percentages regarding the number of perforators ranged from 53% - 61% whereas agreement regarding the location of a single perforator ranged from 79% - 90%. However, reviewers did not agree regarding the type of perforator, with agreement ranging from 34% - 53%. Poor agreement was observed when compared to intraoperative data, with the number of perforators ranging from 26% - 34% and the type of perforator 11% - 24%. These findings are likely due to insufficient data available in operative reports. Conclusion: although initial studies suggest that PET scan shows promising evidence to support the capacity to preoperatively identify alT perforators, future prospective studies are warranted to fully validate these findings.

关键词： Anterolateral Thigh Flaps Positron Emission Tomography Head and Neck Defects Perforator Mapping

AI-Driven Learning Management Systems:Modern Developments, Challenges and Future Trends during theAge of ChatGPT

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Computers, Materials & Continua 2024年第8期80卷 3289-3314页

作者： sameer Qazi Muhammad Bilal Kadri Muhammad Naveed Bilal AKhawaja Sohaib Zia Khan Muhammad Mansoor alam Mazliham Mohd Su’ud Department of Computer Science Faculty of EngineeringScience and TechnologyIQRA UniversityKarachi75500Pakistan College of Computer and Information Sciences Prince Sultan UniversityRiyadh11586Saudi Arabia Faculty of Engineering Department of Electrical EngineeringIslamic University of MadinahP.O.BOX 170Madinah41411Saudi Arabia Faculty of Engineering Department of Mechanical EngineeringIslamic University of MadinahP.O.BOX 170Madinah41411Saudi Arabia Faculty of Computing Riphah International UniversityIslamabad46000Pakistan Faculty of Computing and Informatics(FCI)Multimedia University Cyberjaya63100Malaysia Faculty of Engineering and Information Technology School of Computer ScienceUniversity of Technology SydneySydneyNSW 2007Australia

COVID-19 pandemic restrictions limited all social activities to curtail the spread of the *** foremost and most prime sector among those affected were schools,colleges,and *** education system of entire nations had shifted to online education during this *** shortcomings of Learning Management Systems(LMSs)were detected to support education in an online mode that spawned the research in Artificial Intelligence(AI)based tools that are being developed by the research community to improve the effectiveness of *** paper presents a detailed survey of the different enhancements to LMSs,which are led by key advances in the area of AI to enhance the real-time and non-real-time user *** AI-based enhancements proposed to the LMSs start from the Application layer and Presentation layer in the form of flipped classroom models for the efficient learning environment and appropriately designed UI/UX for efficient utilization of LMS utilities and resources,including AI-based *** layer enhancements are also required,such as AI-based online proctoring and user authentication using *** extend to the Transport layer to support real-time and rate adaptive encrypted video transmission for user security/privacy and satisfactory working of *** also needs the support of the Networking layer for IP-based geolocation features,the Virtual Private Network(VPN)feature,and the support of Software-Defined Networks(SDN)for optimum Quality of Service(QoS).Finally,in addition to these,non-real-time user experience is enhanced by other AI-based enhancements such as Plagiarism detection algorithms and Data Analytics.

关键词： Learning management systems chatbots ChatGPT online education Internet of Things(IoT) artificial intelligence(AI) convolutional neural networks natural language processing

Noscapine shows antimalarial activity against Plasmodium falciparum 3D7,its clinical isolate Pf140/SS,and Plasmodium berghei ANKA

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Asian Pacific Journal of Tropical Biomedicine 2024年第8期14卷 350-358页

作者： Swaraj Kumar Babu sameer Maharana Satyaranjan Chhatria Dibya Ranjan Sahoo Ashirbad Nanda Satish Kanhar Prativa KBehera Sanjib Mohanty Pradeep Kumar Naik Praveen Kishore Sahu Centre of Excellence in Natural Products and Therapeutics Department of Biotechnology and BioinformaticsSambalpur UniversityJyoti ViharSambalpur OdishaIndia Department of Molecular Biology and Infectious Diseases Community Welfare Society HospitalRourkelaOdishaIndia Molecular&Immunology Laboratory Infectious Disease Biology UnitIspat General HospitalRourkelaOdishaIndia Department of Pharmacy Centurion University of Technology and ManagementBhubaneswarOdishaIndia

Objective:To evaluate the antimalarial activity of noscapine against Plasmodium falciparum 3D7 strain(Pf3D7),its clinical isolate(Pf140/SS),and Plasmodium berghei ANKA(PbA).Methods:Using ring-stage survival assay,phenotypic assessments,and SYBR-green-based fluorescence assay,the antimalarial activities of noscapine were assessed compared with dihydroartemisinin(DHA)in in vivo and in vitro *** addition,hemolysis and cytotoxicity tests were carried out to evaluate its ***-PCR assay was also conducted to determine the effect of noscapine on papain-like cysteine protease Plasmodium falciparum falcipain-2(PfFP-2).Results:The antimalarial efficacy of noscapine against Pf3D7 and Pf140/SS was comparable to DHA,with IC50 values of(7.68±0.88)and(5.57±0.74)nM/mL,respectively,and>95%inhibition of PbA infected *** also showed a safe profile,as evidenced by low hemolysis and cytotoxicity even at high ***,PfFP-2 expression was significantly inhibited in both noscapine-treated Pf3D7 and Pf140/SS(Palarial properties comparable to standard antimalarial DHA with better safety profiles,which may be further explored as a therapeutic candidate for the treatment of malaria.

关键词： Malaria Plasmodium falciparum Plasmodium berghei Noscapine Antimalarial Dihydroartemisinin Cytotoxicity Falcipain-2

Comparative Study of Exhaust Emissions from Diesel and Syngas Powered 3.5 kW Compression Ignition Engine with and without Load

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Journal of Power and Energy Engineering 2024年第8期12卷 30-46页

作者： Benson Kariuki Paul Njogu Joseph Kamau Robert Kinyua sameer Bachani Institute of Energy and Environmental Technology Jomo Kenyatta University of Agriculture & Technology Nairobi Kenya Department of Mechanical and Automotive Engineering Technical University of Mombasa Mombasa Kenya

Despite diesel engines being highly efficient, with low fuel consumption and reduced carbon dioxide emissions, they emit relatively high levels of particulate matter and oxides of nitrogen (NOx) due to high exhaust gas temperatures. Engine emissions show the quality and completeness of combustion. This paper aims to present the results of a study comparing exhaust emissions from a diesel and syngas powered engine. Syngas was produced from co-firing coal and biomass in a gasifier then cleaned, cooled and applied as an alternative fuel in an engine operated from 0 - 100% load. Exhaust-emissions were monitored at this load conditions. The exhaust-temperature was measured using thermocouples and the emission gases were analyzed using Testo 350. The emissions were lower and decreased as the engine load increased, except for sulphur dioxide and NOx. The study shows that levels of carbon monoxide, were higher in a range of 46.5 - 80.2%, while carbon dioxide was 3.3 - 18% higher compared to those from diesel. Hydrocarbon emissions were 480 and 1250 ppm for diesel and syngas respectively. The study reveals that the engine operates optimally at higher loads since hydrocarbons and oxides of carbon are low due to complete combustion at higher temperatures. Exhaust gas temperature was higher in the syngas fuel and increased as the engine load increased in the range of 455.83 - 480.03˚C which influenced the formation of NOx. NOx from diesel was found to be higher, ranging from 32.5 - 40.5%, compared to those from syngas with an engine load of 75%. The study observed that relative to diesel, the emissions of sulfur dioxide at 50% engine load were lower in a range of 23.7 - 57.1%. Emissions of hydrocarbons depended on the degree of substitution of diesel and engine load. The study therefore shows that, relative to diesel, emissions decreased when syngas was used with upgraded syngas from Prosporis juliflora presenting as the best alternative followed by Hyphanae compressa, and last

关键词： Emissions Engine Load Temperature Neat-Diesel Syngas