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The Awareness of Keratoconus among General Population in Saudi Arabia

Open Journal of Ophthalmology 2021年第1期11卷 49-59页

作者： Rahaf Mohammed Alruwaili Abeer Surihan Alharbi Omar Ali Alghamdi Yahya Abdulrahman Alyahya Nouf Mohammed Albalawi sameer sohail alostaz Omar Ahmed Asiri Khalid Alarfaj College of Medicine Jouf University Sakaka Saudi Arabia Ophthalmology Department Ohud Hospital Madina Saudi Arabia Ophthalmology Department King Fahad Hospital Albaha Saudi Arabia Ophthalmology Department Burydah Central Hospital Qassim Saudi Arabia College of Medicine Tabuk University Tabuk Saudi Arabia Batterjee Medical College Jeddah Saudi Arabia Faculty of Medicine Taif University Taif Saudi Arabia Ophthalmology Department Imam Abdulrahman Bin Faisal University Dammam Saudi Arabia

Introduction: Keratoconus (KCN) is one of the degenerative corneal disorders, which causes impairment in normal visual acuity with a higher prevalence in Saudi Arabia. The study aimed to assess the awareness and knowledge regarding KCN, its risk factors, and management among the Saudi population. Materials and Methods: A survey was conducted using a pre-tested and validated questionnaire distributed through online platforms. A mixture of convenience and snowball sampling techniques was adopted for sample collection. Our analysis included a final sample size of 837 participant responses. The questionnaire had items related to sociodemographic characteristics (5 items), knowledge (10 items), and source of information (1 item). The mean knowledge scores were calculated and categorized (good, fair, and poor) to assess each participant’s knowledge. Pearson’s chi-square test was used to determine the statistical association between categorical variables. Results: The mean knowledge score was found to be 4.12 ± 2.6, and 67.5% of the participants showed “poor” scores. There was no statistically significant association of knowledge scores observed with any of the sociodemographic details. It was agreed by 76% and 42.5% that genetic predisposition and chronic eye inflammation could predispose to KCN. Only 38.1% (n = 157) agreed that KCN could be treated with optical glasses or contact lenses in the initial stages. Conclusion: The knowledge regarding KCN was not satisfactory among our study population. There is a need to create an increased level of awareness for KCN. Health awareness programs and community campaigns should be organized to raise awareness regarding KCN and better eye health care utilization.

关键词： Ophthalmology Inflammation Keratoconus Blindness

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Hyoscine for polyp detection during colonoscopy: A meta-analysis and systematic review

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World Journal of Gastrointestinal Endoscopy 2014年第11期6卷 549-554页

作者： Imran Ashraf sohail Ashraf sameer Siddique Douglas L Nguyen Abhishek Choudhary Matthew L Bechtold Department of Medicine University of Mis-souri Columbia MO 65212 United States Department of Gastroenterology and Hepatology Central Manchester University Hospitals M139WL Manchester United Kingdom Department of Medicine University of California Irvine CA 92868 United States

AIM: To assess the role of hyoscine for polyp detectionduring ***: Studies(randomized controlled trials orRCTs) that compared the use of hyoscine vs no hyo-scine or placebo for polyp detection during colonoscopywere included in our analysis. A search on multiple da-tabases was performed in September 2013 with searchterms being "hyoscine and colonoscopy", "hyoscineand polyp", "hyoscine and adenoma", "antispasmoticand colonoscopy", "antispasmotic and adenoma", and"antispasmotic and polyp". Jadad scoring was used toassess the quality of studies. The efficacy of hyoscinewas analyzed using Mantel-Haenszel model for polypand adenoma detection with odds ratio(OR). The I2measure of inconsistency was used to assess hetero-geneity(P 50%). Statistical analysis was performed by RevMan 5.1. Funnel plots was used to assess publication ***: The search of the electronic databases identified 283 articles. Of these articles, eight published RCTs performed at various locations in Europe, Asia, and Australia were included in our meta-analysis, seven published as manuscripts and one published as an ab-stract(n = 2307). All the studies included patients with a hyoscine and a no hyoscine/placebo group and were of adequate quality(Jadad score ≥ 2). Eight RCTs as-sessed the polyp detection rate(PDR)(n = 2307). The use of hyoscine demonstrated no statistically significant difference as compared to no hyoscine or placebo for PDR(OR = 1.06; 95%CI: 0.89-1.25; P = 0.51). Five RCTs assessed the adenoma detection rate(ADR)(n = 2015). The use of hyoscine demonstrated no statisti-cally significant difference as compared to no hyoscine or placebo for ADR(OR = 1.12; 95%CI: 0.92-1.37; P = 0.25). Furthermore, the timing of hyoscine admin-istration(given at cecal intubation or pre-procedure) demonstrated no differences in PDR compared to no hyoscine or placebo. Publication bias or heterogeneity was not observed for any of the ***: Hyoscine use in pa

关键词： Hyoscine Antispasmodic Polyp detection Colonoscopy

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