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Adenocarcinoma arising at ileostomy sites:Two cases and a review of the literature

World Journal of Gastrointestinal Surgery 2015年第6期7卷 94-97页

作者： Lauren Procaccino sameer rehman Alexander Abdurakhmanov Peter McWhorter Nicholas La Gamma Madhu C Bhaskaran James Maurer Gregory M Grimaldi Horacio Rilo Jeffrey Nicastro Gene Coppa Ernesto P Molmenti John Procaccino Department of Surgery North Shore University Hospital

Total colectomy with ileostomy placement is a treatment for patients with inflammatory bowel disease or familial adenomatous polyposis(FAP). A rare and late complication of this treatment is carcinoma arising at the ileostomy site. We describe two such cases: a 78-year-old male 30 years after subtotal colectomy and ileostomy for FAP, and an 85-year-old male 50 years after colectomy and ileostomy for ulcerative colitis. The long latency period between creation of the ileostomies and development of carcinoma suggests a chronic metaplasia due to an irritating/inflammatory causative factor. Surgical excision of the mass and relocation of the stoma is the mainstay of therapy, with possible benefits from adjuvant chemotherapy. Newly developed lesions at stoma sites should be biopsied to rule out the possibility of this rare ileostomy complication.

关键词： Ileostomy Carcinoma Adenocarcinoma Familial adenomatous polyposis Inflammatory boweldisease Complication of ileostomy

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Genes and Transcriptional Factors in Chili Plant with Aspect to Metabolism and Resistance against Virus, Bacteria and Fungi： A Review

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Journal of Agricultural Science and Technology(B) 2014年第7期4卷 509-517页

作者： Arfan Ali Muhammad Sarmad Iftikhar Muhammad Munawar Muqadas Aleem Sajed Ali Saira Azam Idrees Ahmad Nasir Tayyab Husnain Umair Majid Muhammad sameer Akram Tajasar Kamran Shehzad Bajwa Tahir rehman Samiullah National Centre of Excellence in Molecular Biology University of the Punjab Lahore 53700 Pakistan Department of Plant Breeding and Genetics University of Agriculture Faisalabad 38000 Pakistan

These days, there is a lot of discussion about genetically modified plants. There are different schools of thoughts in public, and some people adjusted while others are reluctant to accept genetically modified organism foods. Many vegetables are transformed and are used in daily life. Chili is one of those which is genetically modified and used in our food. Race specific genes can be used more efficiently for disease resistance and improving metabolic pathways. Different genes and transcriptional factors are available in Capsicum for this purpose. We can optimize and use the better expressed genes while engineering the chili plants, Genetic modifications causing significant changes are related with metabolism, which cause disease resistance.

关键词： Transcriptional factors chili plant metabolism resistance in chilies.

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