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Effectiveness of BNT162b2 Vaccine against Critical Covid-19 in Adolescents

四川生理科学杂志 2021年第11期43卷 1723-1723页

作者： samantha M Olson From the Covid-19 Response Team Centers for Disease Control and Prevention (S.M.O. A.M.P. L.D.Z. A.P.C. M.M.P.) and the Center for Childhood Infections and Vaccines of Children’s Healthcare of Atlanta and the Department of Pediatrics Emory University School of Medicine (S.K.) — both in Atlanta the department of Anesthesiology Critical Care and Pain Medicine Boston Children’s Hospital (M.M.N. A.G.R.) and the Departments of Anaesthesia and Pediatrics Harvard Medical School (A.G.R.) — both in Boston the division of Pediatric Infectious diseases Department of Pediatrics Vanderbilt University Medical Center Nashville (N.B.H.) the department of Pediatrics Baylor College of Medicine Immunization Project Texas Children’s Hospital Houston (J.A.B. L.C.S.) and the Department of Pediatrics Division of Critical Care Medicine University of Texas Southwestern Children’s Medical Center Dallas Dallas (M.M.) the division of Infectious diseases Children’s Hospital Los Angeles and Departments of Pediatrics and Molecular Microbiology and Immunology University of Southern California Los Angeles (P.S.P.) the Division of Pediatric Hospital Medicine UC San Diego–Rady Children’s Hospital San Diego (M.A.C.) the Division of Critical Care Medicine UCSF Benioff Children’s Hospital Oakland (N.Z.C.) and the Department of Pediatrics Divisions of Critical Care Medicine and Allergy Immunology and Bone Marrow Transplant University of California San Francisco San Francisco (M.S.Z.) — all in California Section of Pediatric Critical Care Department of Pediatrics Arkansas Children’s Hospital Little Rock (K.I.) the department of Pediatrics University of North Carolina at Chapel Hill Children’s Hospital Chapel Hill (T.C.W. S.P.S.) the department of Pediatrics Section of Critical Care Medicine University of Colorado School of Medicine and Children’s Hospital Colorado Aurora (A.B.M.) the division of Pediatric Critical Care Medicine Medical University of South Carolina Charleston (E.H.M.) the department of

Background:The increasing incidence of pediatric hospitalizations associated with coronavirus disease 2019(Covid-19)caused by the B.1.617.2(delta)variant of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)in the United States has offered an opportunity to assess the real-world effectiveness of the BNT162b2 messenger RNA vaccine in adolescents between 12 and 18 years of ***:We used a case-control,test-negative design to assess vaccine effectiveness against Covid-19 resulting in hospitalization,admission to an intensive care unit(ICU),the use of life-supporting interventions(mechanical ventilation,vasopressors,and extracorporeal membrane oxygenation),or *** July 1 and October 25,2021,we screened admission logs for eligible case patients with laboratory-confirmed Covid-19 at 31 hospitals in 23 *** estimated vaccine effectiveness by comparing the odds of antecedent full vaccination(two doses of BNT162b2)in case patients as compared with two hospitalbased control groups:patients who had Covid-19-like symptoms but negative results on testing for SARS-CoV-2(test-negative)and patients who did not have Covid-19-like symptoms(syndrome-negative).

关键词： vaccine doses acute

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Universal Service Policy in Taiwan:A Case Study of Telecommunications in an Era of Liberalization and Technological Convergence

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北大法律评论 2002年第1期3卷 209-252页

作者： samantha Shiau-Ping Lee J.S.d.candidate of Stanford law School.Special thanks to Professor Rogelio Perez-Perdomo and Professor John H.Barton for their intellectual support and invaluable comments.

*** this highly competitive information age,the telecommunications infrastructure isthe nerve center of every country. Among the numerous telecommunications policiesworld-wide,universal service policy is a useful means to gauge the effectiveness of anygiven country’s response to rapidly changing global conditions and its own social,economic,political,and technological *** universal service refers to

关键词：法律评论北大明山识别码面理叩问义耳代工环月工尺

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Effect of localized oil spills on Atlantic loggerhead population dynamics

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Open Journal of Ecology 2012年第3期2卷 109-114页

作者： Margaret-Rose Leung Melissa Marchand samantha Stykel My Huynh José d. Flores department of Mathematics Arizona State University Tempe USA department of Mathematics California State University Bakersfield Bakersfield USA department of Mathematics Luther College Decorah USA department of Mathematics Oregon State University Corvallis USA department of Mathematics The University of South Dakota Vermillion USA

The purpose of this study is to analyze the population dynamics of loggerhead sea turtles (Caretta caretta) affected by localized oil spills. Methods include development of a spatial, stage-classified matrix model parameterized for the following primary loggerhead populations: Gulf of Mexico, western North Atlantic Ocean, and Florida peninsula. Oil spills are simulated deterministically in each population's nesting region, with 1) oil-induced mortality ranging from 25% to 100% and 2) stage classes affected either proportionally or equally. A transient sensitivity analysis was performed to determine the parameters most influential to the population growth rate. Results suggest that increased protection and understanding of young sea turtles found in the Sargasso Sea is essential to the survival of the species. In addition, findings provide insights into the population dynamics of the At- lantic loggerhead turtles and identify conservation measures appropriate in each oil spill case.

关键词： Loggerhead Sea Turtle Oils Spill Matrix Model Simulations Population Ecology

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Identification of a decedent in a 103-year-old homicide case using forensic anthropology and genetic genealogy

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Forensic Sciences Research 2022年第3期7卷 412-426页

作者： Amy R.Michael samantha H.Blatt Mariyam Isa Anthony Redgrave douglas H.Ubelaker department of Anthropology University of New HampshireDurhamNCUSA department of Anthropology Idaho State UniversityPocatelloIDUSA department of Anthropology Texas Tech UniversityLubbockTXUSA Redgrave Research Forensic Services OrangeCAUSA department of Anthropology National Museum of Natural HistorySmithsonian InstitutionWashingtonDCUS

Anthropologists are often the custodians of long-term unidentified human remains though their positions as curators of university or museum skeletal *** factors decrease the solvability of these legacy cases including the passage of time,the loss of provenience for specific cases,and lack of documentation or case *** anthropologists can contribute important information toward identification,it is often necessary to explore novel and cross-disciplinary strategies to resolve difficult cold *** long cold cases,the postmortem interval,in particular,may be difficult to estimate leading to further challenges in achieving *** advances in radiocarbon bomb pulse dating,isotope analysis,and actualistic studies have contributed to positive identification of unidentified human remains in some legacy cases,but may not be available to all forensic practitioners and law enforcement from resource-poor *** resources,as well as collaborating with professionals outside of forensic anthropology,is a useful strategy to pursue when anthropological methods are *** case study presented here demonstrates a collaborative approach between forensic anthropologists,forensic genetic genealogists,and law enforcement in a century-old *** dismembered and mummified parts of a male body were recovered in a remote cave in 1979 and again in *** forensic anthropologists creating and updating the biological profile over the decades from recovery to present,no identification was made until the application of forensic genetic genealogy(FGG)to the case in *** interpretations of bone microstructure and trauma analysis are presented for the case,alongside the historical documentation and“proof of life”evidence used by the genealogy team.A review of the FGG methods underscores the challenges in this case(*** endogamy,multiple aliases used by the victim)and the steps taken toward ***,a co

关键词： Forensic sciences forensic anthropology forensic genetic genealogy human identification cold case investigative genetic genealogy postmortem interval skeletal trauma

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European Species of Hebeloma Section Theobromina

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Fungal diversity 2013年第1期58卷 103-126页

作者： Ursula Eberhardt Henry J.Beker Jan Vesterholt Karolina dukik Grit Walther Jordi Vila samantha Fernández Brime CBS-KNAW Fungal Biodiversity Centre Centraalbureau voor SchimmelculturesUppsalalaan 83584 CT UtrechtNetherlands Rue Père de deken 19 1040 BruxellesBelgium Natural History Museum of denmark Gothersgade 1301123 Copenhagen K.Denmark Microbial Resource Collection Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute and Institute of MicrobiologyDepartment of Microbiology and Molecular BiologyUniversity of JenaBeutenbergstraße 11a07745 JenaGermany department Biologia Vegetal(Botànica) Fac.BiologiaUniversitat de BarcelonaDiagonal 64508028 BarcelonaSpain

This paper addresses section Theobromina within the genus Hebeloma(Agaricales).We recognise seven European species within this section,three of which are described as new:Hebeloma alboerumpens,*** and *** first two of these species appear to be ectomycorrhizal with Cistaceae:Cistus and *** parvicystidiatum is more likely to be in mycorrhizal association with Quercus *** also provide a key to the European species within *** and an updated key of known Hebeloma associates of *** analyses based on multiple loci further illustrate the distinctness of the newly described taxa and provide molecular evidence,supporting the morphological evidence,for the relationship that exists among species of this *** ITS is the only one from the sequenced loci that,alongside with morphology,distinguishes among all of the species of *** section gains most of its molecular support from the MCM7 locus,followed by RPB2.

关键词： Host specificity Fungi Hebeloma plesiocistum Hebeloma theobrominum Hebeloma vesterholtii dNA barcode

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differential responses of carbon and water vapor fluxes to climate among evergreen needleleaf forests in the USA

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Ecological Processes 2016年第1期5卷 91-107页

作者： Pradeep Wagle Xiangming Xiao Thomas E.Kolb Beverly E.law Sonia Wharton Russell K.Monson Jiquan Chen Peter d.Blanken Kimberly A.Novick Sabina dore Asko Noormets Prasanna H.Gowda department of Microbiology and Plant Biology Center for Spatial AnalysisUniversity of OklahomaNormanOK 73019USA Institute of Biodiversity Science Fudan UniversityShanghai 200433China School of Forestry Northern Arizona UniversitylagstaffAZ 86011USA department of Forest Ecosystems and Society Oregon State UniversityCorvallisOR 97331USA Atmospheric Earth and Energy DivisionLawrence Livermore National LaboratoryLivermoreCA 94550USA School of Natural Resources and the Environment and Laboratory of Tree Ring Research University of ArizonaTucsonAZ 85711USA department of Geography Michigan State UniversityEast LansingMI 48824USA department of Geography University of ColoradoBoulderCO 80309USA School of Public and Environmental Affairs Indiana University-BloomingtonBloomingtonIN 47405USA department of Environmental Science Policyand ManagementUniversity of California BerkeleyBerkeleyCA 94702USA department of Forestry and Environmental Resources North Carolina State UniversityRaleighNC 27695USA USdA-ARS Grazinglands Research Laboratory El RenoOK 73036USA

Introduction:Understanding the differences in carbon and water vapor fluxes of spatially distributed evergreen needleleaf forests(ENFs)is crucial for accurately estimating regional or global carbon and water budgets and when predicting the responses of ENFs to current and future ***:We compared the fluxes of ten AmeriFlux ENF sites to investigate cross-site variability in net ecosystem exchange of carbon(NEE),gross primary production(GPP),and evapotranspiration(ET).We used wavelet cross-correlation analysis to examine responses of NEE and ET to common climatic drivers over multiple timescales and also determined optimum values of air temperature(T_(a))and vapor pressure deficit(VPd)for NEE and ***:We found larger differences in the NEE spectra than in the ET spectra across sites,demonstrating that spatial(site-to-site)variability was larger for NEE than for *** NEE and ET were decoupled differently across ENF sites because the wavelet cospectra between ET and climate variables were similar at all sites,while the wavelet cospectra between NEE and climate variables were higher(i.e.,closer coupling between NEE and climatic drivers)in semi-arid and Mediterranean sites than in other *** water use efficiency(EWUE)based on annual GPP/ET ranged from 1.3±0.18 to 4.08±0.62 g C mm^(−1) ET,while EWUE based on annual net ecosystem production(NEP)/ET ranged from 0.06±0.04 to 1.02±0.16 g C mm^(−1) ET)among *** of NEE and ET to T_(a) varied across climatic *** particular,for ENF sites in semi-arid and Mediterranean climates,the maximum NEE and ET occurred at lower ranges of T_(a) than in sites with warm and humid *** optimum T_(a) and VPd values were higher for ET than for NEE,and ET was less sensitive to high values of T_(a) and ***:Large spatial variability in carbon and water vapor fluxes among ENFs and large variations in responses of NEE and ET to major climate variables among climatic zones necessitate sub-

关键词： drought Ecosystem water use efficiency Net ecosystem CO_(2)exchange Spatial variability Wavelet cross-correlation analysis

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Comparison of the Rose Bengal Plate and the Complement Fixation Tests with the Tube Agglutination Test for diagnosis of Human Brucellosis

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Open Journal of Clinical diagnostics 2017年第3期7卷 73-82页

作者： Ying-Hock Teng Jung-Jing Teng samantha Chao Hsu Chao Suryakant d. Waghela department of Emergency Medicine School of Medicine Chung Shan Medical University Taiwan department of Emergency Medicine Chung Shan Medical University Hospital Taiwan Residency Program Civil Aviation General Hospital Peking University Health Science Center Beijing China Rice University Houston TX USA HGSC Baylor College of Medicine Houston TX USA Veterinary Research Laboratory Kabete Kenya department of Veterinary Pathobiology Texas A&M University College Station TX USA

Brucellosis is a zoonotic disease of economic importance. The clinical manifestations vary in humans;therefore a good diagnostic test is required to confirm the disease. The serum tube agglutination (SA) test, though still the most widely test used, can be problematic for the diagnosis of chronic infections. The other supplementary tests, such as the complement fixation (CF) test and ELISA, require special equipment, reagents and trained personnel. The Rose Bengal plate (RBP) test has shown potential as a good rapid diagnostic test. This is a report of serum samples from suspected cases of brucellosis that were tested using the RBP, SA and CF tests. The RBP test was shown to have a better relative sensitivity and as good specificity as the SA when compared with the CF test, and may be a useful initial diagnostic test for hospitals in remote rural areas if properly conducted with well stored antigen.

关键词： Brucellosis Human diagnosis Rose Bengal Plate Test

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Prized edible Asian mushrooms: ecology, conservation and sustainability

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Fungal diversity 2012年第5期56卷 31-47页

作者： Peter E.Mortimer samantha C.Karunarathna Qiaohong Li Heng Gui Xueqing Yang Xuefei Yang Jun He Lei Ye Jiayu Guo Huili Li Phongeun Sysouphanthong dequn Zhou Jianchu Xu Kevin d.Hyde Key Laboratory of Biodiversity and Biogeography Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China World Agroforestry Centre East Asia132 Lanhei RoadKunming 650201China Institute of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Mushroom Research Foundation 128 M.3 Ban Pa Deng T.Pa PaeA.Mae TaengChiang Mai 50150Thailand Centre for Mountain Ecosystem Studies Kunming Institute of BotanyChinese Academy of Sciences650201KunmingChina Faculty of Environmental Science and Engineering Kunming University of Science and Technology68 Wenchang RoadYieryi StreetYunnan Province Kunming 650093China

Mushrooms can be found in forests worldwide and have long been exploited as resources in developed economies because of their important agro-industrial,medicinal and commercial *** less developed countries,such as those within the Greater Mekong Subregion,wild harvesting and mushroom cultivation provides a much-needed alternative source of income for rural ***,this has led to over-harvesting and ultimately environmental degradation in certain areas,thus management guidelines allowing for a more sustained approach to the use of wild mushrooms is *** article addresses a selection of the most popular and highly sought after edible mushrooms from Greater Mekong Subregion:Astraeus hygrometricus,Boletus edulis,Morchella conica,Ophiocordyceps sinensis,Phlebopus portentosus,Pleurotus giganteus,Termitomyces eurhizus,Thelephora ganbajun,Tricholoma matsuake,and Tuber indicum in terms of value,ecology and *** greatest threat to these and many other mushroom species is that of habitat loss and over-harvesting of wild stocks,thus,by creating awareness of these issues we wish to enable a more sustainable use of these natural *** our paper provides baseline data for these fungi so that future monitoring can establish the effects of continued harvesting on mushroom populations and the related host species.

关键词： Mushroom species Greater Mekong Sub-region Medicinal foods Non-timber forest products

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Lipocalin 2 stimulates bone fibroblast growth factor 23 production in chronic kidney disease

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Bone Research 2021年第3期9卷 385-395页

作者： Guillaume Courbon Connor Francis Claire Gerber samantha Neuburg Xueyan Wang Emily Lynch Tamara Isakova Jodie LBabitt Myles Wolf Aline Martin Valentin david division of Nephrology and Hypertension Department of Medicineand Center for Translational Metabolism and HealthInstitute for Public Health and MedicineNorthwestern University Feinberg School of MedicineChicagoILUSA Nephrology division Program in Membrane BiologyMassachusetts General HospitalHarvard Medical SchoolBostonMAUSA division of Nephrology Department of Medicineand Duke Clinical Research InstituteDuke University School of MedicineDurhamNCUSA

Bone-produced fibroblast growth factor 23(FGF23)increases in response to inflammation and iron deficiency and contributes to cardiovascular mortality in chronic kidney disease(CKd).Neutrophil gelatinase-associated lipocalin(NGAL or lipocalin 2;LCN2 the murine homolog)is a pro-inflammatory and iron-shuttling molecule that is secreted in response to kidney injury and may promote CKd *** investigated bone FGF23 regulation by circulating *** 23 weeks,Col4a3KO mice showed impaired kidney function,increased levels of kidney and serum LCN2,increased bone and serum FGF23,anemia,and left ventricular hypertrophy(LVH).deletion of Lcn2 in CKd mice did not improve kidney function or anemia but prevented the development of LVH and improved survival in association with marked reductions in serum ***2 deletion specifically prevented FGF23 elevations in response to inflammation,but not iron deficiency or phosphate,and administration of LCN2 increased serum FGF23 in healthy and CKd mice by stimulating Fgf23 transcription via activation of cAMP-mediated signaling in bone *** results show that kidney-produced LCN2 is an important mediator of increased FGF23 production by bone in response to inflammation and in ***2 inhibition might represent a potential therapeutic approach to lower FGF23 and improve outcomes in CKd.

关键词： FGF23 kidney inflammation

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Ending Privacy’s Gremlin: Stopping the data-Broker Loophole to the Fourth Amendment’s Search Warrant Requirement

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Journal of Information Security 2024年第4期15卷 589-611页

作者： samantha B. Larkin Shakour Abuzneid department of Cybersecurity Roger Williams University Bristol USA

Advances in technology require upgrades in the law. One such area involves data brokers, which have thus far gone unregulated. data brokers use artificial intelligence to aggregate information into data profiles about individual Americans derived from consumer use of the internet and connected devices. data profiles are then sold for profit. Government investigators use a legal loophole to purchase this data instead of obtaining a search warrant, which the Fourth Amendment would otherwise require. Consumers have lacked a reasonable means to fight or correct the information data brokers collect. Americans may not even be aware of the risks of data aggregation, which upends the test of reasonable expectations used in a search warrant analysis. data aggregation should be controlled and regulated, which is the direction some privacy laws take. Legislatures must step forward to safeguard against shadowy data-profiling practices, whether abroad or at home. In the meantime, courts can modify their search warrant analysis by including data privacy principles.

关键词： Access Control Access Rights Artificial Intelligence Consumer Behavior Consumer Protection Criminal law data Brokers data Handling data Privacy data Processing data Profiling digital Forensics

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