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A Modified Cold Molybdenum Cathode Penning Ion Source

Journal of Physical Science and Application 2013年第4期3卷 229-237页

作者： Adel Gomah Helal Hesham El-Khabeary Tawfik samah Ibrihem radwan Accelerators & Ion Sources Department Basic Nuclear Science Division Nuclear Research Center Atomic Energy AuthorityP.N. 13759 Cairo Egypt

In this paper, design and construction of a modified cold molybdenum cathode Penning ion source was described. It consists of copper cylindrical anode with two cone ends and two movable cold molybdenum cathodes. The two cathodes were placed symmetrically at two ends of the anode. The modifications were decrease the length of the cylindrical anode to 4 cm instead of 6 cm, transform the copper emission electrode shape from plate of 40 mm length, 25 mm width and 2 mm thickness to disc of 20 mm diameter and 2 mm thickness and transform the inner uncovered area of the emission electrode from slit of 30 mm length and 10 mm width to disc of 5 mm diameter. The copper emission electrode was placed in the middle of the cylindrical anode and has aperture in the center of different diameters. Faraday cup was placed at different distances from the emission electrode aperture. The electrical discharge and the output ion beam characteristics of the modified ion source were measured at different pressures using argon gas. It was found that the optimum operating conditions of the modified ion source are; anode-cathode distance equal to 6 mm, emission electrode aperture diameter equal to 2.5 mm and emission electrode aperture, Faraday cup distance equals 3 cm. The effect of axial samarium cobalt permanent magnet of intensity equal to 300 Gauss on the discharge characteristics of the ion source was determined.

关键词： Penning ion source cold molybdenum cathode samarium cobalt permanent magnet.

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The Increased Frequency of Carbapenem Resistant Non Fermenting Gram Negative Pathogens as Causes of Health Care Associated Infections in Adult Cancer Patients

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Journal of Cancer Therapy 2015年第10期6卷 881-888页

作者： Hadir A. El-Mahallawy Rasha M. Abdel Hamid Safaa Shawky Hassan samah radwan Magdy Saber Clinical Pathology Department National Cancer Institute Cairo University Giza Egypt Medical Oncology Department National Cancer Institute Cairo University Giza Egypt

Background and Aim: Multi drug resistant Non fermenting gram negative bacilli (NFGNB) have emerged as a major cause of health-care associated infections especially in immunocompromised hosts. The aim of the study was to investigate the prevalence of NFGNB as a cause of health-care associated infections (HAI) in cancer patients and determine their resistance pattern. Patients and Methods: During the study period, 158 NFGNB isolates were collected. Microscan Walk Away 9 was used for identification and testing for the metallo-β-lactamases (MBLs) was done by Imipenem-EDTA combined disk synergy test (CDST-IPM). Results: NFGNB represented 29.0% of infections caused by gram negative organisms. Carbapenem resistance, the multi-drug resistant (MDR) phenotype, and MBL production were documented in 70%, 63%, and 59% of NFGNB isolates, respectively. MDR-NFGNB rates were significantly higher among hospitalized patients, medical department and those with longer duration of hospital stay (p = 0.034, 0.026, 0.019;respectively) than non MDR-NFGNB. Conclusion: A high level of carbapenem and multi-drug resistance were detected among the non-fermenter pathogens isolated from hospitalized cases and were more frequently encountered in high risk adult cancer patients requiring longer duration of hospitalization. The MDR-NFGNB are constituting important causes of health-care associated infections in cancer patients.

关键词： Multi Drug Resistant Organisms (MDRO) Non-Fermenting Gram Negative Bacilli (NF-GNB) Metallo-β-Lactamases (MBL) Surgical Site Infections (SSI)

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