检索结果-南通市图书馆

Impact of carbimazole combined with vitamin E on testicular injury induced by experimental hyperthyroidism in adult albino rats:oxidative/inflammatory/apoptotic pathways

引用

Asian Journal of Andrology 2024年第4期26卷 396-401页

作者： Ramadan S Hussein moustafa m Eyada Rashad m mostafa samah m elaidy Shereen H Elsayed Hany m Saad Department of Dermatology College of Medicine Prince Sattam Bin Abdulaziz UniversityAl-Kharj 16242Saudi Arabia Department of Dermatology Andrology and STDsAssiut Police HospitalAssiut 71525Egypt Department of Dermatology Venereology and AndrologyFaculty of MedicineSuez Canal UniversityIsmailia 41522Egypt Department of Andrology and Sexology Faculty of MedicineSuez Canal UniversityIsmailia 41511Egypt Department of Clinical Pharmacology Faculty of MedicineSuez Canal UniversityIsmailia 41511Egypt Department of Rehabilitation Sciences Faculty of Health and Rehabilitation SciencesPrincess Nourah bint Abdulrahman UniversityRiyadh 12271Saudi Arabia.

Thyroid hormones play essential roles in spermatogenesis,but their effects on infertile males remain poorly *** study aimed to evaluate the impact of combining carbimazole(CBZ)with vitamin E(VE)on testicular injury induced by experimental hyperthyroidism in adult albino rats,focusing on oxidative,inflammatory,and apoptotic *** this experimental study,64 adult male albino Wistar rats were divided into eight groups:Group I(control-untreated),Group II(CBZ-control),Group III(VE-control),Group IV(CBZ+VE-control),Group V(levothyroxine-induced testicular injury),Group VI(levothyroxine+CBZ-treated),Group VII(levothyroxine+VE-treated),and Group VIII(levothyroxine+CBZ+VE-treated).The study was conducted in the Faculty of medicine,Suez Canal University(Ismailia,Egypt).After cervical decapitation,both testes and epididymis were examined histopathologically and *** differences were observed among groups concerning malondialdehyde(mDA),glutathione(GSH),superoxide dismutase(SOD),and catalase(CAT;all Pmerase chain reaction analysis showed significant differences in tumor necrosis factor-α(TNF-α),interleukin-10(IL-10),Bcl-2-associated X protein(BAX),B-cell lymphoma 2 protein(Bcl2),p53,Caspase-3,Caspase-8,Caspase-9,and nuclear factor-kappa B(NF-κB)mRNA levels(all Pminiferous tubules and ***,the Group VIII showed improved spermatogenesis and a decrease in testicular side *** addition of VE to the treatment of hyperthyroid rats with CBZ reduced testicular side effects and seminiferous tubular affection when potentially improving *** research is needed to elucidate the underlying mechanisms fully.

关键词： antithyroid drugs testicular injury thyroid gland vitamin E

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

moringa oleifera Lam. leaf extract mitigates carbon tetrachloride-mediated hepatic inflammation and apoptosis via targeting oxidative stress and toll-like receptor 4/nuclear factor kappa B pathway in mice

引用

Food Science and Human Wellness 2021年第3期10卷 383-391页

作者： samah m.Fathy mohammed S.m.mohammed Zoology Department Faculty of ScienceFayoum UniversityFayoumEgypt

Carbon tetrachloride(CCl4)is a hepatotoxin that triggers liver *** study aimed to evaluate the protective effect of phytochemicals detected in moringa oleifera *** extract(mOLE)on CCl4-induced hepatotoxicity in ***,total phenolics,and total fl avonoids were detected in *** markedly decreased the elevation of serum alanine aminotransferase(ALT)and aspartate aminotransferase(AST)in consistence with the ameliorating effect on CCl4-induced histopathological ***,mOLE significantly alleviated the decrease in the antioxidant defense mechanism induced by *** suppressing effect of mOLE on the boosted inflammatory pathway triggered by CCl4 was detected by measuring the protein levels of nuclear factor kappa-light-chain-enhancer of activated B-cells(NF-κB-p65),toll-like receptor 4(TLR4),tumor necrosis factor-α(TNF-α),interleukin(IL)-6,IL-1β,and IL-8 as well as the relative expressions of nuclear factor kappa B(NF-κB),TNF-α,IL-1β,and TLR4 *** and genotoxicity induced by CCl4 were signifi cantly alleviated by *** co-administration modulated TLR4/NF-κB pathway as presented by the suppressed gene expression of TLR4 and NF-κB as well as by the reduced protein expression of TLR4 and NF-κ*** conclusion,mOLE has a multifarious protective role against hepatotoxicity through control of oxidative stress and modulation of TLR4/NF-κB.

关键词： CCl4 Infl ammation moringa oleifera Lam. Oxidative stress TLR4/NF-κB

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Phase modification and dielectric properties of a cullet–paper ash–kaolin clay-based ceramic

引用

International Journal of minerals,metallurgy and materials 2018年第3期25卷 350-356页

作者： K.A.samah m.R.Sahar m.Yusop m.F.Omar Advance Optical material Research Group Department of Physics Faculty of Science Universiti Teknologi Malaysia

Novel ceramics from waste material made of(x) paper ash–(80-x) cullet–20 kaolin clay(10 wt% ≤ x ≤ 30 wt%) were successfully synthesized using a conventional solid-state reaction technique. Energy-dispersive X-ray analysis confirmed the presence of Si, Ca, Al, and Fe in the waste material for preparing these ceramics. The influence of the cullet content on the phase structures and the dielectric properties of these ceramics were systematically investigated. The impedance spectra were verified in the range from 1 Hz to 10 mHz at room temperature. The phase of the ceramics was found to primarily consist of wollastonite(CaSiO_3), along with minor phases of γ-dicalcium silicate(Ca_2SiO_4) and quartz(SiO_2). The sample with a cullet content of 55 wt% possessed the optimum wollastonite structure and exhibited good dielectric properties. An increase of the cullet content beyond 55 wt% resulted in a structural change from wollastonite to dicalcium silicate, a decrease in dielectric constant, and an increase in dielectric loss. All experimental results suggested that these novel ceramics from waste are applicable for electronic devices.

关键词： ceramics cullet glass paper ash wollastonite structural properties dielectric properties

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A New Reliable System For managing Virtual Cloud Network

引用

Computers, materials & Continua 2022年第12期73卷 5863-5885页

作者： samah Alshathri Fatma m.Talaat Aida A.Nasr Department of Information Technology College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh 11671Saudi Arabia Faculty of Artificial Intelligence Kafrelsheikh UniversityKafrelsheikhEgypt Faculity of Computers and Informatics Tanta UniversityTantaEgypt

Virtual cloud network(VCN)usage is popular today among large and small organizations due to its safety and ***,it makes all resources in the company work as one *** also facilitates sharing of files and applications without ***,cloud providers face many issues in managing the VCN on cloud computing including these issues:Power consumption,network failures,and data *** issues often occur due to overloaded and unbalanced load *** this paper,we propose a new automatic system to manage VCN for executing the *** new system calledmulti-User Hybrid Scheduling(mUSH)can solve running issues and save power during workflow *** consists of three phases:Initialization,virtual machine allocation,and task scheduling *** mUSH system focuses on the execution of the workflow with deadline ***,it considers the utilization of virtual *** new system can save makespan and increase the throughput of the execution operation.

关键词： Virtual network scheduling reliability Vm allocation cloud computing

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Latency-Aware Dynamic Second Offloading Service in SDN-Based Fog Architecture

引用

Computers, materials & Continua 2023年第4期75卷 1501-1526页

作者： samah Ibrahim AlShathri Dina S.m.Hassan Samia Allaoua Chelloug Information Technology Department College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityRiyadh84428Saudi Arabia

Task offloading is a key strategy in Fog Computing (FC). Thedefinition of resource-constrained devices no longer applies to sensors andInternet of Things (IoT) embedded system devices alone. Smart and mobileunits can also be viewed as resource-constrained devices if the power, cloudapplications, and data cloud are included in the set of required resources. Ina cloud-fog-based architecture, a task instance running on an end device mayneed to be offloaded to a fog node to complete its execution. However, ina busy network, a second offloading decision is required when the fog nodebecomes overloaded. The possibility of offloading a task, for the second time,to a fog or a cloud node depends to a great extent on task importance, latencyconstraints, and required resources. This paper presents a dynamic service thatdetermines which tasks can endure a second offloading. The task type, latencyconstraints, and amount of required resources are used to select the offloadingdestination node. This study proposes three heuristic offloading *** algorithm targets a specific task type. An overloaded fog node can onlyissue one offloading request to execute one of these algorithms accordingto the task offloading priority. Offloading requests are sent to a SoftwareDefined Networking (SDN) controller. The fog node and controller determinethe number of offloaded tasks. Simulation results show that the average timerequired to select offloading nodes was improved by 33% when compared tothe dynamic fog-to-fog offloading algorithm. The distribution of workloadconverges to a uniform distribution when offloading latency-sensitive nonurgenttasks. The lowest offloading priority is assigned to latency-sensitivetasks with hard deadlines. At least 70% of these tasks are offloaded to fognodes that are one to three hops away from the overloaded node.

关键词： Fog computing offloading algorithm latency-aware software defined networking SDN

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Fuzzy Control Based Resource Scheduling in IoT Edge Computing

引用

Computers, materials & Continua 2022年第6期71卷 4855-4870页

作者： samah Alhazmi Kailash Kumar Soha Alhelaly College of Computing and Informatics Saudi Electronic UniversityRiyadhKingdom of Saudi Arabia

Edge Computing is a new technology in Internet of Things(IoT)paradigm that allows sensitive data to be sent to disperse devices quickly and without *** is identical to Fog,except its positioning in the end devices is much nearer to end-users,making it process and respond to clients in less ***,it aids sensor networks,real-time streaming apps,and the IoT,all of which require high-speed and dependable internet *** such an IoT system,Resource Scheduling Process(RSP)seems to be one of the most important *** paper presents a RSP for Edge Computing(EC).The resource characteristics are first standardized and ***,for task scheduling,a Fuzzy Control based Edge Resource Scheduling(FCERS)is *** results demonstrate that this technique enhances resource scheduling efficiency in EC and Quality of Service(QoS).The experimental study revealed that the suggested FCERS method in this work converges quicker than the other *** method reduces the total computing cost,execution time,and energy consumption on average compared to the *** ES allocates higher processing resources to each user in case of limited availability of mDs;this results in improved task execution time and a reduced total task computation ***,the proposed FCERS m 1m may more efficiently fetch user requests to suitable resource categories,increasing user requirements.

关键词： IoT edge computing resource scheduling task scheduling fuzzy control

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of restoration technique on resistance to fracture of endodontically treated anterior teeth with flared root canals

引用

The Journal of Biomedical Research 2019年第2期33卷 131-138页

作者： Sary S Borzangy samah m Saker Walid A Al-Zordk Department of Substitutive Dental Sciences College of Dentistry Taibah University Department of Fixed Prosthodontics Faculty of Dentistry Mansoura University

This study was designed to compare the impact of post and core systems on resistance to fracture of endodontically treated anterior teeth with flared root canals and to assess their fracture pattern. Sixty central incisors were cut horizontally 2 mm coronal to the cementoenamel junction(CEJ). After root canal therapy, teeth were assigned into 6 groups(n = 10 each) based on a post system and used as follows: Group C, non-flared root received size #1 glass fiber posts(Control); Group AP, flared root restored with anatomical post; Group RC, flared root restored with size #1 fiber post and cemented with thick layer of resin cement; Group CR, flared root restored with size #1 and reinforced with composite resin; Group Cm, cast post-core; Group CP, CAD/CAm polymer-infiltrated ceramic post and *** post cementation, core build-up and crown insertion, the specimens were thermo-cycled up to 10,000 cycles(5 C/55 C; 30 seconds dwell time, 6 seconds transition time) and then statically loaded at 1 mm/minute crosshead speed using a universal testing machine. One-way ANOVA and Tukey HSD post hoc test(α= 0.05) were used for data analysis. Group C recorded significantly higher resistance to fracture values [(826.9±39.1) N] followed by group CP [(793.8±55.6) N] while group RC yielded the lowest fracture resistance values [(586.7±51.4) N]. The resistance to fracture of wide root canals can be enhanced by using one-piece CAm/CAm post and core as an alternative to the use of either glass fiber post, relined with composite resin increasing the thickness of luting cement or the use of cast post and core system. However, this was an in vitro investigation and further in vivo studies are necessary.

关键词： anatomical post customized post endodontically treated teeth flared root canal

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The protection of Thymus vulgaris leaves alcoholic extract against hepatotoxicity of alcohol in rats

引用

Asian Pacific Journal of Tropical medicine 2017年第4期10卷 341-351页

作者： samah A.El-Newary Nermeen m.Shaffie E.A.Omer medicinal and Aromatic Plants Research Department Pharmaceutical Industries Research DivisionNational Research Center Pathology Department Medical Researches DivisionNational Research CentreGiza Egypt

Objective:This study was performed to investigate the protective effect of Thymus vulgaris(***) leaves 70%alcoholic extract against alcohol-mediate hepatotoxicity ***:The protective effect of extract was investigated at dose of 500 mg/kg/day orally against alcohol-mediate hepatotoxicity using adult male Wister albino rats during 21 *** effect of *** extract was evaluated comparing with silymarin standard drug al recommended dose(25 mg/kg/day) orally for 21 ***:Alcohol-mediate hepatotoxicity rats(alcohol-control) showed hepatocytes distortion represented as marked increment on liver biomarkers;alkaline phosphatase(ALP),aspartate transaminase(AST) and alanine transaminase(ALT) activities,as well as pronounced reduction on total protein and its fractions albumin and globulin corresponding to normal *** to oxidative stress status as depletion on glutathione concentration,catalase(CAT),superoxide dismutase(SOD),glutathione reductase(GR),glutathione-S-transferase(GST) and glutathione peroxidase(GPx)activities,concurrence with augmentation oxidative stress parameters;malondyaldchydc(mDA) and hydrogen peroxide(H_2O_2) concentrations comparing to normal *** administration elevated total cholesterol(TC),low density lipoprotein cholesterol(LDL-C) and high density lipoprotein cholesterol(HDL-C) comparing to normal ***-administration *** extract with alcohol showed protective effect on hepatocytes manifested as minimizing on *** and ALT activities and increment on total protein,albumin and globulin production compared to *** enzymes activities;***,GST and GPx were significantly magnified,while mDA and H_2O_2 concentration were lessened corresponding to ***,lipid profile was markedly improved and risk ratio was lowered compared to *** results were confirmed by normalization of degenerated and fibrotic liver tissue as of alcohol-cont

关键词： Thymus vulgaris Alcohol-mediate hepatotoxicity Polyphenols Flavonoids Antioxidants enzymes activities Oxidative stress Histopathology

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Leucine-rich repeat-containing G protein-coupled receptor 5 marks different cancer stem cell compartments in human Caco-2 and LoVo colon cancer lines

引用

World Journal of Gastroenterology 2021年第15期27卷 1578-1594页

作者： samah Abdulaali Alharbi Dmitry A Ovchinnikov Ernst Wolvetang Physiology Department College of MedicineUmm Al-Qura UniversityMakkah 24231Saudi Arabia Department of Stem Cell Engineering Group Australian Institute for Bioengineering and NanotechnologyThe University of QueenslandBrisbane 4072QLDAustralia Australian Institute for Bioengineering and Nanotechnology The University of QueenslandBrisbane 4072QLDAustralia

BACKGROUND Colon cancer cell lines are widely used for research and for the screening of drugs that specifically target the stem cell compartment of colon *** was reported that colon cancer carcinoma specimens contain a subset of leucine-rich repeatcontaining G protein-coupled receptor 5(LGR5)-expressing stem cells,these socalled“tumour-initiating”cells,reminiscent in their properties of the normal intestinal stem cells(ISCs),may explain the apparent heterogeneity of colon cancer cell ***,colon cancer is initiated by aberrant Wnt signaling in ISCs known to express high levels of ***,in vivo reports demonstrate the clonal expansion of intestinal adenomas from a single LGR5-expressing *** To investigate whether colon cancer cell lines contain cancer stem cells and to characterize these putative cancer stem *** A portable fluorescent reporter construct based on a conserved fragment of the LGR5 promoter was used to isolate the cell compartments expressing different levels of LGR5 in two widely used colon cancer cell lines(Caco-2 and LoVo).These cells were then characterized according to their proliferation capacity,gene expression signatures of ISC markers,and their tumorigenic properties in vivo and in *** The data revealed that the LGR5 reporter can be used to identify and isolate a classical intestinal crypt stem cell-like population from the Caco-2,but not from the LoVo,cell lines,in which the cancer stem cell population is more akin to B lymphoma moloney murine leukemia virus insertion region 1 homolog(+4 crypt)stem *** sub-population within Caco-2 cells exhibits an intestinal cancer stem cell gene expression signature and can both self-renew and generate differentiated LGR5 negative *** data also show that cells expressing high levels of LGR5/enhanced yellow fluorescent protein(EYFP)from this cell line exhibit tumorigenic-like properties in vivo and in *** contrast,cell compartments of LoVo th

关键词： Colorectal cancer Colon cancer cell lines Intestinal stem cell Cancer stem cell Leucine-rich repeat-containing G protein-coupled receptor 5 Heterogenicity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rainfall prediction by using ANFIS times series technique in South Tangerang, Indonesia

引用

Geodesy and Geodynamics 2020年第6期11卷 411-417页

作者： Wayan Suparta Azizan Abu samah Institute of Ocean and Earth Sciences(IOES) University of Malaya50603Kuala LumpurMalaysia Department of Electrical Engineering Institut Teknologi Nasional YogyakartaJl.BabarsariCaturtunggalDepokSlemanYogyakarta55281Indonesia

Excessive rainfall is one of the triggers for the flooding phenomenon,especially in the tropics with flat or concave *** critical points in the South Tangerang region,which are currently one of the most rapidly developing cities,cannot be ignored from the flooding *** cause disturbing human activities,loss of life and property,and in turn affect the economic stretch in an *** paper aimed to predict rainfall by exploring the application of artificial intelligence techniques such as ANFIS(Adaptive Neuro Fuzzy Inference System).The proposed technique combines neural network learning abilities with transparent linguistic representations of fuzzy *** ANFIS model with various input structures and membership functions was built,trained,and tested to evaluate the capability of a *** of six-year rainfall data on a monthly basis in South Tangerang City,Banten found that rainfall prediction based on ANFIS time series is promising where 80%of data testing is well predicted.

关键词： ANFIS Time series Rainfall South Tangerang

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：