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Journal of Materials Science & Technology 2006年第4期22卷 500-510页

作者： Minh-Quy LE Seock-sam kim Department of Mechanics of Materials and Structures Faculty of Mechanical EngineeringHanoi University of TechnologyDai Co Viet RoadHanoiVietnam School of Mechanical Engineering Kyungpook National UniversityDaegu 701-702Korea

Spherical indentation of ceramic coatings with metallic interlayer was performed by means of axisymmetric finite element analysis （FEA）. Two typical ceramic coatings with relatively high and low elastic modulus deposited on aluminum alloy and carbon steel were considered. Various combinations of indenter radius-coating thickness ratios and interlayer thickness-coating thickness ratios were used in the modeling. The effects of the interlayer, the coating and the substrate on the indentation behavior, such as the radial stress distribution along the coating surface as well as the coating interface, and the plastic deformation zone evolution in the substrate were investigated in connection with the above mentioned ratios. The coating cracking dominant modes were also discussed within the context of the peak tensile stresses on the coating surface and on the coating interface.

关键词： Finite element analysis Ceramic coatings Indentation Interlayer

Element Analysis of Instrumented Sharp Indentations into Pressure-sensitive Materials

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Journal of Materials Science & Technology 2007年第2期23卷 277-282页

作者： Minh-Quy LE Seock-sam kim Department of Mechanics of Materials & Structures Faculty of Mechanical EngineeringHanoi University of TechnologyDai Co Viet RoadHanoi Vietnam School of Mechanical Engineering Kyungpook National UniversityDaegu 702-701South Korea

Finite element analysis was carried out to investigate the conical indentation response of elastic-plastic solids within the framework of the hydrostatic pressure dependence and the power law strain hardening. A large number of 40 difierent combinations of elasto-plastic properties with n ranging from 0 to 0.5 and σy/E ranging from 0.0014 to 0.03 were used in the computations. The loading curvature C and the average contact pressure Pave were considered within the concept of representative strains and the dimensional *** functions associated with these two parameters were formulated for each studied value of the pressure sensitivity. The results for pressure sensitive materials lie between those for Von Mises materials and the elastic model.

关键词： Finite element analysis Indentation Mechanical Properties Pressure-sensitive materials

Element Analysis of Ceramic Coatings under Spherical Indentation with Metallic Interlayer: PartⅡRing Crack

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Journal of Materials Science & Technology 2006年第5期22卷 594-598页

作者： Minh-Quy LE Seock-sam kim Department of Mechanics of Materials & Structures Faculty of Mechanical Engineering Hanoi University of TechnologyDai Co Viet RoadHanoiVietnam School of Mechanical Engineering Kyungpook National University Daegu 701-702Korea

Spherical indentation of ceramic coatings with metallic interlayer was performed by means of axisymmetric finite element analysis （FEA）. Two typical ceramic coatings with relatively high and low elastic modulus deposited on aluminum alloy and carbon steel were considered. The fracture mechanics of the ceramic coatings mechanisms due to occurrence of surface ring cracks extending traverse the coating thickness under spherical indentation are investigated within the framework of linear fracture mechanics. The J-integral associated to such cracks was computed. The evolution of J-integral vs the crack length and the indentation depth was studied. The effects of the interlayer, the coating and the substrate on the J-integral evolution were discussed. The results show that a suitable metallic interlayer can improve the fracture resistance of the coating systems under the same indentation conditions through reducing the J-integral.

关键词： Finite element analysis Ceramic coatings Indentation Interlayer Crack

Sliding Wear Behavior of Plasma Sprayed Zirconia Coating on Cast Aluminum against Silicon Carbide Ceramic

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Journal of Materials Science & Technology 2005年第5期21卷 666-670页

作者： Thuong-Hien LE Young-Hun CHAE Seock-sam kim School of Mechanical Engineering Graduate School Kyungpook National University Daegu 702-701 KoreaEngineering Tribology Research Institute Kyungpook National University Daegu 702-701 KoreaSchool of Mechanical Engineering Kyungpook National University Daegu 702-701 Korea

The sliding wear behaviors of ZrO2-22 wt pct MgO （MZ） and ZrO2-8 wt pct Y2O3（YZ） coatings deposited on a cast aluminum alloy with bond layer （NiCrCoAlY） by plasma spray were investigated under dry test conditions at room temperature. Under all load conditions, the wear mechanisms of the MZ and YZ coatings were almost the same. The material transfer and pullout were involved in the wear process of the studied coatings under the test conditions. The wear rate of the MZ coating was less than that of the YZ coating. While increasing the normal load, the wear rates of the MZ and YZ coatings increased. SEM was used to examine the worn surfaces and to elucidate likely wear mechanisms. Energy dispersive X-ray spectroscopy （EDX） analysis of the worn surfaces indicated that material transfer occurred in the direction from the SiC ball to the disk. Fracture toughness had a significant influence on the wear performance of the coatings. It was suggested that the material transfer played an important role in the wear behavior.

关键词： Plasma spray Zirconia coating Wear mechanism Fracture toughness

Early prediction of myocardial viability after acute myocardial infarction by two-dimensional speckle tracking imaging

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Journal of Geriatric Cardiology 2015年第5期12卷 474-481页

作者： Jong Shin Woo Tae-Kyung Yu Woo-Shik kim Kwon sam kim Weon kim Division of Cardiology Department of lnternal Medicine Kyung Hee University Hospital Kyung Hee University Seoul South Korea

BackgroundIdentifying 心肌的坏死和在尖锐心肌的梗塞(AMI ) 的心肌的生存能力的度的 transmural 程度临床上是重要的。这研究的目的是用二维的点缀追踪估计心肌的生存能力在有 ***2D-STI 的病人的成像( 2D-STI )与 AMI 在 30 个病人... 详细信息

BackgroundIdentifying 心肌的坏死和在尖锐心肌的梗塞(AMI ) 的心肌的生存能力的度的 transmural 程度临床上是重要的。这研究的目的是用二维的点缀追踪估计心肌的生存能力在有 ***2D-STI 的病人的成像( 2D-STI )与 AMI 在 30 个病人在主要经皮的冠的干预(一种总线标准)以后在起始的表示，三天，和六个月被执行，谁有左前面的下降冠的动脉(男孩)犯人损害。另外，有最小的 stenotic 损害的 20 个病人(<；30% 狭窄) 也在控制组在冠的 angiography 上被包括。在六月 dobutamine， echocardiography 在 LAD 领土的七个片断为生存能力评价被执行。根据墙运动反常的恢复，片断作为可行被分类或 131 个片断全部的 *** 是可行的，并且 44 是不能生存的。Multivariate 分析在山峰揭示了可行、不能生存的片断之间的重要差别收缩紧张，山峰在起始的表示的收缩紧张率，和山峰在主要一种总线标准以后的收缩紧张率三天。在这些之中，起始的山峰收缩紧张率为心肌的生存能力有最高预兆的价值(危险比率：31.22， P <；0.01 ).Conclusions2D-STI 为估计收缩紧张率可能是的心肌的生存能力，和山峰是可行的在有 AMI 的病人的心肌的生存能力的最可靠的预言者。

关键词：急性心肌梗死早期预测成像技术追踪斑点二维冠状动脉造影峰值应变

Aortic arch calcification on chest X-ray combined with coronary calcium score show additional benefit for diagnosis and outcome in patients with angina

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Journal of Geriatric Cardiology 2016年第3期13卷 218-225页

作者： Jong Shin Woo Weon kim Se Hwan Kwon Hyo Chul Youn Hyun Soo kim Jin Bae kim Soo Joong kim Woo-Shik kim Kwon sam kim Cardiovascular Division Department of Internal Medicine Kyung Hee University Hospital Kyung Hee University Seoul South Korea Department of Radiology Kyung Hee University Hospital Kyung Hee University Seoul South Korea Department of Thoracic and Cardiovascular Surgery Kyung Hee University Hospital Kyung Hee University Seoul South Korea

BackgroundThe 冠的动脉钙(CAC ) 和大动脉的拱门石灰化(AoAC ) 个别地与心血管的疾病和结果被联系。这研究调查了与经历了胸X光检查的 2018 个稳定的咽峡炎病人全部的 *** 在病人为心血管的诊断和结果与 CAC 相结合的 AoAC 的预兆的价... 详细信息

BackgroundThe 冠的动脉钙(CAC ) 和大动脉的拱门石灰化(AoAC ) 个别地与心血管的疾病和结果被联系。这研究调查了与经历了胸X光检查的 2018 个稳定的咽峡炎病人全部的 *** 在病人为心血管的诊断和结果与 CAC 相结合的 AoAC 的预兆的价值，心脏的多察觉者计算了断层摄影术被跟随在上面四年估计不利事件，它作为心脏的死亡被分类，击，心肌的梗塞，或重复 revascularization 。胸 X 光检查上的 AoAC 的程度从 0 ～ 3 .ResultsDuring 在规模上被分级后续的四年， 620 个病人被冠的 stenting 对待并且 153 (7%) 不利事件发生了。AoAC 的一个更高的等级与一个更高的 CAC 分数被联系。考克斯回归证明 CAC 分数，然而并非 AoAC，与不利事件被联系。在有 CAC 的病人获得 <；400， AoAC 显示出添加剂在检测重要冠的动脉疾病(CAD ) 的预兆的价值。一如果 AoAC 在有类似的 CAC *** AoAC 的病人是在场的，不利事件的风险的渐渐的增加被注意强烈不管年龄或性与 CAC 分数被相关， CAD 的小心的评估将在常规胸 X 光上与 AoAC 在病人被要求。

关键词：冠状动脉疾病心绞痛患者钙化预后诊断冠心病心血管疾病

Inhibitory effect of Jeju endemic seaweeds on the production of pro-inflammatory mediators in mouse macrophage cell line RAW 264.7

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2010年第5期11卷 315-322页

作者： Eun-Jin YANG Ji-Young MOON Min-Jin kim Dong sam kim Chan-Shick kim Wook Jae LEE Nam Ho LEE Chang-Gu HYUN Jeju Biodiversity Research Institute(JBRI) Jeju High-Tech Development Institute(HiDI) Jeju 699-943Korea Jeju Seaweed Industry Development Agency Cheju National UniversityJeju 690-756Korea Faculty of Biotechnology Cheju National UniversityJeju 690-756Korea Department of Chemistry Cheju National UniversityJeju 690-756Korea

Seaweed has been used in traditional cosmetics and as a herbal medicine in treatments for cough,boils,goiters,stomach ailments,and urinary diseases,and for reducing the incidence of tumors,ulcers,and *** the fact that seaweeds are frequently used in the practice of human health,little is known about the role of seaweed in the context of *** study aimed to investigate the influence of Jeju endemic seaweed on a mouse macrophage cell line(RAW 264.7) under the stimulation of lipopolysaccharide(LPS).Ethyl acetate extracts obtained from 14 different kinds of Jeju seaweeds were screened for inhibitory effects on pro-inflammatory *** results revealed that extracts from five seaweeds,Laurencia okamurae,Grateloupia elliptica,Sargassum thun-bergii,Gloiopeltis furcata,and Hizikia fusiformis,were potent inhibitors of the production of pro-inflammatory mediators such as nitric oxide(NO),prostaglandin E2(PGE2),interleukin-6(IL-6),and tumor necrosis factor-α(TNF-α).Based on these results,the anti-inflammatory effects and low cell toxicity of these seaweed extracts suggest potential thera-peutic applications in the regulation of the inflammatory response.

关键词： Nitric oxide Interleukin-6(IL-6) Prostaglandin E2(PGE2) Tumor necrosis factor-α(TNF-α) Seaweeds Pro-inflammatory mediators

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养育负担沉重韩国生育率全球垫底

商业周刊（中文版） 2022年第16期 24-26页

作者： sam kim 邵璐宁(译) 不详

韩国民众的生育意愿创历史新低,促使政府采取新一轮行动,以免发生可能给国家经济增长和社会福利体系带来压力的人口危机。去年韩国的生育率刷新全球最低纪录。其他一些预测称,到本世纪末,韩国人口将减少一半。就连埃隆·马斯克也发表了... 详细信息

韩国民众的生育意愿创历史新低,促使政府采取新一轮行动,以免发生可能给国家经济增长和社会福利体系带来压力的人口危机。去年韩国的生育率刷新全球最低纪录。其他一些预测称,到本世纪末,韩国人口将减少一半。就连埃隆·马斯克也发表了意见,称韩国的情况“很可怕”。

关键词：人口危机社会福利体系生育率生育意愿韩国

Effects of Scutellaria baicalensis on neurogenesis in the hippocampal dentate gyrus and on spatial memory of adult rats

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Neural Regeneration Research 2011年第27期6卷 2085-2093页

作者： Sun-Hwa Lee Byung-soo Ahn Bong-soo Lim Seong-Kyu kim sam-Ki kim Dae-Il Lee Sung-Rae Cho Deok-Gon kim Jae-Bok Han Byung-Il Min Department of East-West Medicine Graduate SchoolKyunghee University Department & Research Institute of Rehabilitation Medicine Yonsei University Department of Oriental Pediatrics Kyunghee Medical CenterKyunghee University Department of Physiology College of MedicineKyunghee University

We investigated the effects of ethanol extracted Scutellaria baicalensis（EESB） on spatial memory function and neurogenesis in the hippocampal dentate *** Sprague-Dawley rats were orally administered 50,100,or 200 mg/kg of EESB for 6 successive *** radial-arm maze test showed that 200 mg/kg of EESB improved the spatial memory of adult *** microscopy results showed that 100 mg/kg of EESB increased the number of bromodeoxyuridine（BrdU）-and neuron-specific nuclear protein-positive cells in the granular cell layer,and that 100 and 200 mg/kg of EESB increased the number of BrdU-/neuron-specific nuclear protein-positive cells in the sub-granular zone.200 mg/kg of EESB increased the number of BrdU-/glial fibrillary acid protein-positive cells in the subgranular *** findings indicate that EESB can effectively promote neurogenesis in the hippocampal dentate gyrus and improve spatial memory function.

关键词： Scutellaria baicalensis neurogenesis dentate gyrus hippocampus bromodeoxyuridine neuron-specific nuclear protein glial fibrillary acidic protein neural regeneration

An insert in the Hpy region of hscp in Hefiothis virescens （Lepidoptera： Noctuidae） reveals a possible CORE-SINE of insects

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Insect Science 2009年第3期16卷 219-226页

作者： Sujin Park Thomas M. Brown sam-Kyu kim Chunkeun Lim Jang Hyun Hur Yong Chul Park Saeyoull Cho Life Science Institute University of Michigan Ann Arbor M148109 USA Genectar Corn LLC 539 Kafispell Ave. Whitefish MT 59937-2743 USA Division of Biological Environment College of Agriculture and Life Science Kangwon National University Chuncheon 200-701Korea Department of Appfied Biology Division of Bio-resource of Technology College of Agriculture and Life Science Kangwon National University Chuncheon 200-701 Korea Department of Plant Biotechnology Program Division of Biotechnology School of BiotechnologyInstitute of Bioscience and Biotechnology Kangwon National University Chuncheon 200-701 Korea

A new putative transposon was identified in the tobacco budworm, Helio- this virescens. This transposon was characterized as a full length CORE-SINE （65 bp of ＂CORE＂ core specific nucleotide short interspersed elements） that resembled sequences from three other lepidopterans and humans. In particular, the A-box and B-box regions of this sequence most closely conformed to the signature of CORE-SINEs from widely divergent species. This CORE-SINE was present as a polymorphism in a hypervariable region of the gene hscp, which is the target of pyrethroid insecticides and other xenobiotics in the nerve axon. We described this new putative transposon as Noct-1 due to its presence in a noctuid moth. This is the first description of a full-length CORE-SINE with the A-box, B-box, target site duplication, and candidate core domain from an insect.

关键词： A-box B-box CORE-SINE Heliothis virescens Noct-1 target site duplication