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Study of the Impact of the Patient Rhythm during Cryoballoon Ablation on the Acute Biophysical Parameters

World Journal of Cardiovascular Diseases 2022年第1期12卷 65-76页

作者： Mohamed Sanhoury Gaetano Fassini salvatore pala Massimo Moltrasio Fabrizio Tundo Stefania Riva Antonio Dello Russo Michela Casella Claudio Tondo Cardiac Arrhythmia Research Centre Department of Cardiovascular Sciences University of Milan Centro Cardiologico Monzino IRCCS Milan Italy Electrophysiology Unit Department of Cardiology and Angiology University of Alexandria Alexandria Egypt

Background: Pulmonary vein isolation by means of cryoballoon is a well-established way of treatment of atrial fibrillation. The aim of the study was to compare the acute cryoballoon biophysical parameters attained during energy applications to the individual pulmonary vein during sinus rhythm versus atrial fibrillation. Methods: 100 Patients who underwent their first-time PVI using second-generation cryoballoon for symptomatic and drug-refractory AF, between the beginning of March to end of August 2016, were initially screened. 61 patients with paroxysmal AF were included in the present study. 39 patients with persistent AF were excluded. No pre-procedural anatomical imaging was reported. Results: A total of 61 patients (male 80%, age 59.3 ± 13.4 years) were included in the present analysis.

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Electrical storm: A clinical and electrophysiological overview

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World Journal of Cardiology 2015年第9期7卷 555-561页

作者： Sergio Conti salvatore pala Viviana Biagioli Giuseppe Del Giorno Martina Zucchetti Eleonora Russo Vittoria Marino Antonio Dello Russo Michela Casella Francesca Pizzamiglio Valentina Catto Claudio Tondo Corrado Carbucicchio Cardiac Arrhythmia Research Centre Centro Cardiologico Monzino IRCCS

Electrical storm(ES) is a clinical condition characterized by three or more ventricular arrhythmia episodes leading to appropriate implantable cardioverterdefibrillator(ICD) therapies in a 24 h period. Mostly, arrhythmias responsible of ES are multiple morphologies of monomorphic ventricular tachycardia(VT), but polymorphic VT and ventricular fibrillation can also result in ES. Clinical presentation is very dramatic in most cases, strictly related to the cardiac disease that may worsen electrical and hemodynamic decompensation. Therefore ES management is challenging in the majority of cases and a high mortality is the rule both in the acute and in the long-term phases. Different underlying cardiomyopathies provide significant clues into the mechanism of ES, which can arise in the setting of structural arrhythmogenic cardiomyopathies or rarely in patients with inherited arrhythmic syndrome, impacting on pharmacological treatment, on ICD programming, and on the opportunity to apply strategies of catheter ablation. This latter has become a pivotal form of treatment due to its high efficacy in modifying the arrhythmogenic substrate and in achieving rhythm stability, aiming at reducing recurrences of ventricular arrhythmia and at improving overall survival. In this review, the most relevant epidemiological and clinical aspects of ES, with regard to the acute and long-term follow-up implications, were evaluated, focusing on these novel therapeutic strategies of treatment.

关键词： Electrical storm Ventricular tachycardia/ fibrilla

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