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Material characterization and inter/intra-particle validation for DEM simulation of urea coating process

Particuology 2024年第5期88卷 32-48页

作者： salma A.Nouh KuZilati KuShaari Lau Kok Keong Shafirah Samsuri Chemical Engineering Department Universiti Teknologi PETRONAS32610 Seri IskandarPerak Darul RidzuanMalaysia

Particle coating is a common operation in the controlled-release fertilizer (CRF) industry,where a coating layer is appliedto the urea cores.A discrete element method (DEM) computer simulation was applied to model the coating process for the urea granules using measured model *** accuracy of DEM input parameters for the coating material properties and the physical and mechanical characterizations of urea granules are crucial to the study of particle coating ***,to enhance the simulation accuracy,information on the material properties (urea granules) is *** this study,the elasticity parameters,shear modulus ,coefficient of restitution (CoR),and coefficient of rolling and static friction (CoRF) and (CoSF) of urea granules are estimated experimentally in addition to the physical *** sensitivity of the angle of repose of the urea bed was investigated at different coefficients of *** to the obtained experimental value of the angle of repose,values of 0.2 and 0.3 for CoRF and CoSF,respectively,were adjusted to obtain consistent urea granules’ motion for simulation and the ***,the spray droplet sizes and velocity distributions were estimated using the video-imaging process *** on this experimental characterization,elasticity parameters and spray properties were integrated into DEM simulation software as input data to perform numerical analysis of the coating process to compare simulation and experimental results,which show uniformity at three different pan speeds with a maximum deviation of 0.033 at 5 ***,consistency between DEM and experiment results was achieved in terms of average coating thickness (μm) of the selected samples and average intra-particle thickness variation ( CoV intra ).These results revealed that the coating film thickness is proportional to the rotation speed for the experiment and *** enhance the inter-particle coating uniformity,the effects of the

关键词： Contact model Discrete element method Urea fertilizer Coating process

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Modeling the dynamical behavior of the interaction of T-cells and human immunodeficiency virus with saturated incidence

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Communications in Theoretical Physics 2024年第3期76卷 1-14页

作者： Salah Boulaaras Rashid Jan Amin Khan Ali Allahem Imtiaz Ahmad salma bah.amand Department of Mathematics College of ScienceQassim UniversityBuraydah51452Saudi Arabia Institute of Energy Infrastructure(IEI) Department of Civil EngineeringCollege of EngineeringUniversiti Tenaga Nasional(UNITEN)Putrajaya CampusJalan IKRAM-UNITEN43000 KajangSelangorMalaysia Department of Mathematics University of SwabiSwabi 23561Pakistan Department of Mathematics College of SciencesQassim UniversitySaudi Arabia Institute of Informatics and Computing in Energy(IICE) Universiti Tenaga NasionalKajangSelangorMalaysia Department of Political Science Bacha Khan University CharsaddaCharsadda 24420KPK Pakistan

In the last forty years,the rise of HIV has undoubtedly become a major concern in the field of public health,imposing significant economic burdens on affected ***,it becomes imperative to undertake comprehensive investigations into the mechanisms governing the dissemination of HIV within the human *** this work,we have devised a mathematical model that elucidates the intricate interplay between CD4^(+)T-cells and viruses of HIV,employing the principles of fractional *** production rate of CD4^(+)T-cells,like other immune cells depends on certain factors such as age,health status,and the presence of infections or ***,we incorporate a variable source term in the dynamics of HIV infection with a saturated incidence rate to enhance the precision of our *** introduce the fundamental concepts of fractional operators as a means of scrutinizing the proposed HIV *** facilitate a deeper understanding of our system,we present an iterative scheme that elucidates the trajectories of the solution pathways of the *** show the time series analysis of our model through numerical findings to conceptualize and understand the key factors of the *** addition to this,we present the phase portrait and the oscillatory behavior of the system with the variation of different input *** information can be utilized to predict the long-term behavior of the system,including whether it will converge to a steady state or exhibit periodic or chaotic oscillations.

关键词： HIV infection fractional-calculus dynamics of HIV iterative scheme dynamical behaviour mathematical model fractional derivatives

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Fortifying Healthcare Data Security in the Cloud:A Comprehensive Examination of the EPM-KEA Encryption Protocol

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Computers, Materials & Continua 2024年第5期79卷 3397-3416页

作者： Umi salma Basha Shashi Kant Gupta Wedad Alawad SeongKi Kim Salil Bharany Computer Science and Information Technology Jazan UniversityJazanSaudi Arabia CSE Eudoxia Research UniversityNew CastleUSA Department of Information Technology College of Computer ScienceQassim UniversityBuraydahSaudi Arabia National Center of Excellence in Software Sangmyung UniversitySeoulKorea Department of Computer Science and Engineering Lovely Professional UniversityPhagwaraPunjabIndia

A new era of data access and management has begun with the use of cloud computing in the healthcare *** the efficiency and scalability that the cloud provides, the security of private patient data is still a majorconcern. Encryption, network security, and adherence to data protection laws are key to ensuring the confidentialityand integrity of healthcare data in the cloud. The computational overhead of encryption technologies could leadto delays in data access and processing rates. To address these challenges, we introduced the Enhanced ParallelMulti-Key Encryption Algorithm (EPM-KEA), aiming to bolster healthcare data security and facilitate the securestorage of critical patient records in the cloud. The data was gathered from two categories Authorization forHospital Admission (AIH) and Authorization for High Complexity *** use Z-score normalization forpreprocessing. The primary goal of implementing encryption techniques is to secure and store massive amountsof data on the cloud. It is feasible that cloud storage alternatives for protecting healthcare data will become morewidely available if security issues can be successfully fixed. As a result of our analysis using specific parametersincluding Execution time (42%), Encryption time (45%), Decryption time (40%), Security level (97%), and Energyconsumption (53%), the system demonstrated favorable performance when compared to the traditional *** suggests that by addressing these security concerns, there is the potential for broader accessibility to cloudstorage solutions for safeguarding healthcare data.

关键词： Cloud computing healthcare data security enhanced parallel multi-key encryption algorithm(EPM-KEA)

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A NovelMethod for Determining Tourism Carrying Capacity in a Decision-Making Context Using q−Rung Orthopair Fuzzy Hypersoft Environment

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Computer Modeling in Engineering & Sciences 2024年第2期138卷 1951-1979页

作者： salma Khan Muhammad Gulistan NasreenKausar Seifedine Kadry Jungeun Kim Department of Mathematics and Statistics Hazara UniversityMansehra21120Pakistan Department of Mathematics Faculty of Arts and SciencesYildiz Technical UniversityEsenlerIstanbul34210Turkey Department of Applied Data Science Noroff University CollegeKristiansand4612Norway Artificial Intelligence Research Center(AIRC) Ajman UniversityAjman346United Arab Emirates Department of Electrical and Computer Engineering Lebanese American UniversityP.O.Box 13-5053ByblosLebanon Department of Software and CMPSI Konju National UniversityCheonan31080Korea

Tourism is a popular activity that allows individuals to escape their daily routines and explore new destinations for various reasons,including leisure,pleasure,or business.A recent study has proposed a unique mathematical concept called a q−Rung orthopair fuzzy hypersoft set(q−ROFHS)to enhance the formal representation of human thought processes and evaluate tourism carrying *** approach can capture the imprecision and ambiguity often present in human *** the advanced mathematical tools in this field,the study has also incorporated the Einstein aggregation operator and score function into the q−ROFHS values to supportmultiattribute decision-making *** implementing this technique,effective plans can be developed for social and economic development while avoiding detrimental effects such as overcrowding or environmental damage caused by tourism.A case study of selected tourism carrying capacity will demonstrate the proposed methodology.

关键词： q−Rung orthopair fuzzy hypersoft set decision-making tourism carrying capacity aggregation operator

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Osteoarthritis versus psoriasis arthritis: Physiopathology, cellular signaling, and therapeutic strategies

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Genes & Diseases 2024年第3期11卷 232-247页

作者： salma Nassor Juma Junguang Liao Yuping Huang Rexhina Vlashi Qingwan Wang Bocong Wu Dan Wang Mengrui Wu Guiqian Chen College of Life Science and Medicine Zhejiang Provincial Key Laboratory of Silkworm Bioreactor and BiomedicineZhejiang Sci-Tech UniversityHangzhouZhejiang 310018China Department of Cell and Developmental Biology College of Life SciencesZhejiang UniversityHangzhouZhejiang 310058China

Osteoarthritis and psoriasis arthritis are two degenerative forms of arthritis that share similar yet also different manifestations at the histological,cellular,and clinical *** have marked them as two entirely distinct *** recent dis-coveries in disease initiation and progression,potential mechanisms,cellular signaling path-ways,and ongoing clinical therapeutics,there are now more opportunities for discovering osteoarthritis *** review summarized the osteoarthritis and psoriasis arthritis signaling pathways,crosstalk between BMP,WNT,TGF-β,VEGF,TLR,and FGF signaling pathways,bio-markers,and anatomical *** bench research,we demonstrated that regen-erative medicine is a promising alternative for treating osteoarthritis by highlighting significant scientific discoveries on entheses,multiple signaling blockers,and novel molecules such as immunoglobulin new antigen receptors targeted for potential drug ***,we offered valuable therapeutic approaches with a multidisciplinary strategy to treat patients with osteoarthritis or psoriasis arthritis in the coming future in the clinic.

关键词： Newantigen receptor Osteoarthritis Physiopathology Psoriasisarthritis Signaling pathway

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Differential leaf flooding resilience in Arabidopsis thaliana is controlled by ethylene signalingactivated and age-dependent phosphorylation of ORESARA1

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Plant Communications 2024年第6期5卷 73-88页

作者： Tom Rankenberg Hans van Veen Mastoureh Sedaghatmehr Che-Yang Liao Muthanna Biddanda Devaiah Evelien AStouten salma Balazadeh Rashmi Sasidharan Plant Stress Resilience Utrecht UniversityPadualaan 83584 CH Utrechtthe Netherlands Evolutionary Plant-Ecophysiology Groningen Institute for Evolutionary LIfe SciencesNijenborgh 79747 AG Groningenthe Netherlands Max Planck Institute of Molecular Plant Physiology Am Muhlenberg 114476 PotsdamGermany Experimental and Computational Plant Development Utrecht UniversityPadualaan 83584 CH Utrechtthe Netherlands Leiden University Leidenthe Netherlands

The phytohormone ethylene is a major regulator of plant adaptive responses to *** flooded plant tissues,ethylene quickly increases to high concentrations owing to its low solubility and diffusion rates in *** accumulation in submerged plant tissues makes it a reliable cue for triggering flood acclimation responses,including metabolic adjustments to cope with flood-induced ***,persistent ethylene accumulation also accelerates leaf ***-induced senescence hampers photosynthetic capacity and stress *** submerged Arabidopsis,senescence follows a strict age-dependent pattern starting with the older *** mechanisms underlying ethylene-mediated senescence have been uncovered,it is unclear how submerged plants avoid indiscriminate breakdown of leaves despite high systemic ethylene *** demonstrate that although submergence triggers leaf-age-independent activation of ethylene signaling viaEIN3 in Arabidopsis,senescence is initiated only inold ***3 stabilization also leads to overall transcript and protein accumulation of the senescence-promoting transcription factor ORESARA1(ORE1)in both old and young leaves during ***,leaf-age-dependent senescence can be explained by ORE1 protein activation via phosphorylation specifically in old leaves,independent of the previously identifiedage-dependentcontrol of ORE1 viami R164.A systematic analysis of the roles of the majorflooding stresscuesand signalingpathways shows that only the combination of ethylene and darkness is sufficientto mimic submergence-induced senescence involving ORE1 accumulation and ***,most of ten associated with flooding stress in plants,appears to have no role in these *** results reveal a mechanism by which plants regulate the speed and pattern of senescence during environmental stresses such as ***-dependent ORE1 activity ensures that older,expendable leaves are dismantled firs

关键词： ﬂooding abiotic stress hypoxia senescence ethylene

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Capparis spinosa L waste activated carbon as an efficient adsorbent for crystal violet toxic dye removal: Modeling, optimization by experimental design, and ecological analysis

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Chinese Journal of Chemical Engineering 2024年第7期71卷 283-302页

作者： Mohammed Benjelloun Youssef Miyah salma Ssouni Soulaiman Iaich Mohamed El-habacha Salek Lagdali Khadija Saka El Mustafa Iboustaten Abdelaziz Ait Addi Sanae Lairini Rabia Bouslamti Laboratory of Materials ProcessesCatalysisand EnvironmentHigher School of TechnologySidi Mohamed Ben Abdellah UniversityFez 30070Morocco Ministry of Health and Social Protection Higher Institute of Nursing Professions and Health TechniquesFez/Meknes 30070Morocco Laboratory of Biochemistry Faculty of MedicinePharmacy and DentistrySidi Mohamed Ben Abdellah UniversityFez 30070Morocco Laboratory of Applied Chemistry and Environment Faculty of SciencesIbnou Zohr UniversityAgadir 80322Morocco Research Team of Energy and Sustainable Development Higher School of TechnologyIbnou Zohr UniversityGuelmim 81000Morocco Organic Chemistry and Physical Chemistry Laboratory Faculty of SciencesIbnou Zohr UniversityAgadir 80322Morocco

Textile dyes are dramatic sources of pollution and non-aesthetic disturbance of aquatic life and therefore represent a potential risk of bioaccumulation that can affect living *** is imperative to reduce or eliminate these dyes from liquid effluents with innovative biomaterials and ***,this research aims to highlight the performance of Capparis spinosa L waste-activated carbon(CSLW-AC)adsorbent to remove crystal violet(CV)from an aqueous *** mechanism of CV adsorption on CSLW-AC was evaluated based on the coupling of experimental data and different characterization *** efficiency of the CSLW-AC material reflected by the equilibrium adsorption capacity of CV could reach more than 195.671 mg·g^(–1) when 0.5 g·L^(–1) of CSLW-AC(Particle size≤250μm)is introduced into the CV of initial concentration of 100 mg·L^(–1) at pH 6 and temperature 65℃ and in the presence of potassium ions after 60 min of contact time according to the one parameter at a time *** adsorption behavior of CV on CSLW-AC was found to be consistent with the pseudo-second-order kinetic model and Frumkin's linear isothermal *** thermodynamic aspects indicate that the process is physical,spontaneous,and *** optimization of the process by the Box Behnken design of experiments resulted in an adsorption capacity approaching 183.544 mg·g^(–1)([CV]=100 mg·L^(–1) and[CSLW-AC]=0.5 g·L^(–1) at 35 min).The results of the Lactuca sativa seeds germination in treated CV(70%),adsorbent solvent and thermal regeneration(more than 5 cycles),and process cost analysis(1.0484 USD·L^(–1))tests are encouraging and promising for future exploitations of the CSLW-AC material in different industrial fields.

关键词： Box Behnken Capparis spinosa L waste-activated carbon Cost analysis Isotherm Kinetic Regeneration

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Seismicity patterns before the 2021 Fin (Iran) doublet earthquakes using the region-time-length and time-to-failure methods

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Earthquake Science 2024年第4期37卷 324-336页

作者： salma Ommi Vladimir Borisovich Smirnov Department of Environmental Planning and Design Environmental Science Research InstituteShahid Beheshti UniversityTehranIran Department Physic of The Earth Moscow State UniversityMoscowRussia Schmidt Institute of Physics of the Earth Russian Academy of SciencesMoscowRussia

Knowledge regarding earthquake hazards and seismicity is crucial for crisis management, and the occurrence of foreshocks, seismic activity patterns, and spatiotemporal variations in seismic activity have been studied. Furthermore, the estimation of the region-time-length (RTL) parameter has been proposed to detect seismic quiescence before the occurrence of a large earthquake. In addition, the time-to-failure method has been used to estimate the time occurrence of large earthquakes. Hence, in this study, to gain deeper insight into seismic activity in the southern Zagros region, we utilized the RTL algorithm to identify the quiescence and activation phases leading to the Fin doublet earthquakes. Temporal variations in the RTL parameter showed two significant anomalies. One corresponded to the occurrence time of the first earthquake (2017-12-12);the other anomaly was associated with the occurrence time of the second event (2021-11-14). Based on a negative value of the RTL parameter observed in the vicinity of the Fin epicenters (2021), seismic quiescence (a decrease in seismicity compared to the preceding background rate) was identified. The spatial distribution of the RTL prognostic parameters confirms the appearance of seismic quiescence surrounding the epicenter of the Fin doublet earthquakes (2021). The time-to-failure method was designed using precursory events that describe the acceleration of the seismic energy release before the mainshock. Using the time-to-failure method for the earthquake catalog, it was possible to estimate both the magnitude and time of failure of the Fin doublet. Hence, the time-tofailure technique can be a useful supplementary method to the RTL algorithm for determining the characteristics of impending earthquakes.

关键词： earthquake catalog seismic quiescence region-time-length(RTL)algorithm time-to-failure method Fin doublet earthquakes.

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Peaches pulp(Prunus persica L.) mitigate type 2 diabetic mice by modulating of glucose metabolism and gut microbiota

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Food Science and Human Wellness 2024年

作者： Leyi Zhou Jianfen Ye Yingying Wei Mouayche salma Shu Jiang Yi Chen Xingfeng Shao State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products， Zhejiang-Malaysia Joint Research Laboratory for Agricultural Product Processing and Nutrition， College of Food Science and Engineering， Ningbo University

Peach are a fruit with high nutritional and economic value， but their safety and suitability for diabetic patients have been questioned. This study investigated the effects and potential mechanisms of peach pulp (PP) on type 2 diabetes mellitus (T2DM) in mice induced by a high-fat diet (HFD) combined with streptozotocin (STZ). The results showed that PP alleviated hyperglycemia， hyperlipidemia， hyperuricemia， and tissue dysfunction in T2DM mice through the synergistic effect of nutrients and non-nutrient compounds. Analysis of mRNA expression levels revealed that PP improved glucose metabolism in T2DM mice by promoting glycogen synthesis and inhibiting gluconeogenesis. Furthermore， elevated levels of PP resulted in an increase in acetic acid content following a 4 weeks intervention period. Additionally， it led to the restoration of gut microbiota balance by decreasing the Firmicutes/Bacteroidota (F/B) ratio and enhancing the presence of Romboutsia， Allobaculum， Alloprevotella， and Bacteroides after an 8 weeks intervention. Ultimately， our results suggest that PP may offer advantages for individuals with diabetes.

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Effect of PKD1L1 Mutation on its Interaction with PKD2 to Cause Situs Inversus Totalis

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Journal of Clinical and Nursing Research 2024年第8期8卷 183-206页

作者： Fatima Haroon salma Saeed Khan Assad Ullah Institute of Molecular Biology and Biotechnology(IMBB) the University of LahorePakistan Biomedical and Life Sciences Kohsar University MurreeMurree 47150PunjabPakistan Department of Biosciences COMSATS University IslamabadPark RdIslamabad Capital Territory 45550Pakistan

Situs inversus totalis(SIT)is a rare homozygous recessive disease caused by the mutation in PKD1L1,which is required for normal interaction with PKD2 and leads to different complications such as respiratory disorders,brain disorders and even *** present study was designed to find out the mutational effect on the binding of PKD2 with mutated PKD1L1,which leads to *** three-dimensional(3D)structure of wild type and mutated PKD1L1 was predicted with>90%confidence using different online *** different online tools that were employed were SWISS-MODEL,Phyre2(normal&intensive)and *** compute the physiochemical properties of PKD1L1(wild&mutated)and PKD2 in silico approaches were employed using the ExPASy ProtParam *** properties such as molecular weight,isoelectric point,the total number of negatively and positively charged residues,extinction coefficient,half-life,instability and aliphatic index,grand average of hydropathicity,and amino acid percentage were calculated.A lot of variability was observed in these parameters among PKD1L1 and PKD2,which accounted for diversification in their functional *** theoretical pI points showed that PKD1L1(whole)is more basic with 6.64 pI compared to its first chain TOPO_DOM(amino acids from 1–1748)has a pI of 5.62 which means it is basic while PKD2 have the lowest pI point of *** was performed using the PatchDock and ClusPro online tools.

关键词： SIT PKD1L1 PKD2 SWISS-MODEL ClusPro

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