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Non-Chemotherapy Medullary Aplasia in the Pediatric Oncology Unit of the Gabriel Touré Teaching Hospital, Bamako

Open Journal of Pediatrics 2023年第6期13卷 798-806页

作者： Pierre Togo Ibrahim Ahamadou Tati Simaga Abdoul Karim Doumbia Fousseyni Traoré Oumar Coulibaly Djénéba Konaté salif zigmé Adama Dembélé Mohamed Elmouloud Cissé Belco Maïga Karamoko Sacko Hawa Gouro Diall Boubacar Ali Touré Amadou Touré Yacouba Aba Coulibaly Aminata Doumbia Hawa Konaré Kalirou Traoré Souleymane Sagara Abdoul Aziz Diakité Fatoumata Dicko Cheick Bougadari Traoré Boubacar Togo Department of Pediatrics Gabriel Touré Teaching Hospital Bamako Mali National Institute for Training in Health Sciences Bamako Mali Center for Research and Fight against Sickle Cell Disease Bamako Mali Pathological Anatomy Department Point G Teaching Hospital Bamako Mali

Objectives: The main objective was to study the epidemiological, diagnostic and therapeutic aspects of medullary aplasia (MA). Methods: This was a prospective and descriptive retro study conducted from January 1, 2008 to December 31, 2018 in the pediatric oncology unit of the pediatrics department of the Gabriel Touré teaching Hospital in Bamako. Results: We collected 29 children’s cases out of 1632 admissions during the study period, representing a frequency of 1.8% and an incidence of 2.6 cases per year. The sex ratio was 2.6. The 11 - 15 age group accounted for 45%, with an average age of 8.93 years. The majority of fathers (55.2%) and mothers (62.1%) had received no education;they were mainly farmers (62.1%) and housewives (86.2%). The average consultation time was 92.21 days. Anemia was the reason for consultation in 69% of cases. Pallor was present on admission in 96.5%;infectious syndrome accounted for 79.3%, anemic syndrome for 51.7% and hemorrhagic syndrome for 27.6%;the three syndromes were associated in 27.6%. Malaria was associated with bone marrow aplasia in 58.6%. Anemia was present in 93.1%, neutropenia in 65.5% and thrombocytopenia in 86.2%. All had received a labile blood product (LBP) transfusion, and 24 (83%) had received antibiotics. Patients were treated with corticosteroids (58.6%), androgens (20.7%) and immunosuppressants (20.7%). The death rate was 34.6%. At last count, 15 (83%) had discontinued treatment, 2 (11%) were undergoing treatment and 1 (6%) was in remission. Conclusion: Effective treatment of MA requires improved technical facilities and better economic conditions for parents.

关键词： Medullar Aplasia Children Bamako

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Global Dryland Ecosystem Programme(G-DEP):Africa consultative meeting report

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Journal of Arid Land 2020年第3期12卷 538-544页

作者： PENG Yu FU Bojie ZHANG Linxiu YU Xiubo FU Chao salif DIOP Hubert HIRWA Aliou GUISSE LI Fadong State Key Laboratory of Ecosystem Network Observation and Modeling Institute of Geographic Sciences and Natural Resources ResearchChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China State Key Laboratory of Urban and Regional Ecology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China International Ecosystem Management Partnership United Nations Environment ProgrammeBeijing 100101China National Academy of Sciences of Senegal P.O.Box 4344 Dakar RPSenegal Faculty of Science and Technology University Cheikh Anta Diop of DakarP.O.Box 5005 Dakar-FannSenegal

In order to enhance and restore the ecosystems of natural capital in African arid regions,the Global Dryland Ecosystem Programme(G-DEP)consultative meeting was hosted in Dakar,Senegal,from 23 to 25 September *** paper details the first African meeting of the *** meeting reviewed preceding dryland ecosystems case studies,identified vulnerable arid and semi-arid regions,and proposed sustainable solutions to *** also identified the successes and failures of previous attempts to improve vulnerable ecosystems and ultimately formed an action plan to improve these ***,ecosystems,and livelihoods for Sustainable Development Goals(SDGs),Great Green Wall Initiative(GGWI)for Sahara and Sahel,and China-Africa cooperation on science,technology,and innovation are three extra main sections concerned of the ***,more specific topics as the complicated relationship between these natural processes and human activity,including pastoralism,soil restoration,and vegetation regenerate techniques,were fully *** meeting also identified the positive effects international collaboration can have on dryland regions,specifically in the capacity of sharing information,technology,and innovation on purpose to develop a joint proposal for long-term research programs in African arid and semi-arid ***,meetings that review the progress made on ecosystem management for the sustainable livelihoods in Africa,identification of priority areas,and the development and implementation of ecosystem programs for proper research and collaboration in African arid and semi-arid zones,have been proposed as strategic recommendations to enhance the global partnership for sustainable ***,as the outcomes of the workshop,there are three steps proposed to handle African dryland climate changes,several aspects suggested to solve current dilemmas of the GGWI,and a series of actions recommended for G-DEP related activities

关键词： Africa Global Dryland Ecosystem Programme(G-DEP) dryland ecosystem consultation Sustainable Development Goals Great Green Wall Initiative(GGWI)

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Gross Alpha and Beta Activities and Related Lifetime Risks Assessment Due to Ingestion of Drinking Water from Different Sources in the District of Abidjan, Cote d’Ivoire

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World Journal of Nuclear Science and Technology 2024年第1期14卷 86-96页

作者： Ponaho Claude Kezo Issa Konate Dabo salif Ignace Agba Laboratory of Environmental Science and Technology University Jean Lorougnon Guede (UJLoG) Daloa C&#244te d’Ivoire Laboratory of Environmental and Solar Energy Sciences University Felix Houphouet Boigny (UFHB) Abidjan C&#244te d’Ivoire Laboratory of Fundamental and Applied Physics University Nangui Abrogoua (UNA) Abidjan C&#244te d’Ivoire

Drinking good quality water is essential for better health. It is therefore essential to assess the radiological quality of all water consumed in the District of Abidjan in order to prevent related hazards. Thus, the objective of this study was to assess the risk of cancer due to the ingestion of alpha and beta emitting radionuclides in the different types of water consumed in the region. A total of 63 water samples with 43 tap water samples, 5 bottled mineral water and 15 sachet water samples was collected and taken to GAEC laboratory for analysis. The low background Gas-less Automatic Alpha/Beta counting system (Canberra iMaticTM) was used to determine alpha and beta activity concentrations. Activity concentrations of both gross alpha and gross beta obtained in water sample were respectively lower than the WHO recommended limits of 0.1 Bq/l and 1 Bq/l. Also, the annual effective dose and total equivalent effective dose found in mineral bottled water samples were higher than in other types of water. The assessment of radiological lifetime risk has shown values of cancer risk due to ingestion alpha and beta emitters lower than recommended limit. These results indicate that there is no health hazard associated to consumption of water in the District of Abidjan.

关键词： Gross Alpha and Beta Activities Drinking Water Effective Dose Radiological Lifetime Risks

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Establishment of a Model for the Calculation of the COP of a Solar Adsorption Refrigerator

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Smart Grid and Renewable Energy 2023年第11期14卷 197-208页

作者： Amadou Konfe Gilbert G. Nana salif Ouedraogo Sié Kam Laboratory of Thermal and Renewable Energies University Joseph Ki-Zerbo Ouagadougou Burkina Faso

This paper deals with the evaluation of the Coefficient of Performance (COP) of solar adsorption refrigeration. In the literature, simulation models to predict the thermal behaviour and the coefficient of performance of these systems are uncommon. This is why we suggest a model to simulate the operation of the machine in a typical hot and dry climate of the city of Ouagadougou. The objective is to provide a model for calculating the COP from the measurement of the ambient temperature and the irradiation of a given site. Starting from mathematical modelling, a resolution and simulation were made with COMSOL software based on the Dubinin-Astakhov adsorption model, the heat transfer balance equations, and the Linear Driving Force (LDF) model to describe the thermal behaviour of the system. A one-week measurement sequence on the adsorption solar refrigerator at the Albert Schweitzer Ecological Centre (CEAS) validated the numerical results. The measurement shows that for the days with high sunshine, the temperature of the reaction medium reaches 110°C, and the pressure reaches 500 mbar. This leads to a production of cold that allows it to reach the temperature of -5°C at the evaporator. Under these conditions, the COP is worth 14%. These results are obtained both by numerical simulation using the COMSOL 5.1 software and after a measurement session on the solar refrigerator available to the CEAS. We obtained an experimental and theoretical coefficient of performance varying between 9% and 14% with a difference of between 0% and 3%. We conclude that our model is suitable to estimate the COP of any device based on its thermal properties, the ambient temperature and the irradiation of a given site.

关键词： Solar Refrigeration Adsorption Coefficient of Performance Modelling

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How a Cancer Registry Was Set Up in Senegal: An Example to Follow for a Developing Country

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Journal of Cancer Therapy 2023年第9期14卷 382-389页

作者： salif Baldé Sokhna Diop Niang Oumar Ba Mamadou Diop Joliot Curie Institute Aristide Le Dantec Hospital Dakar Senegal Departmentof Internal Medicine Dalal Jamm Hospital Dakar Senegal Department of Internal Medicine Idrissa Pouye Hospital Dakar Senegal

Objectives: Senegal, with the support of WHO, had begun the establishment of a National Cancer Registry in 2009, although it had been at a standstill since 1969;the objective of this work was to test the reliability of data collection tools and feasibility stages necessary for the validation of media before the establishment of a national cancer registry. Methodology: We conducted a non-exhaustive preliminary study over a period of three months from the first of January to 31 March 2010 at four major hospitals in Dakar at the time. Results: Two hundred and eighty-nine cases had been identified: 44% of men (n = 127) and 56% of women (n = 162) with a sex ratio of 0.8. The ages ranged from 20 to 90 years with an average of 50 years. The main diagnostic mode was essentially histological, with 76% of cases (n = 219). The most frequent locations were: ORL (ENT meaning Ear, Nose and Throat) with 25% of cases, liver 7% and bronchopulmonary 4.5% of cases. In men, liver cancer was the most common location and women for cervical cancer with 16%. Squamous cell carcinoma was the most common histological type with 68% of cases followed by adenocarcinoma with 22% of cases. Thirty-eight percent of patients were classified as stage III and IV. A quarter of our patients had received palliative treatment. In contrast, 15 (15%) had received chemotherapy and 4% had received radiotherapy. Data collection was satisfactory. Conclusion: Cancer is a reality in Senegal but it remains underdiagnosed. The materials made it possible to make the cancer registry effective throughout the country.

关键词： Registry Cancer Senegal

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Spontaneous Pneumothorax Complicating Miliary Tuberculosis: About a Case at the “Centre Medical Principal De La Gendarmerie Nationale Du Mali”

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Journal of Tuberculosis Research 2023年第2期11卷 67-73页

作者： Souleymane Coulibaly Marius Pembé Sanou Kassim Sidibe Ladji Mohamed Diaby Lassina Diallo Daouda Amara Traore salif Kone Ami Diarra salif Sow Abasse Sanogo salif Satao Mamadou Cherif Kante Mahamadou Coulibaly Aminata Bagayoko Soumaila Keita Polyclinique des Armées Kati Mali Centre Médical Principal de la Gendarmerie Nationale Bamako Mali Centre Médico-Chirurgical des Armées Bamako Mali Service de Pneumologie CHU Point G Bamako Mali

Introduction: Spontaneous pneumothorax is a rare but serious complication of tuberculosis. Miliary tuberculosis (MT) is a severe form of tuberculosis secondary to hematogenous spread of Mycobacterium tuberculosis. Objective: To report a case of MT complicated by pneumothorax. Methodology: This was a 25-year-old patient, farmer, followed up at the Pneumo-phtisiology department of the CHU du Point G for MT whose condition was improving after the introduction of anti-tuberculosis chemotherapy. He consulted again after experiencing chest pain. Clinical and imaging revealed a Spontaneous pneumothorax complicating MT. The treatment combined anti-tuberculosis chemotherapy, chest drainage and respiratory physiotherapy. Outcome was favorable with improvement of clinical and radiological signs. Conclusion: Pneumothorax complicating MT requires a reflective diagnostic approach and rapid management to improve its prognosis.

关键词： Spontaneous Pneumothorax Miliary Tuberculosis Antituberculous Chemotherapy Pleural Drainage Respiratory Physiotherapy

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Effect of Physical and Geometrical Parameters on Nuselt Number

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Open Journal of Fluid Dynamics 2022年第2期12卷 154-167页

作者： Momath Ndiaye Madialène Sene Mamadou salif Mané Goumbo Ndiaye Laboratory of Fluid Mechanics Hydraulics and Transfers Faculty of Science and Technology University Cheikh Anta Diop of Dakar Dakar Senegal Hydraulics Rural Engineering Machinery and Renewable Energies Training and Research Unit University of Sine Saloum El Hadj Ibrahima NIASS Kaolack Senegal Faculty of Sciences and Techniques Cheikh Anta Diop of Dakar Dakar Senegal Sen’eau Dakar Senegal

The results of this study show that the Nusselt number decreases with the increase of the dimensionless thermal conductivity and the Prandtl, Froude numbers. The increased Reynolds, Jacob numbers and the dimensionless... 详细信息

关键词： Condensation Forced Convection Vertical Wall Nusselt Number

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Characterization of Oils Produced from Jatropha Curcas, Peanut and White Sesame in Burkina Faso for Possible Enable Synthesis of Biofuels

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Journal of Power and Energy Engineering 2022年第5期10卷 39-53页

作者： Momath Ndiaye Madialène Sene Goumbo Ndiaye Mamadou salif Mané Hydraulics Rural Engineering Machinery and Renewable Energies Training and Research Unit University of Sine Saloum El Hadj Ibrahima NIASS Kaolack Senegal Sen’eau Dakar Senegal Faculty of Sciences and Techniques Cheikh Anta Diop of Dakar Dakar Senegal

The indispensable role of energy in the correct functioning of economies and the current depletion of fossil fuels which are not renewable, have made the search for alternative energy sources a major point of reflection worldwide. Vegetable oils are increasingly being considered as a possible replacement for fossil fuels in countries of the south and North. In order to vulgarize the use of vegetable oil as fuel, it is essential that analytical protocols and standards are elaborated to assure the quality of oils as fuels. This work aims at developing protocols for the characterization of oilseeds and their resultant oils in a bid to ensure their quality for direct use as Biofuels or better still to serve as raw material in producing Biofuels. These protocols have the advantage of being reproducible, fast, and simple to implement compared to those used in Europe to characterize the oils (very complex and expensive, applied to petroleum products). Cotton, Jatropha curcas, white sesame, and peanut grains were acquired from the Zogona local market, Ouagadougou, and oil extraction was done at the village level. The resultant oils were characterized. Their physicochemical parameters (water content, oil content, acid index, the calorific value, density, and viscosity....) were evaluated at the Biomass Energy and Biofuels Laboratory (LBEB) of the International Institute for Water and Environmental Engineering (2iE) and the Burkinabé National Hydrocarbons Authority (SONABHY) Laboratory. The oilseed grain cakes (moisture, ash rate, rate of volatile matter, and oil content...) were also analysed.

关键词： Biomass Oleaginous Physical Parameters Chemical Parameters Biofuel Vegetable Oils

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Influence of Fresh Water on Microbubble Generation in an Airlift Column Applied to Aquaculture: Extraction Capacity

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Open Journal of Applied Sciences 2022年第11期12卷 1809-1823页

作者： Djimako Bongo Nekoulnang Djetounako Clarisse Edith Kadjangaba salif Gaye Jean-Yves Champagne Higher Normal School of Technology of Sarh Sarh Chad Paleontology Department National Research Center for Development of N’djamena N’djamena Chad Faculty of Sciences and Techniques University of Doba Doba Chad LME Materials and Energetics Laboratory University Institute of Technology Thiès Senegal Laboratory of Fluid Mechanics and Acoustics INSA-Lyon Lyon France

Bubble flows consist a liquid phase and a gaseous phase dispersed as bubbles. They occur in nature and in many industrial applications, such as oil transportation in pipelines and steam generators for power generation. Due to large difference in density between gas and liquid, the flottability force causes bubbles to rise, which in turn can generate overall motion and agitation in liquid. This use of gravity as a flow driver, which is specific to disperse phase systems, is used in process engineering (bubble columns and gasosiphon) to sparingly promote mixing and exchange between gas and liquid. In many applications, bubbles are used to agitate a liquid in order to promote mixing and transfers. This work is devoted to study of hydrodynamics of a bubble column. Experimentally, we have determined properties fluctuations of velocities inside the aquarium of rising homogeneous bubbles for different bubble sizes and vacuum rates. The interfacial area between gas and liquid phase is a crucial factor for mass transfer in bubble columns. The molecular exchange between a given volume of gas and water can be enhanced by formation of smaller bubbles, leading to a larger gas-liquid interface. This work presents the various physical phenomena that apply to bubbles, as well as associated dimensionless numbers. A state art of Micro-Bubble Generators (MBG) is then presented, presenting systems using various phenomena such as cavitation, electrolysis, or shear.

关键词： Vacuum Airlift Column MIBC Casein Turbidity Surfactant Coalescence

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Approach Thermal Habitat Assessment in N’Djamena in Chad

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World Journal of Engineering and Technology 2016年第1期4卷 82-102页

作者： Ahmat Charfadine Mahamat Barka Abakar Mahamat Tahir Mohagir Ahmed Mohammed Pr. salif Gaye Laboratory of Renewable Energy and Materials Premises of the University of N’Djamena N’Djamena Chad Laboratory of Materials Mechanics and Hydraulics of the University of Thies Thies Senegal

For the earth material construction is the most used one in Chad, the object of this work is the assessment of the thermal quality of earthen adobe mixed with straw. Different simulation software analyzes the CoDyBa which is conducted to determine the behavior of this material compared to living comfort thanks to the Fanger model, which is a method of approach to thermal comfort standpoint. The study focused on two configurations on the formation of the walls of a room. The first of these configurations led to the definition of a first cell constructed earthen adobe named Batter roofing sheet aluminum and a second cell built in blocks named Batbet which had the same geometric characteristics (thickness, dimensions and side openings) and covered in the same manner as the ground cell. The different comfort indices PMV and PPD values of these two configurations of habitat were identified and were used to determine their thermal comfort rating.

关键词： Habitat Assessment Habitat Suitability Building Monitoring Climate Change Thermal Habitat Orientation Solar

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