检索结果-南通市图书馆

Transcriptomic and Macroscopic Architectures of Multimodal Covariance Network Reveal Molecular–Structural–Functional Co-alterations

引用

Research 2024年第1期2023卷 471-487页

作者： Lin Jiang Yueheng Peng Runyang He Qingqing Yang Chanlin Yi Yuqin Li bin Zhu Yajing Si Tao Zhang bharat b.biswal dezhong Yao Lan Xiong Fali Li Peng Xu The Clinical Hospital of Chengdu brain Science Institute MOE Key Lab for NeuroinformationUniversity of Electronic Science and Technology of ChinaChengdu 611731China School of Life Science and Technology Center for Information in BioMedicineUniversity of Electronic Science and Technology of ChinaChengdu 611731China School of Psychology Xinxiang Medical UniversityXinxiang 453003China School of Science Xihua UniversityChengdu 610039China department of biomedical Engineering New Jersey Institute of TechnologyNewarkNJUSA School of Electrical Engineering Zhengzhou UniversityZhengzhou 450001China Research Unit of NeuroInformation Chinese Academy of Medical Sciences2019RU035ChengduChina Montreal Neurological Institute and Hospital McGill UniversityMontrealQCCanada department of Electrical and Computer Engineering Faculty of Science and TechnologyUniversity of MacaoMacaoChina Radiation Oncology Key Laboratory of Sichuan Province 610041 ChengduChina Rehabilitation Center Qilu Hospital of Shandong UniversityJinan 250012China

Human cognition is usually underpinned by intrinsic structure and functional neural co-activation in spatially distributed brain *** to lacking an effective approach to quantifying the covarying of structure and functional responses,how the structural–functional circuits interact and how genes encode the relationships,to deepen our knowledge of human cognition and disease,are still ***,we propose a multimodal covariance network(MCN)construction approach to capture interregional covarying of the structural skeleton and transient functional activities for a single *** further explored the potential association between brain-wide gene expression patterns and structural–functional covarying in individuals involved in a gambling task and individuals with major depression disorder(Mdd),adopting multimodal data from a publicly available human brain transcriptomic atlas and 2 independent *** analysis showed a replicable cortical structural–functional fine map in healthy individuals,and the expression of cognition-and disease phenotype-related genes was found to be spatially correlated with the corresponding MCN *** analysis of cell type-specific signature genes suggests that the excitatory and inhibitory neuron transcriptomic changes could account for most of the observed correlation with task-evoked MCN differences.

关键词： alterations evoked spatially

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Efficient guiding and focusing of intense laser pulse using periodic thin slits

引用

Matter and Radiation at Extremes 2024年第4期9卷 29-39页

作者： L.Xu T.W.Huang K.Jiang C.N.Wu H.Peng P.C.hen R.Li H.b.Zhuo C.T.Zhou Shenzhen Key Laboratory of Ultraintense Laser and Advanced Material Technology Center for Intense Laser ApplicationTechnologyand College of Engineering PhysicsShenzhen Technology UniversityShenzhen 518118People’s Republic of China

Slits have been widely used in laser-plasma interactions as plasma optical components for generating high-harmonic light and controlling laser-driven particle ***,we propose and demonstrate that periodic thin slits can be regarded as a new breed of optical elements for efficient focusing and guiding of intense laser *** fundamental physics of intense laser interaction with thin slits is studied,and it is revealed that relativistic effects can lead to enhanced laser focusing far beyond the pure diffractive focusing *** addition,the interaction of an intense laser pulse with periodic thin slits makes it feasible to achieve multifold enhancement in both laser intensity and energy transfer efficiency compared with conventional *** results provide a novel method for manipulating ultra-intense laser pulses and should be of interest for many laser-based applications.

关键词： laser pulse intense

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hydrocarbon indication in Rio bonito Formation sandstone:Implication for CO_(2)storage in São Paulo,brazil

引用

Energy Geoscience 2024年第1期5卷 331-341页

作者： Richardson M.Abraham-A Haline V.Rocha Saulo b.de Oliveira Colombo C.G.Tassinarri Orlando C.da Silva Institute of Energy and Environment University of São PauloSão PauloBrazil Research Centre for Greenhouse Gas Innovation University of São PauloSão PauloBrazil

São Paulo State has witnessed CO_(2)storage-based investigations considering the availability of suitable geologic structures and proximity to primary CO_(2)source sinks related to bioenergy and carbon capture and storage(bECCS)*** current study presents the hydrocarbon viability evaluations and CO_(2)storage prospects,focusing on the sandstone units of the Rio bonito *** objective is to apply petrophysical evaluations with geochemical inputs in predicting future hydrocarbon(gas)production to boost CO_(2)storage within the study *** study used data from eleven wells with associated wireline logs(gamma ray,resistivity,density,neutron,and sonic)to predict potential hydrocarbon accumulation and fluid mobility in the investigated *** samples(shale and carbonate)obtained from depths>200 m within the study location have shown bitumen *** geochemistry data of the Rio bonito Formation shale beds suggest they are potential hydrocarbon source rocks and could have contributed to the gas accumulations within the sandstone *** drilled well data,e.g.,Cb-1-SP and TI-1-SP,show hydrocarbon(gas)presence based on the typical resistivity and the combined neutron-density responses at depths up to 3400 m,indicating the possibility of other hydrocarbon members apart from the heavy oil(bitumen)observed from the near-surface rocks *** the three-dimensional(3-d)model,the free fluid indicator(FFI)is more significant towards the southwest and southeast of the area with deeper depths of occurrence,indicating portions with reasonable hydrocarbon recovery rates and good prospects for CO_(2)injection,circulation and permanent ***,future studies based on contemporary datasets are required to establish the hydrocarbon viability further,foster gas production events,and enhance CO_(2)storage possibilities within the region.

关键词： Paranábasin Hydrocarbon indication Sandstone reservoirs Rio bonito Formation CO_(2)storage Hydrocarbon recovery factor Fluid injection rate

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

APIR:Aggregating Universal Proteomics database Search Algorithms for Peptide Identification with FdR Control

引用

Genomics, Proteomics & bioinformatics 2024年第2期22卷 171-187页

作者： Yiling Elaine Chen Xinzhou Ge Kyla Woyshner MeiLu Mcdermott Antigoni Manousopoulou Scott b.Ficarro Jarrod A.Marto Kexin Li Leo david Wang Jingyi Jessica Li department of Statistics and data Science University of CaliforniaLos AngelesCA 90095USA department of Immuno-Oncology Beckman Research InstituteCity of Hope National Medical CenterDuarteCA 91010USA department of Quantitative and Computational biology University of Southern CaliforniaLos AngelesCA 90089USA department of Cancer biology and blais Proteomics Center Dana-Farber Cancer InstituteDepartment of PathologyBrigham and Women’s Hospital and Harvard Medical SchoolBostonMA 02215USA department of Pediatrics City of Hope National Medical CenterDuarteCA 91010USA bioinformatics Interdepartmental Program University of CaliforniaLos AngelesCA 90095USA department of Human Genetics University of CaliforniaLos AngelesCA 90095USA department of Computational Medicine University of CaliforniaLos AngelesCA 90095USA department of biostatistics University of CaliforniaLos AngelesCA 90095USA

Advances in mass spectrometry(MS)have enabled high-throughput analysis of proteomes in biological *** state-of-the-art MS data analysis relies on database search algorithms to quantify proteins by identifying peptide–spectrum matches(PSMs),which convert mass spectra to peptide *** database search algorithms use distinct search strategies and thus may identify unique ***,no existing approaches can aggregate all user-specified database search algorithms with a guaranteed increase in the number of identified peptides and a control on the false discovery rate(FdR).To fill in this gap,we proposed a statistical framework,Aggregation of Peptide Identification Results(APIR),that is universally compatible with all database search ***,under an FdR threshold,APIR is guaranteed to identify at least as many,if not more,peptides as individual database search algorithms *** of APIR on a complex proteomics standard dataset showed that APIR outpowers individual database search algorithms and empirically controls the *** data studies showed that APIR can identify disease-related proteins and post-translational modifications missed by some individual database search *** APIR framework is easily extendable to aggregating discoveries made by multiple algorithms in other high-throughput biomedical data analysis,e.g.,differential gene expression analysis on RNA sequencing *** APIR R package is available at https://***/yiling0210/APIR.

关键词： Shotgun proteomics Peptide–spectrum match Peptide identification Aggregation of lists FdR control

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Highly enhanced UV absorption and light emission of monolayer WS_(2)through hybridization with Ti_(2)N MXene quantum dots and g-C_(3)N_(4)quantum dots

引用

Opto-Electronic Advances 2024年第6期7卷 31-39页

作者： Anir S.Sharbirin Rebekah E.Kong Wendy b.Mato Trang Thu Tran Eunji Lee Jolene W.P.Khor Afrizal L.Fadli Jeongyong Kim department of Energy Science Sungkyunkwan UniversitySuwon 16419Republic of Korea

Two-dimensional(2d)transition metal dichalcogenides(TMd)are atomically thin semiconductors with promising optoelectronic applications across the visible ***,their intrinsically weak light absorption and the low photoluminescence quantum yield(PLQY)restrict their performance and potential use,especially in ultraviolet(UV)wavelength light *** dots(Qd)derived from 2d materials(2d/Qd)provide efficient light absorption and emission of which energy can be tuned for desirable light *** this study,we greatly enhanced the photon absorption and PLQY of monolayer(1L)tungsten disulfide(WS_(2))in the UV range via hybridization with 2d/Qd,particularly titanium nitride MXene Qd(Ti_(2)N MQd)and graphitic carbon nitride Qd(GCNQd).With the hybridization of MQd or GCNQd,1LWS_(2)showed a maximum PL enhancement by 15 times with 300 nm wavelength excitation,while no noticeable enhancement was observed when the excitation photon energy was less than the bandgap of the Qd,indicating that UV absorption by the Qd played a crucial role in enhancing the light emission of 1L-WS_(2)in our 0d/2d hybrid *** findings present a convenient method for enhancing the photo-response of 1L-WS_(2)to UV light and offer exciting possibilities for harvesting UV energy using 1L-TMd.

关键词： monolayer TMd WS_(2) 2d-derived quantum dots UV absorption energy transfer

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

火星探测:黄钾铁矾原地K-Ar定年

引用

中国科学：地球科学 2024年第3期54卷 661-676页

作者：杨静郑德文武颖陈虹杨莉张斌中国地质科学院地质力学研究所自然资源部活动构造与地质安全重点实验室北京100081 中国地震局地质研究所地震动力学国家重点实验室北京100037 中国地质大学(北京)科学研究院北京100083 中国科学院地质与地球物理研究所中国科学院新生代地质与环境重点实验室北京100029

为了更好地确定火星不同地形所记录的气候变化的时间尺度,确定火星历史上重大事件的绝对年龄,并校准陨石坑率,需要从火星原地或从返回样品中获得精确的年龄数据.原地K-Ar定年是目前比样品返回更为实用的一种精确远程定年技术.黄钾铁矾(K... 详细信息

为了更好地确定火星不同地形所记录的气候变化的时间尺度,确定火星历史上重大事件的绝对年龄,并校准陨石坑率,需要从火星原地或从返回样品中获得精确的年龄数据.原地K-Ar定年是目前比样品返回更为实用的一种精确远程定年技术.黄钾铁矾(KFe_(3)(SO_(4))_(2)(OH)_(6)),是火星上广泛存在的唯一一种通过就位探测、轨道遥感探测、陨石研究三种手段都确定存在的含钾硫酸盐矿物,它已被用于K-Ar和^(40)Ar/^(39)Ar精确定年.火星上黄钾铁矾的保存提供了火星上含水过程的性质和持续时间的信息,不同年龄的黄钾铁矾能有效地解读火星历史上地表水流动时期及过渡到当前干旱气候之间的演变历史.本文总结了近年来火星上黄钾铁矾存在的区域、矿物学特征、在火星上的稳定性、原地K-Ar定年的研究现状、黄钾铁矾氩扩散动力学等,探讨了黄钾铁矾原地K-Ar定年的关键科学问题、火星采样返回需求、未来研究方向等.

关键词：火星黄钾铁矾原地K-Ar定年氩扩散稳定性

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Gas Exchange Rates of Texas Persimmon (diospyros texana) in Central Texas Woodlands

引用

American Journal of Plant Sciences 2024年第5期15卷 329-348页

作者： Matthew b. Grunstra Oscar W. Van Auken department of Integrative biology University of Texas at San Antonio San Antonio TX USA

diospyros texana (Texas persimmon) is a secondary species in most Juniperus ashei/Quercus fusiformis woodlands in central Texas. It has high density, but plants are mostly in the community understory. Light response curves at ambient and elevated levels of COb>2b> and temperature were measured for d. texana. The Ab>netb> (photosynthetic rate) increased significantly as both light level and COb>2b> levels increased but not temperature. The Ab>maxb> (maximum photosynthetic rate) of d. texana in full sun at elevated levels of COb>2b> was increased for all treatments. Stomatal conductance increased with levels of COb>2b> but only if the interaction was removed from the model. Intercellular levels of COb>2b> increased with both temperature and COb>2b> treatments as did water use efficiency (WUE). Furthermore, light saturation (Lb>satb>) increased with COb>2b> treatments and light compensation (Lb>cpb>) increased with temperature. The dark respiration (Rb>db>) increased with both temperature and COb>2b> treatments. Markov population models suggested d. texana populations would remain ecologically similar in the future. However, sub-canopy light levels and herbivory should be considered when examining population projections. For example, Juniperus ashei juveniles are not recruited into any canopy unless there are high light levels. Herbivory reduces the success of Quercus juveniles from reaching the canopy. These factors do not seem to be a problem for d. texana juveniles which would allow them to reach the canopy without need of a high light gap and are not prevented by herbivory. Thus, Juniperus/Quercus woodlands will change in the future to woodlands with d. texana a more common species.

关键词： Replacement dynamics Ecological Succession CO2 Concentrations Temperature Levels Photosynthetic Rates drought Tolerance Herbivory Species Replacement Encroachment Juniper

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

discovery of new MAX-phase-like layered ternary carbide V_(8)P_(6)C:Crystal structure,thermal expansion,and elastic properties

引用

Journal of Materials Science & Technology 2024年第7期174卷 55-62页

作者： H.X.Chen L.Sheng Z.L.Zhang X.C.Wen d.L.Yang X.Y.Ye P.Q.dai School of Materials Science and Engineering Fujian University of TechnologyFuzhou 350118China beijing Synchrotron Radiation Facility Institute of High Energy PhysicsChinese Academy of ScienceBeijing 100049China Fujian Provincial Key Laboratory of Advanced Materials Processing and Application Fuzhou 350118China State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China

due to the laminated structure,MAX phases and MAX-phase-like compounds possess outstanding dam-age tolerance capability with good thermal/electrical conductivity and other charming functional prop-erties,showing a bright future for structural-functional ***,a new MAX-phase-like ternary car-bide V_(8)P_(6)C with layered characteristics was *** to the alternate stacking of hexagonal-arranged M/A/X atom layers in MAX phases,V_(8)P_(6)C has a layered structure formed by a repeated stacking of the slabs consisting of V_(6)C-octahedrons and VP 6-distorted-octahedrons in three-atomic layers *** thermal expansion anisotropy was revealed,with the thermal expansion coefficients(TECs)along a-axis,c-axis,and the average value,equal toα_(a)=8.55(5)μK^(−1),α_(c)=10.23(5)μK^(−1),andα_(L)=9.14(5)μK^(−1),*** dilation along the c-axis was mainly dominated by out-plane V-P bonds be-tween layered *** to the pressure-dependent lattice parameters,the polycrystalline bulk modulus(b_(0)=185(9)GPa)and high compressibility anisotropy factor(b_(a)/b_(c)=1.64)was ***-while,the second-order elastic constants were calculated,and the elastic moduli,E=303 GPa,b=198 GPa,G=122 GPa,andν=0.246,were *** the weak connection between layer slabs by out-plane V1-P bond was revealed by the bond stiffness model,with a bond stiffness close to the M-A bond in MAX ***,good damage tolerance capability was predicted according to Paugh’s ratio(G/b=0.616)and Cauchy pressure(P_(a)=0 GPa,P_(c)=-7.5 GPa),even better than those of typical MAX *** discovery of V_(8)P_(6)C provides a new member of MAX-phase-like damage-tolerant ceramic with relatively low density,moderate thermal expansion,and anisotropic compressibility,and the unique lay-ered structure is inspiring for exploring new layered ternary ceramics.

关键词： New ternary carbide MAX phase Thermal expansion Elastic constants Anisotropy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advanced analytical determination of volatile organic compounds (VOC) and other major contaminants in water samples using GC-Ion Trap MS

引用

Journal of Environmental Sciences 2001年第1期13卷 25-36页

作者： b M Koroma K X Wang d d Jinya Laboratory of Socioeconomic Science of Food Production Nagoya University Japan.

The GC-Ion Trap MS is recently one of the most efficient instrumental analysis recommended for understanding the chemistry of volatile organic compounds, not only in water but even in the food chain and other environmental media (air and soil). Results of the experiment conducted on water samples from Kuguri and Yatsutani sampling stations showed considerably higher levels of organic enrichment (COd = 10 mg/L and 11 mg/L respectively). Total concentrations of Pb (0.072 mg/L and 0.093 mg/L) and Cd (0.004 mg/L and 0.011 mg/L) on the other hand, invariably exceeded the maximum allowable concentrations for human health and the living environment (Pb = 0.005 mg/L; Cd = 0.001 mg/L respectively). And the toxicity levels for these contaminants at LC50 showed critical impact on rainbow trout (hypersensitive species) at 0.14 mg/L for Pb and 0.007 mg/L for Cd in 96 hours respectively. Although these major contaminants including phenol and 3-, 4-cresol, showed relatively higher toxicity impact in the experimental media, it would remain contentious to justify any associated potential dangers without regular routine water monitoring, at least for a period of one year. Nevertheless, the data could serve as a benchmark through which other phenomena can easily be investigated.

关键词： www Advanced analytical determination of volatile organic compounds and other major contaminants in water samples using GC-Ion Trap MS VOC Eb GC

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Electron kinetic effects in back-stimulated Raman scattering bursts driven by broadband laser pulses

引用

Matter and Radiation at Extremes 2024年第4期9卷 54-67页

作者： Q.K.Liu L.deng Q.Wang X.Zhang F.Q.Meng Y.P.Wang Y.Q.Gao H.b.Cai S.P.Zhu Graduate School China Academy of Engineering PhysicsBeijing 100088China Institute of Applied Physics and Computational Mathematics Beijing 100094China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230026China Shanghai Institute of Laser Plasma Shanghai 201800China HEdPS Center for Applied Physics and TechnologyPeking UniversityBeijing 100871China School of Physics Zhejiang UniversityHangzhou 310027China

We examine electron kinetic effects in broadband-laser-driven back-stimulated Raman scattering(bSRS)bursts using particle-in-cell *** bursts occur during the nonlinear stage,causing reflectivity spikes and generating large numbers of hot ***-duration simulations are performed to observe burst events,and a simplified model is developed to eliminate the interference of the broadband laser’s random intensity *** the simplified model,we isolate and characterize the spectrum of electron plasma *** spectrum changes from a sideband structure to a turbulence-like structure during the burst.A significant asymmetry in the spectrum is *** asymmetry is amplified and transferred to electron phase space by high-intensity broadband laser pulses,leading to violent vortex-merging and generation of hot *** proportion of hot electrons increases from 6.76%to 14.7%during a single violent burst *** demonstrate that kinetic effects profoundly influence the bSRS evolution driven by broadband lasers.

关键词： scattering kinetic simplified

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：