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向丙泊酚麻醉患者血管内注射含肾上腺素的硬膜外试验剂量观察灌注指数的预测效能

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麻醉与镇痛 2010年第4期6卷 53-57页

作者： Hany A. Mowafi salah A. Ismail Mohammed A. shaft AbdulMohsin A. Al-Ghamdi 谢珺田(译) 宋文阁(校) Department of Anesthesiology Faculty of Medicine King Faisal University Saudi Arabia 不详

背景灌注指数是一种无创性的来自干血氧饱和度监测的反映外周循环灌注的指标。本研究评估了灌注指数做为探索成人丙泊酚麻醉过程中血管内注入包含15μg肾上腺素的硬膜外试验剂量药物后变化指标的有效性；同时将它与常规评估标准-心率（H... 详细信息

背景灌注指数是一种无创性的来自干血氧饱和度监测的反映外周循环灌注的指标。本研究评估了灌注指数做为探索成人丙泊酚麻醉过程中血管内注入包含15μg肾上腺素的硬膜外试验剂量药物后变化指标的有效性；同时将它与常规评估标准-心率（HR）（如果升高≥10bpm则为阳性）及收缩压（sBP）（如果升高≥15mmHg则为阳性）进行了可靠性比较。方法40例全静脉麻醉、择期行普外科手术的患者随机静脉注射3ml含5μg/ml肾上腺素浓度为15mg／ml的利多卡因或3ml生理盐水（每组n=20）。监测注射后5分钟的心率、收缩压和灌注指数（PI）。结果注射试验剂量在39±15秒后平均最大灌注指数降低65％±13％。心率和血压的最大增量分别为49±25秒后19±8bpm和102±34秒后17±7mmHg。用灌注指数作为血管内注射的评估指标（如果灌注指数较注射前降低≥10％则为阳性），其敏感性、特异性、阳性预期值和阴性预期值是100％（95％可信区间CI=83％-100％）。相对地，心率和血压指标的敏感性分别为95％（CI=76％-99％）和90％（CI=70％-97％）。结论灌注指数是评价成年丙泊酚静脉麻醉患者血管内注射硬膜外试验剂量药物后常规血流动力学变化的可靠的选用指标。

关键词：肾上腺素浓度血管内注射试验剂量麻醉过程硬膜外丙泊酚灌注患者

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埃及尼罗河三角洲城市化监测

AMBIO－人类环境杂志 1999年第7期28卷 627-631页

作者： Mohamed sultan Michael Fiske Thomas stein Mohamed Gamal Yehia Abdel Hady Hesham el Araby Ahmed Madani salah Mehanee Richard Becker 石培礼阿尔贡国家实验室华盛顿大学地球与行星科学系开罗大学中国科学院地理科学与资源研究所

对1972、1984和1990年在尼罗河三角洲获取的Landsat Mss和TM影象(scenes)处理的和协同配准的(coregistered)数字镶嵌图比较表明,城镇增长正危及着埃及农业的生产力。在1972、1984和1990年尼罗河三角洲的城镇面积至少分别占3.6%、4.7%和5... 详细信息

对1972、1984和1990年在尼罗河三角洲获取的Landsat Mss和TM影象(scenes)处理的和协同配准的(coregistered)数字镶嵌图比较表明,城镇增长正危及着埃及农业的生产力。在1972、1984和1990年尼罗河三角洲的城镇面积至少分别占3.6%、4.7%和5.7%,在这18年期间增长了58%。大约一半的增长出现在1984～1990年期间。如果这种趋势继续下去,到2010年埃及将因城市化而丧失农地总面积的12%。尽管事实上城镇增长主要出现在城市周围,但在几千个小村庄周围的增长却对尼罗河三角洲的农业生产构成最大的威胁。1972～1990年间,城市和大村庄的累积增长率为37%,而同期小村庄的累积增长率为77%。

关键词：尼罗河三角洲城市化监测埃及农业生产力

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使用可回缩隆突钩放置双腔气管导管：一项前瞻性研究报告

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麻醉与镇痛 2011年第3期7卷 97-100页

作者： Roshdi R. Al-Metwalli MBBch, Msc, MD Hany A. Mowafi, MBBch, Msc, MD salah A. Ismail, MBBch, Msc, MD 姚凤珍(译) Department of Anesthesiology Faculty of Medicine King Faisal University Saudi Arabia 不详

背景双腔气管导管（DLT）的准确放置对于其最佳功能的发挥至关重要。我们利用可回缩隆突钩对标准的左侧DLT盲置法进行改良。本研究旨在明确这种改良法与传统方法相比，是否能够提高首次插管精确定位的成功率。方法对40例拟行左侧DLT的... 详细信息

背景双腔气管导管（DLT）的准确放置对于其最佳功能的发挥至关重要。我们利用可回缩隆突钩对标准的左侧DLT盲置法进行改良。本研究旨在明确这种改良法与传统方法相比，是否能够提高首次插管精确定位的成功率。方法对40例拟行左侧DLT的择期全麻手术患者进行了前瞻性随机对照研究。记录使用传统方法（传统方法组，n=20）或者改良法（隆突钩组，n=20）出现位置不正的发生率以及最终放置正确所需要的时间。可回缩隆突钩是经过改良的橡胶弹性探条。采用纤维支气管镜（FOB）证实导管放置位置正确。结果首次放置DLT后，单纯的临床评估发现传统方法组与隆突钩组分别有3例（共20例，15％）和1例（共20例，5％）导管位置不正。随后FOB发现隆突钩组导管位置不正的概率（20例中出现2例，10％）显著低于传统方法组（20例中出现9例，45％）（P=0．03）。两组首次放置DLTs的时间相似（P=0．63），而FOB确认与调整所需的时间在隆突钩组（88．9±35．7秒）显著短于传统方法组（152．3±40．3秒）（P〈0．0001）。结论可回缩隆突钩的使用提高了DLT准确放置的成功率并且缩短了DLT位置调整时间。此外，该方法的安全性与可靠性仍需更大量的研究进行证实。

关键词：双腔气管导管放置位置隆突钩回缩前瞻性随机对照研究择期全麻手术纤维支气管镜导管位置

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钢纤维加固混凝土

钢结构(中英文) 2010年第9期 86-86页

作者： samer A.Barakat salah Altoubat

以钢纤维为焊接材料连接两梁,研究延长后梁的耐久性。给出了16根大面积粘贴钢纤维的简支梁和4根普通简支梁三点受荷的试验结果。这16根梁共用了36根(截面尺寸:200mm×220mm,长度1000mm)等截面混凝土构件。选用的试验参数为节点的类型、... 详细信息

以钢纤维为焊接材料连接两梁,研究延长后梁的耐久性。给出了16根大面积粘贴钢纤维的简支梁和4根普通简支梁三点受荷的试验结果。这16根梁共用了36根(截面尺寸:200mm×220mm,长度1000mm)等截面混凝土构件。选用的试验参数为节点的类型、梁分段的长度和段数及钢纤维的体积率。试验中采用了3种节点长度(100,200,300mm),2种钢纤维的体积率(2%和3%)。记录了梁的荷载-挠度曲线、开裂和破坏特征及抗弯承载力。结果表明,节点长度300mm且钢纤维体积率为2%的梁的抗弯性能与对照梁接近。说明钢纤维加固混凝土技术在保证梁抗弯能力的同时,也满足耐久性的要求。

关键词：混凝土焊接钢纤维片预制构件梁

Relationship between the Polymorphism of the GsTP1 (rs1695) Gene and Chronic Hepatitis B Infection in Ouagadougou, Burkina Faso

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Journal of Biosciences and Medicines 2023年第11期11卷 94-107页

作者： Tilate Lare Lassina Traore Marie simone Traore sidnooma Véronique Zongo Pierre Zabre Mousso savadogo Fortune D. salah Herman Karim sombie Pegdwendé Abel sorgho Tégwindé Rebeca Compaore Tani sagna Issoufou Tao Florencia Wendkuuni Djigma Dorcas Obiri-Yeboah Damintoti simplice Karou Rogomenoma Alice Ouedraogo Teega-Wende Clarisse Ouedraogo Prosper Bado Albert Théophane Yonli Jacques simpore Laboratoire de Biologie Moléculaire et de Génétique Université Joseph KI-ZERBO Ouagadougou Burkina Faso ecole Normale supérieure Ouagadougou Burkina Faso Laboratoire de Biologie Moléculaire-Virologie Institut National d’Hygiène Lomé Togo Centre de Recherche Biomoléculaire Pietro Annigoni (CeRBA) Ouagadougou Burkina Faso Centre National de la Recherche scientifique et Technologique Institut de Recherche en Sciences de la Santé Ouagadougou Burkina Faso Institut des sciences et de Technologies/ecole Normale supérieure Koudougou Burkina Faso Department of Microbiology and Immunology School of Medical Sciences University of Cape Coast PMB Cape Coast Ghana école supérieure des Techniques Biologiques et Alimentaires Université de Lomé (ESTBA-UL) Lomé Togo Centre Universitaire de Gaoua Université Nazi Boni Bobo-Dioulasso Burkina Faso

Introduction: Genetic polymorphisms of some Glutathione s-Transferase (GsT) which encode the enzyme responsible for the biotransformation of drugs and xenobiotics, have been associated with the risk of several pathologies that can progress to cancer such as Hepatitis B. This study aims to characterize the impact of the rs1695 polymorphism of GsTP1 gene among people with chronic Hepatitis B infection in Burkina Faso. Methods: rs1695 polymorphisms of GsTP1 gene genotyping was performed for 50 people infected with chronic Hepatitis B virus and 124 healthy people with the PCR-RFLP method. Conventional PCR was used for DNA amplification and Alw26I enzyme was used for enzymatic digestion. Results: The results show that the frequencies of AA, AG and GG genotypes are respectively 31.00%, 36.80% and 32.20% in general the study population with a mutation rate of 50.57%. However, the incidence of the AA, AG and GG genotypes are respectively 30.64%, 38.71% and 30.64% among people with chronic Hepatitis B virus infection and 32.00%, 32.00% and 36.00% among healthy people. In cases, the frequencies of the A and G alleles are 48.00% and 52.00% respectively, and in controls 50.00% each. No statistical difference was found by comparing genotypic and allelic frequencies between cases and controls (p > 0.05). Conclusion: Our study allowed us to determine the rate of GsTP1 rs1695 genotypes in the study population, cases and controls. From our analyses, GsTP1 rs1695 is not associated to chronic Hepatitis B virus infection in Ouagadougou.

关键词： Polymorphism GsTP1 Chronic Hepatitis B Healthy People Burkina Faso

endoscopic management of Dieulafoy's lesion using Isoamyl-2-cyanoacrylate

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World Journal of Gastrointestinal endoscopy 2013年第8期5卷 417-419页

作者： Abd elrazek M Aly Abd elrazek Nakamura Yoko Moriguchi Hiroki Mohamed Afify Mohamed Asar Badr Ismael Magdy salah Medicine of Liver Transplantation Department of Tropical Medicine Faculty of Medicine Al Azhar University Department of General surgery and endoscopy Faculty of Medicine Al Azhar University Department of Medical Informatics Institute of Biomedical Science-University of Tokushima Department of Anesthesia and Intensive Care Al Azhar University

Dieulafoy's lesion (DL) is a rare but important cause of obscure gastrointestinal ble.ding that may be over-looked during diagnostic endoscopy. Mortality rates are similar to those of other causes for gastrointestinal ble.ding. Diagnosis by upper endoscopy is the modal-ity of choice during acute ble.ding. In the absence of active ble.ding, the lesion resembles a raised nipple or visible vessel. There are no guidelines regarding effective selective therapy for DL, when diagnosed, en-doscopist experience is the major determinant of the treatment strategy. Following our strategy, an expert endoscopist with a skilled assistant should have a high rate of successful DL diagnosis when an obscured gas-trointestinal lesion is suspected. Cyanoacryltes com-pounds have been used successfully in management of Gastric varices and DLs. To our knowledge, there have been no previous reports regarding use of isoamyl-2-cyanoacrylate (AMCRYLATe ; Concord Drugs Ltd.,Hyderabad, India) as an effective therapy for gastric DL without serious complications. In our case study, Isoamyl-2-cyanoacrylate (AMCRYLATe) was effective and safe for treating DL. surgical wedge resection of the lesion should be considered as a therapeutic option if endoscopic therapy fails.

关键词： Dieulafoy’s lesion Isoamyl-2-cyanoacrylate Gastrointestinal ble.ding endoscopy stomach

儿童自体干细胞移植第1年内的移植后感染并发症

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世界核心医学期刊文摘（儿科学分册） 2005年第10期1卷 36-36页

作者： Ben salah H. Coze C. Gentet J.C. 郭战宏 Centre Apollo-mêdical 8 R. Apollo-11 cite Mahrajene 1082 Tunis Tunisia

Background.-studies on the infectious complications postengrafment in pediatr ic stem cell transplantation patients are rare. The aim of this study was to ass ess the incidence, types, outcome and factors affecting late infections. Patient s and methods. -A single-institution retrospective analysis was done of infect ions recorded in the first year following engrafment in children who underwent a utologous stem cell transplantation for solid tumors from January 1991 to Decemb er 2000. A systematic antimicrobial chemoprophylaxis of TMP/sMX was administered . Patients who were at high risk for varicellazona virus infection received prop hylactic acyclovir. Results. -eighty-four assessable patients were enrolled. F ifty-four patients (64%) underwent autologous peripheral blood stem cell trans plantation and 30 patients (36%) underwent bone marrow transplantation. Forty- nine episodes of infections were documented in 39 patients(46%) of whom 27 pati ents (32%) developed infections after the first 100 days post transplantation. Bacterial septicemia occurred in nine patients of whom four patients had a cathe ter-related septicemia. Twelve patients (14%) developed localized herpes zoste r infection. Local fungal infection occurred in five patients. Infection-relate d death occurred in one patient with non-documented pneumonitis. Univariable an alysis showed a correlation between the CD34+cell dose e de velopment of infections (P =0.04). Patients who did not go into remission after transplantation where at high risk for septicemia (P =0.007)-. Multivariate ana lysis showed that a history of varicella or pretransplant varicella-zona positi vity was the only significant factor for development zoster infection (P =0.01). Conclusion. -Our study shows that infections in the first year postengrafment following autologous stem cell transplantation for solid tumors have a good prog nosis and that the use of TMP/sMX should be the single systematic antimicrobial pr

关键词：自体干细胞移植感染并发症实性肿瘤无环鸟苷带状疱疹脓毒症水痘病单中心预后良好骨髓移植

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