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Optical coherence tomography angiography metrics in different stages of diabetic macular edema

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Eye and Vision 2024年第3期10卷 13-20页

作者： Ruyi Han Ruowen gong Wei Liu Gezhi Xu Eye Institute and Department of Ophthalmology Eye and ENT Hospital of Fudan University83 Fenyang RoadShanghai200031People’s Republic of China Key Laboratory of Visual Impairment and Restoration Fudan UniversityShanghaiPeople’s Republic of China Key Laboratory of Myopia(Fudan University) Chinese Academy of Medical SciencesNational Health CommissionShanghaiPeople’s Republic of China

Background To investigate the optical coherence tomography angiography(OCTA)characteristics of diabetic macular edema(DME)at different *** This study was a cross-sectional *** diagnosed with DME were *** was classified into early,advanced,and severe *** vessel density(VD)in the superficial vascular plexus(SVP),deep vascular plexus(DVP)and foveal avascular zone(FAZ)parameters,including FAZ area,FAZ perimeter,acircularity index and foveal VD in a 300-μm-wide region around the FAZ(FD-300),were calculated by the AngioVue software.A multivariate generalized estimating equation was used to evaluate the associations between visual acuity and OCTA *** Ninety-two eyes from 74 patients with DME were included in this *** to early(P=0.006)and advanced DME(P=0.003),the acircularity index was higher in severe *** whole and parafoveal VD in the DVP decreased in eyes with severe DME compared to early DME(P=0.018,P=0.005,respectively)and advanced DME(P=0.035,P=0.012,respectively).In the multivariate generalized estimating equation,DME severity,FAZ area and foveal thickness were positively associated with worse visual acuity(P=0.001,P=0.007 and P=0.001,respectively).Conclusion Compared to early and advanced DME,severe DME showed increased irregularity in the FAZ and more extensive vessel damage in the *** severity level of DME,larger FAZ area,and increased foveal thickness could be risk factors for poor visual *** registration The protocol was published in the Chinese Clinical Trial Registry(ChiCTR2000033082).

关键词： Optical coherence tomography angiography Diabetic macular edema Vessel density Acircularity index

Room-temperature ferroelectricity in van der Waals SnP_(2)S_(6)

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Frontiers of physics 2024年第4期19卷 113-123页

作者： Chaowei He Jiantian Zhang Li gong Peng Yu State Key Laboratory of Optoelectronic Materials and Technologies Guangzhou Key Laboratory of Flexible Electronic Materials and Wearable Devices Nanotechnology Research Center School of Materials Science and EngineeringSun Yat-sen UniversityGuangzhou 510275China Instrumental Analysis and Research Center Sun Yat-sen UniversityGuangzhou 510275China

Two-dimensional(2D)ferroelectric materials,which possess electrically switchable spontaneous polarization and can be easily integrated with semiconductor technologies,is of utmost importance in the advancement of high-integration low-power *** the experimental discovery of certain 2D ferroelectric materials such as CuInP2S6 and In2Se3,achieving stable ferroelectricity at room temperature in these materials continues to present a significant ***,stable ferroelectric order at room temperature in the 2D limit is demonstrated in van der Waals SnP_(2)S_(6) atom layers,which can be fabricated via mechanical exfoliation of bulk SnP_(2)S_(6) *** polarization is observed in thin SnP_(2)S_(6) of~7 ***,a van der Waals ferroelectric field-effect transistor(Fe-FET)with ferroelectric SnP_(2)S_(6) as top-gate insulator and ptype WTe0.6Se1.4 as the channel was designed and fabricated successfully,which exhibits a clear clockwise hysteresis loop in transfer characteristics,demonstrating ferroelectric properties of SnP_(2)S_(6) atomic *** addition,a multilayer graphene/SnP_(2)S_(6)/multilayer graphene van der Waals vertical heterostructure phototransistor was also fabricated successfully,exhibiting improved optoelectronic performances with a responsivity(R)of 2.9 A/W and a detectivity(D)of 1.4×10^(12) *** results show that SnP_(2)S_(6) is a promising 2D ferroelectric material for ferroelectric-integrated low-power 2D devices.

关键词： two-dimensional ferroelectric materials ferroelectric fieldeffect transistors photodetectors

Fast fixed-time three-dimensional terminal guidance with non-concave trajectory constraint

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Chinese Journal of Aeronautics 2024年第3期37卷 208-218页

作者： Youmin gong Yanning GUO Yueyong LYU Dongyu LI Guangfu MA Department of Control Science and Engineering Harbin Institute of TechnologyHarbin 150001China School of Cyber Science and Technology Beihang UniversityBeijing 100191China

Focusing on the non-concave trajectory constraint,a sliding-mode-based nonsingular feedback fast fixed-time three-dimensional terminal guidance of rotor unmanned aerial vehicle landing,planetary landing and spacecraft rendezvous and docking terminal phase with external disturbance is investigated in this ***,a fixed-time observer based on real-time differentiator is developed to compensate for the external disturbance,whose estimation error can converge to zero after a time independent of the initial ***,a sliding surface ensuring fixed-time convergence is *** sliding surface can guarantee that the vehicle achieves a non-concave trajectory,which is better for avoiding collision and maintaining the visibility of the landing site or docking ***,the nonsingular guidance ensuring the fixed-time convergence of the sliding surface is proposed,which is continuous and chatter *** last,three numerical simulations of Mars landing are performed to validate the effectiveness and correctness of the designed scheme.

关键词： Three-dimensional Terminal guidance Non-concave trajectory constraint Fast fixed-time control Sliding mode control

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Freeze-induced acceleration of iodide oxidation and consequent iodination of dissolved organic matter to form organoiodine compounds

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Journal of Environmental Sciences 2024年第10期144卷 67-75页

作者： Xuexin gong Mei He Zhineng Hao Rusong Zhao Jingfu Liu School of Resources and Environment Yangtze UniversityWuhan 430100China State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China Qilu University of Technology(Shandong Academy of Sciences) Shandong Analysis and Test CenterKey Laboratory for Applied Technology of Sophisticated Analytical Instruments of Shandong ProvinceJinan 250014China Institute of Environment and Health Jianghan UniversityWuhan 430056China

Freeze-induced acceleration of I–oxidation and the consequent iodination of dissolved organic matter(DOM)contribute to the formation of organoiodine compounds(OICs)in cold *** formed OICs may be a potentially important source of risk and are very closely with the environment and human ***,we investigated the acceleration effects of the freeze process on I–oxidation and the formation of *** comparison to reactive iodine species(RIS)formed in aqueous solutions,I–oxidation and RIS formation were greatly enhanced in frozen solution and were affected by pH,and the content of I–and ***-thaw process further promoted I–oxidation and the concentration of RIS reached 45.7μmol/L after 6 freeze-thaw *** consequent products of DOM iodination were greatly promoted in terms of both concentration and *** total content of OICs ranged from 0.02 to 2.83μmol/L under various *** 183–1197 OICs were detected by Fourier transform ion cyclotron resonance mass spectrometry,and more than 96.2%contained one or two iodine *** OICs had aromatic structures and were formed via substitution and addition *** findings reveal an important formation pathway for OICs and shed light on the biogeochemical cycling of iodine in the natural aquatic environment.

关键词： Freeze process Dissolved organic matter(DOM) Iodination Organoiodine compounds(OICs) Ultrahigh resolution mass spectrometry

From tunnel boring machine to tunnel boring robot: perspectives on intelligent shield machine and its smart operation

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2024年第5期25卷 357-381页

作者： Yakun ZHANG Guofang gong Huayong YANG Jianbin LI Liujie JING State Key Laboratory of Fluid Power and Mechatronic Systems Zhejiang UniversityHangzhou 310058China China Railway Engineering Equipment Group Co. Lid.Zhengzhou 450016China Maha Fluid Power Research Center Purdue UniversityWest LafayetteIN 47905USA

Advances in intelligent shield machines reflect an evolving trend from traditional tunnel boring machines(TBMs)to tunnel boring robots(TBRs).This shift aims to address the challenges encountered by the conventional shield machine industry arising from construction environment and manual *** study presents a systematic review of intelligent shield machine technology,with a particular emphasis on its smart ***,the definition,meaning,contents,and development modes of intelligent shield machines are *** development status of the intelligent shield machine and its smart operation are then *** analyzing the operation process of the shield machine,an autonomous operation framework considering both stand-alone and fleet levels is *** and recommendations are given for achieving autonomous *** study offers insights into the essence and developmental framework of intelligent shield machines to propel the advancement of this technology.

关键词： Intelligent shield machine Tunnel boring machine(TBM) Tunnel boring robot(TBR) Self-driving Autonomous control Shield machine

Therapeutic advances in atrial fibrillation based on animal models

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2024年第2期25卷 135-152页

作者： Qian gong Xuan LE Pengcheng YU Lenan ZHUANG Institute of Genetics and Reproduction College of Animal SciencesZhejiang UniversityHangzhou310058China Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang Province Department of CardiologySir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou310016China

Atrial fibrillation(AF)is the most prevalent sustained cardiac arrhythmia among humans,with its incidence increasing significantly with *** the high frequency of AF in clinical practice,its etiology and management remain *** develop effective treatment strategies,it is imperative to comprehend the underlying mechanisms of AF;therefore,the establishment of animal models of AF is vital to explore its *** spontaneous AF is rare in most animal species,several large animal models,particularly those of pigs,dogs,and horses,have proven as invaluable in recent years in advancing our knowledge of AF pathogenesis and developing novel therapeutic *** review aims to provide a comprehensive discussion of various animal models of AF,with an emphasis on the unique features of each model and its utility in AF research and *** data summarized in this review provide valuable insights into the mechanisms of AF and can be used to evaluate the efficacy and safety of novel therapeutic interventions.

关键词： Atrial fibrillation Animal model Therapeutic

Implications of the Stellar Mass Density of High-z Massive Galaxies from JWST on Warm Dark Matter

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Research in Astronomy and Astrophysics 2024年第1期24卷 128-134页

作者： Hengjie Lin Yan gong Bin Yue Xuelei Chen National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Science Center for China Space Station Telescope National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China Department of Physics College of SciencesNortheastern UniversityShenyang 110819China Center for High Energy Physics Peking UniversityBeijing 100871China

A significant excess of the stellar mass density at high redshift has been discovered from the early data release of James Webb Space Telescope(JWST),and it may require a high star formation ***,this will lead to large number density of ionizing photons in the epoch of reionization(EoR),so that the reionization history will be changed,which can arise tension with the current EoR *** dark matter(WDM),via the free streaming effect,can suppress the formation of small-scale structure as well as low-mass *** provides an effective way to decrease the ionizing photons when considering a large star formation efficiency in high-z massive galaxies without altering the cosmic reionization *** the other hand,the constraints on the properties of WDM can be derived from the JWST *** this work,we study WDM as a possible solution to reconcile the JWST stellar mass density of high-z massive galaxies and reionization *** find that,the JWST high-z comoving cumulative stellar mass density alone has no significant preference for either CDM or WDM *** using the observational data of other stellar mass density measurements and reionization history,we obtain that the WDM particle mass with mw=0.51_(-0.12)^(+0.22) keV and star formation efficiency parameter f_(*)^(0)> 0.39 in 2σ confidence level can match both the JWST high-z comoving cumulative stellar mass density and the reionization history.

关键词： Cosmology (cosmology:)dark matter (cosmology:)large-scale structure of universe

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Strategies of selective electroreduction of aqueous nitrate to N_(2) in chloride-free system:A critical review

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Green Energy & Environment 2024年第2期9卷 198-216页

作者： Fukuan Li Weizhe Zhang Peng Zhang Ao gong Kexun Li College of Environmental Science and Engineering Nankai UniversityTianjin300350China MOE Key Laboratory of Pollution Processes and Environmental Criteria Tianjin Key Laboratory of Environmental Remediation and Pollution ControlTianjin Key Laboratory of Environmental Technology for Complex Trans-Media PollutionNankai UniversityTianjin300350China

Electroreduction of nitrate has been gaining wide attention in recent years owing to it's beneficial for converting nitrate into benign N_(2) from the perspective of electrocatalytic denitrification or into value-added ammonia from the perspective of electrocatalytic NH_(3) *** reason of the undesired formation of ammonia is dominant during electroreduction of nitrate-containing wastewater,chloride has been widely used to improve N_(2) ***,selective electroreduction of nitrate to N2 gas in chloride-containing system poses several *** this review,we focus on the key strategies for efficiently enhancing N_(2) selectivity of electroreduction of nitrate in chloride-free system,including optimal selection of elements,combining an active metal catalyst with another metal,manipulating the crystalline morphology and facet orientation,constructing core–shell structure catalysts,*** summarizing the strategies,four possible reaction pathways of electro-reduction of nitrate to N_(2) are ***,this review attempts to provide practical strategies for enhancing N2 selectivity without the aid of electrochlorination and highlight directions for future research for designing appropriate electrocatalyst for final electrocatalytic denitrifi-cation.

关键词： Nitrate Chloride Electroreduction Selectivity Nitrogen

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Beamforming design for covert broadcast communication with hidden adversary

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Science China(Information Sciences) 2024年第6期67卷 384-398页

作者： Weiyu CHEN Haiyang DING Shilian WANG Junshan LUO Fengkui gong College of Electronic Science and Technology National University of Defense Technology College of Information and Communication National University of Defense Technology State Key Laboratory of Integrated Service Networks Xidian University

This paper explores covert broadcast communication in a challenging situation in which the transmitter, Alice, faces uncertainty regarding the position of the passive adversary, Willie. In this situation,controlling the signal exposure becomes difficult. Specifically, this paper focuses on the cases where Alice can delimit the suspicious areas where Willie may be located. The suspicious areas can have arbitrary number and shapes. Under the Rician fading model, the analytical expression of Willie's detection performance is derived. Then, the transmit power, the beamforming direction, and the number of channel uses are jointly designed to minimize the optimal Willie's detection performance among all the possible positions of Willie, on the premise of satisfying receivers' quality-of-service requirements. To tackle the formulated knotty problem with an infinite number of irregular and discontinuous Willie's possible positions, the continuous nature of the antenna pattern is exploited to convert the original problem into the one with a finite number of possible positions, by sampling the suspicious areas. Then, different algorithms are developed to address the resultant non-convex optimization problem for single-antenna Willie and multi-antenna Willie, respectively. Numerical results demonstrate significant performance gains of the proposed scheme over the widely-adopted maximum ratio transmission scheme, which indicates that simply adjusting the main lobe towards the receiver is indeed far away from optimum and shows the importance of leveraging Alice's limited knowledge of Willie's position.

关键词： low-probability-of-detection communication multiple antennas covertness performance uncertain position parameters optimization