Occult hepatitis B virus(HBV)infection,by definition,is a state in which infection with this virus does not manifest with the conventional diagnostic laboratory criteria reserved for the obvious form of HBV *** a resu...
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Occult hepatitis B virus(HBV)infection,by definition,is a state in which infection with this virus does not manifest with the conventional diagnostic laboratory criteria reserved for the obvious form of HBV *** a result,occult HBV infection is commonly a surprise finding discovered accidently during the evaluation of other apparent liver diseases,such as hepatitis C virus(HCV)infection or non-alcoholic fatty liver disease and,more importantly,their evolution into life-threatening hepatocellular *** infection with HCV and occult HBV is rarely considered when assessing these more obvious conditions,and in an attempt to offer a better understanding of this phenomenon,this study attempted to shed some light onto the uniqueness of occult HBV infection by addressing the natural history of HBV and HCV infections,as well as non-alcoholic fatty liver *** was carried out by taking into account the exclusive integration process undertaken by the HBV genome into infected host hepatocytes,with consideration given to conditions which afford reactivation of the occult infection and stress on the molecular mechanisms that underlie occult HBV ***,the clinical outcome of occult HBV infection and its relation to hepatocellular carcinoma is analyzed.
Background:The availability of various types of COVID-19 vaccines and diverse characteristics of the vaccines pre‑sent a dilemma in vaccination choices,which may result in individuals refusing a particular COVID-19 va...
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Background:The availability of various types of COVID-19 vaccines and diverse characteristics of the vaccines pre‑sent a dilemma in vaccination choices,which may result in individuals refusing a particular COVID-19 vaccine ofered,hence presenting a threat to immunisation coverage and reaching herd *** study aimed to assess global COVID-19 vaccination intention,vaccine characteristics infuencing vaccination acceptance and desirable vaccine characteristics infuencing the choice of ***:An anonymous cross-sectional survey was conducted between 4 January and 5 March 2021 in 17 coun‑tries *** and the corresponding 95%confdence intervals(CI)of COVID-19 vaccine acceptance and vaccine characteristics infuencing vaccination acceptance were generated and compared across countries and *** logistic regression analysis was used to determine the factors associated with COVID-19 vaccine ***:Of the 19,714 responses received,90.4%(95%CI 81.8–95.3)reported likely or extremely likely to receive COVID-19 vaccine.A high proportion of likely or extremely likely to receive the COVID-19 vaccine was reported in Australia(96.4%),China(95.3%)and Norway(95.3%),while a high proportion reported being unlikely or extremely unlikely to receive the vaccine in Japan(34.6%),the U.S.(29.4%)and Iran(27.9%).Males,those with a lower educational level and those of older age expressed a higher level of COVID-19 vaccine *** than two-thirds(59.7%;95%CI 58.4–61.0)reported only being willing to accept a vaccine with an efectiveness of more than 90%,and 74.5%(95%CI 73.4–75.5)said they would accept a COVID-19 vaccine with minor adverse reactions.A total of 21.0%(95%CI 20.0–22.0)reported not accepting an mRNA vaccine and 51.8%(95%CI 50.3–53.1)reported that they would only accept a COVID-19 vaccine from a specifc country‐of‐*** from the Southeast Asia region reported the highest proportion of not accepting mRNA technolog
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