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经济增长目标管理对城市土地绿色利用效率的影响——基于282个地级及以上城市的经验证据

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中国土地科学 2024年第4期38卷 54-64页

作者：边志强山西财经大学资源型经济转型发展研究院山西太原030006

研究目的:利用2006—2021年全国282个地级及以上城市的面板数据,系统考察经济增长目标管理对城市土地绿色利用效率的影响。研究方法:超效率SBM模型,固定效应模型。研究结果:(1)经济增长目标对城市土地绿色利用效率呈现明显的负向影响效... 详细信息

研究目的:利用2006—2021年全国282个地级及以上城市的面板数据,系统考察经济增长目标管理对城市土地绿色利用效率的影响。研究方法:超效率SBM模型,固定效应模型。研究结果:(1)经济增长目标对城市土地绿色利用效率呈现明显的负向影响效应,且这一结论通过了克服内生性等一系列稳健性检验。(2)正式与非正式环境规制均能够减缓经济增长目标对城市土地绿色利用效率的负向影响,且后者的调节效应更强。(3)经济增长目标存在明显的自上而下逐级加码现象,且目标加码行为会对城市土地绿色利用效率产生抑制作用。(4)当目标约束程度为一般约束和硬约束,以及目标完成情况从未完成、正常完成到超额完成时,经济增长目标对城市土地绿色利用效率的负向影响显著且逐渐增强。研究结论:进一步淡化GDP增速在官员绩效考核中的重要性,尽量采用“留有余地”的软约束方式设定经济增长目标,重视环境规制的约束作用。

关键词：经济增长目标管理城市土地绿色利用效率环境规制目标加码目标约束

Exploration on the Teaching Reform of Criminal Investigation in Police College from the Perspective of Artificial Intelligence

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Exploration on the Teaching Reform of Criminal Investigation...

SMARTdb:An Integrated Database for Exploring Single-cell Multi-omics Data of Reproductive Medicine

2024社会发展与科技创新交流会

作者： Anqi Gu Hui bian Jiangsu Police College Rongcheng Certified Public Accountants

Under the new trend of digital investigation in the new era, the actual demand of public security forces public security higher education to introduce artificial intelligence technology for reform. From the perspective of teaching reform of criminal investigation with artificial intelligence, this study takes the course of Criminal Investigation as an example, relying on key technologies such as data mining, natural language processing, deep learning and virtual simulation, and constructs a brand-new teaching content, teaching mode, learning mode and teaching evaluation.

关键词： Artificial intelligence Major in public security criminal investigation Teaching reform

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Genomics, Proteomics & Bioinformatics 2024年第3期22卷 113-123页

作者： Zekai Liu Zhen Yuan Yunlei Guo Ruilin Wang Yusheng Guan Zhanglian Wang Yunan Chen Tianlu Wang Meining Jiang Shuhui bian State Key Laboratory of Reproductive Medicine and Offspring Health School of Public HealthNanjing Medical UniversityNanjing 211166China Collaborative Innovation Center for Cancer Personalized Medicine School of Public HealthNanjing Medical UniversityNanjing 211166China

Single-cell multi-omics sequencing has greatly accelerated reproductive research in recent years,and the data are continually ***,utilizing these data resources is challenging for wet-lab researchers.A comprehensive platform for exploring single-cell multi-omics data related to reproduction is urgently ***,we introduce the single-cell multi-omics atlas of reproduction(SMARTdb),an integrative and user-friendly platform for exploring molecular dynamics of reproductive development,aging,and disease,which covers multi-omics,multi-species,and multi-stage *** curated and analyzed single-cell transcriptomic and epigenomic data of over 2.0 million cells from 6 species across the entire lifespan.A series of powerful functionalities are provided,such as“Query gene expression”,“DIY expression plot”,“DNA methylation plot”,and“Epigenome browser”.With SMARTdb,we found that the male germ cell-specific expression pattern of RPL39L and RPL10L is conserved between human and other model ***,DNA hypomethylation and open chromatin may collectively regulate the specific expression pattern of RPL39L in both male and female germ *** summary,SMARTdb is a powerful platform for convenient data mining and gaining novel insights into reproductive development,aging,and *** is publicly available at https://***.

关键词： Database Single-cell multi-omics Embryo Germ cell Gonad

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高考招生综合评价的三种实现方式

江苏高教 2024年第8期 5-8页

作者：边新灿浙江师范大学教育学院浙江金华321019

高考招生综合评价可以从广义、狭义两个层面进行理解:广义的理解是高考改革的一项重要内容、一个改革方向;狭义的理解是目前我国部分省市和高校正在试点实施的一种特殊评价选拔模式,各省、校的名称有异,其共同的特征为多要素量化合成总... 详细信息

高考招生综合评价可以从广义、狭义两个层面进行理解:广义的理解是高考改革的一项重要内容、一个改革方向;狭义的理解是目前我国部分省市和高校正在试点实施的一种特殊评价选拔模式,各省、校的名称有异,其共同的特征为多要素量化合成总分录取。实行综合评价,是对“德智体全面考核择优录取”基本原则的贯彻落实,是高考制度完善长期探索的改革方向。2014年启动的新高考改革把综合评价作为高考招生改革的重要内容,在以往实践的基础上进一步探索形成了三种实现方式。

关键词：高考制度高考招生新高考改革全面考核综合评价择优录取试点实施部分省市

Lactate-mediated medium-chain fatty acid production from expired dairy and beverage waste

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Environmental Science and Ecotechnology 2024年第5期21卷 278-286页

作者： Bin bian Wenxiang Zhang Najiaowa Yu Wei Yang Jiajie Xu Bruce E.Logan Pascal E.saikaly Water Desalination and Reuse Center(WDRC) King Abdullah University of Science and Technology(KAUST)Thuwal 23955-6900Kingdom of Saudi Arabia Environmental Science and Engineering Program Biological and Environmental Science and Engineering(BESE)DivisionKing Abdullah University of Science and Technology(KAUST)Thuwal 23955-6900Kingdom of Saudi Arabia Department of Civil and Environmental Engineering The Pennsylvania State UniversityUniversity ParkPA16802USA Research Centre of Ecology&Environment for Coastal Area and Deep Sea Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou)Guangzhou511458China School of Marine Science Ningbo UniversityNingbo315211China

Fruits,vegetables,and dairy products are typically the primary sources of household food ***,anaerobic digestion is the most used bioprocess for the treatment of food waste with concomitant generation of ***,to achieve a circular carbon economy,the organics in food waste should be converted to new chemicals with higher value than *** we demonstrate the feasibility of medium-chain carboxylic acid(MCCA)production from expired dairy and beverage waste via a chain elongation platform mediated by *** a two-stage fermentation process,the first stage with optimized operational conditions,including varying temperatures and organic loading rates,transformed expired dairy and beverage waste into lactate at a concentration higher than 900 mM C at 43℃.This lactate was then used to produce>500 mM C caproate and>300 mM C butyrate via microbial chain ***,lactate-producing microbes such as Lactobacillus and Lacticaseibacillus were regulated by temperature and could be highly enriched under mesophilic conditions in the firststage *** the second-stage chain elongation reactor,the dominating microbes were primarily from the genera Megasphaera and Caproiciproducens,shaped by varying feed and inoculum *** network analysis revealed positive correlations among species from the genera Caproiciproducens,Ruminococcus,and CAG-352,as well as Megasphaera,Bacteroides,and Solobacterium,indicating strong microbial interactions that enhance caproate *** findings suggest that producing MCCAs from expired dairy and beverage waste via lactate-mediated chain elongation is a viable method for sustainable waste management and could serve as a chemical production platform in the context of building a circular bioeconomy.

关键词： Microbial chain elongation Medium chain carboxylic acids Food waste Fermentation

Effectiveness of traditional chinese medicine nursing intervention on constipation and anxiety in chemotherapy

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Nursing Communications 2024年第10期8卷 1-6页

作者： Ming-Si Fan Hai-Lei bian Li Ni Cardiac Intensive Care Unit Shanghai East Hospital of Tongji UniversityShanghai 200120China Operating Theatre Department Shanghai East Hospital of Tongji UniversityShanghai 200120China

Background:In a study conducted from March to September 2021,124 cancer patients undergoing chemotherapy at our hospital were divided into two *** control group received routine inpatient nursing care,while the observation group received Traditional Chinese Medicine(TCM)nursing interventions in addition to routine *** analysis was conducted to compare the incidence of clinical adverse reactions,constipation scores,and changes in anxiety levels between the two *** results showed that the observation group,receiving TCM nursing interventions,had lower incidence of clinical adverse reactions and lower constipation scores compared to the control ***,anxiety levels were found to decrease significantly in the observation group *** findings suggest that incorporating TCM nursing interventions in the care of cancer patients undergoing chemotherapy may help in reducing the occurrence of adverse reactions,alleviating constipation,and managing anxiety *** research is needed to explore the full potential of integrating TCM into conventional nursing care for cancer ***:Following interventions,both groups experienced varying degrees of clinical adverse reactions,with the observation group demonstrating a significantly lower total incidence(29.03%)compared to the control *** disparity was statistically significant(P<0.05).Furthermore,improvements were observed in defecation time(0.53±0.18)points and defecation frequency(1.17±0.25)points *** findings suggest that the intervention had a positive impact on reducing adverse reactions and improving defecation ***:In a recent study,researchers found that individuals in the observation group experienced lower levels of difficulty with defecation and had a more regular defecation form compared to those in the control *** results showed a significant difference in defecation difficulty and form,with the observation g

关键词： chemotherapy cancer TCM syndrome constipation anxiety

Diagnostic Value of the Padua Score Combined with Thrombotic Biomarker Tissue Plasminogen Activator Inhibitor-1 (tPAI-1) Detection for the Risk of Deep Vein Thrombosis in Patients with Pulmonary Heart Disease

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Journal of Clinical and Nursing Research 2024年第8期8卷 137-144页

作者： Xiaoyun Zhang Xinlong Xi Wenming bian Qiang Liu Department of Cardiovascular Medicine People’s Hospital of PengzhouPengzhou 611930Sichuan ProvinceChina

This study explores the diagnostic value of combining the Padua score with the thrombotic biomarker tissue plasminogen activator inhibitor-1(tPAI-1)for assessing the risk of deep vein thrombosis(DVT)in patients with pulmonary heart *** patients often exhibit symptoms similar to venous thrombosis,such as dyspnea and bilateral lower limb swelling,complicating differential *** Padua Prediction Score assesses the risk of venous thromboembolism(VTE)in hospitalized patients,while tPAI-1,a key fibrinolytic system inhibitor,indicates a hypercoagulable *** data from hospitalized patients with cor pulmonale were retrospectively *** curves compared the diagnostic value of the Padua score,tPAI-1 levels,and their combined model for predicting DVT *** showed that tPAI-1 levels were significantly higher in DVT patients compared to non-DVT *** Padua score demonstrated a sensitivity of 82.61%and a specificity of 55.26%at a cutoff value of *** combined model had a significantly higher AUC than the Padua score alone,indicating better discriminatory ability in diagnosing DVT *** combination of the Padua score and tPAI-1 detection significantly improves the accuracy of diagnosing DVT risk in patients with pulmonary heart disease,reducing missed and incorrect *** study provides a comprehensive assessment tool for clinicians,enhancing the diagnosis and treatment of patients with cor pulmonale complicated by *** research should validate these findings in larger samples and explore additional thrombotic biomarkers to optimize the predictive model.

关键词： Padua prediction score Tissue plasminogen activator inhibitor-1(tPAI-1)detection Deep vein thrombosis(DVT) Pulmonary heart disease(cor pulmonale) Diagnostic accuracy

Prevention and Nursing of Adverse Reactions of Novel Coronavirus Inactivated Vaccine (Vero Cells)

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Journal of Clinical and Nursing Research 2024年第5期8卷 100-107页

作者： Jingyu He Muyang bian Jianan Du Liping Wang Department of Disease Control Xi’an People’s Hospital(Xi’an Fourth Hospital)Xi’an 710004China

Objective:To discuss and analyze the causes of adverse reactions caused by the inactivated novel coronavirus vaccine(Vero cells),and to propose methods of prevention and ***:A questionnaire was used to randomly select 229 adults who were vaccinated with the inactivated novel coronavirus vaccine(Vero cells)at Xi’an People’s Hospital(Xi’an Fourth Hospital).The adverse reactions were statistically ***:Among the 229 adults vaccinated with the inactivated novel coronavirus vaccine(Vero cells),30 experienced vaccination *** main reaction was local induration at the inoculation site,and dizziness was the primary systemic ***:To reduce the incidence of adverse reactions to the inactivated novel coronavirus vaccine(Vero cells),it is necessary to effectively evaluate the health status of adults before vaccination,select the correct vaccination site,and strictly implement the rules of 3-inspections,7-checks,and *** the operation process and providing thorough health education after vaccination can effectively reduce the occurrence of adverse reactions.

关键词： Novel coronavirus inactivated vaccine(Vero cells) Vaccination Adverse reactions nursing

Single-base editing in IGF2 improves meat production and intramuscular fat deposition in Liang Guang Small Spotted pigs

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Journal of Animal Science and Biotechnology 2024年第1期15卷 108-126页

作者： Tianqi Duo Xiaohong Liu Delin Mo Yu bian Shufang Cai Min Wang Ruiqiang Li Qi Zhu Xian Tong Ziyun Liang Weilun Jiang Shiyi Chen Yaosheng Chen Zuyong He State Key Laboratory of Biocontrol School of Life SciencesSun Yat-Sen UniversityGuangzhou 510275GuangdongChina Department of Pharmacology(the State‑Province Key Laboratories of Biomedicine‑Pharmaceutics of China Key Laboratory of Cardiovascular ResearchMinistry of Education)College of PharmacyHarbin Medical UniversityHarbin 150081China Hunan Provincial Key Laboratory for Genetic Improvement of Domestic Animal College of Animal Science and TechnologyHunan Agricultural UniversityChangsha 410128China

Background Chinese indigenous pigs are popular with consumers for their juiciness,flavour and meat quality,but they have lower meat ***-like growth factor 2(IGF2) is a maternally imprinted growth factor that promotes skeletal muscle growth by regulating cell proliferation and differentiation.A single nucleotide polymorphism(SNP) within intron 3 of porcine IGF2 disrupts a binding site for the repressor,zinc finger BED-type containing 6(ZBED6),leading to up-regulation of IGF2 and causing major effects on muscle growth,heart size,and backfat *** favorable mutation is common in Western commercial pig populations,but absent in most Chinese indigenous pig *** improve meat production of Chinese indigenous pigs,we used cytosine base editor 3(CBE3)to introduce IGF2 intron3-C3071T mutation into porcine embryonic fibroblasts(PEFs) isolated from a male Liang Guang Small Spotted pig(LGSS),and single-cell clones harboring the desired mutation were selected for somatic cell nuclear transfer(SCNT) to generate the founder line of IGF2^(T/T) *** We found the heterozygous progeny IGF2^(C/T) pigs exhibited enhanced expression of IGF2,increased lean meat by 18%-36%,enlarged loin muscle area by 3%-17%,improved intramuscular fat(IMF) content by 18%-39%,marbling score by 0.75-1,meat color score by 0.53-1.25,and reduced backfat thickness by 5%-16%.The enhanced accumulation of intramuscular fat in IGF2^(C/T) pigs was identified to be regulated by the PI3K-AKT/AMPK pathway,which activated SREBP1 to promote *** We demonstrated the introduction of IGF2-intron3-C3071T in Chinese LGSS can improve both meat production and quality,and first identified the regulation of IMF deposition by IGF2 through SREBP1 via the PI3KAKT/AMPK signaling *** study provides a further understanding of the biological functions of IGF2and an example for improving porcine economic traits through precise base editing.

关键词： CBE3 IGF2 Intramuscular fat Meat production PI3K-AKT/AMPK ZBED6