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知识产权视域下非法获取商业大数据的刑法规制

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河北法学 2024年第6期42卷 59-74页

作者：左坚卫彭赛嘉北京师范大学法学院北京100875

大数据具有非竞争性、财产性、非独创性以及强垄断性等特征。实践中仅以非法获取计算机信息系统数据罪规制非法获取商业大数据的行为,忽视了大数据的财产性。以侵犯商业秘密罪规制非法获取行为,则忽视了对已公开商业大数据的保护,也容... 详细信息

大数据具有非竞争性、财产性、非独创性以及强垄断性等特征。实践中仅以非法获取计算机信息系统数据罪规制非法获取商业大数据的行为,忽视了大数据的财产性。以侵犯商业秘密罪规制非法获取行为,则忽视了对已公开商业大数据的保护,也容易造成数据垄断。将商业大数据作为新型财产加以保护,则忽视了现有法律体系内可能存在的保护方案。大数据与知识产权在权利客体、权利限制以及制度目标上具有亲和性,因此可以用知识产权制度保护商业大数据。由于大数据不具有独创性,其难以成为汇编作品,但能够作为邻接权客体加以保护。因此可以在《著作权法》中规定大数据收集者的权利,并在侵犯著作权罪中增设侵犯大数据的行为类型,进而规制非法获取商业大数据的行为。

关键词：商业大数据知识产权邻接权非法获取计算机信息系统数据罪数据刑法

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人工智能在骨质疏松症诊疗中的应用进展

陕西医学杂志 2024年第3期53卷 425-427,432页

作者：彭赛卢丛兰孙中洋东部战区空军医院骨科江苏南京210002 安徽医科大学第五临床学院安徽合肥230032

骨质疏松症是一种以低骨量和骨微结构退化为特点的代谢性疾病,从而导致骨折风险增加。骨质疏松性骨折通常发生在脊椎、髋关节、前臂远端和肱骨近端,但其他部位骨骼也可受累。尽管骨质疏松症的诊断是基于双能X射线吸收仪测量的骨密度(BMD... 详细信息

骨质疏松症是一种以低骨量和骨微结构退化为特点的代谢性疾病,从而导致骨折风险增加。骨质疏松性骨折通常发生在脊椎、髋关节、前臂远端和肱骨近端,但其他部位骨骼也可受累。尽管骨质疏松症的诊断是基于双能X射线吸收仪测量的骨密度(BMD)上,但多数发生骨质疏松性骨折患者的BMD尚未达到骨质疏松症的诊断标准。不管有无发生脆性骨折,骨质疏松症的诊断率仍然很低。此外,对于骨质疏松症的治疗时机、治疗对象和药物选择等诸多方面尚无标准指南。在此背景下,人工智能(AI)研发人员根据骨质疏松症的特点开发出多种算法,有望提高该疾病的诊疗水平。现就AI在骨质疏松症诊断和治疗中的最新应用进行简要概述。

关键词：骨质疏松症骨折诊断治疗人工智能算法

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电力电网功率因数提高的意义及补偿措施

水电站机电技术 2024年第4期47卷 47-50页

作者：黄道敏张雪彭赛阳高敬祥张娜空军预警学院湖北武汉430019

电力电网中功率因数的大小对于整个电力系统的经济性和安全性都起着极其重要的作用。本文阐述了功率因数及与其相关的重要概念、物理意义,分析了影响功率因数的主要因素及功率因数过低会带来的主要问题,探讨了提高功率因数的原则、补偿... 详细信息

电力电网中功率因数的大小对于整个电力系统的经济性和安全性都起着极其重要的作用。本文阐述了功率因数及与其相关的重要概念、物理意义,分析了影响功率因数的主要因素及功率因数过低会带来的主要问题,探讨了提高功率因数的原则、补偿措施及一些容易引起困惑的问题。

关键词：功率因数电力电网补偿措施

经穴电针刺激麻醉对老年直肠癌根治术患者麻醉效果、应激反应及免疫功能的影响

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现代生物医学进展 2024年第6期24卷 1135-1139页

作者：税林辉张胜康彭赛周启周代勇徐朝军宋岚湖南中医药大学第一附属医院麻醉科湖南长沙410021 湖南中医药大学第一附属医院心胸血管外科湖南长沙410021 湖南中医药大学第一中医临床学院湖南长沙410208 湖南中医药大学医学院湖南长沙410036

目的:观察经穴电针刺激麻醉对老年直肠癌根治术患者麻醉效果、应激反应及免疫功能的影响。方法:采用随机数字表法将2022年1月~2023年5月期间在我院行直肠癌根治术的97例老年患者分为对照组(n=48,全凭静脉麻醉)和观察组(n=49,对照组的基... 详细信息

目的:观察经穴电针刺激麻醉对老年直肠癌根治术患者麻醉效果、应激反应及免疫功能的影响。方法:采用随机数字表法将2022年1月~2023年5月期间在我院行直肠癌根治术的97例老年患者分为对照组(n=48,全凭静脉麻醉)和观察组(n=49,对照组的基础上接受经穴电针刺激麻醉)。对比两组麻醉药物追加量、血流动力学、疼痛评分、免疫功能指标、应激反应指标和不良反应情况。结果:与对照组相比,观察组的罗库溴铵用量、丙泊酚用量、瑞芬太尼用量更少(P0.05)。结论:经穴电针刺激麻醉用于老年直肠癌根治术患者,可减少其他麻醉药物的用药量,减轻疼痛,维持血流动力学稳定,减轻应激反应,改善免疫抑制,具有良好的麻醉效果。

关键词：经穴电针刺激麻醉老年直肠癌根治术麻醉效果应激反应免疫功能

The evolution and functional divergence of 10 Apolipoprotein D-like genes in Nilaparvata lugens

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Insect Science 2024年第1期31卷 91-105页

作者： Jia-Bao Lu peng-peng Ren Qiao Li Fang He Zhong-Tian Xu sai-Nan Wang Jian-Ping Chen Jun-Min Li Chuan-Xi Zhang Citrus Research Institute Southwest University/Chinese Academy of Agricultural SciencesNational Engineering Research Center for CitrusChongqingChina Technology Center of Wuhan Customs District HubeiChina Institute of Insect Science Zhejiang UniversityHangzhouChina

Apolipoprotein D(ApoD),a member of the lipocalin superfamily of proteins,is involved in lipid transport and stress *** only a single copy of the ApoD gene is found in humans and some other vertebrates,there are typically several ApoD-like genes in *** date,there have been relatively few studies that have examined the evolution and functional differentiation of ApoD-like genes in insects,particularly hemi-metabolous *** this study,we identified 10 ApoD-like genes(NlApoD1−10)with distinct spatiotemporal expression patterns in Nilaparvata lugens(BPH),which is an important pest of ***1−10 were found to be distributed on 3 chromosomes in a tandem array of NlApoD1/2,NlApoD3−5,and NlApoD7/8,and show sequence and gene structural divergence in the coding regions,indicating that multiple gene duplication events occurred during *** analysis revealed that NlApoD1−10 can be clustered into 5 clades,with NlApoD3−5 and NlApoD7/8 potentially evolving exclusively in the Delphacidae *** screening using an RNA interference approach revealed that only NlApoD2 was essential for BPH development and survival,whereas NlApoD4/5 are highly expressed in testes,and might play roles in ***,stress response analysis revealed that NlApoD3−5/9,NlApoD3−5,and NlApoD9 were up-regulated after treatment with lipopolysaccharide,H2O2,and ultraviolet-C,respectively,indicating their potential roles in stress resistance.

关键词： Apolipoprotein D BPH evolution functional divergence gene duplication NIApoD

Evolution and function of residual solvent in polymer-Li2B12H12 composite solid electrolyte

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Rare Metals 2024年第08期43卷 3748-3757页

作者： Xiang-Yang Ye Ke-Pan Bao sai-Nan Luo Xin Li Tai-Qiang Chen Shui-Xin Xia Tao Yuan Yue-peng Pang Shi-You Zheng School of Materials and Chemistry University of Shanghai for Science and Technology Department of Materials Science and Engineering National University of Singapore

Composite solid electrolytes（CSEs） containing polymer matrices and inorganic fillers hold promise for the next generation of solid-state ***,the role of residual solvents in CSEs remains *** study investigated the evolution and function of the residual solvent in a polymer-Li2B12H12CSE.A partial reaction occurred between Li2B12H12and solvent N,N-dimethylformamide（DMF）,which produced dimethylaminomethanol（DMAM） in the *** functional theory calculations have revealed that DMA M forms stronger hydrogen bonds with polyvinylidene fluoride chains than DMF,which can have a plasticizing effect on the polymer matrix,leading to lower crystallinity and quicker segment ***,this CSE exhibited improved Li-ion conducting properties,enabling the stable cycling of Li‖LiFePO4solid-state *** study provided insights into the role of residual solvents in CSEs.

关键词： Composite solid electrolyte Residual solvent Lithium borohydride Plasticizing effect

湘南烟稻轮作区植烟土壤养分时空演变特征及肥力评价

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中国农学通报 2024年第20期40卷 54-64页

作者：郝汉驰李耀肖子曼陈莎莎彭赛林小若苏梦洁肖艳松李小慧刘勇军侯红波龙坚彭佩钦中南林业科技大学环境科学与工程学院长沙410004 湖南省烟草公司郴州市公司湖南郴州423015 湖南省烟草公司永州市公司湖南永州425000 湖南省烟草科学研究所长沙410004

为了解湘南烟稻轮作区植烟土壤肥力变化特征及当前土壤肥力水平,更好地管理植烟土壤资源及培肥改良土壤提供依据。以郴州市和永州市下辖10个地区为研究区域,通过对2010、2015、2022年土壤pH、有机质及其关键元素进行综合分析,系统评价... 详细信息

为了解湘南烟稻轮作区植烟土壤肥力变化特征及当前土壤肥力水平,更好地管理植烟土壤资源及培肥改良土壤提供依据。以郴州市和永州市下辖10个地区为研究区域,通过对2010、2015、2022年土壤pH、有机质及其关键元素进行综合分析,系统评价了土壤肥力的变化情况。结果表明:相比2010年,2022年湘南烟稻轮作区植烟土壤pH和有效锰相对稳定,土壤有机质、碱解氮、全钾和有效钼分别下降了9.78%、19.71%、32.37%和66.67%,而全磷、有效磷和速效钾却分别显著上升了26.37%、76.78%和122.53%,土壤中微量元素(水溶性氯、有效铁、有效铜、有效硼和交换性镁)也出现显著增加。经过12年的生产利用,湘南各地区土壤综合肥力值均有提升,稻作烟区综合肥力指数整体提高了0.190个单位,肥力等级由中等提升至较高等级,肥力显著提高。烟草施肥应稳pH控氮、磷增钾,增施钼元素肥料,保持锰元素施肥水平,减少氯和锌等中微量元素肥料的用量。

关键词：植烟土壤烟稻轮作肥力评价肥力变化

Next-generation sequencing reveals relapse and leukemia-free survival risks in newly diagnosed acute myeloid leukemia treated with CAG regimen combined with decitabine

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Cancer Pathogenesis and Therapy 2024年第2期2卷 112-120页

作者： sai Huang peng Chen Lu Wang Lingmin Xu Nan Wang Fei Li Liping Dou Daihong Liu Department of Hematology Senior Department of HematologyThe Fifth Medical Center of PLA General HospitalBejing 100039China National Clinical Research Center of Geriatric Diseases Chinese PLA General HospitalBejing 100853China Chinese PLA Medical School Beijing 100853China Department of Hematology The First Medical Center of PLA General HospitalBejing 100853China

Background:Acute myeloid leukemia(AML)is a heterogeneous hematopoietic malignancy whose prognosis is associated with several ***,a deoxyribonucleic acid(DNA)methyltransferase(DNMT)in-hibitor,combined with cytarabine,aclarubicin hydrochloride,and granulocyte colony-stimulating factor(DCAG),has been used in patients newly diagnosed with *** regimen has been especially used in older and fragile patients who are immunocompromised or have co-morbidities,as well as those with specific gene ***,the integration of molecular risk stratification and treatment guidance for the DCAG regimen has not been well ***,this study aimed to investigate the genetic mutations associated with AML and establish appropriate treatment strategies for patients newly diagnosed with ***:This study analyzed the clinical data and genetic mutations based on next-generation sequencing(NGS)in 124 newly diagnosed patients with AML who received the DCAG regimen at the People's Liberation Army(PLA)General Hospital from January 2008 to August *** associated with the cumulative incidence of relapse(CIR)and leukemia-free survival(LFS)in patients newly diagnosed with AML were ***:The most adverse prognosis of DCAG-treated patients was observed in those with FLT3-ITD,KIT,PTPN11,GATA2,or IDH1 mutations during univariable analysis,whereas PTPN11 mutation was solely significant in multivariable analysis,with an increased likelihood of CIR(P=0.001)and reduced LFS duration(P=0.077).Hyperleukocytosis was maintained as an independent risk factor for increased CIR risk(P=0.044)and decreased LFS duration(P=0.042)in multivariable *** this study,we validated the risk classification of patients with AML receiving an epigenetic modifier-based induction regimen across a broad age ***:NGS demonstrated a dismal overall outcome in patients with the rare PTPN11 mutations,indicating the need for new therapies that target this h

关键词： Acute myeloid leukemia Next-generation sequencing Prognosis DNA methyltransferase Chemotherapy

Hi-Tag:a simple and efficient method for identifying protein-mediated long-range chromatin interactions with low cell numbers

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Science China(Life Sciences) 2024年第5期67卷 1027-1034页

作者： Xiaolong Qi Lu Zhang Qiulin Zhao peng Zhou sai Xian Zhang Jingjin Li Zhuqing Zheng Yue Xiang Xueting Dai Zhe Jin Yaobang Jian Xinyun Li Liangliang Fu Shuhong Zhao Key Lab of Agricultural Animal Genetics Breeding and Reproduction of Ministry of Education and Key Laboratory of Swine Genetics and Breeding of Ministry of AgricultureCollege of Animal Science and TechnologyHuazhong Agricultural UniversityWuhan 430070China The Cooperative Innovation Center for Sustainable Pig Production Wuhan 430070China Hubei Hongshan Laboratory Frontiers Science Center for Animal Breeding and Sustainable ProductionWuhan 430070China

Protein-mediated chromatin interactions can be revealed by coupling proximity-based ligation with chromatin ***,these techniques require complex experimental procedures and millions of cells per experiment,which limits their widespread application in life science ***,we develop a novel method,Hi-Tag,that identifies high-resolution,long-range chromatin interactions through transposase tagmentation and chromatin proximity ligation(with a phosphorothioate-modified linker).Hi-Tag can be implemented using as few as 100,000 cells,involving simple experimental procedures that can be completed within 1.5 ***,Hi-Tag is capable of using its own data to identify the binding sites of specific proteins,based on which,it can acquire accurate interaction *** results suggest that Hi-Tag has great potential for advancing chromatin interaction studies,particularly in the context of limited cell availability.

关键词： Hi-Tag chromatin interactions transposase tagmentation chromatin proximity ligation low cell numbers

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