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Capillary leak syndrome:A rare cause of acute respiratory distress syndrome

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World Journal of Clinical Cases 2022年第13期10卷 4324-4326页

作者： Deven Juneja sahil Kataria Department ofCritical Care Medicine Max Super Speciality HospitalDelhi 110017India

Capillary leak syndrome(CLS)is a rare clinical syndrome associated with significant morbidity and *** care and supportive therapy constitute the mainstay of the treatment,along with judicious use of crystalloids and colloids such as dextran and starch during the leak *** advantages of proning,steroids,and intravenous immunoglobins are worth contemplating in patients with such a *** membrane oxygenation appears to be an excellent strategy to surmount the impediments of the leak and post leak phase of CLS,especially in patients with severe or refractory hypoxemia.

关键词： Extracorporeal membrane oxygenation Capillary leak syndrome Organophosphorus poisoning Hemodynamics

Ethics Aware Object Oriented Smart City Architecture

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China Communications 2017年第5期14卷 160-173页

作者： sahil Sholla Roohie Naaz Mohammad Ahsan Chishti Computer Science and Engineering Department National Institute of Technology SrinagarHazratbal 190006India

A novel initiative in providing advanced civic amenities is the idea of smart city driven by the lnternet of Things. Owing to a lack of consensus regarding what constitutes a smart city, diverse smart city architectures have been proposed. However, it is observed that adequate consideration is not given to the most important element of a smart city i.e. its people. In our opinion, energy efficient technologically driven city does not necessarily lead to a smart city. Ethics, tradition and law form essential ingredients of complex social palette that cannot be ignored. In this work we propose Ethics-Aware Object-Oriented Smart City Architecture （EOSCA） that has two distinguishing features. Firstly, we propose an object oriented layered architecture where an object represents an abstraction of a real world thing along with requisite security and ethics parameters. Secondly, we propose to integrate socio-cultural and ethical aspects within the smart city architecture by dedicating a separate ethics layer. Such enhancement not only addresses the challenge of privacy and security of a smart city, but also makes it people friendly by incorporating ethics. Such measures would facilitate social acceptance of smart city paradigm and augment its economic value.

关键词： internet of things smart city architecture ethics law society

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Approach to thromboelastography-based transfusion in cirrhosis:An alternative perspective on coagulation disorders

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World Journal of Gastroenterology 2023年第9期29卷 1460-1474页

作者： sahil Kataria Deven Juneja Omender Singh Institute of Critical Care Medicine Max Super Speciality HospitalNew Delhi 110017India

Viscoelastic tests,specifically thromboelastography and rotational thromboelastometry,are increasingly being used in the management of postoperative bleeding in surgical intensive care units(ICUs).However,life-threatening bleeds may complicate the clinical course of many patients admitted to medical ICUs,especially those with underlying liver *** with cirrhosis have multiple coagulation abnormalities that can lead to bleeding or thrombotic *** to conventional coagulation tests,a comprehensive depiction of the coagulation process and point-of-care availability are advantages favoring these devices,which may aid physicians in making a rapid diagnosis and instituting early *** tests may help predict bleeding and rationalize the use of blood products in these patients.

关键词： Bleeding Chronic liver disease Cirrhosis Thromboelastography Viscoelastic tests

Towards the Design of Ethics Aware Systems for the Internet of Things

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China Communications 2020年第2期17卷 239-252页

作者： sahil Sholla Roohie Naaz Mir Mohammad Ahsan Chishti Computer Science and Engineering Department National Institute of Technology Srinagar

The Internet of Things promises to offer numerous societal benefits by providing a spectrum of user applications. However, ethical ramifications of adopting such pervasive technology on a society-wide scale have not been adequately considered. Smart things endowed with artificial intelligence may carry out decisions that entail ethical consequences. It is assumed that the functioning of a smart device does not involve any ethical responsibility vis-a-vis its application context. Such a perspective may precipitate situations that endanger essential human values or cause physical or emotional harm. Therefore, it is necessary to consider the design of ethics within intelligent systems to safeguard human interests. In order to address these concerns, we propose a novel method based on Boolean algebra that enables a machine to exhibit varying ethical behaviour by employing the concept of ethics categories and ethics modes. Such enhancement of smart things offers a way to design ethically compliant smart devices and paves way for human friendly technology ecosystems.

关键词： Boolean ethics aware ethical design Internet of Things

Therapies to modulate gut microbiota:Past,present and future

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World Journal of Gastroenterology 2020年第8期26卷 777-788页

作者： Akshita Gupta Srishti Saha sahil Khanna Department of Medicine All India Institute of Medical SciencesNew Delhi 110029India Division of Gastroenterology and Hepatology Mayo ClinicRochesterMN 55905United States

The human gut microbiota comprises of a complex and diverse array of microorganisms,and over the years the interaction between human diseases and the gut microbiota has become a subject of growing *** microbial milieu in the gastrointestinal tract is central to the pathogenesis of several diseases including antibiotic-associated diarrhea and Clostridioides difficile infection(CDI).Manipulation of this microbial milieu to restore balance by microbial replacement therapies has proven to be a safe and effective treatment for recurrent *** is considerable heterogeneity in various aspects of stool processing and administration for fecal microbiota transplantation(FMT)across different centers globally,and standardized microbioal replacement therapies offer an attractive *** adverse effects associated with FMT are usually ***,there is paucity of data on long term safety of FMT and there is a need for further studies in this *** our increasing understanding of the host-microbiome interaction,there is immense potential for microbial replacement therapies to emerge as a treatment option for several *** role of microbioal replacement therapies in diseases other than CDI is being extensively studied in ongoing clinical trials and it may be a potential treatment option for inflammatory bowel disease,irritable bowel syndrome,obesity,multidrug resistant infections,and neuropsychiatric *** microbiota transplantation for non-CDI disease states should currently be limited only to research settings.

关键词： Fecal microbiota transplantation Microbial replacement therapies Clostridioides difficile infection Microbiome Microbiota Inflammatory bowel disease

Towards the Design of Ethics Aware Systems for the Internet of Things

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China Communications 2019年第9期16卷 209-221页

作者： sahil Sholla Roohie Naaz Mir Mohammad Ahsan Chishti Computer Science and Engineering Department National Institute of Technology Srinagar

The Internet of Things promises to offer numerous societal benefits by providing a spectrum of user ***,ethical ramifications of adopting such pervasive technology on a society-wide scale have not been adequately *** things endowed with artificial intelligence may carry out decisions that entail ethical *** is assumed that the functioning of a smart device does not involve any ethical responsibility vis-a-vis its application *** a perspective may precipitate situations that endanger essential human values or cause physical or emotional ***,it is necessary to consider the design of ethics within intelligent systems to safeguard human *** order to address these concerns,we propose a novel method based on Boolean algebra that enables a machine to exhibit varying ethical behaviour by employing the concept of ethics categories and ethics *** enhancement of smart things offers a way to design ethically compliant smart devices and paves way for human friendly technology ecosystems.

关键词： Boolean ethics aware ethical design Internet of Things

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Biochar-mediated removal of pharmaceutical compounds from aqueous matrices via adsorption

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Waste Disposal and Sustainable Energy 2023年第1期5卷 37-62页

作者： sahil Chauhan Tajamul Shafi Brajesh Kumar Dubey Shamik Chowdhury School of Environmental Science and Engineering Indian Institute of Technology KharagpurKharagpurWest Bengal721302India Department of Civil Engineering Indian Institute of Technology KharagpurKharagpurWest Bengal721302India

Pharmaceutical is one of the noteworthy classes of emerging contaminants. These biologically active compounds pose a range of deleterious impacts on human health and the environment. This is attributed to their refractory behavior, poor biodegradability, and pseudopersistent nature. Their large-scale production by pharmaceutical industries and subsequent widespread utilization in hospitals, community health centers, and veterinary facilities, among others, have significantly increased the occurrence of pharmaceutical residues in various environmental compartments. Several technologies are currently being evaluated to eliminate pharmaceutical compounds (PCs) from aqueous environments. Among them, adsorption appears as the most viable treatment option because of its operational simplicity and low cost. Intensive research and development efforts are, therefore, currently underway to develop inexpensive adsorbents for the effective abatement of PCs. Although numerous adsorbents have been investigated for the removal of PCs in recent years, biochar-based adsorbents have garnered tremendous scientific attention to eliminate PCs from aqueous matrices because of their decent specific surface area, tunable surface chemistry, scalable production, and environmentally benign nature. This review, therefore, attempts to provide an overview of the latest progress in the application of biochar for the removal of PCs from wastewater. Additionally, the fundamental knowledge gaps in the domain knowledge are identified and novel strategic research guidelines are laid out to make further advances in this promising approach towards sustainable development.

关键词： Pharmaceuticals Adsorption Adsorbents Biochar Wastewater treatment

Exploring Personalized Internet of Things(PIoT),social connectivity,and Artificial Social Intelligence(ASI):A survey

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High-Confidence Computing 2024年第3期4卷 136-162页

作者： Bisma Gulzar Shabir Ahmad Sofi sahil Sholla Department of Information Technology National Institute of TechnologySrinagar 190001India Department of Computer Science and Engineering Islamic University of Science and TechnologyGazipur 1700India

Pervasive Computing has become more personal with the widespread adoption of the Internet of Things(IoT)in our day-to-day *** emerging domain that encompasses devices,sensors,storage,and computing of personal use and surroundings leads to Personal IoT(PIoT).PIoT offers users high levels of personalization,automation,and *** proliferation of PIoT technology has extended into society,social engagement,and the interconnectivity of PIoT objects,resulting in the emergence of the Social Internet of Things(SIoT).The combination of PIoT and SIoT has spurred the need for autonomous learning,comprehension,and understanding of both the physical and social *** research on PIoT is dedicated to enabling seamless communication among devices,striking a balance between observation,sensing,and perceiving the extended physical and social environment,and facilitating information ***,the virtualization of independent learning from the social environment has given rise to Artificial Social Intelligence(ASI)in PIoT ***,autonomous data communication between different nodes within a social setup presents various resource management challenges that require careful *** paper provides a comprehensive review of the evolving domains of PIoT,SIoT,and ***,the paper offers insightful modeling and a case study exploring the role of PIoT in post-COVID *** study contributes to a deeper understanding of the intricacies of PIoT and its various dimensions,paving the way for further advancements in this transformative field.

关键词： Personal Internet of Things(PIoT) Artificial Social Intelligence(ASI) Hyperpersonalization

Stool banking for fecal microbiota transplantation:ready for prime time?

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Hepatobiliary Surgery and Nutrition 2021年第1期10卷 110-112页

作者： Srishti Saha sahil Khanna Division of Gastroenterology and Hepatology Mayo ClinicRochesterMNUSA

Fecal microbiota transplantation(FMT)has emerged as an effective treatment for recurrent Clostridioides difficile infection(CDI)and is recommended as a standard of care(1).Since the first randomized clinical trial published in 2013,there has been an exponential rise in the number of FMTs being performed(2).However,access to FMT varies according to location and type of healthcare establishment and is complicated by the regulatory issues surrounding its use(3,4).Storing and banking stool may be an accessible and economical option for patients requiring FMT,considering the costs associated with donor screening,stool processing and storage by individual providers(5).

关键词： clinical donor exponential