检索结果-南通市图书馆

放电等离子烧结法制备原位TiB增强Ti-6Al-4V复合材料的显微组织特征（英文）

Transactions of Nonferrous Metals Society of China 2015年第5期25卷 1460-1467页

作者： saeid ghesmati tabrizi Abolfazl BABAKHANI Seyed Abdolkarim SAJJADI 吕维洁 Department of Materials Science and Engineering Engineering Faculty Ferdowsi University of Mashhad 上海交通大学材料科学与工程学院金属基复合材料国家重点实验室上海200240

钛基复合材料在运输和航空工业领域具有广泛的应用。以Ti-6Al-4V和B4C为原料分别采用冷压-真空烧结和放电等离子烧结两种方法制备Ti B晶须增强钛基复合材料。考察不同复合材料Ti B晶须的分布、大小以及长径比,研究放电等离子烧结温度对T... 详细信息

钛基复合材料在运输和航空工业领域具有广泛的应用。以Ti-6Al-4V和B4C为原料分别采用冷压-真空烧结和放电等离子烧结两种方法制备Ti B晶须增强钛基复合材料。考察不同复合材料Ti B晶须的分布、大小以及长径比,研究放电等离子烧结温度对Ti B晶须增强钛基复合材料的影响。光学显微镜(OM),扫描电镜(SEM)以及EDS分析结果表明:将放电等离子烧结温度从900°C升高到1100°C可以使Ti B晶须原位自生反应完全,同时减少材料的孔隙含量。

关键词： Ti-6Al-V金属基复合材料 TiB晶须原位反应放电等离子烧结法

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Increased levels of miR-124 in human dental pulp stem cells alter the expression of neural markers

引用

Journal of Otology 2019年第4期14卷 121-127页

作者： Ameneh Mehri-Ghahfarrokhi Zahra Pourteymourfard-tabrizi Effat Farrokhi Morteza Hashemzadeh Chaleshtori Mohammad-saeid Jami Department of Molecular Medicine School of Advanced TechnologiesShahrekord University of Medical SciencesShahrekordIran Cellular and Molecular Research Center Basic Health Sciences InstituteShahrekord University of Medical SciencesShahrekordIran Department of Neurology David Geffen School of MedicineUniversity of California Los Angeles(UCLA)Los AngelesCAUSA

Auditory neuropathy is the particular form of deafness in humans which cannot be treated by replacement *** dental pulp stem cells(hDPSCs)are derived from an ectomesenchymal neural crest cell ***,they possess a promising capacity for neuronal differentiation and ***-124,a key regulator of neuronal development in the inner ear,is expressed at high levels in auditory and vestibular ***,we evaluated the possible effect of miR-124 in alteration of neural protein markers *** quantitative reverse transcription-PCR(qRT-PCR)analyses and immunofluorescence staining,we studied the expression patterns of neural progenitor markers(Nestin,NOTCH1,and SOX2)and neural markers(b-tubulin Ⅲ,GATA-3,and peripherin)upon transfection of hDPSCs with *** qRT-PCR results showed that Nestin was upregulated 6 h *** contrast,Nestin expression exhibited a decreasing trend 24 h and 48 h *** levels of b-tubulin Ⅲ,6 h and 16 h post transfection in RNA level as compared with control cells,were determined in transfected ***,b-tubulin-Ⅲ expression decreased 48 h *** immunoflourescence results indicated that transfection of hDPSCs with miR-124,only affected Nestin among the studied neural progenitor and neural marker expression in protein level.

关键词： Sensorineural hearing loss miR-124 Spiral ganglion neurons Nestin DPSCs

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Protein biomarkers of neural system

引用

Journal of Otology 2019年第3期14卷 77-88页

作者： Fatemeh Ghanavatinejad Zahra Pourteymour Fard tabrizi Shadi Omidghaemi Esmaeel Sharifi Simon Geir Moller Mohammad-saeid Jami Cellular and Molecular Research Center Basic Health Sciences Institute Shahrekord University of Medical Science Shahrekord Iran Department of Tissue Engineering and Biomaterials School of Advanced Medical Sciences and Technologies Hamadan University of Medical Sciences Hamadan Iran Department of Biological Sciences St John's University New York NY USA The Norwegian Centre for Movement Disorders Stavanger University Hospital Norway Department of Neurology David Geffen School of Medicine University of California Los Angeles CA 90095 USA

The utilization of biomarkers for in vivo and in vitro research is growing rapidly. This is mainly due to the enormous potential of biomarkers in evaluating molecular and cellular abnormalities in cell models and in tissue, and evaluating drug responses and the effectiveness of therapeutic intervention strategies. An important way to analyze the development of the human body is to assess molecular markers in embryonic specialized cells, which include the ectoderm, mesoderm, and endoderm. Neuronal development is controlled through the gene networks in the neural crest and neural tube, both components of the ectoderm. The neural crest differentiates into several different tissues including, but not limited to, the peripheral nervous system, enteric nervous system, melanocyte, and the dental pulp. The neural tube eventually converts to the central nervous system. This review provides an overview of the differentiation of the ectoderm to a fully functioning nervous system, focusing on molecular biomarkers that emerge at each stage of the cellular specialization from multipotent stem cells to completely differentiated cells. Particularly, the otic placode is the origin of most of the inner ear cell types such as neurons, sensory hair cells, and supporting cells. During the development, different auditory cell types can be distinguished by the expression of the neurogenin differentiation factor1 (Neuro D1), Brn3a, and transcription factor GATA3. However, the mature auditory neurons express other markers including bIII tubulin, the vesicular glutamate transporter (VGLUT1), the tyrosine receptor kinase B and C (Trk B, C), BDNF, neurotrophin 3 (NT3), Calretinin, etc.

关键词： Neural system Biomarker Differentiation Stem cell Nervous system Otic placode

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：