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Double guidewire technique vs transpancreatic precut sphincterotomy in difficult biliary cannulation

World Journal of Gastroenterology 2013年第1期19卷 108-114页

作者： Young Wook Yoo Sang-Woo Cha Woong Cheul Lee sae hee kim Anna kim Young Deok Cho Department of Internal Medicine Gastroenterology and Hepatobiliary CenterCheongju St.Mary's HospitalCheongju 360-568South Korea Department of Internal Medicine Soonchunhyang University College of MedicineInstitute for Digestive ResearchDigestive Disease CenterSoonchunhyang University HospitalSeoul 140-743South Korea Division of Gastroenterology Department of Internal MedicineEulji University College of MedicineEulji University HospitalDaejeon 302-799South Korea

AIM:To compare the outcomes between doubleguidewire technique(DGT) and transpancreatic precut sphincterotomy(TPS) in patients with difficult biliary ***:This was a prospective,randomized study conducted in single tertiary referral hospital in *** January 2005 and September 2010.A total of 71 patients,who bile duct cannulation was not possible and selective pancreatic duct cannulation was achieved,were randomized into DGT(n = 34) and TPS(n = 37) *** or TPS was done for selective biliary *** measured the technical success rates of biliary cannulation,median cannulation time,and procedure related ***:The distribution of patients after randomization was balanced,and both groups were comparable in baseline characteristics,except the higher percentage of endoscopic nasobiliary drainage in the DGT group(55.9% vs 13.5%,P < 0.001).Successful cannulation rate and mean cannulation times in DGT and TPS groups were 91.2% vs 91.9% and 14.1 ± 13.2 min vs 15.4 ± 17.9 min,P = 0.732,*** was no significant difference between the two *** overall incidence of post-endoscopic retrograde cholangiopancreatography(ERCP) pancreatitis was 38.2% vs 10.8%,P < 0.011 in the DGT group and the TPS group;post-procedure pancreatitis was significantly higher in the DGT *** the overall incidence of post-ERCP hyperamylasemia was no significant difference between the two groups;DGT group vs TPS group:14.7% vs 16.2%,P < ***:When free bile duct cannulation was difficult and selective pancreatic duct cannulation was achieved,DGT and TPS facilitated biliary cannulation and showed similar success ***,post-procedure pancreatitis was significantly higher in the DGT group.

关键词： Endoscopic retrograde cholangiopancreatography Post-endoscopic retrograde cholangiopancreatography pancreatitis Duoble guidewire technique Transpancrestic precut sphincterotomy

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Colonoscopy-induced ischemic colitis in patients without risk factors

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World Journal of Gastroenterology 2014年第13期20卷 3698-3702页

作者： Sang Ok Lee sae hee kim Sung hee Jung Chan Woong Park Min Ji Lee Jin A Lee Hyun Cheol Koo Anna kim Hyun-Young Han Dong-Wook Kang Division of Gastroenterology Department of Internal MedicineEulji University College of MedicineEulji University HospitalDaejeon 302-779South Korea Department of radiology Eulji University College of MedicineEulji University HospitalDaejeon 302-779South Korea Department of pathology Eulji University College of MedicineEulji University HospitalDaejeon 302-779South Korea

Ischemic colitis is the most common form of intestinal *** is a condition that is commonly seen in the elderly and among individuals with risk factors for *** predisposing conditions for ischemic colitis are major vascular occlusion,small vessel disorder,shock,some medications,colonic obstructions and hematologic *** colitis following colonoscopy is ***,we report two cases of ischemic colitis after a routine screening colonoscopy in patients without risk factors for ischemia.

关键词： Ischemic colitis Colonoscopy Hematochezia

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Pancreatic pseudocyst filled with semisolid lipids mimicking solid mass on endoscopic ultrasound

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World Journal of Gastroenterology 2010年第8期16卷 1034-1038页

作者： Sang-Woo Cha sae hee kim Hyang Ie Lee Yun Jung Lee Hyeon Woong Yang Sung hee Jung Anna kim Min Koo Lee Hyun Young Han Dong Wook Kang Division of Gastroenterology Department of Internal Medicine Eulji University College of Medicine Eulji University Hospital Division of Gastroenterology Department of Surgery Eulji University College of Medicine Eulji University Hospital Division of Gastroenterology Department of Radiology Eulji University College of Medicine Eulji University Hospital Division of Gastroenterology Department of Pathology Eulji University College of Medicine Eulji University Hospital

Pancreatic pseudocysts,which account for 70%-90% of pancreatic cystic lesions,characteristically are non-epithelially lined cystic cavities that are contiguous with the pancreas. Pancreatic pseudocysts can be caused by acute,chronic or traumatic pancreatitis and should be differentiated from other pancreatic diseases with cystic appearances,especially cystic neoplasms. We report a unique case of a pancreatic pseudocyst filled with semisolid lipids,which appeared by endoscopic ultrasound as a solid mass,and was therefore resected.

关键词： Pancreatic pseudocyst Lipids Endosonog-raphy

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Aligned Ion Conduction Pathway of Polyrotaxane‑Based Electrolyte with Dispersed Hydrophobic Chains for Solid‑State Lithium–Oxygen Batteries

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Nano-Micro Letters 2025年第2期17卷 169-186页

作者： Bitgaram kim Myeong‑Chang Sung Gwang‑hee Lee Byoungjoon Hwang Sojung Seo Ji‑Hun Seo Dong‑Wan kim Department of Materials Science and Engineering Korea University145 Anam‑RoSeongbuk‑GuSeoul 02841Republic of Korea School of Civil Environmental and Architectural EngineeringKorea University145 Anam‑RoSeongbuk‑GuSeoul 02841Republic of Korea Materials Science and Chemical Engineering Center Institute for Advanced Engineering(IAE)Yongin 17180Republic of Korea

A critical challenge hindering the practical application of lithium–oxygen batteries(LOBs)is the inevitable problems associated with liquid electrolytes,such as evaporation and safety *** study addresses these problems by proposing a modified polyrotaxane(mPR)-based solid polymer electrolyte(SPE)design that simultaneously mitigates solvent-related problems and improves ***-SPE exhibits high ion conductivity(2.8×10^(−3)S cm^(−1)at 25℃)through aligned ion conduction pathways and provides electrode protection ability through hydrophobic chain *** this mPR-SPE into solid-state LOBs resulted in stable potentials over 300 *** situ Raman spectroscopy reveals the presence of an LiO_(2)intermediate alongside Li_(2)O_(2)during oxygen *** situ X-ray diffraction confirm the ability of the SPE to hinder the permeation of oxygen and moisture,as demonstrated by the air permeability *** present study suggests that maintaining a low residual solvent while achieving high ionic conductivity is crucial for restricting the sub-reactions of solid-state LOBs.

关键词： Solid polymer electrolyte Lithium-oxygen batteries Polyrotaxane ion conductivity Hydrophobic chain

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Hyperlipidemia and erectile dysfunction

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Asian Journal of Andrology 2000年第3期2卷 161-166页

作者： sae-Chul kim Department of Urology College of Medicine Chung-Ang University Seoul Korea

We have done consecutive studies to investigate the effects of impaired lipid metabolism on the contractile and re-laxation response of cavernous smooth muscles and to elucidate its pathogenesis: 1) incidence of hyperlipidemia in im-potent patients; 2) erection response to intracavemous injection of papaverine in impotent patients with hyperlipidemia;3) relaxation responses of isolated cavemosal smooth muscles to endothelium-independent and endothelium-dependentvasodilators in impotent patients with hypercholesterolemia or hypertriglyceridemia; 4) involvement of superoxide radi-cal in the impaired endothelium-dependent relaxation of cavemous smooth muscle in hypercholesterolemic rabbits; S)effects of isolated lipoproteins and triglyceride, combined oxidized LDL plus triglyceride, and combined oxidized LDLplus HDL on contractile and relaxation response of rabbit cavemous smooth muscles; 6) involvement of e-NOS in theimpaired endothelium-dependent relaxation of cavemous smooth muscle in hypercholesterolemic rabbit. Hypercholes-terolemia may cause impairment of endothelium-dependent relaxation. Oxidized LDL is the major causative cholesterolof the impaired relaxation response. A chain reaction, the production of superoxide radicals and functional impairmentof eNOS may be a major cause of the functional impairment in the early stages of hypercholesterolemia.

关键词： hypercholesterolemia hypertriglyceridemia LDL lipoproteins HDL lipoproteins superoxide radicals NO synthase cavemous smooth muscle erectile dysfunction

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Recent advancement in diagnosis of vasculogenic impotence

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Asian Journal of Andrology 1999年第1期1卷 37-43页

作者： sae Chul kim Department of Urology College of Medicine Chung-Ang University Seoul Korea

Several dynamic tests with vasoactive drags are available for evaluating penile vascular inflows and outflows,ranging from simple pharmacologic test to more invasive radiologic sets. However, there is still no perfect single testto reflect the penile vascular flow. All possible efforts should be exerted to get the greatest erectile effect to avoid anunderestimation of blood flow to the corpora due to incomplete relaxation of the trabecular smooth *** of the type and frequency of anatomical variations and potential collateral routes is important in interpretingpenile arterograms and in evaluating the hemodynamic significance of suspected arterial disease. Choice of the vasculartests should always depend on the purpose of testing.

关键词： vasculogenic impotence diagnosis cavernosography cavernosometry penile erection blood flow velocity hemodynamics angiography

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Factors affecting length of stay according to bronchopulmonary dysplasia severity:a nationwide cohort study in Korea

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World Journal of Pediatrics 2024年第5期20卷 470-480页

作者： Hye Mi Lee Jeongmin Shin sae Yun kim So Young kim Department of Pediatrics College of MedicineThe Catholic University of KoreaSeoulRepublic of Korea Department of Pediatrics Yeouido St.Mary’s HospitalCollege of MedicineThe Catholic University of Korea1063-roYeongdeungpo-guSeoul07345Republic of Korea

Background Longer hospitalizations for preterm infants with bronchopulmonary dysplasia(BPD)delay developmental outcomes,increase the risk for hospital-acquired complications,and exert a substantial socioeconomic *** study aimed to identify factors associated with an extended length of stay(LOS)at different levels of severity of *** A cohort study was conducted using the Korean Neonatal Network registry of very low birth weight infants with BPD between 2013 and 2017 through retrospective *** A total of 4263 infants were diagnosed with *** mild BPD,infants requiring surgical treatment for patent ductus arteriosus needed a longer LOS[eadjustedβcoefficients(adjβ)1.041;95%confidence interval(CI):0.01–0.08]and hydrocephalus(eadjβ1.094;95%CI 0.01–0.17).In moderate BPD,infants administered steroids or with intraventricular hemorrhage required a longer LOS(eadjβ1.041;95%CI 0.00–0.07 and eadjβ1.271;95%CI 0.11–0.38,respectively).In severe BPD,infants with comorbidities required a longer LOS:pulmonary hypertension(eadjβ1.174;95%CI 0.09–0.23),administrated steroid for BPD(eadjβ1.116;95%CI 0.07–0.14),sepsis(eadjβ1.062;95%CI 0.01–0.11),patent ductus arteriosus requiring surgical ligation(eadjβ1.041;95%CI 0.00–0.08),and intraventricular hemorrhage(eadjβ1.016;95%CI 0.05–0.26).Additionally,the higher the clinical risk index score,the longer the LOS needed for infants in all *** The factors affecting LOS differed according to the severity of *** approaches to reducing LOS may be devised using knowledge of the various risk factors affecting LOS by BPD severity.

关键词： Bronchopulmonary dysplasia Length of stay Very low birth weight

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Postmortem ^(7)Li NMR analysis for assessing the reversibility of lithium metal electrodes in lithium metal batteries

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Journal of Energy Chemistry 2024年第7期94卷 430-440页

作者： Jaewon Baek Sunha kim hee-Tak kim Oc hee Han Department of Chemical&Biomolecular Engineering KAISTDaejeon 34141Republic of Korea Metropolitan Seoul Center Korea Basic Science InstituteSeoul 03759Republic of Korea Graduate School of Analytical Science&Technology Chungnam National UniversityDaejeon 34134Republic of Korea

Despite the proficiency of lithium(Li)-7 NMR spectroscopy in delineating the physical and chemical states of Li metal electrodes,challenges in specimen preparation and interpretation impede its *** this study,we conducted a comprehensive postmortem analysis utilizing ^(7)Li NMR,employing a stan-dard magic angle spinning probe to examine protective-layer coated Li metal electrodes and LiAg alloy electrodes against bare Li metal electrodes within Li metal batteries(LMBs).Our investigation explores the effects of sample burrs,alignment with the magnetic field,the existence of liquid electrolytes,and precycling on the ^(7)Li NMR *** contrasting NMR spectra before and after cycling,we identi-fied alterations in Li^(0) and Li^(+) signals attributable to the degradation of the Li metal *** NMR analyses decisively demonstrate the efficacy of the protective layer in mitigating dendrite and solid elec-trolyte interphase ***,we noted that Li*ions near the Li metal surface exhibit magnetic susceptibility anisotropy,revealing a novel approach to studying diamagnetic species on Li metal elec-trodes in *** study provides valuable insights and practical guidelines for characterizing distinct lithium states within LMBs.

关键词： NMR spectroscopy Lithium-7 Lithium metal battery Electrolyte Electrode-protective layer Solid electrolyte interface Magnetic susceptibility anisotropy Lithium-metal NMR signal Diamagnetic^(7)Li NMR signal

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Preoperative risk factors for early recurrence in patients with resectable pancreatic ductal adenocarcinoma after curative intent surgical resection

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Hepatobiliary & Pancreatic Diseases International 2018年第5期17卷 450-455页

作者： Nam hee kim Hong Joo kim Division of Gastroenterology Department of Internal Medicine Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine

Background: Postoperative early recurrence(ER) in patients with pancreatic ductal adenocarcinoma(PDAC) is frequently encountered after curative intent surgery. Nonetheless, clinical significance and risk factors of ER after surgery for PDAC have not been extensively investigated. The aim of this study was to determine preoperative risk predictors for ER in patients with PDAC after upfront surgery. Methods: Eighty-one consecutive patients with PDAC who underwent curative intent surgical resection at Kangbuk Samsung Hospital between January 2004 and May 2015 were enrolled. ER was defined as tumor relapse within 6 months after surgery. Results: ER occurred in 26 patients(32.1%), whereas 49 patients(60.5%) had late recurrence( ≥ 6 months after surgery), and 6 patients had no recurrence(7.4%). Univariate analysis showed that C-reactive protein(CRP) > 3.0 mg/dL, modified Glasgow prognostic score(mGPS) = 2, decrease of total lymphocyte count by > 50% of baseline value in the preoperative period, prognostic nutritional index(PNI) 3.0 mg/dL, decrease of total lymphocyte count by > 50% of baseline value, and preoperative SUVmax were significant and independent contributors of ER in patients with resectable PDAC who underwent curative intent surgery. Conclusions: Postoperative ER for resectable PDAC was frequent with poor prognosis after curative intent upfront surgery. It is reasonable to suggest that there is a subgroup of resectable PDAC patients at highrisk of ER and neoadjuvant therapy should be considered in these patients in a clinical trial setting.

关键词： Early recurrence Pancreatic ductal adenocarcinoma Preoperative risk factors C-reactive protein Maximum standardized uptake value

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Seasonal Prediction of Monthly Precipitation in China Using Large-Scale Climate Indices

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Advances in Atmospheric Sciences 2010年第1期27卷 47-59页

作者： Maeng-Ki kim Yeon-hee kim Department of Atmospheric Science Kongju National University

In this study, seasonal predictions were applied to precipitation in China on a monthly basis based on a multivariate linear regression with an adaptive choice of predictors drawn from regularly updated climate indices with a two to twelve month lead time. A leave-one-out cross validation was applied to obtain hindcast skill at a 1% significance level. The skill of forecast models at a monthly scale and their significance levels were evaluated using Anomaly Correlation Coefficients （ACC） and Coefficients Of Determination （COD）. The monthly ACC skill ranged between 0.43 and 0.50 in Central China, 0.41-0.57 in East China, and 0.41 0.60 in South China. The dynamic link between large-scale climate indices with lead time and the precipitation in China is also discussed based on Singular Value Decomposition Analysis （SVDA） and Correlation Analysis （CA）.

关键词： seasonal prediction precipitation in China climate predictors climate index

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